Bank of New York Mellon Corp
BankPosition in SYRE — Spyre Therapeutics, Inc.
CIK 1390777
NEW YORK, NY
Position in SYRE
as of Jun 30, 2026
· filed Aug 6, 2026
Position Value
$21,768,231
+$12,114,269 QoQ
Shares Held
245,193
+28.1% QoQ
Ownership
0.278%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#51
of 266 holders
Holding Since
Mar 2024
10 quarters on record
Voting authority
Sole 89%
Shared 0%
None 11%
Common Shares in SYRE Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Jun 30, 2026Bank of New York Mellon Corp holds $4,864,365,655 across 311 Biotechnology names. SYRE ranks #38 (0.4% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
1,672,623 | $830,842,010 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
758,492 | $472,950,091 | |
| 3 | JAZZ |
Jazz Pharmaceuticals plc
|
1,578,013 | $380,253,782 | |
| 4 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
492,071 | $148,128,128 | |
| 5 | INSM |
INSMED Inc
|
1,312,756 | $139,966,036 | |
| 6 | MRNA |
Moderna, Inc.
|
1,701,675 | $119,168,293 | |
| 7 | RVMD |
Revolution Medicines, Inc.
|
601,056 | $112,565,759 | |
| 8 | INCY |
Incyte Corp
|
972,825 | $110,279,435 |
All Filings in SYRE
Export CSV
10 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $21,768,231 | 245,193 | Shares | Defined | 2026-08-06 | |
| 2026-03-31 | $9,653,962 | 191,395 | Shares | Defined | 2026-05-05 | |
| 2025-12-31 | $6,317,109 | 192,830 | Shares | Defined | 2026-02-10 | |
| 2025-09-30 | $2,278,688 | 135,960 | Shares | Defined | 2025-11-03 | |
| 2025-06-30 | $1,978,284 | 132,150 | Shares | Defined | 2025-08-05 | |
| 2025-03-31 | $1,843,261 | 114,240 | Shares | Defined | 2025-04-29 | |
| 2024-12-31 | $2,413,856 | 103,688 | Shares | Defined | 2025-02-04 | |
| 2024-09-30 | $3,082,344 | 104,806 | Shares | Defined | 2024-11-12 | |
| 2024-06-30 | $2,766,797 | 117,686 | Shares | Defined | 2024-07-25 | |
| 2024-03-31 | $229,476 | 6,050 | Shares | Other | 2024-04-25 | |
| No filing history on record for this holder in this stock. | ||||||