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Equibles

FRANKLIN RESOURCES INC

Position in SYRE — Spyre Therapeutics, Inc.

CIK 38777 San Mateo, CA
Back to SYRE Full portfolio

Position in SYRE

as of Jun 30, 2026 · filed Aug 13, 2026
Position Value
$130,767,877
+$86,237,781 QoQ
Shares Held
1,472,943
+66.8% QoQ
Ownership
1.67%
of shares outstanding
% of Portfolio
0.03%
of 13F equity value
Holder Rank
#21
of 266 holders
Holding Since
Dec 2023
11 quarters on record
Voting authority Sole 100% Shared 0% None 0%

Common Shares in SYRE Over Time

Shares Held

Position Value (USD)

Position in Biotechnology

Healthcare · as of Jun 30, 2026

FRANKLIN RESOURCES INC holds $9,184,405,765 across 177 Biotechnology names. SYRE ranks #14 (1.4% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 REGN
Regeneron Pharmaceuticals, Inc.
 2,771,839 $1,728,352,485
2 VRTX
Vertex Pharmaceuticals Inc / Ma
 3,347,253 $1,662,680,977
3 ASND
Ascendis Pharma A/S
 1,862,503 $496,766,798
4 JAZZ
Jazz Pharmaceuticals plc
 2,040,250 $491,639,040
5 RVMD
Revolution Medicines, Inc.
 1,488,394 $278,746,426
6 INSM
INSMED Inc
 2,273,222 $242,370,927
7 LGND
Ligand Pharmaceuticals Inc
 752,044 $237,713,585
8 ARGX
Argenx SE
 224,930 $208,683,303

All Filings in SYRE

Export CSV
11 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $130,767,877 1,472,943
2026-03-31 $44,530,096 882,833
2025-12-31 $36,339,815 1,109,274
2025-09-30 $13,328,808 795,275
2025-06-30 $11,905,266 795,275
2025-03-31 $12,272,732 760,628
2024-12-31 $17,707,745 760,642
2024-09-30 $22,371,186 760,666
2024-06-30 $17,442,163 741,904
2024-03-31 $28,140,418 741,904
2023-12-31 $14,786,176 687,090