IDYA · IDEAYA Biosciences, Inc. · Holdings

$35.36 +1.55 (+4.58%)

Russell 2000 member Rebalance outlook locked

Market Cap

$3.26B

96.49M

Volume · Oct 20 953.3K Avg daily vol (3M) 788.92K

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP → See every holder of IDYA: 13F, 13D and 13G, insiders and funds →

Institutional holdings are being reconciled with SEC filings. Holder totals and changes may be incomplete until reconciliation finishes.

The Sep 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out. Each fund's Change is measured against its own previous reported quarter, shown in the Reported column. Pick a completed quarter in the Quarter selector below to put every fund on one quarter and see the stock-wide activity breakdown.

Quarter:

Holders: 289

Total Value: $3,837,041,687

Total Shares: 102,992,687

Showing 1–100 of 296 holdings by value · page 1 of 3

Institutional Ownership Trend

27 quarters

Holder Concentration

Across 287 13F filers

Top Holder

13.7%

of institutional value

Top 5

40.8%

of institutional value

Top 10

57.4%

of institutional value

HHI

481

Broadly held

Who Holds IDYA

Last 8 quarters through Sep 30, 2026 (filing window open)

Each kind of 13F filer's share of the common shares 13F filers report. Holder type comes from regulatory records, never the filer's name; style, turnover and horizon are measured from each filer's own 13F book. The quarter selector does not change this card.

Jun 30, 2026, the newest closed quarter: 285 filers, like-for-like change +7.9%; actively managed books +8.7%; index-like books +6.0%.

Holder type	Share	Filers	Change	New	Exited
Registered adviser	36.2%	144	+19.9%	41	21
Exempt adviser	0.8%	2	+19.2%	1	2
Adviser	8.3%	10	-9.9%	2	1
Bank	8.0%	17	+12.1%	0	0
Insurer	0.0%	1	-0.7%	0	0
Broker-dealer	0.0%	3	+56.4%	2	0
Registered fund	0.3%	1	+10.0%	0	0
Benefit plan	0.2%	6	+10.4%	1	0
Non-US	3.2%	9	-21.8%	1	0
Holding company	26.2%	8	+3.6%	0	1
Unknown	16.8%	84	+7.7%	15	9

Style	Share	Filers	Change	New	Exited
Index-like	27.1%	34	+6.0%	0	1
Systematic-like	2.3%	25	-18.7%	12	8
Concentrated	7.9%	39	+25.2%	15	5
Diversified active	62.7%	187	+8.2%	36	20
Not measured	0.0%	0	—	0	0
Unknown	0.0%	0	—	0	0

Turnover	Share	Filers	Change	New	Exited
Low turnover	60.1%	146	+7.6%	15	10
Medium turnover	17.4%	71	+5.9%	18	10
High turnover	6.8%	42	+4.4%	25	13
Unknown	15.7%	26	+13.4%	5	1
Not measured	0.0%	0	—	0	0

Holding horizon	Share	Filers	Change	New	Exited
Short horizon	17.1%	40	+19.0%	17	7
Medium horizon	14.5%	48	+2.5%	14	5
Long horizon	62.3%	177	+5.5%	25	11
Unknown	6.2%	20	+19.7%	7	11
Not measured	0.0%	0	—	0	0

13F book size	Share	Filers	Change	New	Exited
Under $1B	3.2%	60	0.0%	23	12
$1B to $10B	10.8%	77	+21.6%	24	14
$10B to $100B	18.1%	79	-7.3%	11	5
$100B or more	67.9%	69	+11.2%	5	3
Not measured	0.0%	0	—	0	0

Client base	Share	Filers	Change	New	Exited
Individuals and high net worth	0.9%	59	+11.5%	16	6
Pooled investment vehicles	19.3%	38	+21.0%	19	11
Registered funds and BDCs	13.0%	18	+18.0%	2	1
Pension and profit sharing plans	0.0%	1	-16.6%	0	0
Insurance companies	0.2%	4	+113.1%	0	0
Governments and sovereign funds	0.2%	3	-83.0%	1	2
Corporations	0.0%	1	0.0%	0	0
Other investment advisers	0.0%	4	+10.4%	0	0
Other	0.1%	2	+638.3%	1	0
Diversified	2.3%	12	+110.6%	2	1
Unknown	63.9%	143	+2.1%	22	13

Private funds	Share	Filers	Change	New	Exited
Hedge funds	16.6%	45	+22.0%	19	13
Private equity funds	0.3%	7	-2.5%	1	1
Venture capital funds	3.0%	3	-11.2%	1	0
Real estate funds	0.0%	3	+25.9%	1	1
Securitized asset funds	0.1%	1	-18.2%	0	0
Other private funds	5.4%	10	+26.5%	0	0
Mixed private funds	1.9%	4	+484.9%	1	0
Private funds, type not stated	0.1%	2	+4.7%	1	2
No private funds	9.5%	70	+10.4%	18	6
Unknown	63.1%	140	+1.9%	21	11

Location	Share	Filers	Change	New	Exited
United States	89.3%	233	+9.2%	55	29
Outside the US	10.7%	52	-1.3%	8	5

The Sep 30, 2026 filing window is still open, so its bar carries the Jun 30, 2026 positions of filers that have not filed yet.

How the mix is measured

Shares are 13F common shares restated to today's split basis; options and principal amounts are left out. The change compares only filers with a 13F in both quarters and keeps each filer in its bucket of the later quarter on both sides; a filer that continues under a new CIK is compared through its successor. Holder type comes from each filer's current regulatory profile; client base and private funds come from the Form ADV roster current at each quarter end (rosters from December 2019, so an earlier quarter reads Unknown). Style, turnover, horizon and book size are measured from each filer's 13F book in the newest measured quarter, and Not measured means none was. Actively managed books are those measured systematic-like, concentrated or diversified active.

Excluded 3 holders with no observed 2026-03-31 13F and 1 holder with no observed 2026-06-30 13F. Compared across CIK changes: JANUS HENDERSON GROUP PLC continues as Jupiter Topco LLC.

Conviction and Crowding

285 13F filers, quarter ended Jun 30, 2026

Measured across every 13F filer's common-share book once the quarter's filing window closed. Crowding counts filers with high turnover or that advise private funds on Form ADV.

Conviction holders

1.75% of filers hold it in their top 10

Mar 31, 2026: 3

Holders above 5%

median weight 0.003%

Mar 31, 2026: 2

Crowding

—

holders exceed shares outstanding: 13F filers report more shares than the cover-page count, which predates an issuance, is misstated, or misses shares lent and reported twice

Private-fund advisers

—

of shares outstanding

Institutional ownership

—

holders exceed shares outstanding: 13F filers report more shares than the cover-page count, which predates an issuance, is misstated, or misses shares lent and reported twice

Top 10 holders

57.8%

of 13F shares, Herfindahl 0.049

Active holders

+8.7%

like-for-like share change of active filers

5% stakes on record

0 13D, 9 13G (7 institutional, 1 passive, 0 exempt)

How long holders have held it value-weighted 14.2 quarters

Under 1 year 22.0% 1 to 3 years 17.9% 3 years or more 60.2% Since coverage start 0.000%

Managers in the top fifth by current three-year FundScore alpha were net buyers of $1,530,572 (1 buying, 0 selling).

Estimated Holder Cost Basis

Quarter ended Jun 30, 2026, on that quarter's share basis

Estimated, never filed: each 13F buy is costed at its quarter's average traded price and each sale keeps the average cost, so this is what holders paid on average if they traded evenly through each quarter.

Estimated avg cost

$29.59

estimated per share

Mar 31, 2026: $29.30

Quarter-end price

$37.25

implied by 13F values

Estimated gain or loss

+25.9%

price against the estimated cost

Estimated at a loss

17.6%

of costed 13F value

Estimated cost covers 78.7% of the 13F shares; positions already held when a filer's 13F history starts, or bought in a quarter without a trusted average price, have no estimate.

Shared Holders

Companies IDYA's active holders also own, quarter ended Jun 30, 2026

#	Company	Shared holders	Similarity
1	STOK Stoke Therapeutics, Inc.	9	0.347
2	TNGX Tango Therapeutics, Inc.	11	0.307
3	GPCR Structure Therapeutics Inc.	11	0.300
4	WVE Wave Life Sciences, Inc.	8	0.297
5	SVRA Savara Inc	9	0.296
6	IRON Disc Medicine, Inc.	9	0.287
7	DNTH Dianthus Therapeutics, Inc. /DE/	11	0.286
8	XENE Xenon Pharmaceuticals Inc.	11	0.278
9	RCUS Arcus Biosciences, Inc.	7	0.276
10	PMVP PMV Pharmaceuticals, Inc.	5	0.273

Shareholder Targets

13F filers that own its peers but not IDYA, quarter ended Jun 30, 2026

Found through its holder-overlap peers: STOK, TNGX, GPCR, WVE, SVRA, IRON, DNTH, XENE, RCUS, PMVP, DSGN, NGNE, COGT, MLYS, SKYE, LRMR, CLDX, IMNM, PRAX, MDGL. 618 filers in all.

#	Filer	In peers	Of book	Largest peers
1	Avoro Capital Advisors LLC Registered adviser, Concentrated	$1,684,991,409 3 held	15.1%	MDGL, GPCR, XENE
2	T. Rowe Price Investment Management, Inc. Adviser, Diversified active	$1,085,701,461 7 held	0.710%	IMNM, DNTH, XENE
3	GILEAD SCIENCES, INC. Unknown, Concentrated	$968,825,350 1 held	58.7%	RCUS
4	Driehaus Capital Management LLC Registered adviser, Diversified active	$955,065,354 11 held	5.55%	PRAX, XENE, IMNM
5	Polar Capital Holdings Plc Registered adviser, Diversified active	$895,589,944 9 held	2.53%	XENE, MDGL, COGT
6	TCG Crossover Management, LLC Unknown, Diversified active	$809,477,291 5 held	19.5%	TNGX, COGT, DNTH
7	PERCEPTIVE ADVISORS LLC Registered adviser, Diversified active	$791,878,645 3 held	12.8%	PRAX, TNGX, COGT
8	PAULSON & CO. INC. Adviser, Concentrated	$719,523,739 1 held	27.9%	MDGL
9	Siren, L.L.C. Unknown, Diversified active	$604,019,811 8 held	12.3%	TNGX, XENE, RCUS
10	Deep Track Capital, LP Adviser, Diversified active	$572,457,472 4 held	8.72%	GPCR, TNGX, CLDX

Fund Ownership of IDYA by Fund Type

Registered funds' Form N-PORT reports for the quarter ended Jun 30, 2026

Index funds and index ETFs hold 15.85% of shares outstanding.

Fund type	Of shares outstanding	Change	Shares	Funds
Index funds	3.14%	+0.33 pp	3,029,644	63
Index ETFs	12.71%	+1.54 pp	12,264,398	48
Active ETFs	0.80%	+0.04 pp	775,865	15
Active funds	24.26%	+5.21 pp	23,412,670	117
Unclassified	0.23%	+0.23 pp	220,878	9
All registered funds	41.15%	+7.35 pp	39,703,455	252

How fund types are measured

Each fund series counts once, with its latest Form N-PORT report dated inside the quarter; only long share positions count, restated to today's split basis. The fund type is the series' latest Form N-CEN answer on or before the quarter end (the index-fund box and the exchange-traded flag), never its name. Unclassified funds have no usable N-CEN; unit investment trusts are among them, so index ownership is a floor. Funds sit inside their advisers' 13F reports, so these shares overlap the 13F figures and are never added to them.

Holder type: Registered adviser 146 Exempt adviser 2 Adviser 10 Bank 17 Insurer 1 Broker-dealer 3 Registered fund 1 Benefit plan 6 Non-US 9 Holding company 8 Unknown 86

Showing 100 of 296

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

FMR LLC

$525,858,493

13.70%

14,109,431

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	7,826,749	$291,702,935	55.5%	Defined
FIDELITY MANAGEMENT TRUST CO	6,278,204	$233,988,663	44.5%	Defined
STRATEGIC ADVISERS LLC	4,478	$166,895	0.0%	Defined

BlackRock, Inc.

$331,451,793

8.64%

8,893,260

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	180,652	$6,732,900	2.0%	Sole
BlackRock Investment Management (Australia) Ltd	106	$3,950	0.0%	Sole
BlackRock Asset Management Canada Ltd	22,041	$821,468	0.2%	Sole
BlackRock Investment Management, LLC	289,656	$10,795,479	3.3%	Sole
BLACKROCK ADVISORS LLC	503,443	$18,763,320	5.7%	Sole
BlackRock Fund Advisors	4,024,155	$149,980,256	45.2%	Sole
BlackRock Institutional Trust Company, N.A.	3,117,348	$116,183,559	35.1%	Sole
BlackRock Japan Co. Ltd	6,246	$232,788	0.1%	Sole
BlackRock Fund Managers Ltd.	14,301	$532,998	0.2%	Sole
BlackRock Investment Management (UK) Ltd.	83,395	$3,108,131	0.9%	Sole
BlackRock Asset Management Ireland Ltd	332,267	$12,383,591	3.7%	Sole
BlackRock (Luxembourg) S.A.	2,724	$101,523	0.0%	Sole
BlackRock Life Ltd	451	$16,808	0.0%	Sole
BlackRock Asset Management Schweiz AG	12,338	$459,837	0.1%	Sole
Aperio Group, LLC	304,137	$11,335,185	3.4%	Sole

Jupiter Topco LLC

$319,772,164

8.33%

8,579,881

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JANUS HENDERSON INVESTORS UK Ltd	235,028	$8,759,493	2.7%	Defined
JANUS HENDERSON INVESTORS US LLC	8,325,400	$310,287,658	97.0%	Defined
Held directly	19,453	$725,013	0.2%	Defined

Capital Research Global Investors

$199,197,006

5.19%

5,344,701

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CAPITAL GROUP COMPANIES INC joint	5,344,701	$199,197,006	100.0%	Defined

BAKER BROS. ADVISORS LP

$186,723,818

4.87%

5,010,030

STATE STREET CORP

$169,537,912

4.42%

4,548,911

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	4,548,911	$169,537,912	100.0%	Defined

VANGUARD CAPITAL MANAGEMENT LLC

$154,023,716

4.01%

4,132,646

Logos Global Management LP

$111,810,000

2.91%

3,000,000

ADAGE CAPITAL PARTNERS GP, L.L.C.

$101,202,622

2.64%

2,715,391

DEERFIELD MANAGEMENT COMPANY, L.P.

$101,169,526

2.64%

2,714,503

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Deerfield UGP, LLC	2,714,503	$101,169,526	100.0%	Defined

GEODE CAPITAL MANAGEMENT, LLC

$90,402,186

2.36%

2,425,602

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	334,419	$12,463,796	13.8%	Defined
Held directly	2,091,183	$77,938,390	86.2%	Defined

PRICE T ROWE ASSOCIATES INC /MD/

$82,271,697

2.14%

2,207,451

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	141,014	$5,255,591	6.4%	Defined
Held directly	2,066,437	$77,016,106	93.6%	Sole

MORGAN STANLEY

$71,986,667

1.88%

1,931,491

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	975	$36,338	0.1%	Defined
MORGAN STANLEY & CO. LLC	30,681	$1,143,480	1.6%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	1,506,835	$56,159,740	78.0%	Defined
MORGAN STANLEY SMITH BARNEY LLC	6,753	$251,684	0.3%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	386,247	$14,395,425	20.0%	Defined

DIMENSIONAL FUND ADVISORS LP

$61,915,940

1.61%

1,661,281

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dimensional Fund Advisors Ltd.	12,133	$452,196	0.7%	Defined
DFA Australia Ltd.	13,082	$487,566	0.8%	Defined
Dimensional Fund Advisors Pte. Ltd.	796	$29,666	0.0%	Defined
Dimensional Ireland Ltd	76,728	$2,859,652	4.6%	Defined
Held directly	1,558,542	$58,086,860	93.8%	Sole

ALLIANCEBERNSTEIN L.P.

$60,657,707

1.58%

1,627,521

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	1,627,521	$60,657,707	100.0%	Defined

Fiera Capital Corp

$53,888,133

1.40%

1,445,885

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fiera Capital Inc.	1,415,173	$52,743,497	97.9%	Other
Held directly	30,712	$1,144,636	2.1%	Sole

FEDERATED HERMES, INC.

$53,356,850

1.39%

1,431,630

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FEDERATED GLOBAL INVESTMENT MANAGEMENT CORP	1,431,630	$53,356,850	100.0%	Defined

GSK plc

$49,693,320

1.30%

1,333,333

BNP PARIBAS ASSET MANAGEMENT Holding S.A.

$47,328,761

1.23%

1,269,889

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BNP PARIBAS ASSET MANAGEMENT Europe	1,025	$38,201	0.1%	Defined
BNP Paribas Asset Management USA, Inc.	994,395	$37,061,101	78.3%	Defined
AXA INVESTMENT MANAGERS UK LIMITED	274,469	$10,229,459	21.6%	Defined

GOLDMAN SACHS GROUP INC

$45,902,252

1.20%

1,231,614

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	544,503	$20,293,626	44.2%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	676,160	$25,200,483	54.9%	Defined
Goldman Sachs Trust Company, N.A. joint	10,951	$408,143	0.9%	Other

Candriam S.C.A.

$40,710,058

1.06%

1,092,301

BANK OF AMERICA CORP /DE/

$38,244,347

1.00%

1,026,143

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	360,087	$13,420,442	35.1%	Defined
BOFA SECURITIES, INC.	339,033	$12,635,759	33.0%	Defined
MANAGED ACCOUNT ADVISORS LLC joint	327,023	$12,188,146	31.9%	Defined

Sofinnova Investments, Inc.

$34,479,185

0.90%

925,119

ARROWSTREET CAPITAL, LIMITED PARTNERSHIP

$33,230,230

0.87%

891,608

Fisher Asset Management, LLC

$31,728,174

0.83%

851,306

VANGUARD PORTFOLIO MANAGEMENT LLC

$30,621,479

0.80%

821,612

NORTHERN TRUST CORP

$29,969,475

0.78%

804,118

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	746,452	$27,820,265	92.8%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	44,657	$1,664,365	5.6%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	13,009	$484,845	1.6%	Other

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$28,134,675

0.73%

754,888

Pictet Asset Management Holding SA

$26,561,359

0.69%

712,674

UBS Group AG

$24,475,991

0.64%

656,721

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	81,912	$3,052,860	12.5%	Defined
UBS AG	561,509	$20,927,440	85.5%	Defined
UBS Switzerland AG	13,300	$495,691	2.0%	Defined

Nuveen, LLC

$23,862,377

0.62%

640,257

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	11,135	$415,001	1.7%	Defined
TIAA CREF INVESTMENT MANAGEMENT LLC joint	150,022	$5,591,319	23.4%	Defined
TEACHERS ADVISORS, LLC joint	479,100	$17,856,057	74.8%	Defined

Redmile Group, LLC

$23,860,328

0.62%

640,202

VANGUARD FIDUCIARY TRUST CO

$23,145,601

0.60%

621,025

Qube Research & Technologies Ltd

$22,081,468

0.58%

592,473

Aberdeen Group plc

$20,906,010

0.54%

560,934

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
abrdn Inc.	560,934	$20,906,010	100.0%	Defined

NEW YORK STATE COMMON RETIREMENT FUND

$18,709,167

0.49%

501,990

DAFNA Capital Management LLC

$18,532,134

0.48%

497,240

Sio Capital Management, LLC

$17,903,874

0.47%

480,383

TANG CAPITAL MANAGEMENT LLC

$16,771,500

0.44%

450,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
TANG KEVIN	450,000	$16,771,500	100.0%	Other

Affinity Asset Advisors, LLC

$14,908,000

0.39%

400,000

Walleye Capital LLC

$14,393,040

0.38%

386,183

RTW INVESTMENTS, LP

$13,803,689

0.36%

370,370

Rhenman & Partners Asset Management AB

$12,813,426

0.33%

343,800

BIT Capital GmbH

$11,603,380

0.30%

311,333

GENERAL AMERICAN INVESTORS CO INC

$11,488,104

0.30%

308,240

FIRST TRUST ADVISORS LP

$11,431,789

0.30%

306,729

CITADEL ADVISORS LLC

$11,197,324

0.29%

300,438

WELLS FARGO & COMPANY/MN

$11,100,793

0.29%

297,848

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	70,890	$2,642,070	23.8%	Defined
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC	34,869	$1,299,567	11.7%	Defined
WELLS FARGO CLEARING SERVICES, LLC	191,909	$7,152,448	64.4%	Defined
WELLS FARGO INVESTMENT INSTITUTE, INC.	180	$6,708	0.1%	Defined

Balyasny Asset Management L.P.

$11,090,247

0.29%

297,565

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$10,267,885

0.27%

275,500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	275,500	$10,267,885	100.0%	Other

JPMORGAN CHASE & CO

$9,969,499

0.26%

267,494

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
J.P. Morgan Trust Co of Delaware	849	$31,642	0.3%	Other
JPMorgan Chase Bank, N.A.	44,531	$1,659,670	16.6%	Defined
J.P. Morgan Investment Management Inc.	174,364	$6,498,546	65.2%	Defined
J.P. Morgan Securities LLC	333	$12,410	0.1%	Defined
55I, LLC	24	$894	0.0%	Other
J.P. MORGAN MANSART MANAGEMENT Ltd	47,393	$1,766,337	17.7%	Defined

Ensign Peak Advisors, Inc

$9,957,873

0.26%

267,182

Bank of New York Mellon Corp

$9,884,112

0.26%

265,203

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Investments Corporation joint	101,844	$3,795,725	38.4%	Defined
The Bank of New York Mellon	154,683	$5,765,035	58.3%	Defined
BNY Mellon, NA joint	5,731	$213,593	2.2%	Defined
BNY Mellon Advisors, Inc.	2,943	$109,685	1.1%	Defined
Held directly	2	$74	0.0%	Defined

JENNISON ASSOCIATES LLC

$9,263,793

0.24%

248,559

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Prudential Financial Inc	248,559	$9,263,793	100.0%	Defined

Man Group plc

$9,149,486

0.24%

245,492

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AHL Partners LLP	140	$5,217	0.1%	Defined
Numeric Investors LLC	245,352	$9,144,269	99.9%	Defined

FRANKLIN RESOURCES INC

$8,579,888

0.22%

230,209

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FIDUCIARY TRUST INTERNATIONAL LLC	1,454	$54,190	0.6%	Defined
FRANKLIN ADVISERS INC	228,755	$8,525,698	99.4%	Defined

ENVESTNET ASSET MANAGEMENT INC

$8,352,542

0.22%

224,109

AMERICAN CENTURY COMPANIES INC

$7,804,114

0.20%

209,394

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AMERICAN CENTURY INVESTMENT MANAGEMENT INC	209,394	$7,804,114	100.0%	Defined

SummitTX Capital, L.P.

$7,635,579

0.20%

204,872

Susquehanna Portfolio Strategies, LLC

$7,627,640

0.20%

204,659

Woodline Partners LP

$7,516,129

0.20%

201,667

Burkehill Global Management, LP

$7,454,000

0.19%

200,000

SPHERA FUNDS MANAGEMENT LTD.

$7,320,126

0.19%

196,408

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Sphera Global Healthcare Management LP joint	196,408	$7,320,126	100.0%	Defined

SCHRODER INVESTMENT MANAGEMENT GROUP

$6,970,123

0.18%

187,017

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Schroder Investment Management Limited	186,741	$6,959,837	99.9%	Sole
Schroder Investment Management North America Inc.	276	$10,286	0.1%	Sole

Verition Fund Management LLC

$6,859,692

0.18%

184,054

WCM INVESTMENT MANAGEMENT, LLC

$6,476,966

0.17%

173,785

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$6,365,716

0.17%

170,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	170,800	$6,365,716	100.0%	Other

Swiss National Bank

$5,911,022

0.15%

158,600

ROYAL BANK OF CANADA

$5,894,322

0.15%

158,152

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC CMA LTD.	2,524	$94,069	1.6%	Defined
RBC Capital Markets, LLC	151,682	$5,653,188	95.9%	Defined
RBC Dominion Securities Inc.	1,913	$71,297	1.2%	Defined
RBC Private Counsel (USA) Inc.	1,345	$50,128	0.9%	Defined
RBC Trust Co (Delaware) Ltd	288	$10,733	0.2%	Defined
RBC Rochdale, LLC	288	$10,733	0.2%	Defined
Held directly	112	$4,174	0.1%	Sole

CONGRESS ASSET MANAGEMENT CO

$5,674,480

0.15%

147,696

VICTORY CAPITAL MANAGEMENT INC

$5,641,932

0.15%

151,380

Creative Planning

$5,612,190

0.15%

150,582

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CREATIVE PLANNING TRUST Co LLC	2,503	$93,286	1.7%	Defined
Held directly	148,079	$5,518,904	98.3%	Sole

Rheos Capital Works Inc.

$5,590,500

0.15%

150,000

Tema ETFs LLC

$5,577,854

0.15%

145,181

Invesco Ltd.

$5,412,347

0.14%

145,220

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	12,380	$461,401	8.5%	Defined
Invesco Trust Co joint	33,586	$1,251,750	23.1%	Defined
Invesco Capital Management LLC	99,254	$3,699,196	68.3%	Defined

UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC

$5,340,226

0.14%

143,285

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Group AG	2,185	$81,434	1.5%	Defined
UBS Asset Management Switzerland AG	111,353	$4,150,125	77.7%	Defined
UBS Asset Management (UK) Ltd.	17,627	$656,956	12.3%	Defined
Held directly	12,120	$451,711	8.5%	Defined

PLATINUM INVESTMENT MANAGEMENT LTD

$5,169,647

0.13%

138,708

FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A.

$5,155,782

0.13%

138,336

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Intesa Sanpaolo S.p.A.	138,336	$5,155,782	100.0%	Defined

Tidal Investments LLC

$5,063,017

0.13%

135,847

VOYA INVESTMENT MANAGEMENT LLC

$4,625,877

0.12%

124,118

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Voya Investment Management Co. LLC joint	124,118	$4,625,877	100.0%	Defined

TD Asset Management Inc

$4,422,830

0.12%

118,670

Universal- Beteiligungs- und Servicegesellschaft mbH

$4,204,056

0.11%

112,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Universal-Investment-Gesellschaft mbH	112,800	$4,204,056	100.0%	Defined

RHUMBLINE ADVISERS

$4,165,444

0.11%

111,764

CITIGROUP INC

$4,135,851

0.11%

110,970

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	110,970	$4,135,851	100.0%	Defined

MANUFACTURERS LIFE INSURANCE COMPANY, THE

$4,009,692

0.10%

107,585

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MANULIFE FINANCIAL CORP joint	107,585	$4,009,692	100.0%	Defined

Odyssean, LLC

$3,823,231

0.10%

102,582

Integral Health Asset Management, LLC

$3,727,000

0.10%

100,000

Atle Fund Management AB

$3,521,195

0.09%

94,478

CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM

$3,500,994

0.09%

93,936

DEUTSCHE BANK AG\

$3,497,564

0.09%

93,844

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Deutsche Bank Trust Co Americas	4,479	$166,932	4.8%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC	154	$5,739	0.2%	Defined
DWS Investments UK Ltd	86,216	$3,213,270	91.9%	Defined
DWS International GmbH	2,995	$111,623	3.2%	Defined

Connor, Clark & Lunn Investment Management Ltd.

$3,359,331

0.09%

90,135

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Manager 1	89,964	$3,352,958	99.8%	Sole
Held directly	171	$6,373	0.2%	Sole

ALPS ADVISORS INC

$3,308,420

0.09%

88,769

GREAT LAKES ADVISORS, LLC

$3,270,330

0.09%

87,747

JANE STREET GROUP, LLC

$3,018,870

0.08%

81,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	81,000	$3,018,870	100.0%	Defined

Legal & General Group Plc

$2,998,781

0.08%

80,461

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Legal & General Investment Management America Inc	8,142	$303,452	10.1%	Defined
Legal & General Investment Management Ltd joint	72,319	$2,695,329	89.9%	Defined

CITIGROUP INC

$2,985,327

0.08%

80,100

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	80,100	$2,985,327	100.0%	Defined

KVP Capital Advisors, LP

$2,970,419

0.08%

79,700

MARTINGALE ASSET MANAGEMENT L P

$2,622,317

0.07%

70,360

SEI INVESTMENTS CO

$2,571,107

0.07%

68,986

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SEI INVESTMENTS MANAGEMENT CORP	22,587	$841,817	32.7%	Sole
SEI TRUST CO	46,399	$1,729,290	67.3%	Sole

AQR CAPITAL MANAGEMENT LLC

$2,533,462

0.07%

67,976

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RF&L WEALTH MANAGEMENT, LLC	9	$335	0.0%	Other
Compound Planning, Inc.	16	$596	0.0%	Other
Arax Advisory Partners	288	$10,733	0.4%	Other
HALBERT HARGROVE GLOBAL ADVISORS, LLC	218	$8,124	0.3%	Other
Stokes Family Office, LLC	40	$1,490	0.1%	Other
Held directly	67,405	$2,512,184	99.2%	Defined

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Key facts CIK 1676725 CUSIP 45166A102 13F (30d) 22 filings 22 filers Visit website Investor relations