DNLI · Denali Therapeutics Inc.

$24.02 -0.91 (-3.63%)

Market Cap

$3.98B

159.85M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Quarter:

Holders: 293

Total Value: $4,043,035,962

Total Shares: 157,254,065

Institutional Ownership Trend

26 quarters

Holder Concentration

Across 293 13F filers · Δ vs Mar 31, 2026

Top Holder

10.3%

+1.5 pts

Top 5

35.8%

+4.1 pts

Top 10

51.9%

+3.0 pts

HHI

397

Broadly held+57

Quarterly Activity

vs Mar 31, 2026

New

Increased

123

Decreased

Sold Out

Unchanged

Holder count: +21

Institutional value: +42.0%

Shares held: +6.1%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Mega T. Rowe Price Investment Management, Inc.	+7,659,771	16,178,963
Large NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	+2,093,739	2,208,263
Large BNP PARIBAS ASSET MANAGEMENT Holding S.A.	+1,059,011	1,355,514
Mega BlackRock, Inc.	+991,979	14,026,413
Mega STATE STREET CORP	+777,303	7,049,304

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Small Lynx1 Capital Management LP	−1,868,645	11,658
Large Alyeska Investment Group, L.P.	−1,721,789	219,334
Mega UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	−1,270,342	3,161,972
Small Defilade Capital Management, L.P.	−968,103	391,866
Mid ADAR1 Capital Management, LLC	−842,375	1,029,080

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Mega NORGES BANK	2,824,746	$72,652,467
Large ExodusPoint Capital Management, LP	336,567	$8,656,503
Mid E. Ohman J:or Asset Management AB	160,000	$4,115,200
Small Odyssean, LLC	125,062	$3,216,594
Mid PFM Health Sciences, LP	100,966	$2,596,845

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Mid Vestal Point Capital, LP	1,773,326	$34,047,859
Small STEMPOINT CAPITAL LP	426,561	$8,189,971
Mid BRAIDWELL LP	296,324	$5,689,420
Mega SCHRODER INVESTMENT MANAGEMENT GROUP	285,820	$5,487,743
Large Caption Management, LLC	237,600	$4,561,920

Filter: New 54 Increased 123 Reduced 67 Sold out 33 Unchanged 49

Showing 100 of 298

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

T. Rowe Price Investment Management, Inc.

$416,122,928

10.29%

16,178,963

BlackRock, Inc.

$360,759,334

8.92%

14,026,413

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	200,029	$5,144,745	1.4%	Sole
BlackRock Investment Management (Australia) Ltd	319	$8,204	0.0%	Sole
BlackRock Asset Management Canada Ltd	24,882	$639,965	0.2%	Sole
BlackRock Investment Management, LLC	465,277	$11,966,924	3.3%	Sole
BLACKROCK ADVISORS LLC	996,481	$25,629,491	7.1%	Sole
BlackRock Fund Advisors	7,006,360	$180,203,579	50.0%	Sole
BlackRock Institutional Trust Company, N.A.	4,801,701	$123,499,749	34.2%	Sole
BlackRock Japan Co. Ltd	10,852	$279,113	0.1%	Sole
BlackRock Fund Managers Ltd.	24,952	$641,765	0.2%	Sole
BlackRock Investment Management (UK) Ltd.	64,187	$1,650,889	0.5%	Sole
BlackRock (Netherlands) B.V.	1,727	$44,418	0.0%	Sole
BlackRock Asset Management Ireland Ltd	264,930	$6,813,999	1.9%	Sole
BlackRock (Luxembourg) S.A.	5,079	$130,631	0.0%	Sole
BlackRock Life Ltd	319	$8,204	0.0%	Sole
BlackRock Asset Management Schweiz AG	24,287	$624,661	0.2%	Sole
Aperio Group, LLC	134,578	$3,461,346	1.0%	Sole
SpiderRock Advisors, LLC	453	$11,651	0.0%	Sole

BAILLIE GIFFORD & CO

$307,617,113

7.61%

11,960,230

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BAILLIE GIFFORD & CO LTD	1,216,954	$31,300,056	10.2%	Defined
BAILLIE GIFFORD OVERSEAS LTD	3,106,928	$79,910,188	26.0%	Defined
Baillie Gifford Investment Management (Europe) Ltd	58,768	$1,511,512	0.5%	Defined
Held directly	7,577,580	$194,895,357	63.4%	Sole

STATE STREET CORP

$181,308,098

4.48%

7,049,304

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	7,049,304	$181,308,098	100.0%	Defined

Temasek Holdings (Private) Ltd

$180,373,691

4.46%

7,012,974

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Aranda Investments Pte. Ltd. joint	7,012,974	$180,373,691	100.0%	Defined

VANGUARD PORTFOLIO MANAGEMENT LLC

$166,589,906

4.12%

6,477,057

VANGUARD CAPITAL MANAGEMENT LLC

$161,411,749

3.99%

6,275,729

FMR LLC

$116,661,701

2.89%

4,535,836

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	2,460,202	$63,276,395	54.2%	Defined
FIDELITY MANAGEMENT TRUST CO	2,061,709	$53,027,155	45.5%	Defined
STRATEGIC ADVISERS LLC	13,925	$358,151	0.3%	Defined

GOLDMAN SACHS GROUP INC

$106,889,618

2.64%

4,155,895

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	903,675	$23,242,521	21.7%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	3,212,243	$82,618,889	77.3%	Defined
Goldman Sachs Trust Company, N.A. joint	39,977	$1,028,208	1.0%	Other

GEODE CAPITAL MANAGEMENT, LLC

$102,194,355

2.53%

3,973,342

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	560,341	$14,411,970	14.1%	Defined
Held directly	3,413,001	$87,782,385	85.9%	Defined

Holocene Advisors, LP

$100,442,387

2.48%

3,905,225

BAKER BROS. ADVISORS LP

$96,047,121

2.38%

3,734,336

UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC

$81,325,915

2.01%

3,161,972

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Group AG	35,935	$924,248	1.1%	Defined
UBS Asset Management Switzerland AG	1,938,845	$49,867,093	61.3%	Defined
UBS Asset Management (UK) Ltd.	48,749	$1,253,822	1.5%	Sole
Held directly	1,138,443	$29,280,752	36.0%	Sole

PRICE T ROWE ASSOCIATES INC /MD/

$80,661,752

2.00%

3,136,149

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	214,642	$5,520,592	6.8%	Defined
Held directly	2,921,507	$75,141,160	93.2%	Sole

UBS Group AG

$80,261,624

1.99%

3,120,592

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	86,797	$2,232,418	2.8%	Defined
UBS AG	1,675,590	$43,096,174	53.7%	Defined
UBS Switzerland AG	1,358,205	$34,933,032	43.5%	Defined

ALLIANCEBERNSTEIN L.P.

$76,769,236

1.90%

2,984,807

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	2,984,807	$76,769,236	100.0%	Defined

DIMENSIONAL FUND ADVISORS LP

$73,574,732

1.82%

2,860,604

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dimensional Fund Advisors Ltd.	26,397	$678,930	0.9%	Defined
DFA Australia Ltd.	45,041	$1,158,454	1.6%	Defined
Dimensional Fund Advisors Pte. Ltd.	919	$23,636	0.0%	Defined
Dimensional Ireland Ltd	104,264	$2,681,670	3.6%	Defined
Held directly	2,683,983	$69,032,042	93.8%	Sole

NORGES BANK

$72,652,467

1.80%

2,824,746

Pictet Asset Management Holding SA

$71,789,818

1.78%

2,791,206

Capital Research Global Investors

$65,992,813

1.63%

2,565,817

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CAPITAL GROUP COMPANIES INC joint	2,565,817	$65,992,813	100.0%	Defined

Fisher Asset Management, LLC

$62,092,246

1.54%

2,414,162

NOMURA ASSET MANAGEMENT INTERNATIONAL INC.

$56,796,524

1.40%

2,208,263

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NOMURA HOLDINGS INC joint	2,208,263	$56,796,524	100.0%	Defined

Casdin Capital, LLC

$52,597,400

1.30%

2,045,000

Crestline Management, L.P.

$49,144,027

1.22%

1,910,732

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Rithm Capital Corp.	1,910,732	$49,144,027	100.0%	Defined

PRINCIPAL FINANCIAL GROUP INC

$36,524,534

0.90%

1,420,083

Foresite Capital Management VI LLC

$35,924,950

0.89%

1,396,771

Siren, L.L.C.

$35,918,314

0.89%

1,396,513

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invus Group, LLC	1,396,513	$35,918,314	100.0%	Defined

NORTHERN TRUST CORP

$35,744,753

0.88%

1,389,765

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	1,270,757	$32,683,869	91.4%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	96,189	$2,473,980	6.9%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	22,819	$586,904	1.6%	Other

BNP PARIBAS ASSET MANAGEMENT Holding S.A.

$34,863,820

0.86%

1,355,514

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BNP PARIBAS ASSET MANAGEMENT Europe	1,964	$50,514	0.1%	Defined
BNP Paribas Asset Management USA, Inc.	1,071,650	$27,562,838	79.1%	Defined
AXA INVESTMENT MANAGERS UK LIMITED	281,900	$7,250,468	20.8%	Defined

Aberdeen Group plc

$34,605,771

0.86%

1,345,481

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
abrdn Inc.	1,345,481	$34,605,771	100.0%	Defined

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$32,020,242

0.79%

1,244,955

BANK OF AMERICA CORP /DE/

$31,660,212

0.78%

1,230,957

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	419,510	$10,789,797	34.1%	Defined
MERRILL LYNCH, PIERCE, FENNER & SMITH INC.	38,897	$1,000,430	3.2%	Defined
BOFA SECURITIES, INC.	472,716	$12,158,255	38.4%	Defined
MANAGED ACCOUNT ADVISORS LLC joint	299,834	$7,711,730	24.4%	Defined

Artisan Partners Limited Partnership

$31,494,062

0.78%

1,224,497

Candriam S.C.A.

$30,603,867

0.76%

1,189,886

MILLENNIUM MANAGEMENT LLC

$28,954,238

0.72%

1,125,748

ADAR1 Capital Management, LLC

$26,467,937

0.65%

1,029,080

VANGUARD FIDUCIARY TRUST CO

$25,511,770

0.63%

991,904

MORGAN STANLEY

$24,718,201

0.61%

961,050

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	19,104	$491,354	2.0%	Defined
MORGAN STANLEY & CO. LLC	43,461	$1,117,816	4.5%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	137,364	$3,533,002	14.3%	Defined
MORGAN STANLEY INVESTMENT MANAGEMENT INC	1,286	$33,075	0.1%	Defined
MORGAN STANLEY SMITH BARNEY LLC	277,926	$7,148,256	28.9%	Defined
Morgan Stanley Strategic Investments, Inc	1	$25	0.0%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	421,908	$10,851,473	43.9%	Defined
EATON VANCE MANAGEMENT	60,000	$1,543,200	6.2%	Defined

Bank of New York Mellon Corp

$20,583,271

0.51%

800,283

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BNY Mellon Trust of Delaware joint	235	$6,043	0.0%	Defined
Mellon Investments Corporation joint	193,221	$4,969,643	24.1%	Defined
BNY Mellon Securities Corporation	10,017	$257,637	1.3%	Defined
The Bank of New York Mellon	263,947	$6,788,716	33.0%	Defined
BNY Mellon, NA joint	48,122	$1,237,697	6.0%	Defined
BNY Mellon Advisors, Inc.	11,318	$291,098	1.4%	Defined
Newton Investment Management North America, LLC joint	273,422	$7,032,412	34.2%	Defined
Held directly	1	$25	0.0%	Defined

DAFNA Capital Management LLC

$19,007,440

0.47%

739,014

AMERICAN CENTURY COMPANIES INC

$18,326,168

0.45%

712,526

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AMERICAN CENTURY INVESTMENT MANAGEMENT INC	712,526	$18,326,168	100.0%	Defined

Cercano Management LLC

$16,075,000

0.40%

625,000

Nuveen, LLC

$15,662,630

0.39%

608,967

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	91,830	$2,361,867	15.1%	Defined
TIAA CREF INVESTMENT MANAGEMENT LLC joint	219,227	$5,638,518	36.0%	Defined
TEACHERS ADVISORS, LLC joint	297,910	$7,662,245	48.9%	Defined

Ensign Peak Advisors, Inc

$14,986,246

0.37%

582,669

MARSHALL WACE, LLP

$14,141,625

0.35%

549,830

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	520,647	$13,391,039	94.7%	Other
MARSHALL WACE ASIA Ltd	29,183	$750,586	5.3%	Other

SEGALL BRYANT & HAMILL, LLC

$13,361,102

0.33%

519,483

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NEW YORK LIFE INVESTMENT MANAGEMENT LLC	519,483	$13,361,102	100.0%	Sole

CITIGROUP INC

$12,532,789

0.31%

487,278

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	487,278	$12,532,789	100.0%	Defined

CITADEL ADVISORS LLC

$11,723,176

0.29%

455,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	455,800	$11,723,176	100.0%	Defined

Balyasny Asset Management L.P.

$11,131,616

0.28%

432,800

Defilade Capital Management, L.P.

$10,078,793

0.25%

391,866

AQR CAPITAL MANAGEMENT LLC

$9,991,418

0.25%

388,469

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RF&L WEALTH MANAGEMENT, LLC	22	$565	0.0%	Other
Prism Planning Partners LLC	152	$3,909	0.0%	Other
Compound Planning, Inc.	19	$488	0.0%	Other
Arax Advisory Partners	1,093	$28,111	0.3%	Other
HALBERT HARGROVE GLOBAL ADVISORS, LLC	1,212	$31,172	0.3%	Other
Stokes Family Office, LLC	340	$8,744	0.1%	Other
Held directly	385,631	$9,918,429	99.3%	Defined

Woodline Partners LP

$9,364,189

0.23%

364,082

Invesco Ltd.

$8,845,055

0.22%

343,898

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	19,531	$502,336	5.7%	Defined
Invesco Trust Co joint	58,632	$1,508,015	17.0%	Defined
Invesco Capital Management LLC	265,735	$6,834,704	77.3%	Defined

ExodusPoint Capital Management, LP

$8,656,503

0.21%

336,567

Marex Group plc

$7,603,629

0.19%

295,631

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marex Financial	295,631	$7,603,629	100.0%	Defined

JPMORGAN CHASE & CO

$7,382,126

0.18%

287,019

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
J.P. Morgan Trust Co of Delaware	324	$8,333	0.1%	Other
JPMorgan Chase Bank, N.A.	73,463	$1,889,468	25.6%	Defined
J.P. Morgan Investment Management Inc.	201,354	$5,178,824	70.2%	Defined
J.P. Morgan Securities LLC	33	$848	0.0%	Defined
J.P. Morgan Securities plc	11,845	$304,653	4.1%	Defined

Swiss National Bank

$6,957,260

0.17%

270,500

TD Asset Management Inc

$5,957,883

0.15%

231,644

GROUPAMA ASSET MANAGMENT

$5,914,031

0.15%

229,939

Privium Fund Management B.V.

$5,911,922

0.15%

229,857

XTX Topco Ltd

$5,837,231

0.14%

226,953

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	226,953	$5,837,231	100.0%	Defined

Alyeska Investment Group, L.P.

$5,641,270

0.14%

219,334

Susquehanna Portfolio Strategies, LLC

$5,439,111

0.13%

211,474

MASTERS CAPITAL MANAGEMENT LLC

$5,144,000

0.13%

200,000

Burkehill Global Management, LP

$5,144,000

0.13%

200,000

SCS Capital Management LLC

$5,092,508

0.13%

197,998

RHUMBLINE ADVISERS

$5,009,921

0.12%

194,787

WELLS FARGO & COMPANY/MN

$4,883,325

0.12%

189,865

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	128,236	$3,298,229	67.5%	Defined
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC	49,323	$1,268,587	26.0%	Defined
WELLS FARGO CLEARING SERVICES, LLC	12,227	$314,478	6.4%	Defined
WELLS FARGO INVESTMENT INSTITUTE, INC.	79	$2,031	0.0%	Defined

Universal- Beteiligungs- und Servicegesellschaft mbH

$4,608,895

0.11%

179,195

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Universal-Investment-Gesellschaft mbH	179,195	$4,608,895	100.0%	Defined

Rhenman & Partners Asset Management AB

$4,603,880

0.11%

179,000

NEW YORK STATE COMMON RETIREMENT FUND

$4,416,432

0.11%

171,712

TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY

$4,274,174

0.11%

166,181

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BAILLIE GIFFORD US EQUITY GROWTH STRATEGY	136,276	$3,505,018	82.0%	Sole
LIFE BAILLIE GIFFORD US EQUITY GROWTH	1,207	$31,044	0.7%	Sole
MED BAILLIE GIFFORD US EQ GROWTH	28,698	$738,112	17.3%	Sole

EDMOND DE ROTHSCHILD HOLDING S.A.

$4,245,857

0.11%

165,080

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
EDMOND DE ROTHSCHILD ASSET MANAGEMENT (FRANCE)	165,080	$4,245,857	100.0%	Sole

ALPS ADVISORS INC

$4,124,922

0.10%

160,378

E. Ohman J:or Asset Management AB

$4,115,200

0.10%

160,000

DEUTSCHE BANK AG\

$3,852,958

0.10%

149,804

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS INVESTMENT MANAGEMENT AMERICAS, INC	29	$745	0.0%	Defined
DWS Investments UK Ltd	149,775	$3,852,213	100.0%	Defined

GREAT LAKES ADVISORS, LLC

$3,730,557

0.09%

145,045

VANGUARD ASSET MANAGEMENT, Ltd

$3,630,455

0.09%

141,153

Man Group plc

$3,576,751

0.09%

139,065

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AHL Partners LLP	139,065	$3,576,751	100.0%	Defined

Hudson Bay Capital Management LP

$3,343,600

0.08%

130,000

Odyssean, LLC

$3,216,594

0.08%

125,062

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$3,170,195

0.08%

123,258

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	123,258	$3,170,195	100.0%	Other

MANUFACTURERS LIFE INSURANCE COMPANY, THE

$3,018,190

0.07%

117,348

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MANULIFE FINANCIAL CORP joint	117,348	$3,018,190	100.0%	Defined

Zurcher Kantonalbank (Zurich Cantonalbank)

$2,977,733

0.07%

115,775

B. Metzler seel. Sohn & Co. AG

$2,888,356

0.07%

112,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Metzler Asset Management GmbH	112,300	$2,888,356	100.0%	Defined

Legal & General Group Plc

$2,879,430

0.07%

111,953

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Legal & General Investment Management America Inc	14,281	$367,307	12.8%	Defined
Legal & General Investment Management Ltd joint	97,672	$2,512,123	87.2%	Defined

Integrated Wealth Concepts LLC

$2,629,638

0.07%

102,241

PFM Health Sciences, LP

$2,596,845

0.06%

100,966

Ghisallo Capital Management LLC

$2,572,000

0.06%

100,000

Integral Health Asset Management, LLC

$2,572,000

0.06%

100,000

Lumbard & Kellner, LLC

$2,527,813

0.06%

98,282

Rafferty Asset Management, LLC

$2,477,916

0.06%

96,342

D.A. DAVIDSON & CO.

$2,256,698

0.06%

87,741

Russell Investments Group, Ltd.

$2,212,741

0.05%

86,032

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	73,656	$1,894,431	85.6%	Defined
Russell Investments Capital, LLC	3,284	$84,464	3.8%	Defined
Russell Investments Limited	9,092	$233,846	10.6%	Defined

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$2,206,776

0.05%

85,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	85,800	$2,206,776	100.0%	Other

MetLife Investment Management, LLC

$2,202,172

0.05%

85,621

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
METLIFE INC	85,621	$2,202,172	100.0%	Defined

BARCLAYS PLC

$2,183,421

0.05%

84,892

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS BANK PLC	79,676	$2,049,266	93.9%	Defined
BARCLAYS CAPITAL INC.	5,216	$134,155	6.1%	Defined

STATE OF WISCONSIN INVESTMENT BOARD

$2,177,249

0.05%

84,652

Creative Planning

$2,177,043

0.05%

84,644

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CREATIVE PLANNING TRUST Co LLC	317	$8,153	0.4%	Defined
Held directly	84,327	$2,168,890	99.6%	Sole

AMERIPRISE FINANCIAL INC

$2,125,758

0.05%

82,650

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Columbia Management Investment Advisers, LLC	81,450	$2,094,894	98.5%	Defined
Ameriprise Financial Services, LLC	1,200	$30,864	1.5%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Global X Management CO LLC joint	67,745	$1,742,401	85.8%	Defined
Global X Management (AUS) Ltd joint	11,192	$287,858	14.2%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	77,300	$1,988,156	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	19,519	$502,028	29.1%	Defined
Held directly	47,452	$1,220,465	70.9%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JANUS HENDERSON INVESTORS UK Ltd	60,028	$1,543,920	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SEI INVESTMENTS MANAGEMENT CORP	29,434	$757,042	49.9%	Sole
SEI TRUST CO	29,555	$760,154	50.1%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	58,800	$1,512,336	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PGIM Quantitative Solutions LLC	47,035	$1,209,740	80.9%	Defined
Prudential Trust Co	11,100	$285,492	19.1%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FIDUCIARY TRUST CO INTERNATIONAL	105	$2,700	0.2%	Defined
FIDUCIARY TRUST INTERNATIONAL LLC	2,556	$65,740	4.5%	Defined
FRANKLIN ADVISERS INC	54,001	$1,388,905	95.3%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ADVISOR PARTNERS II, LLC	53,603	$1,378,669	99.2%	Defined
Held directly	411	$10,570	0.8%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wellington Management Company LLP	26,602	$684,203	50.6%	Defined
Wellington Managment Canada LLC	1,485	$38,194	2.8%	Defined
Wellington Trust Company, NA joint	21,132	$543,515	40.2%	Defined
Wellington Management Europe GmbH	3,399	$87,422	6.5%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
EVOKE WEALTH, LLC	1,095	$28,163	2.2%	Defined
Held directly	48,065	$1,236,231	97.8%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Voya Investment Management Co. LLC joint	45,823	$1,178,567	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	45,200	$1,162,544	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RAYMOND JAMES & ASSOCIATES	2,323	$59,747	5.3%	Defined
Raymond James Financial Services Advisors, Inc.	22,928	$589,708	52.4%	Defined
ClariVest Asset Management LLC joint	18,493	$475,639	42.3%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Capital	43,387	$1,115,913	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nomura Asset Management Europe KVG mbH	36,732	$944,747	100.0%	Sole
Held directly	0	$0	0.0%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jefferies Financial Services, Inc.	34,425	$885,411	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Thrivent Asset Management, LLC	12,633	$324,920	38.8%	Defined
Held directly	19,922	$512,393	61.2%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Capstone Investment Advisors (UK), LLP	20,964	$539,194	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ALLSTATE INVESTMENTS LLC	19,313	$496,730	100.0%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Manager 1	18,556	$477,260	100.0%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Bellevue Asset Management AG	17,766	$456,941	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
OSAIC WEALTH, INC.	1,103	$28,369	6.5%	Defined
CW Advisors, LLC	15,913	$409,282	93.5%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Strive Asset Management, LLC	4,791	$123,224	33.2%	Other
Held directly	9,637	$247,863	66.8%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC CMA LTD.	4,476	$115,122	32.0%	Defined
RBC Capital Markets, LLC	9,251	$237,935	66.2%	Defined
RBC Trust Co (Delaware) Ltd	92	$2,366	0.7%	Defined
Held directly	155	$3,986	1.1%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GUGGENHEIM FUNDS DISTRIBUTORS, LLC	11,159	$287,009	81.8%	Defined
SECURITY INVESTORS LLC	1,415	$36,393	10.4%	Defined
Guggenheim Partners Investment Management, LLC joint	1,062	$27,314	7.8%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
EATON VANCE MANAGEMENT	13,351	$343,387	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Lynx1 Capital Advisors LLC	11,658	$299,843	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Latour Trading LLC (Latour)	11,393	$293,027	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PNC Bank, National Association	8,520	$219,133	93.4%	Defined
PNC Wealth Management LLC	602	$15,483	6.6%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ROCKEFELLER & CO. LLC	450	$11,574	5.1%	Defined
ROCKEFELLER TRUST COMPANY, N.A.	1,788	$45,987	20.1%	Defined
ROCKEFELLER FINANCIAL LLC	6,656	$171,192	74.8%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DNB FUND	8,581	$220,703	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
First Sentier Investors RQI Pty Ltd	8,494	$218,465	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CIBC WORLD MARKETS CORP	8,122	$208,897	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Acadian Inc	6,476	$166,562	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Intesa Sanpaolo S.p.A.	5,045	$129,757	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
KBC Bank NV joint	4,943	$127,133	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fifth Third Bank, National Association	3,019	$77,648	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nykredit Bank A/S	1,488	$38,271	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MITSUBISHI UFJ FINANCIAL GROUP INC	1,001	$25,745	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
US BANK NATIONAL ASSOCIATION	950	$24,434	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Optiver VOF	776	$19,958	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BMSS Wesson Wealth Solutions, LLC	20	$513	9.4%	Sole
Held directly	193	$4,962	90.6%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Edward D. Jones & Co., L.P.	104	$2,674	100.0%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JOHNSON BANK	81	$2,083	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
TORONTO DOMINION BANK	71	$1,826	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Deka Vermoegensmanagement GmbH	59,800	$1,130	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Frost Investment Services, LLC	10	$257	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DIMENSIONAL FUND ADVISORS LP	7	$180	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Schroder Investment Management Limited	285,289	$5,477,548	99.8%	Sole
Schroder Investment Management North America Inc.	531	$10,195	0.2%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JANUS HENDERSON INVESTORS UK Ltd	60,028	$1,152,537	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Virtu Americas LLC	43,362	$832,550	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Amundi Asset Management	18,604	$357,196	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AMERICAN CENTURY INVESTMENT MANAGEMENT INC	218	$4,185	25.7%	Sole
Fidelity Institutional Asset Management Trust Co	16	$307	1.9%	Sole
SEI INVESTMENTS MANAGEMENT CORP	529	$10,156	62.4%	Sole
Held directly	85	$1,632	10.0%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Manager 1 joint	512	$9,830	100.0%	Sole

Key facts CIK 1714899 CUSIP 24823R105 13F (30d) 262 filings 255 filers Visit website Investor relations