JANUS HENDERSON GROUP PLC

Position in AMLX — Amylyx Pharmaceuticals, Inc.

CIK 1274173 LONDON, X0

Position in AMLX

as of Mar 31, 2026 · filed May 18, 2026 Compact

Position Value

$69,306,414

+$15,358,681 QoQ

Shares Held

4,986,073

+11.6% QoQ

Ownership

4.48%

of shares outstanding

% of Portfolio

0.04%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Jun 2023

7 quarters on record

Voting authority Sole 0.ToString("F0")% Shared 99.22584366494434.ToString("F0")% None 0.7741563350556641.ToString("F0")%

Healthcare · as of Mar 31, 2026

JANUS HENDERSON GROUP PLC holds $1,320,238,974 across 27 Drug Manufacturers - Specialty & Generic names. AMLX ranks #5 (5.2% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	ZTS	Zoetis Inc.	3,701,747	$437,583,511
2	LNTH	Lantheus Holdings, Inc.	4,774,841	$362,171,687
3	TEVA	Teva Pharmaceutical Industries Ltd	4,816,657	$145,077,707
4	BCRX	Biocryst Pharmaceuticals Inc	8,908,506	$84,808,976
5	AMLX	Amylyx Pharmaceuticals, Inc. This page	4,986,073	$69,306,414
6	NBIX	Neurocrine Biosciences Inc	466,977	$61,519,549
7	COLL	Collegium Pharmaceutical, Inc	1,825,651	$60,374,277
8	BIOA	BioAge Labs, Inc.	2,094,270	$36,628,782

7 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$69,306,414	4,986,073	+11.6%	Shares	Defined	2026-05-18
2025-12-31	$53,947,733	4,465,872	+76.1%	Shares	Defined	2026-02-17
2025-09-30	$34,467,406	2,536,233	+17133.4%	Shares	Defined	2025-11-14
2024-03-31	$41,796	14,717	-0.2%	Shares	Defined	2024-05-15
2023-12-31	$217,164	14,753	-0.0%	Shares	Defined	2024-02-14
2023-09-30	$270,145	14,754	+0.0%	Shares	Defined	2023-11-14
2023-06-30	$318,222	14,753	—	Shares	Defined	2023-08-14
No filing history on record for this holder in this stock.