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  • DNLI Denali Therapeutics Inc.

DNLI

Denali Therapeutics Inc.

Company with tickers: DNLI

CIK
1714899
CUSIP
24823R105
Shares Outstanding
158,709,737
Price History Institutional Holders Short Volume Short Interest Fails to Deliver Financials SEC Filings Earnings Calls Insider Trades Congressional Trades
Holders: 263
Total Value: $2,543,522,092
Total Shares: 132,475,116
Showing 1–100 of 274 holdings by value · page 1 of 3

Institutional Ownership Trend

25 quarters

Holder Concentration

Across 263 13F filers · Δ vs Dec 31, 2025
Top Holder
9.8%
−0.1 pts
Top 5
35.4%
+0.8 pts
Top 10
51.2%
−0.1 pts
HHI
381
Broadly held −3

Quarterly Activity

vs Dec 31, 2025
New
258
Increased
3
Decreased
2
Sold Out
243
Unchanged
0
Holder count: +15
Institutional value: +20.1%
Shares held: +3.3%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds
Mega GOLDMAN SACHS GROUP INC +571,452 4,407,255
Large Rockefeller Capital Management L.P. +25,120 25,935
Mega VICTORY CAPITAL MANAGEMENT INC +1,130 16,194

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds
Large BNP PARIBAS ASSET MANAGEMENT Holding S.A. −294,475 2,484
Large Candriam S.C.A. −66,534 1,099,845

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD)
Mega BlackRock, Inc. 13,034,434 $250,261,125
Large BAILLIE GIFFORD & CO 12,066,479 $231,676,395
Mega T. Rowe Price Investment Management, Inc. 8,519,192 $163,568,486
Large Temasek Holdings (Private) Ltd 7,012,974 $134,649,100
Mega STATE STREET CORP 6,272,001 $120,422,419

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD)
Mega BlackRock, Inc. 12,715,201 $209,927,959
Mega BAILLIE GIFFORD & CO 12,310,889 $203,252,775
Large Temasek Holdings (Private) Ltd 7,012,974 $115,784,200
Mega STATE STREET CORP 6,263,371 $103,408,255
Mega FMR LLC 6,097,211 $100,664,951
100 of 100 shown
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Action
Mega BlackRock, Inc. $250,261,125 9.84% 13,034,434 View
Large BAILLIE GIFFORD & CO $231,676,395 9.11% 12,066,479 View
Mega T. Rowe Price Investment Management, Inc. $163,568,486 6.43% 8,519,192 View
Large Temasek Holdings (Private) Ltd $134,649,100 5.29% 7,012,974 View
Mega STATE STREET CORP $120,422,419 4.73% 6,272,001 View
Mega FMR LLC $87,847,179 3.45% 4,575,374 View
Mega UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $85,100,425 3.35% 4,432,314 View
Mega GOLDMAN SACHS GROUP INC $84,619,295 3.33% 4,407,255 View
Large BAKER BROS. ADVISORS LP $71,648,544 2.82% 3,731,695 View
Mega GEODE CAPITAL MANAGEMENT, LLC $71,560,588 2.81% 3,727,114 View
Large Holocene Advisors, LP $61,352,236 2.41% 3,195,429 View
Mega ALLIANCEBERNSTEIN L.P. $55,557,465 2.18% 2,893,618 View
Mega DIMENSIONAL FUND ADVISORS LP $51,689,757 2.03% 2,692,175 View
Mega UBS Group AG $49,369,803 1.94% 2,571,344 View
Large Pictet Asset Management Holding SA $49,130,208 1.93% 2,558,865 View
Mega Capital Research Global Investors $48,280,089 1.90% 2,514,588 View
Mega PRICE T ROWE ASSOCIATES INC /MD/ $47,311,602 1.86% 2,464,146 View
Mega Fisher Asset Management, LLC $46,788,384 1.84% 2,436,895 View
Micro Crestline Management, L.P. $42,446,054 1.67% 2,210,732 View
Large Alyeska Investment Group, L.P. $37,269,561 1.47% 1,941,123 View
Small Lynx1 Capital Management LP $36,101,817 1.42% 1,880,303 View
Mid ADAR1 Capital Management, LLC $35,931,936 1.41% 1,871,455 View
Large Aberdeen Group plc $35,605,363 1.40% 1,854,446 View
Mid Casdin Capital, LLC $35,328,000 1.39% 1,840,000 View
Mid Vestal Point Capital, LP $34,047,859 1.34% 1,773,326 View
Mega PRINCIPAL FINANCIAL GROUP INC $28,386,930 1.12% 1,478,486 View
Mid Siren, L.L.C. $26,813,049 1.05% 1,396,513 View
Small Defilade Capital Management, L.P. $26,111,404 1.03% 1,359,969 View
Mega MILLENNIUM MANAGEMENT LLC $24,152,640 0.95% 1,257,950 View
Small Foresite Capital Management VI LLC $23,231,443 0.91% 1,209,971 View
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $23,182,060 0.91% 1,207,399 View
Mega BANK OF AMERICA CORP /DE/ $21,776,313 0.86% 1,134,183 View
Large Candriam S.C.A. $21,117,024 0.83% 1,099,845 View
Large Artisan Partners Limited Partnership $21,114,604 0.83% 1,099,719 View
Large MARSHALL WACE, LLP $19,032,344 0.75% 991,268 View
Mega AMERICAN CENTURY COMPANIES INC $17,965,286 0.71% 935,692 View
Mega Bank of New York Mellon Corp $14,746,345 0.58% 768,039 View
Mid Clearstead Advisors, LLC $14,169,408 0.56% 737,990 View
Mid Cercano Management LLC $12,000,000 0.47% 625,000 View
Mid MASTERS CAPITAL MANAGEMENT LLC $11,520,000 0.45% 600,000 View
Mid SEGALL BRYANT & HAMILL, LLC $9,976,320 0.39% 519,600 View
Large Ensign Peak Advisors, Inc $9,901,843 0.39% 515,721 View
Small STEMPOINT CAPITAL LP $8,189,971 0.32% 426,561 View
Large Woodline Partners LP $6,990,374 0.27% 364,082 View
Large Hudson Bay Capital Management LP $6,650,112 0.26% 346,360 View
Mega MORGAN STANLEY $6,532,895 0.26% 340,255 View
Mega JPMORGAN CHASE & CO $6,220,586 0.24% 323,989 View
Small DAFNA Capital Management LLC $6,115,200 0.24% 318,500 View
Mega Invesco Ltd. $5,955,761 0.23% 310,196 View
Mid BRAIDWELL LP $5,689,420 0.22% 296,324 View
Mega Nuveen, LLC $5,675,251 0.22% 295,586 View
Large Marex Group plc $5,510,400 0.22% 287,000 View
Mega SCHRODER INVESTMENT MANAGEMENT GROUP $5,487,743 0.22% 285,820 View
Mega Swiss National Bank $5,256,960 0.21% 273,800 View
Mega TD Asset Management Inc $4,910,707 0.19% 255,766 View
Small Privium Fund Management B.V. $4,893,254 0.19% 254,857 View
Small Palo Alto Investors LP $4,503,974 0.18% 234,582 View
Large GREAT LAKES ADVISORS, LLC $4,360,512 0.17% 227,110 View
Mid EDMOND DE ROTHSCHILD HOLDING S.A. $4,333,056 0.17% 225,680 View
Mid GROUPAMA ASSET MANAGMENT $3,976,896 0.16% 207,130 View
Mid Burkehill Global Management, LP $3,840,000 0.15% 200,000 View
Small Rhenman & Partners Asset Management AB $3,820,800 0.15% 199,000 View
Mid SCS Capital Management LLC $3,801,561 0.15% 197,998 View
Large Balyasny Asset Management L.P. $3,746,073 0.15% 195,108 View
Mega RHUMBLINE ADVISERS $3,537,561 0.14% 184,248 View
Mega CITADEL ADVISORS LLC $3,483,205 0.14% 181,417 View
Mid TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY $3,190,674 0.13% 166,181 View
Large Caption Management, LLC $3,129,600 0.12% 163,000 View
Small SECTOR GAMMA AS $3,124,032 0.12% 162,710 View
Large CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $3,121,459 0.12% 162,576 View
Mid Susquehanna Portfolio Strategies, LLC $3,031,603 0.12% 157,896 View
Large Rafferty Asset Management, LLC $2,893,190 0.11% 150,687 View
Large Man Group plc $2,669,664 0.10% 139,045 View
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $2,497,920 0.10% 130,100 View
Mega CITADEL ADVISORS LLC $2,482,560 0.10% 129,300 View
Large ALPS ADVISORS INC $2,478,816 0.10% 129,105 View
Large NEW YORK STATE COMMON RETIREMENT FUND $2,459,884 0.10% 128,119 View
Mega MANUFACTURERS LIFE INSURANCE COMPANY, THE $2,408,486 0.09% 125,442 View
Mega DEUTSCHE BANK AG\ $2,311,065 0.09% 120,368 View
Large NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $2,198,860 0.09% 114,524 View
Large B. Metzler seel. Sohn & Co. AG $2,156,160 0.08% 112,300 View
Large Zurcher Kantonalbank (Zurich Cantonalbank) $2,144,524 0.08% 111,694 View
Mega Legal & General Group Plc $2,116,799 0.08% 110,250 View
Mid D.A. DAVIDSON & CO. $2,116,512 0.08% 110,235 View
Mega WELLS FARGO & COMPANY/MN $2,067,014 0.08% 107,657 View
Mega AQR CAPITAL MANAGEMENT LLC $1,969,514 0.08% 102,579 View
Mid Ghisallo Capital Management LLC $1,920,000 0.08% 100,000 View
Mid Integrated Wealth Concepts LLC $1,911,436 0.08% 99,554 View
Large Universal- Beteiligungs- und Servicegesellschaft mbH $1,910,457 0.08% 99,503 View
Small Greenland Capital Management LP $1,900,800 0.07% 99,000 View
Large MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $1,827,705 0.07% 95,193 View
Small Lumbard & Kellner, LLC $1,819,814 0.07% 94,782 View
Mega AMERIPRISE FINANCIAL INC $1,719,052 0.07% 89,534 View
Large STATE OF WISCONSIN INVESTMENT BOARD $1,581,254 0.06% 82,357 View
Mega JANE STREET GROUP, LLC $1,545,600 0.06% 80,500 View
Mid XTX Topco Ltd $1,508,486 0.06% 78,567 View
Mid Y-Intercept (Hong Kong) Ltd $1,497,734 0.06% 78,007 View
Large MetLife Investment Management, LLC $1,489,113 0.06% 77,558 View
Large Caption Management, LLC $1,432,320 0.06% 74,600 View
Large Creative Planning $1,422,124 0.06% 74,069 View
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