ALKS · Alkermes plc. · Holdings

$43.89 -0.23 (-0.51%)

S&P 600 member Russell 2000 member Rebalance outlook locked

Market Cap

$7.43B

167.76M

Volume · Oct 21 445.88K Avg daily vol (3M) 1.92M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP → See every holder of ALKS: 13F, 13D and 13G, insiders and funds →

Institutional holdings are being reconciled with SEC filings. Holder totals and changes may be incomplete until reconciliation finishes.

The Sep 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out. Each fund's Change is measured against its own previous reported quarter, shown in the Reported column. Pick a completed quarter in the Quarter selector below to put every fund on one quarter and see the stock-wide activity breakdown.

Quarter:

Holders: 429

Total Value: $9,416,782,138

Total Shares: 179,822,522

Showing 1–100 of 441 holdings by value · page 1 of 5

Institutional Ownership Trend

27 quarters

Superinvestors Holding ALKS

All superinvestors →

Joel Greenblatt $584,626

Holder Concentration

Across 426 13F filers

Top Holder

16.3%

of institutional value

Top 5

36.4%

of institutional value

Top 10

50.8%

of institutional value

HHI

452

Broadly held

Who Holds ALKS

Last 8 quarters through Sep 30, 2026 (filing window open)

Each kind of 13F filer's share of the common shares 13F filers report. Holder type comes from regulatory records, never the filer's name; style, turnover and horizon are measured from each filer's own 13F book. The quarter selector does not change this card.

Jun 30, 2026, the newest closed quarter: 424 filers, like-for-like change -0.4%; actively managed books -1.4%; index-like books +1.4%.

Holder type	Share	Filers	Change	New	Exited
Registered adviser	48.8%	229	+3.5%	56	28
Exempt adviser	0.6%	3	-3.9%	1	0
Adviser	4.7%	12	+24.7%	2	0
Bank	8.0%	20	-23.8%	0	2
Insurer	0.6%	3	-4.6%	0	1
Broker-dealer	0.0%	2	+10.7%	1	0
Benefit plan	0.3%	6	-16.6%	0	1
Non-US	2.9%	9	+67.3%	0	1
Holding company	21.2%	10	+3.1%	1	0
Unknown	13.0%	130	-11.4%	24	17

Style	Share	Filers	Change	New	Exited
Index-like	37.1%	43	+1.4%	1	2
Systematic-like	3.7%	22	-5.2%	10	7
Concentrated	11.8%	76	-0.9%	20	10
Diversified active	47.4%	283	-1.2%	54	30
Not measured	0.0%	0	—	0	0
Unknown	0.0%	0	-100.0%	0	1

Turnover	Share	Filers	Change	New	Exited
Low turnover	55.3%	241	-0.9%	43	18
Medium turnover	25.0%	95	+1.2%	15	13
High turnover	7.3%	47	-4.1%	19	17
Unknown	12.4%	41	+1.3%	8	2
Not measured	0.0%	0	—	0	0

Holding horizon	Share	Filers	Change	New	Exited
Short horizon	11.7%	50	+2.6%	15	6
Medium horizon	26.4%	76	-2.7%	20	13
Long horizon	56.1%	273	-2.4%	41	20
Unknown	5.9%	25	+31.0%	9	11
Not measured	0.0%	0	—	0	0

13F book size	Share	Filers	Change	New	Exited
Under $1B	2.2%	109	+16.4%	31	15
$1B to $10B	10.8%	118	+0.7%	36	16
$10B to $100B	21.3%	122	+1.9%	15	16
$100B or more	65.6%	75	-1.8%	3	3
Not measured	0.0%	0	—	0	0

Client base	Share	Filers	Change	New	Exited
Individuals and high net worth	0.6%	111	+29.1%	27	11
Pooled investment vehicles	20.3%	44	+1.0%	13	14
Registered funds and BDCs	23.1%	31	+5.2%	7	2
Pension and profit sharing plans	0.0%	3	+138.6%	1	0
Insurance companies	0.4%	3	+231.6%	0	0
Charitable organizations	0.0%	1	0.0%	0	0
Governments and sovereign funds	0.7%	5	-7.8%	2	0
Other investment advisers	0.0%	5	+12.6%	1	0
Other	0.1%	2	+86.2%	1	0
Diversified	3.5%	23	-3.3%	4	1
Corporations	0.0%	0	—	0	0
Unknown	51.2%	196	-3.9%	29	22

Private funds	Share	Filers	Change	New	Exited
Hedge funds	23.7%	60	+4.3%	17	11
Private equity funds	1.0%	11	+159.1%	3	2
Venture capital funds	0.0%	1	-100.0%	0	1
Real estate funds	0.0%	5	+35.8%	1	1
Liquidity funds	0.0%	1	new	1	0
Securitized asset funds	0.0%	1	-99.3%	0	0
Other private funds	8.1%	20	+14.3%	3	0
Mixed private funds	0.6%	3	-53.8%	0	1
Private funds, type not stated	0.1%	5	+6.2%	2	0
No private funds	15.9%	124	+1.1%	30	12
Unknown	50.6%	193	-3.9%	28	22

Location	Share	Filers	Change	New	Exited
United States	94.3%	365	-0.2%	78	39
Outside the US	5.7%	59	-5.2%	7	11

The Sep 30, 2026 filing window is still open, so its bar carries the Jun 30, 2026 positions of filers that have not filed yet.

How the mix is measured

Shares are 13F common shares restated to today's split basis; options and principal amounts are left out. The change compares only filers with a 13F in both quarters and keeps each filer in its bucket of the later quarter on both sides; a filer that continues under a new CIK is compared through its successor. Holder type comes from each filer's current regulatory profile; client base and private funds come from the Form ADV roster current at each quarter end (rosters from December 2019, so an earlier quarter reads Unknown). Style, turnover, horizon and book size are measured from each filer's 13F book in the newest measured quarter, and Not measured means none was. Actively managed books are those measured systematic-like, concentrated or diversified active.

Excluded 3 holders with no observed 2026-03-31 13F and 4 holders with no observed 2026-06-30 13F. Compared across CIK changes: JANUS HENDERSON GROUP PLC continues as Jupiter Topco LLC.

Conviction and Crowding

424 13F filers, quarter ended Jun 30, 2026

Measured across every 13F filer's common-share book once the quarter's filing window closed. Crowding counts filers with high turnover or that advise private funds on Form ADV.

Conviction holders

2.59% of filers hold it in their top 10

Mar 31, 2026: 4

Holders above 5%

median weight 0.008%

Mar 31, 2026: 1

Crowding

—

holders exceed shares outstanding: 13F filers report more shares than the cover-page count, which predates an issuance, is misstated, or misses shares lent and reported twice

Private-fund advisers

—

of shares outstanding

Institutional ownership

—

holders exceed shares outstanding: 13F filers report more shares than the cover-page count, which predates an issuance, is misstated, or misses shares lent and reported twice

Top 10 holders

51.3%

of 13F shares, Herfindahl 0.046

Active holders

-1.4%

like-for-like share change of active filers

5% stakes on record

0 13D, 5 13G (5 institutional, 0 passive, 0 exempt)

How long holders have held it value-weighted 13.9 quarters

Under 1 year 24.0% 1 to 3 years 30.9% 3 years or more 45.1% Since coverage start 0.000%

Managers in the top fifth by current three-year FundScore alpha were net buyers of $6,868,922 (1 buying, 1 selling).

Estimated Holder Cost Basis

Quarter ended Jun 30, 2026, on that quarter's share basis

Estimated, never filed: each 13F buy is costed at its quarter's average traded price and each sale keeps the average cost, so this is what holders paid on average if they traded evenly through each quarter.

Estimated avg cost

$31.26

estimated per share

Mar 31, 2026: $29.15

Quarter-end price

$52.40

implied by 13F values

Estimated gain or loss

+67.6%

price against the estimated cost

Estimated at a loss

0.000%

of costed 13F value

Estimated cost covers 35.0% of the 13F shares; positions already held when a filer's 13F history starts, or bought in a quarter without a trusted average price, have no estimate.

Shared Holders

Companies ALKS's active holders also own, quarter ended Jun 30, 2026

#	Company	Shared holders	Similarity
1	ELVN Enliven Therapeutics, Inc.	17	0.305
2	SYRE Spyre Therapeutics, Inc.	17	0.297
3	XENE Xenon Pharmaceuticals Inc.	17	0.289
4	CLDX Celldex Therapeutics, Inc.	15	0.281
5	IMVT Immunovant, Inc.	11	0.274
6	ORKA Oruka Therapeutics, Inc.	16	0.272
7	PTGX Protagonist Therapeutics, Inc	14	0.268
8	DNTH Dianthus Therapeutics, Inc. /DE/	15	0.262
9	STOK Stoke Therapeutics, Inc.	10	0.259
10	CYTK Cytokinetics Inc	19	0.259

Shareholder Targets

13F filers that own its peers but not ALKS, quarter ended Jun 30, 2026

Found through its holder-overlap peers: ELVN, SYRE, XENE, CLDX, IMVT, ORKA, PTGX, DNTH, STOK, CYTK, RLMD, INSM, GLUE, ACAD, TVTX, TNGX, IPSC, GPCR, DFTX, ERAS. 801 filers in all.

#	Filer	In peers	Of book	Largest peers
1	Avoro Capital Advisors LLC Registered adviser, Concentrated	$1,464,698,460 4 held	13.2%	CYTK, GPCR, XENE
2	FARALLON CAPITAL MANAGEMENT LLC Registered adviser, Diversified active	$1,385,694,567 3 held	8.18%	PTGX, TNGX, IMVT
3	Capital International Investors Adviser, Diversified active	$1,356,343,607 5 held	0.280%	INSM, XENE, DFTX
4	Polar Capital Holdings Plc Registered adviser, Diversified active	$1,312,559,095 11 held	3.71%	ELVN, XENE, CYTK
5	Venrock Adviser, LLC Registered adviser, Concentrated	$1,198,036,595 7 held	36.3%	ORKA, ERAS, SYRE
6	Paradigm Biocapital Advisors LP Registered adviser, Concentrated	$1,060,146,644 5 held	23.0%	SYRE, ORKA, TNGX
7	PERCEPTIVE ADVISORS LLC Registered adviser, Diversified active	$1,002,901,940 6 held	16.2%	SYRE, TVTX, ORKA
8	TCG Crossover Management, LLC Unknown, Diversified active	$943,170,003 6 held	22.7%	TNGX, IMVT, SYRE
9	Siren, L.L.C. Unknown, Diversified active	$924,966,737 10 held	18.8%	ERAS, TNGX, ELVN
10	Capital World Investors Adviser, Diversified active	$867,988,423 6 held	0.100%	ORKA, DFTX, SYRE

Fund Ownership of ALKS by Fund Type

Registered funds' Form N-PORT reports for the quarter ended Jun 30, 2026

Index funds and index ETFs hold 11.32% of shares outstanding.

Fund type	Of shares outstanding	Change	Shares	Funds
Index funds	1.32%	+0.31 pp	2,216,455	26
Index ETFs	10.00%	-0.07 pp	16,781,961	34
Active ETFs	0.92%	-2.86 pp	1,536,388	15
Active funds	3.67%	+0.96 pp	6,156,722	60
Unclassified	2.24%	+2.23 pp	3,753,685	14
All registered funds	18.15%	+0.57 pp	30,445,211	149

How fund types are measured

Each fund series counts once, with its latest Form N-PORT report dated inside the quarter; only long share positions count, restated to today's split basis. The fund type is the series' latest Form N-CEN answer on or before the quarter end (the index-fund box and the exchange-traded flag), never its name. Unclassified funds have no usable N-CEN; unit investment trusts are among them, so index ownership is a floor. Funds sit inside their advisers' 13F reports, so these shares overlap the 13F figures and are never added to them.

Holder type: Registered adviser 228 Exempt adviser 4 Adviser 12 Bank 20 Insurer 3 Broker-dealer 2 Benefit plan 6 Non-US 9 Holding company 10 Unknown 135

Showing 100 of 441

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

BlackRock, Inc.

$1,531,952,715

16.27%

29,235,739

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	456,082	$23,898,696	1.6%	Sole
BlackRock Investment Management (Australia) Ltd	115,255	$6,039,362	0.4%	Sole
BlackRock Asset Management Canada Ltd	34,399	$1,802,507	0.1%	Sole
BLACKROCK (SINGAPORE) LTD.	29,720	$1,557,328	0.1%	Sole
BlackRock Investment Management, LLC	590,137	$30,923,178	2.0%	Sole
BLACKROCK ADVISORS LLC	1,048,431	$54,937,784	3.6%	Sole
BlackRock Fund Advisors	19,451,252	$1,019,245,604	66.5%	Sole
BlackRock Institutional Trust Company, N.A.	5,607,546	$293,835,410	19.2%	Sole
BlackRock Japan Co. Ltd	67,236	$3,523,166	0.2%	Sole
BlackRock Fund Managers Ltd.	29,776	$1,560,262	0.1%	Sole
BlackRock Investment Management (UK) Ltd.	273,790	$14,346,596	0.9%	Sole
BlackRock (Netherlands) B.V.	82,880	$4,342,912	0.3%	Sole
BlackRock International, Ltd.	22,104	$1,158,249	0.1%	Sole
BlackRock Asset Management Ireland Ltd	963,359	$50,480,011	3.3%	Sole
BlackRock Advisors (UK) Ltd	48,046	$2,517,610	0.2%	Sole
BlackRock (Luxembourg) S.A.	31,141	$1,631,788	0.1%	Sole
BlackRock Life Ltd	2,526	$132,362	0.0%	Sole
BlackRock Asset Management Schweiz AG	25,116	$1,316,078	0.1%	Sole
Aperio Group, LLC	356,676	$18,689,822	1.2%	Sole
SpiderRock Advisors, LLC	267	$13,990	0.0%	Sole

BAKER BROS. ADVISORS LP

$524,642,790

5.57%

10,012,267

VANGUARD PORTFOLIO MANAGEMENT LLC

$497,318,863

5.28%

9,490,818

STATE STREET CORP

$480,014,130

5.10%

9,160,575

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS SINGAPORE LIMITED joint	9,160,575	$480,014,130	100.0%	Defined

VANGUARD CAPITAL MANAGEMENT LLC

$393,787,310

4.18%

7,515,025

PRICE T ROWE ASSOCIATES INC /MD/

$353,035,986

3.75%

6,737,328

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	253,379	$13,277,059	3.8%	Defined
Held directly	6,483,949	$339,758,927	96.2%	Sole

RENAISSANCE TECHNOLOGIES LLC

$338,552,627

3.60%

6,460,928

GEODE CAPITAL MANAGEMENT, LLC

$234,640,702

2.49%

4,477,876

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	619,201	$32,446,132	13.8%	Defined
Held directly	3,858,675	$202,194,570	86.2%	Defined

DIMENSIONAL FUND ADVISORS LP

$219,811,343

2.33%

4,194,873

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dimensional Fund Advisors Ltd.	29,861	$1,564,716	0.7%	Defined
DFA Australia Ltd.	59,002	$3,091,704	1.4%	Defined
Dimensional Fund Advisors Pte. Ltd.	1,229	$64,399	0.0%	Defined
Dimensional Ireland Ltd	296,458	$15,534,399	7.1%	Defined
Held directly	3,808,323	$199,556,125	90.8%	Sole

Deep Track Capital, LP

$209,600,000

2.23%

4,000,000

AMERICAN CENTURY COMPANIES INC

$207,202,123

2.20%

3,954,239

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AMERICAN CENTURY INVESTMENT MANAGEMENT INC	3,954,239	$207,202,123	100.0%	Defined

Holocene Advisors, LP

$188,717,132

2.00%

3,601,472

Commodore Capital LP

$157,200,000

1.67%

3,000,000

WELLINGTON MANAGEMENT GROUP LLP

$147,495,727

1.57%

2,814,804

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wellington Management Company LLP	1,954,146	$102,397,250	69.4%	Defined
Wellington Managment Canada LLC	35,193	$1,844,113	1.3%	Defined
Wellington Management Singapore Pte. Ltd.	59,146	$3,099,250	2.1%	Defined
Wellington Management International Ltd	193,572	$10,143,172	6.9%	Defined
Wellington Trust Company, NA joint	565,620	$29,638,488	20.1%	Defined
Wellington Management Australia Pty Ltd	3,296	$172,710	0.1%	Defined
Wellington Management Europe GmbH	3,831	$200,744	0.1%	Defined

PRIMECAP MANAGEMENT CO/CA/

$132,502,832

1.41%

2,528,680

FIRST TRUST ADVISORS LP

$126,861,238

1.35%

2,421,016

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$122,360,130

1.30%

2,335,117

Nuveen, LLC

$121,787,920

1.29%

2,324,197

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	586,049	$30,708,966	25.2%	Defined
TIAA CREF INVESTMENT MANAGEMENT LLC joint	703,052	$36,839,924	30.2%	Defined
TEACHERS ADVISORS, LLC joint	1,035,096	$54,239,030	44.5%	Defined

NORGES BANK

$113,017,053

1.20%

2,156,814

BVF INC/IL

$112,906,489

1.20%

2,154,704

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BVF PARTNERS L P/IL	2,154,704	$112,906,489	100.0%	Defined

GOLDMAN SACHS GROUP INC

$106,056,760

1.13%

2,023,984

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	941,494	$49,334,285	46.5%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	1,065,695	$55,842,418	52.7%	Defined
GOLDMAN SACHS INTERNATIONAL	8,081	$423,444	0.4%	Defined
Goldman Sachs Trust Company, N.A.	8,714	$456,613	0.4%	Defined

Bain Capital Life Sciences Investors, LLC

$101,547,951

1.08%

1,937,938

NORTHERN TRUST CORP

$95,976,834

1.02%

1,831,619

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	1,631,735	$85,502,914	89.1%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	118,121	$6,189,540	6.4%	Defined
MASON STREET ADVISORS, LLC joint	55,731	$2,920,304	3.0%	Other
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	26,032	$1,364,076	1.4%	Other

MORGAN STANLEY

$91,798,613

0.97%

1,751,882

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	126	$6,602	0.0%	Defined
MORGAN STANLEY & CO. LLC	68,979	$3,614,499	3.9%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	883,086	$46,273,706	50.4%	Defined
MORGAN STANLEY INVESTMENT MANAGEMENT INC	9,231	$483,704	0.5%	Defined
MORGAN STANLEY SMITH BARNEY LLC	64,066	$3,357,058	3.7%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	691,881	$36,254,563	39.5%	Defined
Calvert Research & Management	34,513	$1,808,481	2.0%	Defined

RTW INVESTMENTS, LP

$87,631,454

0.93%

1,672,356

CITADEL ADVISORS LLC

$86,203,291

0.92%

1,645,101

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	122,367	$6,412,030	7.4%	Defined
Held directly	1,522,734	$79,791,261	92.6%	Defined

LOOMIS SAYLES & CO L P

$83,081,142

0.88%

1,585,518

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
LOOMIS SAYLES TRUST COMPANY, LLC	419,256	$21,969,014	26.4%	Defined
Held directly	1,166,262	$61,112,128	73.6%	Defined

ADAGE CAPITAL PARTNERS GP, L.L.C.

$71,683,200

0.76%

1,368,000

D. E. Shaw & Co., Inc.

$68,750,423

0.73%

1,312,031

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	1,303,717	$68,314,770	99.4%	Defined
D. E. Shaw Investment Management, L.L.C. joint	8,314	$435,653	0.6%	Defined

Driehaus Capital Management LLC

$64,913,591

0.69%

1,238,809

VANGUARD FIDUCIARY TRUST CO

$61,724,318

0.66%

1,177,945

FRANKLIN RESOURCES INC

$61,320,679

0.65%

1,170,242

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FIDUCIARY TRUST CO INTERNATIONAL	155	$8,122	0.0%	Defined
FIDUCIARY TRUST INTERNATIONAL LLC	5,989	$313,823	0.5%	Defined
FRANKLIN ADVISERS INC	1,148,020	$60,156,248	98.1%	Defined
FRANKLIN ADVISORY SERVICES LLC	11,172	$585,412	1.0%	Defined
Franklin Templeton International Services S.a r.l	470	$24,628	0.0%	Defined
PUTNAM ADVISORY CO LLC	4,436	$232,446	0.4%	Defined

BNP PARIBAS ASSET MANAGEMENT Holding S.A.

$60,742,916

0.65%

1,159,216

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BNP PARIBAS ASSET MANAGEMENT Europe	2,717	$142,370	0.2%	Defined
BNP Paribas Asset Management USA, Inc.	929,922	$48,727,912	80.2%	Defined
AXA INVESTMENT MANAGERS UK LIMITED	226,577	$11,872,634	19.5%	Defined

FMR LLC

$59,443,082

0.63%

1,134,410

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	432,902	$22,684,064	38.2%	Defined
STRATEGIC ADVISERS LLC	3,324	$174,177	0.3%	Defined
Fidelity Institutional Asset Management Trust Co	587,990	$30,810,676	51.8%	Defined
FIAM LLC	110,194	$5,774,165	9.7%	Defined

Affinity Asset Advisors, LLC

$58,950,000

0.63%

1,125,000

Bank of New York Mellon Corp

$57,497,573

0.61%

1,097,282

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BNY Mellon Trust of Delaware	125	$6,550	0.0%	Defined
Mellon Investments Corporation joint	598,848	$31,379,634	54.6%	Defined
BNY Mellon Investment Adviser, Inc.	135,272	$7,088,252	12.3%	Defined
The Bank of New York Mellon	311,860	$16,341,464	28.4%	Defined
BNY Mellon, NA joint	39,453	$2,067,337	3.6%	Defined
BNY Mellon Advisors, Inc. joint	11,373	$595,945	1.0%	Other
Newton Investment Management North America, LLC	349	$18,287	0.0%	Defined
Held directly	2	$104	0.0%	Defined

T. Rowe Price Investment Management, Inc.

$57,165,622

0.61%

1,090,947

TWO SIGMA INVESTMENTS, LP

$54,407,496

0.58%

1,038,311

Soleus Capital Management, L.P.

$53,932,804

0.57%

1,029,252

PRINCIPAL FINANCIAL GROUP INC

$51,552,272

0.55%

983,822

MARSHALL WACE, LLP

$50,825,589

0.54%

969,954

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	969,954	$50,825,589	100.0%	Other

SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC

$49,792,261

0.53%

950,234

BANK OF AMERICA CORP /DE/

$48,119,074

0.51%

918,303

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	480,119	$25,158,235	52.3%	Defined
MERRILL LYNCH, PIERCE, FENNER & SMITH INC.	5,717	$299,570	0.6%	Defined
BOFA SECURITIES, INC.	59,749	$3,130,847	6.5%	Defined
MANAGED ACCOUNT ADVISORS LLC joint	372,718	$19,530,422	40.6%	Defined

VICTORY CAPITAL MANAGEMENT INC

$48,035,551

0.51%

916,709

Pictet Asset Management Holding SA

$43,912,562

0.47%

838,026

Artisan Partners Limited Partnership

$43,544,714

0.46%

831,006

PANAGORA ASSET MANAGEMENT INC

$40,114,453

0.43%

765,543

Frazier Life Sciences Management, L.P.

$36,713,902

0.39%

700,647

Public Sector Pension Investment Board

$35,496,022

0.38%

677,405

FRONTIER CAPITAL MANAGEMENT CO LLC

$34,561,048

0.37%

659,562

BNP PARIBAS ARBITRAGE, SA

$34,329,336

0.36%

655,140

AMERIPRISE FINANCIAL INC

$33,029,029

0.35%

630,325

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Columbia Management Investment Advisers, LLC	589,658	$30,898,079	93.5%	Defined
Ameriprise Financial Services, LLC	34,395	$1,802,298	5.5%	Defined
Columbia Threadneedle Management Ltd	6,272	$328,652	1.0%	Defined

Woodline Partners LP

$29,358,776

0.31%

560,282

Spruce Street Capital LP

$28,499,102

0.30%

543,876

MetLife Investment Management, LLC

$26,877,217

0.29%

512,924

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
METLIFE INC	512,924	$26,877,217	100.0%	Defined

SEGALL BRYANT & HAMILL, LLC

$26,106,832

0.28%

498,222

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NEW YORK LIFE INVESTMENT MANAGEMENT LLC	498,222	$26,106,832	100.0%	Sole

Artia Global Partners LP

$23,525,713

0.25%

448,964

Invesco Ltd.

$23,218,803

0.25%

443,107

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	65,963	$3,456,459	14.9%	Defined
Invesco Trust Co joint	66,852	$3,503,044	15.1%	Defined
Invesco Investment Advisers LLC	17,108	$896,459	3.9%	Defined
Invesco Capital Management LLC	293,184	$15,362,841	66.2%	Defined

RAYMOND JAMES FINANCIAL INC

$22,152,675

0.24%

422,761

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RAYMOND JAMES & ASSOCIATES	16,409	$859,831	3.9%	Defined
Raymond James Financial Services Advisors, Inc.	65,705	$3,442,942	15.5%	Defined
EAGLE ASSET MANAGEMENT INC joint	266,366	$13,957,578	63.0%	Defined
CHARTWELL INVESTMENT PARTNERS, LLC	74,281	$3,892,324	17.6%	Defined

Fisher Asset Management, LLC

$21,960,944

0.23%

419,102

GENDELL JEFFREY L

$20,744,216

0.22%

395,882

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Tontine Asset Management, LLC	296,911	$15,558,136	75.0%	Defined
Tontine Associates, LLC	98,971	$5,186,080	25.0%	Defined

Prosight Management, LP

$20,665,983

0.22%

394,389

Legal & General Group Plc

$20,620,657

0.22%

393,524

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Legal & General Investment Management America Inc	255,385	$13,382,174	64.9%	Defined
Legal & General Investment Management Ltd joint	138,139	$7,238,483	35.1%	Defined

RICE HALL JAMES & ASSOCIATES, LLC

$20,481,378

0.22%

390,866

RHUMBLINE ADVISERS

$20,331,147

0.22%

387,999

GLENMEDE TRUST CO NA

$18,926,041

0.20%

361,184

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Glenmede Investment Management, LP	338,025	$17,712,510	93.6%	Sole
Held directly	23,159	$1,213,531	6.4%	Sole

Holocene Advisors, LP

$18,340,000

0.19%

350,000

California Public Employees Retirement System

$18,195,690

0.19%

347,246

NOMURA ASSET MANAGEMENT INTERNATIONAL INC.

$17,661,053

0.19%

337,043

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NOMURA HOLDINGS INC joint	337,043	$17,661,053	100.0%	Defined

Ensign Peak Advisors, Inc

$17,564,899

0.19%

335,208

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$17,548,760

0.19%

334,900

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	334,900	$17,548,760	100.0%	Other

MILLENNIUM MANAGEMENT LLC

$16,746,778

0.18%

319,595

Swiss National Bank

$16,605,560

0.18%

316,900

UBS Group AG

$15,738,338

0.17%

300,350

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	24,567	$1,287,310	8.2%	Defined
UBS AG	263,429	$13,803,679	87.7%	Defined
UBS Switzerland AG	12,350	$647,140	4.1%	Defined
UBS Securities LLC	4	$209	0.0%	Defined

Eagle Health Investments LP

$15,578,624

0.17%

297,302

GW&K Investment Management, LLC

$15,321,078

0.16%

292,387

Senator Investment Group LP

$14,410,000

0.15%

275,000

JANE STREET GROUP, LLC

$14,189,920

0.15%

270,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	270,800	$14,189,920	100.0%	Defined

JPMORGAN CHASE & CO

$13,766,579

0.15%

262,721

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JPMorgan Chase Bank, N.A.	72,996	$3,824,990	27.8%	Defined
J.P. Morgan Investment Management Inc.	188,989	$9,903,023	71.9%	Defined
J.P. Morgan Securities LLC	736	$38,566	0.3%	Defined

NEUBERGER BERMAN GROUP LLC

$13,634,899

0.14%

260,208

C WorldWide Group Holding A/S

$13,100,000

0.14%

250,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Manager 2	250,000	$13,100,000	100.0%	Defined

Affinity Asset Advisors, LLC

$13,100,000

0.14%

250,000

STEMPOINT CAPITAL LP

$12,995,986

0.14%

248,015

S&CO INC

$12,825,424

0.14%

244,760

Palo Alto Investors LP

$12,710,144

0.13%

242,560

PEREGRINE CAPITAL MANAGEMENT LLC

$12,170,162

0.13%

232,255

Russell Investments Group, Ltd.

$11,665,496

0.12%

222,624

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	117,813	$6,173,400	52.9%	Defined
Russell Investments Capital, LLC	50,608	$2,651,859	22.7%	Defined
Russell Investments France SAS	19,803	$1,037,677	8.9%	Defined
Russell Investments Trust Company	34,400	$1,802,560	15.5%	Defined

FEDERATED HERMES, INC.

$11,611,263

0.12%

221,589

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FEDERATED GLOBAL INVESTMENT MANAGEMENT CORP	2,849	$149,287	1.3%	Defined
FEDERATED MDTA LLC	218,740	$11,461,976	98.7%	Defined

BARCLAYS PLC

$11,524,592

0.12%

219,935

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS BANK PLC	210,517	$11,031,090	95.7%	Defined
BARCLAYS CAPITAL INC.	7,799	$408,667	3.5%	Defined
Barclays Investment Solutions Ltd	1,619	$84,835	0.7%	Defined

ALLIANCEBERNSTEIN L.P.

$11,418,850

0.12%

217,917

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	217,917	$11,418,850	100.0%	Defined

Amundi

$11,409,523

0.12%

217,739

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Amundi Asset Management	217,739	$11,409,523	100.0%	Defined

Atle Fund Management AB

$11,178,439

0.12%

213,329

AQR CAPITAL MANAGEMENT LLC

$11,159,520

0.12%

212,968

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RF&L WEALTH MANAGEMENT, LLC	11	$576	0.0%	Other
Compound Planning, Inc.	39	$2,043	0.0%	Other
Arax Advisory Partners	515	$26,986	0.2%	Other
HALBERT HARGROVE GLOBAL ADVISORS, LLC	1,132	$59,316	0.5%	Other
Stokes Family Office, LLC	1,439	$75,403	0.7%	Other
Held directly	209,832	$10,995,196	98.5%	Defined

Rock Springs Capital Management LP

$10,470,096

0.11%

199,811

WELLS FARGO & COMPANY/MN

$10,450,288

0.11%

199,433

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	156,168	$8,183,203	78.3%	Defined
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC	29,465	$1,543,966	14.8%	Defined
WELLS FARGO CLEARING SERVICES, LLC	13,769	$721,495	6.9%	Defined
WELLS FARGO INVESTMENT INSTITUTE, INC.	31	$1,624	0.0%	Defined

CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM

$10,344,388

0.11%

197,412

Schonfeld Strategic Advisors LLC

$10,227,117

0.11%

195,174

Aberdeen Group plc

$10,155,382

0.11%

193,805

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
abrdn Inc.	193,805	$10,155,382	100.0%	Defined

DEUTSCHE BANK AG\

$10,024,957

0.11%

191,316

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS INVESTMENT MANAGEMENT AMERICAS, INC	2,515	$131,786	1.3%	Defined
DWS Investments UK Ltd	185,134	$9,701,021	96.8%	Defined
DWS International GmbH	3,667	$192,150	1.9%	Defined

Tetragon Partners GP Ltd

$9,954,899

0.11%

189,979

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Key facts CIK 1520262 CUSIP G01767105 13F (30d) 44 filings 44 filers Visit website Investor relations