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KRYS · Krystal Biotech, Inc.

Track KRYS — free
Market Cap
$10.23B
Shares
29.60M

Price & Indicators

20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$347.00 Open$349.59 Day$346.68–354.24 52W close$143.68–378.15 Avg vol 30d267K Short int3.3M · 11.3% float · 15.3d Short vol70% Last earningsAug 3, 2026 DataJan 2020–Sep 2026 Filing10-Q · Aug 3

Up next

Next earnings call
Nov 2, 2026 Est · unconfirmed · in 7 wks
filed Aug 3, 2026

Metrics snapshot

Useful current figures from the complete screener profile.

Revenue (TTM)
$440.48M
Trailing 12 months
Net income (TTM)
$241.47M
Trailing 12 months
Revenue growth YoY
+24.1%
Year over year
Operating margin
44.9%
Trailing 12 months
P / E (TTM)
43.4
Trailing earnings · reciprocal yield 2.3%
FCF yield
2.5%
TTM · current market cap
Return on invested capital
Trailing 12 months
Net cash
Latest balance sheet
Dividend yield
Trailing 12 months
Shares change YoY
+3.1%
Year over year · more shares
Price change (1Y)
+151.4%
Trailing year
Short interest
11.3%
Latest settlement · 15.3 days to cover
View all 115 metrics

AI Brief

Q2 FY26 earnings call · Aug 3, 2026
Q2 FY26

TL;DR. Krystal Biotech reported Q2 2026 global VYJUVEK revenue of $119.2 million (up 24% year-over-year), with 95% gross margin, $54.8 million in net income, and over $1.1 billion in cash. Reimbursement approvals in the U.S. surpassed 730 and the prescriber base expanded to over 640, while European launches continued with pricing discussions ongoing in Germany and France and launches in Italy and Spain expected before year-end. The clinical pipeline advanced with multiple registrational readouts slated for 2H 2026 and additional registrational study starts planned for 2027.

Bullish
  • + Global VYJUVEK revenue rose 24% year-over-year to $119.2 million with gross margin expanding to 95%.
  • + Net income grew to $54.8 million ($1.85 basic / $1.79 diluted EPS) versus $38.3 million a year ago.
  • + Cash and investments strengthened to over $1.1 billion.
  • + U.S. reimbursement approvals surpassed 730 (above the 60% initial penetration target) and the prescriber base expanded to over 640 unique prescribers.
  • + Multiple registrational data readouts are slated for 2H 2026 across IOLITE (KB803), EMERALD-1 (KB801), KYANITE-1 (inhaled KB707), and interim updates for KB407 and KB111.
Bearish
  • G&A expenses rose to $39.9 million from $35.1 million year-over-year, driven by headcount and global commercial costs.
  • Reported European/Japan revenue was broadly flat sequentially due to a reserve provision tied to ongoing German pricing negotiations.

AI-generated from the earnings call and 8-K · may contain errors · not investment advice

Equibles Rating

blended score · not investment advice
Overall
Buy
SellHoldBuy
Technical Neutral Momentum Very Strong Sentiment Neutral Fundamentals Excellent Quant / Vol Moderate
Market backdrop VIX 15.8 · calm Equity put/call 0.60
Technical
price trend
Neutral
50 / 200-day cross No cross
Price vs 200-day avg +18%
above
Price vs 50-day avg −0%
below
RSI (14) 49
neutral
MACD trend Negative
52-week position 87%
near high
Volume (OBV) Confirms
volume backs price
Momentum
relative strength
Very Strong
1-month return +6%
trailing
6-month return +38%
trailing
YTD return +41%
this year
Relative strength +20%
vs S&P · 6-mo
Sentiment
smart money
Neutral
Trend (MA cross) No cross
50d $348 › 200d $293 — 50d above 200d
Institutional flow Accumulating
+15% holders QoQ · +93 funds added
Insider flow Distributing
Net -$8.2M over 90 days · 100% sells
Short interest Rising
11.31% of float · ▲ +4.5% MoM · 15.3 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
427 holders — near 3-yr high, broad support
Squeeze score 81
high risk · 0–100
Fundamentals
Excellent
Revenue growth +34%
Y/Y
EPS growth +128%
Y/Y
Free cash flow $188.9M
Valuation P/E 43.4
in line
Quant / Vol
risk profile
Moderate
Volatility 39%
annualized · 1-yr
Max drawdown −17%
past year
ATR 3.4%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Guidance & track record

Latest guidance · from the 8-K filed Aug 3, 2026
Non-GAAP Research and Development (“R&D”) and Selling, General a · FY 2026 Non-GAAP Initiated $175M – $195M
Prior guidance period ended · from the 8-K filed Aug 5, 2024
Non-GAAP combined Research and Development and Selling, General · year ending December 31, 2024 $150M – $175M

Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.

Technicals

trend & momentum for long-term holders Neutral
1 · 4 · 2
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
+18% Bullish
Price vs 50-day avg
−0% Neutral
RSI (14)
49 Neutral
MACD trend
Negative Bearish
52-week position
87% Bullish
Volume (OBV)
Confirms Neutral
Market signals — smart money & positioning
Mixed
Trend (MA cross) No cross
50d $348 › 200d $293 — 50d above 200d
Institutional flow Accumulating
+15% holders QoQ · +93 funds added
Insider flow Distributing
Net -$8.2M over 90 days · 100% sells
Short interest Rising
11.31% of float · ▲ +4.5% MoM · 15.3 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
427 holders — near 3-yr high, broad support
Price context
position in its 52-week range
Range low $144 Now $347 · 87% Range high $378
vs 200-day avg +18% vs 50-day avg 0%

Illustrative technical + ownership context — a signal mix, not investment advice.

Key metrics

Earlier KPI extraction records exist, but do not meet the current evidence-completeness requirements. No current verified series is available. Earlier figures remain withheld until revalidated; this is not evidence that the company reports no KPIs.

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
KRYS
Krystal Biotech, Inc.
this stock
$10.23B +40.7% +33.9% 43.4 11.3%
VRTX
Vertex Pharmaceuticals Inc / Ma
$130.40B +13.7% +46.2% 30.0 1.8%
REGN
Regeneron Pharmaceuticals, Inc.
$81.67B +1.2% +20.8% 19.6 2.5%
ARGX
Argenx SE
$61.60B +17.1% 2.0%
CSLLY
Csl Ltd
$57.41B 0.0%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Accumulating
Holders
427
% held
103.9%
Net QoQ
+1.9M sh
Top holder
FMR LLC
Held Float
View
Held by Funds
Fund positions
408
View
Short & Settlement
Short Interest Rising
Shares short
3.3M
Days to cover
15.3d
Change
+142.9K sh
View
Short Volume
Short vol %
70%
As of
Sep 11, 2026
Short Total
View
Fails to Deliver
FTD shares
1.8K
Value
$580.2K
As of
Aug 14, 2026
View
Off-Exchange
Off-exchange %
40.9%
Week of
Aug 3, 2026
Off-exch Lit
View
Smart Money
Insider Trades Net selling
Net (90d)
-$8.2M
Buyers / Sellers
0 / 1
Buyers Sellers
View
Congressional Trades Buy
Member
Christopher L. Jacobs
Amount
$1.0K–$15.0K
Traded
Dec 12, 2022
View
Financials
Financials
Revenue (FY)
$389.1M
Net income (FY)
$204.8M
EPS diluted
$6.84
View
Filings
SEC Filings
Latest
8-K
Filed
Aug 3, 2026
This year
11
View
Proposed Sales
Value
$9.3M
Shares
25.0K
Filed
Sep 4, 2026
View
Earnings & Events
Earnings Calls
Last call
Sep 10, 2026
View
Investor Relations
Latest news
Krystal Biotech to Present at 202…
Published
Sep 3, 2026
View

Performance

5D 20D 120D MTD YTD
KRYS -6.6% +5.7% +37.9% -3.4% +40.8%
SPY -1.2% -1.8% +17.8% -0.4% +12.1%
vs SPY -5.4% +7.4% +20.0% -3.1% +28.7%
Key facts CIK 1711279 CUSIP 501147102 13F (30d) 161 filings 160 filers Visit website Investor relations