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Equibles

DNLI

Denali Therapeutics Inc.

Company with tickers: DNLI

CIK
1714899
CUSIP
24823R105
Shares Outstanding
158,709,737
13F Activity (30d)
162 filings 160 filers

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Holders: 270
Total Value: $2,846,926,527
Total Shares: 148,277,431
Showing 1–100 of 281 holdings by value · page 1 of 3

Institutional Ownership Trend

25 quarters

Holder Concentration

Across 270 13F filers · Δ vs Dec 31, 2025
Top Holder
8.8%
Jun 2023 → Mar 2026 · range 8.6% – 17.6%
+0.2 pts
Top 5
31.6%
Jun 2023 → Mar 2026 · range 31.6% – 53.5%
−3.0 pts
Top 10
49.0%
Jun 2023 → Mar 2026 · range 49.0% – 67.1%
−3.1 pts
HHI
340
Jun 2023 → Mar 2026 · range 340 – 718
Broadly held−40

Quarterly Activity

vs Dec 31, 2025
New
55
Increased
106
Decreased
57
Sold Out
35
Unchanged
52
Holder count: +20
Institutional value: +14.0%
Shares held: -2.0%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Mid ADAR1 Capital Management, LLC +1,819,339 1,871,455
Mid Vestal Point Capital, LP +1,308,326 1,773,326
Mega T. Rowe Price Investment Management, Inc. +1,265,060 8,519,192
Large Pictet Asset Management Holding SA +1,229,757 2,558,865
Large Alyeska Investment Group, L.P. +1,082,015 1,941,123

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Large Point72 Asset Management, L.P. −1,654,800 45,200
Mega FMR LLC −1,521,837 4,575,374
Mega PRICE T ROWE ASSOCIATES INC /MD/ −1,451,805 2,464,146
Mega Capital Research Global Investors −1,214,656 2,514,588
Mega ALLIANCEBERNSTEIN L.P. −664,317 2,893,618

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
Mega VANGUARD CAPITAL MANAGEMENT LLC 6,147,957 $118,040,774
Mega VANGUARD PORTFOLIO MANAGEMENT LLC 6,120,160 $117,507,072
Large Artisan Partners Limited Partnership 1,099,719 $21,114,604
Mega VANGUARD FIDUCIARY TRUST CO 949,695 $18,234,144
Mid Clearstead Advisors, LLC 737,990 $14,169,408

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mega VANGUARD GROUP INC 13,057,890 $215,585,761
Mega NORGES BANK 5,119,622 $84,524,959
Large ExodusPoint Capital Management, LP 1,023,253 $16,893,907
Large VOLORIDGE INVESTMENT MANAGEMENT, LLC 591,461 $9,765,021
Large Qube Research & Technologies Ltd 590,314 $9,746,084
Filter: New 55 Increased 106 Reduced 57 Sold out 35 Unchanged 52
Showing 100 of 281
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Open
Mega BlackRock, Inc. $250,261,125 8.79% 13,034,434
Large BAILLIE GIFFORD & CO $231,676,395 8.14% 12,066,479
Mega T. Rowe Price Investment Management, Inc. $163,568,486 5.75% 8,519,192
Large Temasek Holdings (Private) Ltd $134,649,100 4.73% 7,012,974
Mega STATE STREET CORP $120,422,419 4.23% 6,272,001
Mega VANGUARD CAPITAL MANAGEMENT LLC $118,040,774 4.15% 6,147,957
Mega VANGUARD PORTFOLIO MANAGEMENT LLC $117,507,072 4.13% 6,120,160
Mega FMR LLC $87,847,179 3.09% 4,575,374
Mega UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $85,100,425 2.99% 4,432,314
Mega GOLDMAN SACHS GROUP INC $84,619,295 2.97% 4,407,255
Large BAKER BROS. ADVISORS LP $71,648,544 2.52% 3,731,695
Mega GEODE CAPITAL MANAGEMENT, LLC $71,560,588 2.51% 3,727,114
Large Holocene Advisors, LP $61,352,236 2.16% 3,195,429
Mega ALLIANCEBERNSTEIN L.P. $55,557,465 1.95% 2,893,618
Mega DIMENSIONAL FUND ADVISORS LP $51,689,757 1.82% 2,692,175
Mega UBS Group AG $49,369,803 1.73% 2,571,344
Large Pictet Asset Management Holding SA $49,130,208 1.73% 2,558,865
Mega Capital Research Global Investors $48,280,089 1.70% 2,514,588
Mega PRICE T ROWE ASSOCIATES INC /MD/ $47,311,602 1.66% 2,464,146
Mega Fisher Asset Management, LLC $46,788,384 1.64% 2,436,895
Micro Crestline Management, L.P. $42,446,054 1.49% 2,210,732
Large Alyeska Investment Group, L.P. $37,269,561 1.31% 1,941,123
Small Lynx1 Capital Management LP $36,101,817 1.27% 1,880,303
Mid ADAR1 Capital Management, LLC $35,931,936 1.26% 1,871,455
Large Aberdeen Group plc $35,605,363 1.25% 1,854,446
Mid Casdin Capital, LLC $35,328,000 1.24% 1,840,000
Mid Vestal Point Capital, LP $34,047,859 1.20% 1,773,326
Mega PRINCIPAL FINANCIAL GROUP INC $28,386,930 1.00% 1,478,486
Mid Siren, L.L.C. $26,813,049 0.94% 1,396,513
Small Defilade Capital Management, L.P. $26,111,404 0.92% 1,359,969
Mega NORTHERN TRUST CORP Bank $25,164,593 0.88% 1,310,656
Mega MILLENNIUM MANAGEMENT LLC $24,152,640 0.85% 1,257,950
Small Foresite Capital Management VI LLC $23,231,443 0.82% 1,209,971
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $23,182,060 0.81% 1,207,399
Mega BANK OF AMERICA CORP /DE/ Bank $21,776,313 0.76% 1,134,183
Mega MORGAN STANLEY $21,211,331 0.75% 1,104,757
Large Candriam S.C.A. $21,117,024 0.74% 1,099,845
Large Artisan Partners Limited Partnership $21,114,604 0.74% 1,099,719
Large MARSHALL WACE, LLP $19,032,344 0.67% 991,268
Mega VANGUARD FIDUCIARY TRUST CO Bank $18,234,144 0.64% 949,695
Mega AMERICAN CENTURY COMPANIES INC $17,965,286 0.63% 935,692
Mega Bank of New York Mellon Corp Bank $14,746,345 0.52% 768,039
Mid Clearstead Advisors, LLC $14,169,408 0.50% 737,990
Mid Cercano Management LLC $12,000,000 0.42% 625,000
Mid MASTERS CAPITAL MANAGEMENT LLC $11,520,000 0.40% 600,000
Large Ensign Peak Advisors, Inc $9,901,843 0.35% 515,721
Mid SEGALL BRYANT & HAMILL, LLC $9,802,425 0.34% 510,543
Small STEMPOINT CAPITAL LP $8,189,971 0.29% 426,561
Large Woodline Partners LP $6,990,374 0.25% 364,082
Large Hudson Bay Capital Management LP $6,650,112 0.23% 346,360
Mega JPMORGAN CHASE & CO $6,220,586 0.22% 323,989
Small DAFNA Capital Management LLC $6,115,200 0.21% 318,500
Mega Invesco Ltd. $5,955,761 0.21% 310,196
Large BNP PARIBAS ASSET MANAGEMENT Holding S.A. $5,692,856 0.20% 296,503
Mid BRAIDWELL LP $5,689,420 0.20% 296,324
Mega Nuveen, LLC $5,675,251 0.20% 295,586
Large Marex Group plc $5,510,400 0.19% 287,000
Mega SCHRODER INVESTMENT MANAGEMENT GROUP $5,487,743 0.19% 285,820
Mega Swiss National Bank Bank $5,256,960 0.18% 273,800
Mega TD Asset Management Inc $4,910,707 0.17% 255,766
Small Privium Fund Management B.V. $4,893,254 0.17% 254,857
Small Palo Alto Investors LP $4,503,974 0.16% 234,582
Large GREAT LAKES ADVISORS, LLC $4,360,512 0.15% 227,110
Mid EDMOND DE ROTHSCHILD HOLDING S.A. $4,333,056 0.15% 225,680
Mid GROUPAMA ASSET MANAGMENT $3,976,896 0.14% 207,130
Mid Burkehill Global Management, LP $3,840,000 0.13% 200,000
Small Rhenman & Partners Asset Management AB $3,820,800 0.13% 199,000
Mid SCS Capital Management LLC $3,801,561 0.13% 197,998
Large Balyasny Asset Management L.P. $3,746,073 0.13% 195,108
Mega RHUMBLINE ADVISERS $3,537,561 0.12% 184,248
Mega CITADEL ADVISORS LLC $3,483,205 0.12% 181,417
Large TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY Pension $3,190,674 0.11% 166,181
Large Caption Management, LLC $3,129,600 0.11% 163,000
Small SECTOR GAMMA AS $3,124,032 0.11% 162,710
Large CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM Pension $3,121,459 0.11% 162,576
Mid Susquehanna Portfolio Strategies, LLC $3,031,603 0.11% 157,896
Large Rafferty Asset Management, LLC $2,893,190 0.10% 150,687
Large Man Group plc $2,669,664 0.09% 139,045
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $2,497,920 0.09% 130,100
Mega CITADEL ADVISORS LLC $2,482,560 0.09% 129,300
Large ALPS ADVISORS INC $2,478,816 0.09% 129,105
Large NEW YORK STATE COMMON RETIREMENT FUND Pension $2,459,884 0.09% 128,119
Mega MANUFACTURERS LIFE INSURANCE COMPANY, THE Insurance $2,408,486 0.08% 125,442
Mega VANGUARD ASSET MANAGEMENT, Ltd $2,404,665 0.08% 125,243
Mega DEUTSCHE BANK AG\ Bank $2,311,065 0.08% 120,368
Large NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $2,198,860 0.08% 114,524
Large B. Metzler seel. Sohn & Co. AG $2,156,160 0.08% 112,300
Large Zurcher Kantonalbank (Zurich Cantonalbank) Bank $2,144,524 0.08% 111,694
Mega Legal & General Group Plc $2,116,799 0.07% 110,250
Mid D.A. DAVIDSON & CO. $2,116,512 0.07% 110,235
Mega WELLS FARGO & COMPANY/MN $2,067,014 0.07% 107,657
Mega AQR CAPITAL MANAGEMENT LLC $1,969,514 0.07% 102,579
Mid Ghisallo Capital Management LLC $1,920,000 0.07% 100,000
Mid Integrated Wealth Concepts LLC $1,911,436 0.07% 99,554
Large Universal- Beteiligungs- und Servicegesellschaft mbH $1,910,457 0.07% 99,503
Small Greenland Capital Management LP $1,900,800 0.07% 99,000
Large MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. Mutual Fund $1,827,705 0.06% 95,193
Small Lumbard & Kellner, LLC $1,819,814 0.06% 94,782
Mega AMERIPRISE FINANCIAL INC $1,719,052 0.06% 89,534
Large STATE OF WISCONSIN INVESTMENT BOARD $1,581,254 0.06% 82,357

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