Position in AVXL
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$9,971,016
+$4,083,859 QoQ
Shares Held
3,247,888
+96.4% QoQ
Ownership
3.50%
of shares outstanding
% of Portfolio
0.01%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2022
17 quarters on record
Voting authority
Sole 98%
Shared 0%
None 2%
Common Shares in AVXL Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Mar 31, 2026TWO SIGMA INVESTMENTS, LP holds $5,506,832,621 across 316 Biotechnology names. AVXL ranks #70 (0.2% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,992,577 | $659,283,951 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
812,236 | $627,566,023 | |
| 3 | MRNA |
Moderna, Inc.
|
9,086,404 | $461,589,323 | |
| 4 | IONS |
Ionis Pharmaceuticals Inc
|
5,857,629 | $439,849,361 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
3,120,631 | $231,738,058 | |
| 6 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
378,146 | $168,857,314 | |
| 7 | RVMD |
Revolution Medicines, Inc.
|
1,558,807 | $151,593,980 | |
| 8 | VKTX |
Viking Therapeutics, Inc.
|
4,432,142 | $144,221,900 |
All Filings in AVXL
Export CSV
17 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $9,971,016 | 3,247,888 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $5,887,157 | 1,653,696 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $9,228,890 | 1,036,954 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $8,973,540 | 973,269 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $7,379,640 | 860,098 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $8,343,916 | 776,901 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $4,717,944 | 830,624 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $4,274,366 | 1,012,883 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $2,725,934 | 535,547 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $432,924 | 46,501 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $845,054 | 129,016 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $945,519 | 116,300 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $2,228,457 | 260,030 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $1,340,588 | 144,772 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $1,473,551 | 142,786 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $796,495 | 79,570 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $1,438,214 | 116,833 | Shares | Sole | 2022-05-16 | |
| No filing history on record for this holder in this stock. | ||||||