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Equibles

STATE STREET CORP

Position in SYRE — Spyre Therapeutics, Inc.

CIK 93751 BOSTON, MA
Back to SYRE Full portfolio

Position in SYRE

as of Jun 30, 2026 · filed Aug 7, 2026
Position Value
$271,437,392
+$139,938,749 QoQ
Shares Held
3,057,416
+17.3% QoQ
Ownership
3.47%
of shares outstanding
% of Portfolio
0.01%
of 13F equity value
Holder Rank
#7
of 266 holders
Holding Since
Mar 2024
10 quarters on record
Voting authority Sole 14% Shared 0% None 86%

Common Shares in SYRE Over Time

Shares Held

Position Value (USD)

Position in Biotechnology

Healthcare · as of Jun 30, 2026

STATE STREET CORP holds $36,881,619,425 across 411 Biotechnology names. SYRE ranks #31 (0.7% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 VRTX
Vertex Pharmaceuticals Inc / Ma
 11,871,459 $5,896,909,829
2 REGN
Regeneron Pharmaceuticals, Inc.
 4,834,688 $3,014,621,355
3 INCY
Incyte Corp
 9,722,336 $1,102,124,008
4 MRNA
Moderna, Inc.
 15,726,193 $1,101,305,295
5 ALNY
Alnylam Pharmaceuticals, Inc.
 3,555,689 $1,070,369,059
6 RVMD
Revolution Medicines, Inc.
 4,897,051 $917,119,711
7 RPRX
Royalty Pharma plc
 12,338,229 $691,804,500
8 INSM
INSMED Inc
 6,052,174 $645,282,791

All Filings in SYRE

Export CSV
10 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $271,437,392 3,057,416
2026-03-31 $131,498,643 2,607,031
2025-12-31 $74,130,605 2,262,839
2025-09-30 $29,920,052 1,785,206
2025-06-30 $23,881,506 1,595,291
2025-03-31 $27,382,950 1,697,115
2024-12-31 $39,132,190 1,680,936
2024-09-30 $45,337,132 1,541,555
2024-06-30 $33,141,083 1,409,659
2024-03-31 $5,098,778 134,426