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FMR LLC

Position in SYRE — Spyre Therapeutics, Inc.

CIK 315066 BOSTON, MA

Position in SYRE

as of Mar 31, 2026 · filed May 15, 2026
Position Value
$594,234,849
+$212,947,140 QoQ
Shares Held
11,781,024
+1.2% QoQ
Ownership
13.6%
of shares outstanding
% of Portfolio
0.03%
of 13F equity value
Holder Rank
not a current holder
Holding Since
Dec 2023
10 quarters on record
Voting authority Sole 100% Shared 0% None 0%

Common Shares in SYRE Over Time

Shares Held

Position Value (USD)

Position in Biotechnology

Healthcare · as of Mar 31, 2026

FMR LLC holds $49,690,752,415 across 354 Biotechnology names. SYRE ranks #24 (1.2% of the industry book) .

# Ticker Company Shares Value (USD) Open

All Filings in SYRE

Export CSV
10 filing rows on record
Report Date Value (USD) Shares
2026-03-31 $594,234,849 11,781,024
2025-12-31 $381,287,709 11,638,819
2025-09-30 $151,848,012 9,060,144
2025-06-30 $135,523,917 9,053,034
2025-03-31 $145,837,051 9,038,553
2024-12-31 $204,893,471 8,801,266
2024-09-30 $224,218,339 7,623,881
2024-06-30 $176,512,679 7,507,983
2024-03-31 $249,721,825 6,583,755
2023-12-31 $81,472,072 3,785,877