AVXL · Anavex Life Sciences Corp.

$2.86 +0.01 (+0.35%) At close · Sep 4

Russell 2000 member Rebalance outlook locked

Market Cap

$265.11M

92.70M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP →

Quarter:

Holders: 181

Total Value: $98,495,616

Total Shares: 38,037,004

Showing 1–100 of 189 holdings by value · page 1 of 2

Institutional Ownership Trend

26 quarters

Holder Concentration

Across 181 13F filers · Δ vs Mar 31, 2026

Top Holder

21.2%

+3.2 pts

Top 5

51.2%

+0.5 pts

Top 10

63.8%

+0.5 pts

HHI

764

Broadly held+86

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

Sold Out

Unchanged

Holder count: -13

Institutional value: -24.0%

Shares held: -10.0%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Large FEDERATED HERMES, INC.	+539,557	1,071,809
Large MARSHALL WACE, LLP	+470,026	889,523
Mega BlackRock, Inc.	+446,010	8,055,628
Mega GEODE CAPITAL MANAGEMENT, LLC	+219,198	2,407,473
Mega BARCLAYS PLC	+215,949	754,226

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Mega STATE STREET CORP	−2,589,258	1,922,770
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP	−1,069,934	469,629
Mega JANE STREET GROUP, LLC	−714,703	10,300
Mega CITADEL ADVISORS LLC	−524,920	647,115
Mid XTX Topco Ltd	−225,355	32,716

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Large Point72 Asset Management, L.P.	157,486	$407,888
Mid BRIDGEWAY CAPITAL MANAGEMENT, LLC	123,000	$318,570
Mid Voleon Capital Management LP	63,505	$164,477
Mega MILLENNIUM MANAGEMENT LLC	60,483	$156,650
Small Abel Hall, LLC	56,832	$147,194

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Large HRT FINANCIAL LP	657,877	$2,019,682
Small DIADEMA PARTNERS LP	477,600	$1,466,232
Large RENAISSANCE TECHNOLOGIES LLC	276,800	$849,776
Mega WELLINGTON MANAGEMENT GROUP LLP	219,090	$672,604
Large Rafferty Asset Management, LLC	143,750	$441,312

Filter: New 24 Increased 63 Reduced 59 Sold out 37 Unchanged 35

Showing 100 of 189

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

BlackRock, Inc.

$20,864,073

21.18%

8,055,628

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	247,064	$639,895	3.1%	Sole
BlackRock Asset Management Canada Ltd	403	$1,043	0.0%	Sole
BlackRock Investment Management, LLC	268,863	$696,355	3.3%	Sole
BLACKROCK ADVISORS LLC	215,433	$557,971	2.7%	Sole
BlackRock Fund Advisors	4,563,170	$11,818,610	56.6%	Sole
BlackRock Institutional Trust Company, N.A.	2,673,264	$6,923,753	33.2%	Sole
BlackRock Japan Co. Ltd	2,317	$6,001	0.0%	Sole
BlackRock Asset Management Ireland Ltd	73,934	$191,489	0.9%	Sole
Aperio Group, LLC	11,180	$28,956	0.1%	Sole

VANGUARD CAPITAL MANAGEMENT LLC

$10,501,385

10.66%

4,054,589

TWO SIGMA INVESTMENTS, LP

$7,890,533

8.01%

3,046,538

GEODE CAPITAL MANAGEMENT, LLC

$6,235,355

6.33%

2,407,473

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	342,317	$886,601	14.2%	Defined
Held directly	2,065,156	$5,348,754	85.8%	Defined

STATE STREET CORP

$4,979,974

5.06%

1,922,770

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	1,922,770	$4,979,974	100.0%	Defined

FEDERATED HERMES, INC.

$2,775,985

2.82%

1,071,809

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FEDERATED MDTA LLC	1,071,809	$2,775,985	100.0%	Defined

AQR CAPITAL MANAGEMENT LLC

$2,494,204

2.53%

963,014

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RF&L WEALTH MANAGEMENT, LLC	11	$28	0.0%	Other
Prism Planning Partners LLC	24	$62	0.0%	Other
Arax Advisory Partners	7,772	$20,129	0.8%	Other
HALBERT HARGROVE GLOBAL ADVISORS, LLC	3,207	$8,306	0.3%	Other
Stokes Family Office, LLC	2,026	$5,247	0.2%	Other
Held directly	949,974	$2,460,432	98.6%	Defined

VANGUARD PORTFOLIO MANAGEMENT LLC

$2,456,959

2.49%

948,633

Summit Financial, LLC

$2,355,423

2.39%

909,430

GOLDMAN SACHS GROUP INC

$2,306,741

2.34%

890,634

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	469,063	$1,214,873	52.7%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	421,571	$1,091,868	47.3%	Defined

MARSHALL WACE, LLP

$2,303,862

2.34%

889,523

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	834,493	$2,161,335	93.8%	Other
MARSHALL WACE ASIA Ltd	55,030	$142,527	6.2%	Other

NORTHERN TRUST CORP

$2,031,838

2.06%

784,494

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	770,062	$1,994,460	98.2%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	14,432	$37,378	1.8%	Other

BARCLAYS PLC

$1,953,444

1.98%

754,226

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS BANK PLC	753,494	$1,951,549	99.9%	Defined
BARCLAYS CAPITAL INC.	732	$1,895	0.1%	Defined

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$1,903,119

1.93%

734,795

BANK OF AMERICA CORP /DE/

$1,694,623

1.72%

654,295

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	638,683	$1,654,188	97.6%	Defined
BOFA SECURITIES, INC.	15,612	$40,435	2.4%	Defined

VANGUARD FIDUCIARY TRUST CO

$1,609,558

1.63%

621,451

UBS Group AG

$1,606,768

1.63%

620,374

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	2,900	$7,511	0.5%	Defined
UBS AG	320,574	$830,286	51.7%	Defined
UBS Switzerland AG	296,900	$768,971	47.9%	Defined

GREAT POINT PARTNERS LLC

$1,350,167

1.37%

521,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JAY JEFFREY R joint	521,300	$1,350,167	100.0%	Defined

Private Advisor Group, LLC

$1,305,360

1.33%

504,000

LPL Financial LLC

$1,051,822

1.07%

406,109

STIFEL FINANCIAL CORP

$861,425

0.87%

332,597

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STIFEL NICOLAUS & CO INC \MO\	332,505	$861,187	100.0%	Defined
Held directly	92	$238	0.0%	Defined

CITADEL ADVISORS LLC

$852,407

0.87%

329,115

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	322,886	$836,274	98.1%	Defined
Held directly	6,229	$16,133	1.9%	Defined

PVG ASSET MANAGEMENT CORP

$847,820

0.86%

327,344

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$827,580

0.84%

319,529

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	319,529	$827,580	100.0%	Other

Bank of New York Mellon Corp

$746,434

0.76%

288,199

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Investments Corporation	112,165	$290,507	38.9%	Defined
The Bank of New York Mellon	175,007	$453,268	60.7%	Defined
BNY Mellon, NA joint	1,025	$2,654	0.4%	Defined
Held directly	2	$5	0.0%	Defined

Apella Capital, LLC

$590,507

0.60%

227,995

CITADEL ADVISORS LLC

$560,217

0.57%

216,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	216,300	$560,217	100.0%	Defined

CANADA PENSION PLAN INVESTMENT BOARD

$522,662

0.53%

201,800

MORGAN STANLEY

$504,950

0.51%

194,963

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	4,803	$12,439	2.5%	Defined
MORGAN STANLEY & CO. LLC	25,594	$66,288	13.1%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	71,259	$184,560	36.6%	Defined
MORGAN STANLEY SMITH BARNEY LLC	53,393	$138,287	27.4%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	39,914	$103,376	20.5%	Defined

Nuveen, LLC

$473,249

0.48%

182,722

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	11,611	$30,072	6.4%	Defined
TEACHERS ADVISORS, LLC joint	171,111	$443,177	93.6%	Defined

Point72 Asset Management, L.P.

$407,888

0.41%

157,486

ENVESTNET ASSET MANAGEMENT INC

$378,994

0.38%

146,330

ALLIANCEBERNSTEIN L.P.

$378,917

0.38%

146,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	146,300	$378,917	100.0%	Defined

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$355,348

0.36%

137,200

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	137,200	$355,348	100.0%	Other

BRIDGEWAY CAPITAL MANAGEMENT, LLC

$318,570

0.32%

123,000

WELLS FARGO & COMPANY/MN

$302,184

0.31%

116,674

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	78,343	$202,908	67.1%	Defined
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC	22,891	$59,287	19.6%	Defined
WELLS FARGO CLEARING SERVICES, LLC	15,440	$39,989	13.2%	Defined

D. E. Shaw & Co., Inc.

$299,046

0.30%

115,462

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	115,462	$299,046	100.0%	Defined

IEQ CAPITAL, LLC

$295,902

0.30%

114,248

RHUMBLINE ADVISERS

$290,206

0.29%

112,049

Invesco Ltd.

$284,764

0.29%

109,948

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	11,553	$29,922	10.5%	Defined
Invesco Trust Co joint	36,555	$94,677	33.2%	Defined
Invesco Capital Management LLC	61,840	$160,165	56.2%	Defined

HSBC HOLDINGS PLC

$266,575

0.27%

102,925

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
HSBC BANK PLC	102,925	$266,575	100.0%	Defined

CITADEL ADVISORS LLC

$263,403

0.27%

101,700

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	101,700	$263,403	100.0%	Defined

LOS ANGELES CAPITAL MANAGEMENT LLC

$251,035

0.25%

96,925

ALPS ADVISORS INC

$243,592

0.25%

94,051

Cerity Partners LLC

$228,841

0.23%

88,356

Hikari Power Ltd

$221,665

0.23%

85,585

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Yasumitsu Shigeta	85,585	$221,665	100.0%	Defined

DEUTSCHE BANK AG\

$205,469

0.21%

79,332

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS INVESTMENT MANAGEMENT AMERICAS, INC	177	$458	0.2%	Defined
DWS Investments UK Ltd	79,155	$205,011	99.8%	Defined

Cetera Investment Advisers

$194,563

0.20%

75,121

SHEETS SMITH WEALTH MANAGEMENT

$184,560

0.19%

71,259

180 WEALTH ADVISORS, LLC

$183,967

0.19%

71,030

Mariner, LLC

$173,879

0.18%

67,135

PRICE T ROWE ASSOCIATES INC /MD/

$172,799

0.18%

66,718

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	66,718	$172,799	100.0%	Defined

PNC FINANCIAL SERVICES GROUP, INC.

$172,550

0.18%

66,622

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PNC Bank, National Association	66,622	$172,550	100.0%	Defined

LexAurum Advisors, LLC

$168,479

0.17%

65,050

Voleon Capital Management LP

$164,477

0.17%

63,505

MILLENNIUM MANAGEMENT LLC

$156,650

0.16%

60,483

FMR LLC

$155,461

0.16%

60,024

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	59,974	$155,332	99.9%	Defined
STRATEGIC ADVISERS LLC	50	$129	0.1%	Defined

Creative Planning

$154,830

0.16%

59,780

AMERIPRISE FINANCIAL INC

$153,055

0.16%

59,095

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Columbia Management Investment Advisers, LLC	105	$271	0.2%	Defined
Ameriprise Financial Services, LLC	58,990	$152,784	99.8%	Defined

Abel Hall, LLC

$147,194

0.15%

56,832

CITIGROUP INC

$139,190

0.14%

53,742

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	53,742	$139,190	100.0%	Defined

MetLife Investment Management, LLC

$133,713

0.14%

51,627

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
METLIFE INC	51,627	$133,713	100.0%	Defined

Walleye Capital LLC

$125,097

0.13%

48,300

Geneos Wealth Management Inc.

$124,579

0.13%

48,100

Hayek Kallen Investment Management

$122,012

0.12%

47,109

JPMORGAN CHASE & CO

$121,125

0.12%

46,767

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JPMorgan Chase Bank, N.A.	38,226	$99,005	81.7%	Defined
J.P. Morgan Investment Management Inc.	279	$722	0.6%	Defined
J.P. Morgan Securities plc	8,262	$21,398	17.7%	Defined

MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.

$109,953

0.11%

42,453

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Global X Management CO LLC joint	42,453	$109,953	100.0%	Defined

AXQ CAPITAL, LP

$105,537

0.11%

40,748

Snowden Capital Advisors LLC

$104,853

0.11%

40,484

Foster Victor Wealth Advisors, LLC

$103,405

0.10%

39,925

BANK OF MONTREAL /CAN/

$102,330

0.10%

39,510

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BMO Bank N.A.	35,000	$90,650	88.6%	Defined
BMO NESBITT BURNS INC.	510	$1,320	1.3%	Defined
BMO NESBITT BURNS SECURITIES LTD.	4,000	$10,360	10.1%	Defined

Squarepoint Ops LLC

$99,515

0.10%

38,423

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	38,423	$99,515	100.0%	Defined

Carnegie Investment Counsel

$99,010

0.10%

38,228

Opus Capital Group, LLC

$97,643

0.10%

37,700

NewEdge Advisors, LLC

$95,545

0.10%

36,890

OSAIC HOLDINGS, INC.

$89,266

0.09%

34,466

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
OSAIC WEALTH, INC.	25,336	$65,620	73.5%	Defined
OSAIC INSTITUTIONS, INC.	9,130	$23,646	26.5%	Defined

Vanguard Global Advisers, LLC

$88,339

0.09%

34,108

SIMPLEX TRADING, LLC

$85,182

0.09%

32,889

XTX Topco Ltd

$84,734

0.09%

32,716

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	32,716	$84,734	100.0%	Defined

WEALTH ENHANCEMENT ADVISORY SERVICES, LLC

$80,631

0.08%

31,132

Independent Advisor Alliance

$79,171

0.08%

30,568

Forum Financial Management, LP

$77,959

0.08%

30,100

Integrated Wealth Concepts LLC

$77,422

0.08%

29,893

CHOREO, LLC

$76,946

0.08%

29,709

BNP PARIBAS ARBITRAGE, SA

$75,928

0.08%

29,316

MERCER GLOBAL ADVISORS INC /ADV

$74,392

0.08%

28,723

Schonfeld Strategic Advisors LLC

$71,424

0.07%

27,577

DIMENSIONAL FUND ADVISORS LP

$70,546

0.07%

27,238

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dimensional Ireland Ltd	1,170	$3,030	4.3%	Defined
Held directly	26,068	$67,516	95.7%	Sole

MANUFACTURERS LIFE INSURANCE COMPANY, THE

$67,044

0.07%

25,886

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MANULIFE FINANCIAL CORP joint	25,886	$67,044	100.0%	Defined

Atria Investments, Inc

$66,055

0.07%

25,504

Russell Investments Group, Ltd.

$60,838

0.06%

23,490

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	23,490	$60,838	100.0%	Defined

Beacon Pointe Advisors, LLC

$60,049

0.06%

23,185

Police & Firemen's Retirement System of New Jersey

$59,808

0.06%

23,092

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Capital	23,092	$59,808	100.0%	Defined

Jain Global LLC

$56,985

0.06%

22,002

INTECH INVESTMENT MANAGEMENT LLC

$55,770

0.06%

21,533

Dana Investment Advisors, Inc.

$52,851

0.05%

20,406

TUDOR INVESTMENT CORP ET AL

$52,776

0.05%

20,377

STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM

$52,693

0.05%

20,345

Hamilton Point Investment Advisors, LLC

$52,577

0.05%

20,300

VOYA INVESTMENT MANAGEMENT LLC

$50,336

0.05%

19,435

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Voya Investment Management Co. LLC joint	19,435	$50,336	100.0%	Defined

Key facts CIK 1314052 CUSIP 032797300 13F (30d) 135 filings 135 filers Visit website