ANAB · Anaptysbio, Inc · Holdings

$45.65 -2.24 (-4.68%)

Russell 2000 member Rebalance outlook locked

Market Cap

$1.45B

29.10M

Volume · Oct 7 766.56K Avg daily vol (3M) 575.48K

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP →

Some SEC filings for this period have not finished importing. Holder totals and changes may be incomplete; these filings remain queued for recovery.

The Sep 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out. Each fund's Change is measured against its own previous reported quarter, shown in the Reported column. Pick a completed quarter in the Quarter selector below to put every fund on one quarter and see the stock-wide activity breakdown.

Quarter:

Holders: 215

Total Value: $2,042,948,047

Total Shares: 30,266,026

Showing 1–100 of 219 holdings by value · page 1 of 3

Institutional Ownership Trend

27 quarters

Superinvestors Holding ANAB

All superinvestors →

Joel Greenblatt $424,710

Holder Concentration

Across 215 13F filers

Top Holder

26.0%

of institutional value

Top 5

43.8%

of institutional value

Top 10

56.5%

of institutional value

HHI

842

Broadly held

Showing 100 of 219

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

EcoR1 Capital, LLC

$531,906,345

26.04%

7,880,094

BlackRock, Inc.

$124,473,305

6.09%

1,844,049

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	14,789	$998,257	0.8%	Sole
BlackRock Asset Management Canada Ltd	44	$2,970	0.0%	Sole
BlackRock Investment Management, LLC	54,232	$3,660,660	2.9%	Sole
BLACKROCK ADVISORS LLC	44,837	$3,026,497	2.4%	Sole
BlackRock Fund Advisors	953,764	$64,379,070	51.7%	Sole
BlackRock Institutional Trust Company, N.A.	634,934	$42,858,045	34.4%	Sole
BlackRock Fund Managers Ltd.	3,024	$204,120	0.2%	Sole
BlackRock Investment Management (UK) Ltd.	5,841	$394,267	0.3%	Sole
BlackRock (Netherlands) B.V.	253	$17,077	0.0%	Sole
BlackRock Asset Management Ireland Ltd	88,746	$5,990,355	4.8%	Sole
BlackRock Asset Management Schweiz AG	2,611	$176,242	0.1%	Sole
Aperio Group, LLC	40,974	$2,765,745	2.2%	Sole

TANG CAPITAL MANAGEMENT LLC

$89,834,332

4.40%

1,330,879

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
TANG KEVIN	1,330,879	$89,834,332	100.0%	Other

STATE STREET CORP

$86,818,095

4.25%

1,286,194

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	1,286,194	$86,818,095	100.0%	Defined

VANGUARD CAPITAL MANAGEMENT LLC

$61,170,727

2.99%

906,233

Affinity Asset Advisors, LLC

$55,762,357

2.73%

826,109

Sanofi

$55,479,397

2.72%

821,917

MILLENNIUM MANAGEMENT LLC

$54,493,830

2.67%

807,316

Woodline Partners LP

$48,398,445

2.37%

717,014

683 Capital Management, LLC

$44,550,000

2.18%

660,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
683 Capital Partners, LP	660,000	$44,550,000	100.0%	Defined

GEODE CAPITAL MANAGEMENT, LLC

$43,056,427

2.11%

637,873

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	75,289	$5,082,007	11.8%	Defined
Held directly	562,584	$37,974,420	88.2%	Defined

Palo Alto Investors LP

$40,735,507

1.99%

603,489

GOLDMAN SACHS GROUP INC

$39,424,725

1.93%

584,070

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	415,042	$28,015,335	71.1%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	169,028	$11,409,390	28.9%	Defined

First Light Asset Management, LLC

$39,285,270

1.92%

582,004

D. E. Shaw & Co., Inc.

$36,427,454

1.78%

539,666

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	365,181	$24,649,717	67.7%	Defined
D. E. Shaw Investment Management, L.L.C. joint	174,485	$11,777,737	32.3%	Defined

VANGUARD PORTFOLIO MANAGEMENT LLC

$35,630,415

1.74%

527,858

Apis Capital Advisors, LLC

$33,547,500

1.64%

497,000

Sofinnova Investments, Inc.

$33,313,680

1.63%

493,536

ARROWSTREET CAPITAL, LIMITED PARTNERSHIP

$32,983,942

1.61%

488,651

Nuveen, LLC

$28,394,819

1.39%

420,664

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	11,167	$753,772	2.7%	Defined
TIAA CREF INVESTMENT MANAGEMENT LLC joint	43,899	$2,963,182	10.4%	Defined
TEACHERS ADVISORS, LLC joint	365,598	$24,677,865	86.9%	Defined

BANK OF AMERICA CORP /DE/

$28,202,309

1.38%

417,812

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	290,417	$19,603,147	69.5%	Defined
BOFA SECURITIES, INC.	127,395	$8,599,162	30.5%	Defined

CITADEL ADVISORS LLC

$26,620,177

1.30%

394,373

FEDERATED HERMES, INC.

$26,437,522

1.29%

391,667

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FEDERATED EQUITY MANAGEMENT CO OF PENNSYLVANIA	9,018	$608,715	2.3%	Defined
FEDERATED GLOBAL INVESTMENT MANAGEMENT CORP	210,501	$14,208,817	53.7%	Defined
FEDERATED MDTA LLC	172,148	$11,619,990	44.0%	Defined

Squarepoint Ops LLC

$21,900,105

1.07%

324,446

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	324,446	$21,900,105	100.0%	Defined

TWO SIGMA INVESTMENTS, LP

$17,752,162

0.87%

262,995

FIRST TRUST ADVISORS LP

$17,481,757

0.86%

258,989

MORGAN STANLEY

$17,353,641

0.85%

257,091

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	2,091	$141,142	0.8%	Defined
MORGAN STANLEY & CO. LLC	14,984	$1,011,420	5.8%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	197,584	$13,336,920	76.9%	Defined
MORGAN STANLEY SMITH BARNEY LLC	8,558	$577,665	3.3%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	33,874	$2,286,494	13.2%	Defined

FMR LLC

$16,234,492

0.79%

240,511

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	77,405	$5,224,837	32.2%	Defined
STRATEGIC ADVISERS LLC	710	$47,925	0.3%	Defined
Fidelity Institutional Asset Management Trust Co	136,800	$9,234,000	56.9%	Defined
FIAM LLC	25,596	$1,727,730	10.6%	Defined

Qube Research & Technologies Ltd

$15,442,447

0.76%

228,777

HSBC HOLDINGS PLC

$14,644,057

0.72%

216,949

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
HSBC BANK PLC	216,949	$14,644,057	100.0%	Defined

Empowered Funds, LLC

$13,905,675

0.68%

206,010

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
The Burney Company	206,010	$13,905,675	100.0%	Other

NORTHERN TRUST CORP

$13,686,772

0.67%

202,767

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	186,732	$12,604,410	92.1%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	13,015	$878,512	6.4%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	3,020	$203,850	1.5%	Other

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$13,655,587

0.67%

202,305

Invesco Ltd.

$13,638,779

0.67%

202,056

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	3,066	$206,954	1.5%	Defined
Invesco Trust Co joint	7,734	$522,045	3.8%	Defined
Invesco Capital Management LLC	191,256	$12,909,780	94.7%	Defined

DIMENSIONAL FUND ADVISORS LP

$12,517,469

0.61%

185,444

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DFA Australia Ltd.	561	$37,867	0.3%	Defined
Dimensional Ireland Ltd	2,108	$142,290	1.1%	Defined
Held directly	182,775	$12,337,312	98.6%	Sole

Greenhaven Road Investment Management, L.P.

$11,546,482

0.57%

171,059

VICTORY CAPITAL MANAGEMENT INC

$11,422,822

0.56%

169,227

MACKENZIE FINANCIAL CORP

$10,191,082

0.50%

150,979

UBS Group AG

$9,911,159

0.49%

146,832

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	1,044	$70,470	0.7%	Defined
UBS AG	116,825	$7,885,687	79.6%	Defined
UBS Switzerland AG	28,903	$1,950,952	19.7%	Defined
UBS Securities LLC	60	$4,050	0.0%	Defined

VANGUARD FIDUCIARY TRUST CO

$9,903,870

0.48%

146,724

Connor, Clark & Lunn Investment Management Ltd.

$9,519,254

0.47%

141,026

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Manager 1	136,141	$9,189,517	96.5%	Sole
Held directly	4,885	$329,737	3.5%	Sole

Ensign Peak Advisors, Inc

$7,228,980

0.35%

107,096

FRANKLIN RESOURCES INC

$7,219,057

0.35%

106,949

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fiduciary Trust International of the South	29	$1,957	0.0%	Defined
FIDUCIARY TRUST INTERNATIONAL LLC	52	$3,510	0.0%	Defined
FRANKLIN ADVISERS INC	104,342	$7,043,085	97.6%	Defined
PUTNAM ADVISORY CO LLC	2,526	$170,505	2.4%	Defined

CITIGROUP INC

$6,690,195

0.33%

99,114

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	99,114	$6,690,195	100.0%	Defined

NOMURA ASSET MANAGEMENT INTERNATIONAL INC.

$6,326,910

0.31%

93,732

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NOMURA HOLDINGS INC joint	93,732	$6,326,910	100.0%	Defined

PRUDENTIAL FINANCIAL INC

$5,800,410

0.28%

85,932

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PGIM Quantitative Solutions LLC	73,132	$4,936,410	85.1%	Defined
Prudential Trust Co	12,800	$864,000	14.9%	Defined

DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main

$5,666,085

0.28%

83,942

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UNION ASSET MANAGEMENT HOLDING AG joint	83,942	$5,666,085	100.0%	Defined

JPMORGAN CHASE & CO

$5,415,929

0.27%

80,236

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JPMorgan Chase Bank, N.A.	13,388	$903,690	16.7%	Defined
J.P. Morgan Investment Management Inc.	64,448	$4,350,240	80.3%	Defined
J.P. Morgan Securities LLC	25	$1,687	0.0%	Defined
J.P. Morgan Securities plc	2,375	$160,312	3.0%	Defined

Granahan Investment Management, LLC

$5,127,435

0.25%

75,962

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$4,893,750

0.24%

72,500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	72,500	$4,893,750	100.0%	Other

Irenic Capital Management LP

$4,755,172

0.23%

70,447

Eversept Partners, LP

$4,723,852

0.23%

69,983

SG Americas Securities, LLC

$4,504,275

0.22%

66,730

JACOBS LEVY EQUITY MANAGEMENT, INC

$4,207,680

0.21%

62,336

STATE OF WISCONSIN INVESTMENT BOARD

$4,168,327

0.20%

61,753

RENAISSANCE TECHNOLOGIES LLC

$3,935,250

0.19%

58,300

VOLORIDGE INVESTMENT MANAGEMENT, LLC

$3,884,962

0.19%

57,555

Bank of New York Mellon Corp

$3,807,066

0.19%

56,401

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Investments Corporation	19,241	$1,298,767	34.1%	Defined
The Bank of New York Mellon	36,784	$2,482,920	65.2%	Defined
BNY Mellon, NA joint	375	$25,312	0.7%	Defined
Held directly	1	$67	0.0%	Defined

DEUTSCHE BANK AG\

$3,164,669

0.15%

46,884

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS Investment GmbH	27,000	$1,822,500	57.6%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC	373	$25,177	0.8%	Defined
DWS Investments UK Ltd	19,511	$1,316,992	41.6%	Defined

AQR CAPITAL MANAGEMENT LLC

$3,126,801

0.15%

46,323

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RF&L WEALTH MANAGEMENT, LLC	2	$135	0.0%	Other
Compound Planning, Inc.	3	$202	0.0%	Other
Arax Advisory Partners	161	$10,867	0.3%	Other
HALBERT HARGROVE GLOBAL ADVISORS, LLC	305	$20,587	0.7%	Other
Stokes Family Office, LLC	56	$3,780	0.1%	Other
Held directly	45,796	$3,091,230	98.9%	Defined

MARSHALL WACE, LLP

$2,957,985

0.14%

43,822

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	43,822	$2,957,985	100.0%	Other

Bleakley Financial Group, LLC

$2,886,367

0.14%

42,761

WELLINGTON MANAGEMENT GROUP LLP

$2,821,229

0.14%

41,796

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wellington Management Company LLP	13,131	$886,342	31.4%	Defined
Wellington Trust Company, NA joint	26,244	$1,771,470	62.8%	Defined
Wellington Management Australia Pty Ltd	2,421	$163,417	5.8%	Defined

WELLS FARGO & COMPANY/MN

$2,815,222

0.14%

41,707

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	40,627	$2,742,322	97.4%	Defined
WELLS FARGO CLEARING SERVICES, LLC	1,080	$72,900	2.6%	Defined

HighMark Wealth Management LLC

$2,680,830

0.13%

39,716

CAPITAL FUND MANAGEMENT S.A.

$2,642,085

0.13%

39,142

Trexquant Investment LP

$2,389,770

0.12%

35,404

Atom Investors LP

$2,289,397

0.11%

33,917

ALLIANCEBERNSTEIN L.P.

$2,215,350

0.11%

32,820

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	32,820	$2,215,350	100.0%	Defined

PRICE T ROWE ASSOCIATES INC /MD/

$2,185,245

0.11%

32,374

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	32,374	$2,185,245	100.0%	Defined

Swiss National Bank

$2,139,750

0.10%

31,700

Voleon Capital Management LP

$2,121,187

0.10%

31,425

Tema ETFs LLC

$2,110,725

0.10%

31,270

Tidal Investments LLC

$2,110,725

0.10%

31,270

Moody Aldrich Partners LLC

$2,087,505

0.10%

30,926

Aquatic Capital Management LLC

$2,079,877

0.10%

30,813

SummitTX Capital, L.P.

$1,942,582

0.10%

28,779

RHUMBLINE ADVISERS

$1,778,355

0.09%

26,346

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$1,620,000

0.08%

24,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	24,000	$1,620,000	100.0%	Other

UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC

$1,573,425

0.08%

23,310

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Group AG	304	$20,520	1.3%	Defined
UBS Asset Management Switzerland AG	23,006	$1,552,905	98.7%	Defined

BURNEY CO/

$1,522,597

0.07%

22,557

Rafferty Asset Management, LLC

$1,475,820

0.07%

21,864

XTX Topco Ltd

$1,445,242

0.07%

21,411

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	21,411	$1,445,242	100.0%	Defined

HUSSMAN STRATEGIC ADVISORS, INC.

$1,417,500

0.07%

21,000

TUDOR INVESTMENT CORP ET AL

$1,351,282

0.07%

20,019

CREDIT AGRICOLE S A

$1,350,000

0.07%

20,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Credit Agricole Corporate & Investment Bank joint	20,000	$1,350,000	100.0%	Defined

MARTINGALE ASSET MANAGEMENT L P

$1,346,085

0.07%

19,942

Creative Planning

$1,267,177

0.06%

18,773

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CREATIVE PLANNING TRUST Co LLC	2,742	$185,085	14.6%	Defined
Held directly	16,031	$1,082,092	85.4%	Sole

Y-Intercept (Hong Kong) Ltd

$1,246,590

0.06%

18,468

CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM

$1,189,957

0.06%

17,629

LOS ANGELES CAPITAL MANAGEMENT LLC

$1,183,680

0.06%

17,536

VIRGINIA RETIREMENT SYSTEMS ET Al

$1,164,375

0.06%

17,250

Diametric Capital, LP

$1,138,590

0.06%

16,868

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Thakore Nainoor	16,868	$1,138,590	100.0%	Defined

CANADA PENSION PLAN INVESTMENT BOARD

$1,113,750

0.05%

16,500

Legal & General Group Plc

$1,108,011

0.05%

16,415

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Legal & General Investment Management America Inc	1,917	$129,397	11.7%	Defined
Legal & General Investment Management Ltd joint	14,498	$978,614	88.3%	Defined

Russell Investments Group, Ltd.

$1,100,317

0.05%

16,301

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC joint	9,882	$667,035	60.6%	Defined
Russell Investments Capital, LLC joint	2,177	$146,947	13.4%	Other
Russell Investments Trust Company joint	4,242	$286,335	26.0%	Other

MASSACHUSETTS FINANCIAL SERVICES CO /MA/

$1,071,225

0.05%

15,870

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MFS Heritage Trust CO	2,576	$173,880	16.2%	Defined
Held directly	13,294	$897,345	83.8%	Sole

MILLENNIUM MANAGEMENT LLC

$1,012,500

0.05%

15,000

Cresset Asset Management, LLC

$972,810

0.05%

14,412

Vanguard Global Advisers, LLC

$939,532

0.05%

13,919

Key facts CIK 1370053 CUSIP 032724106 13F (30d) 5 filings 5 filers Visit website Investor relations