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Equibles

AXSM

Axsome Therapeutics, Inc.

Company with tickers: AXSM

CIK
1579428
CUSIP
05464T104
Shares Outstanding
51,459,766
13F Activity (30d)
297 filings 285 filers

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Holders: 413
Total Value: $6,638,905,053
Total Shares: 39,278,815
Showing 1–100 of 431 holdings by value · page 1 of 5

Institutional Ownership Trend

25 quarters

Holder Concentration

Across 413 13F filers · Δ vs Dec 31, 2025
Top Holder
10.0%
Jun 2023 → Mar 2026 · range 10.0% – 11.9%
−0.7 pts
Top 5
27.5%
Jun 2023 → Mar 2026 · range 27.5% – 41.3%
−3.6 pts
Top 10
42.0%
Jun 2023 → Mar 2026 · range 42.0% – 57.5%
−2.7 pts
HHI
271
Jun 2023 → Mar 2026 · range 271 – 462
Broadly held −62

Quarterly Activity

vs Dec 31, 2025
New
71
Increased
147
Decreased
141
Sold Out
63
Unchanged
54
Holder count: +8
Institutional value: -6.5%
Shares held: +1.0%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Mega FIRST TRUST ADVISORS LP +534,066 577,479
Mid Sofinnova Investments, Inc. +400,481 412,747
Large Assenagon Asset Management S.A. +397,976 865,958
Mega FMR LLC +385,373 1,566,995
Large Point72 Asset Management, L.P. +382,351 424,750

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Mega PRICE T ROWE ASSOCIATES INC /MD/ −192,811 1,317,059
Large MARSHALL WACE, LLP −179,332 141,236
Large NOMURA ASSET MANAGEMENT INTERNATIONAL INC. −176,638 812,809
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP −176,543 444,598
Small Tri Locum Partners LP −139,511 62,116

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
Mega VANGUARD PORTFOLIO MANAGEMENT LLC 2,058,170 $347,871,893
Mega VANGUARD CAPITAL MANAGEMENT LLC 1,937,752 $327,518,843
Mega VANGUARD FIDUCIARY TRUST CO 295,139 $49,884,393
Large HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 97,550 $16,487,901
Large PEAK6 LLC 75,500 $12,761,010

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mega VANGUARD GROUP INC 4,164,818 $760,662,357
Large RTW INVESTMENTS, LP 888,001 $162,184,502
Mega NORGES BANK 495,456 $90,490,083
Mid Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. 278,835 $50,926,424
Mid Vestal Point Capital, LP 210,000 $38,354,400
Filter: New 71 Increased 147 Reduced 141 Sold out 63 Unchanged 54
Showing 100 of 431
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Open
Mega BlackRock, Inc. $661,348,886 9.96% 3,912,844
Mega VANGUARD PORTFOLIO MANAGEMENT LLC $347,871,893 5.24% 2,058,170
Mega VANGUARD CAPITAL MANAGEMENT LLC $327,518,843 4.93% 1,937,752
Mega FMR LLC $264,853,493 3.99% 1,566,995
Mega PRICE T ROWE ASSOCIATES INC /MD/ $222,609,311 3.35% 1,317,059
Mega Invesco Ltd. $219,333,531 3.30% 1,297,678
Mega GEODE CAPITAL MANAGEMENT, LLC $196,567,048 2.96% 1,162,981
Mega WELLINGTON MANAGEMENT GROUP LLP $193,579,617 2.92% 1,145,306
Mid Deep Track Capital, LP $185,922,000 2.80% 1,100,000
Mega STATE STREET CORP $166,790,457 2.51% 986,809
Large Assenagon Asset Management S.A. $146,364,221 2.20% 865,958
Large NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $137,380,977 2.07% 812,809
Large ADAGE CAPITAL PARTNERS GP, L.L.C. $124,665,433 1.88% 737,578
Small ALETHEA CAPITAL MANAGEMENT, LLC $109,713,248 1.65% 649,114
Mega D. E. Shaw & Co., Inc. $101,997,653 1.54% 603,465
Mega BANK OF AMERICA CORP /DE/ Bank $101,089,339 1.52% 598,091
Mega FIRST TRUST ADVISORS LP $97,605,500 1.47% 577,479
Mega UBS Group AG $92,486,898 1.39% 547,195
Mid EVENTIDE ASSET MANAGEMENT, LLC $87,815,693 1.32% 519,558
Mega MORGAN STANLEY $80,571,999 1.21% 476,701
Mega FRANKLIN RESOURCES INC $74,113,576 1.12% 438,490
Large Point72 Asset Management, L.P. $71,791,245 1.08% 424,750
Mega GOLDMAN SACHS GROUP INC $71,232,970 1.07% 421,447
Large Pictet Asset Management Holding SA $70,309,446 1.06% 415,983
Mega NORTHERN TRUST CORP Bank $67,854,598 1.02% 401,459
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $66,782,844 1.01% 395,118
Mid Hood River Capital Management LLC $62,791,437 0.95% 371,503
Mega PRINCIPAL FINANCIAL GROUP INC $59,239,481 0.89% 350,488
Mega Nuveen, LLC $56,746,265 0.85% 335,737
Large Qube Research & Technologies Ltd $56,678,152 0.85% 335,334
Mega TWO SIGMA INVESTMENTS, LP $54,555,937 0.82% 322,778
Mega VANGUARD FIDUCIARY TRUST CO Bank $49,884,393 0.75% 295,139
Large Driehaus Capital Management LLC $49,416,377 0.74% 292,370
Mega CITADEL ADVISORS LLC $47,579,637 0.72% 281,503
Mega JPMORGAN CHASE & CO $45,662,438 0.69% 270,160
Small PFM Health Sciences, LP $44,672,662 0.67% 264,304
Large LOOMIS SAYLES & CO L P $43,374,756 0.65% 256,625
Mid ORBIMED ADVISORS LLC $36,156,927 0.54% 213,921
Mid Sofinnova Investments, Inc. $35,958,497 0.54% 212,747
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $35,308,278 0.53% 208,900
Mega Bank of New York Mellon Corp Bank $34,926,963 0.53% 206,644
Mid FRONTIER CAPITAL MANAGEMENT CO LLC $34,322,215 0.52% 203,066
Mid Sofinnova Investments, Inc. $33,804,000 0.51% 200,000
Small First Turn Management, LLC $31,906,243 0.48% 188,772
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $31,860,270 0.48% 188,500
Mega BNP PARIBAS ARBITRAGE, SA $31,800,436 0.48% 188,146
Mega CITIGROUP INC $31,379,914 0.47% 185,658
Large VOYA INVESTMENT MANAGEMENT LLC $31,094,101 0.47% 183,967
Mega AMERIPRISE FINANCIAL INC $29,800,591 0.45% 176,314
Large RENAISSANCE TECHNOLOGIES LLC $27,769,986 0.42% 164,300
Large Woodline Partners LP $27,418,593 0.41% 162,221
Large MetLife Investment Management, LLC $25,800,057 0.39% 152,645
Mid PERCEPTIVE ADVISORS LLC $25,344,549 0.38% 149,950
Large Aberdeen Group plc $25,300,265 0.38% 149,688
Mid Voleon Capital Management LP $24,992,480 0.38% 147,867
Mega RAYMOND JAMES FINANCIAL INC $24,975,407 0.38% 147,766
Large 1832 Asset Management L.P. $24,305,076 0.37% 143,800
Large Man Group plc $24,046,644 0.36% 142,271
Large MARSHALL WACE, LLP $23,871,707 0.36% 141,236
Mid ALGERT GLOBAL LLC $22,895,449 0.34% 135,460
Large Connor, Clark & Lunn Investment Management Ltd. $22,782,543 0.34% 134,792
Large Caption Management, LLC $22,631,778 0.34% 133,900
Large US BANCORP \DE\ Bank $22,211,593 0.33% 131,414
Mega MANUFACTURERS LIFE INSURANCE COMPANY, THE Insurance $19,791,058 0.30% 117,093
Large Squarepoint Ops LLC $19,285,520 0.29% 114,102
Mega JANE STREET GROUP, LLC $18,541,494 0.28% 109,700
Large FEDERATED HERMES, INC. $18,350,670 0.28% 108,571
Large WCM INVESTMENT MANAGEMENT, LLC $18,223,229 0.27% 107,817
Mid EMERALD ADVISERS, LLC $18,188,242 0.27% 107,610
Mega CITADEL ADVISORS LLC $17,662,590 0.27% 104,500
Mega DEUTSCHE BANK AG\ Bank $17,623,037 0.27% 104,266
Mega AQR CAPITAL MANAGEMENT LLC $17,588,051 0.26% 104,059
Large HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND Pension $16,487,901 0.25% 97,550
Mega UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $16,046,247 0.24% 94,937
Mid ROYCE & ASSOCIATES LP $15,890,753 0.24% 94,017
Mega CANADA PENSION PLAN INVESTMENT BOARD Pension $15,448,428 0.23% 91,400
Large M&G PLC $15,438,117 0.23% 91,339
Large DNB Asset Management AS $15,226,673 0.23% 90,088
Mid Cannell & Spears LLC $14,223,709 0.21% 84,154
Mega JANE STREET GROUP, LLC $13,944,150 0.21% 82,500
Mid Nicholas Investment Partners, LP $13,771,411 0.21% 81,478
Mid Granite Investment Partners, LLC $13,572,136 0.20% 80,299
Mid Tortoise Investment Management, LLC $13,521,600 0.20% 80,000
Large Universal- Beteiligungs- und Servicegesellschaft mbH $11,953,939 0.18% 70,725
Large SEI INVESTMENTS CO $11,842,216 0.18% 70,064
Mega Swiss National Bank Bank $11,679,282 0.18% 69,100
Mega HSBC HOLDINGS PLC $11,569,925 0.17% 68,453
Small IRIDIAN ASSET MANAGEMENT LLC/CT $11,407,328 0.17% 67,491
Mid EMERALD MUTUAL FUND ADVISERS TRUST Mutual Fund $11,333,467 0.17% 67,054
Mid Summit Financial, LLC $11,028,385 0.17% 65,249
Large PEAK6 LLC $11,020,104 0.17% 65,200
Small Rhenman & Partners Asset Management AB $10,783,476 0.16% 63,800
Mega ALLIANCEBERNSTEIN L.P. $10,618,174 0.16% 62,822
Small Tri Locum Partners LP $10,498,846 0.16% 62,116
Large Caption Management, LLC $10,445,436 0.16% 61,800
Mega WELLS FARGO & COMPANY/MN $10,378,672 0.16% 61,405
Mid IFP Advisors, Inc $10,309,205 0.16% 60,994
Mega NEUBERGER BERMAN GROUP LLC $10,269,485 0.15% 60,759
Small Privium Fund Management B.V. $9,926,375 0.15% 58,729
Large Bridgewater Associates, LP $9,625,858 0.14% 56,951

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