WVE · Wave Life Sciences, Inc. · Holdings

$3.50 +0.03 (+0.72%)

Russell 2000 member Rebalance outlook locked

Market Cap

$683.76M

197.05M

Volume · Oct 9 964.48K Avg daily vol (3M) 3.1M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP →

Some SEC filings for this period have not finished importing. Holder totals and changes may be incomplete; these filings remain queued for recovery.

The Sep 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out. Each fund's Change is measured against its own previous reported quarter, shown in the Reported column. Pick a completed quarter in the Quarter selector below to put every fund on one quarter and see the stock-wide activity breakdown.

Quarter:

Holders: 240

Total Value: $1,064,532,743

Total Shares: 183,226,219

Showing 1–100 of 250 holdings by value · page 1 of 3

Institutional Ownership Trend

27 quarters

Superinvestors Holding WVE

All superinvestors →

Stanley Druckenmiller $1,005,130

Holder Concentration

Across 242 13F filers

Top Holder

14.7%

of institutional value

Top 5

43.7%

of institutional value

Top 10

57.3%

of institutional value

HHI

543

Broadly held

Showing 100 of 250

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

RA CAPITAL MANAGEMENT, L.P.

$156,727,684

14.72%

26,975,505

BlackRock, Inc.

$111,566,291

10.48%

19,202,461

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	953,490	$5,539,776	5.0%	Sole
BlackRock Investment Management (Australia) Ltd	446	$2,591	0.0%	Sole
BlackRock Asset Management Canada Ltd	1,117	$6,489	0.0%	Sole
BlackRock Investment Management, LLC	668,567	$3,884,374	3.5%	Sole
BLACKROCK ADVISORS LLC	2,645,573	$15,370,779	13.8%	Sole
BlackRock Fund Advisors	7,464,072	$43,366,258	38.9%	Sole
BlackRock Institutional Trust Company, N.A.	6,302,643	$36,618,355	32.8%	Sole
BlackRock Japan Co. Ltd	25,466	$147,957	0.1%	Sole
BlackRock Fund Managers Ltd.	15,291	$88,840	0.1%	Sole
BlackRock Investment Management (UK) Ltd.	294,884	$1,713,276	1.5%	Sole
BlackRock (Netherlands) B.V.	27,425	$159,339	0.1%	Sole
BlackRock Asset Management Ireland Ltd	305,550	$1,775,245	1.6%	Sole
BlackRock (Luxembourg) S.A.	392,674	$2,281,435	2.0%	Sole
BlackRock Asset Management Schweiz AG	21,101	$122,596	0.1%	Sole
Aperio Group, LLC	84,162	$488,981	0.4%	Sole

GSK plc

$106,007,464

9.96%

18,245,691

MAVERICK CAPITAL LTD

$59,715,848

5.61%

10,278,115

Driehaus Capital Management LLC

$31,624,660

2.97%

5,443,143

PRIMECAP MANAGEMENT CO/CA/

$31,110,353

2.92%

5,354,622

683 Capital Management, LLC

$28,759,500

2.70%

4,950,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
683 Capital Partners, LP	4,950,000	$28,759,500	100.0%	Defined

FMR LLC

$28,599,590

2.69%

4,922,477

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	2,943,030	$17,099,004	59.8%	Defined
FIDELITY MANAGEMENT TRUST CO	1,979,402	$11,500,325	40.2%	Defined
STRATEGIC ADVISERS LLC	45	$261	0.0%	Defined

STATE STREET CORP

$28,116,431

2.64%

4,839,317

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	4,839,317	$28,116,431	100.0%	Defined

READYSTATE ASSET MANAGEMENT LP

$27,464,677

2.58%

4,727,139

M28 Capital Management LP

$26,657,930

2.50%

4,588,284

GEODE CAPITAL MANAGEMENT, LLC

$22,484,688

2.11%

3,869,998

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	552,752	$3,211,489	14.3%	Defined
Held directly	3,317,246	$19,273,199	85.7%	Defined

TWO SIGMA INVESTMENTS, LP

$21,541,655

2.02%

3,707,686

ALGERT GLOBAL LLC

$16,370,343

1.54%

2,817,615

Qube Research & Technologies Ltd

$16,128,560

1.52%

2,776,000

Squarepoint Ops LLC

$14,765,778

1.39%

2,541,442

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	2,541,442	$14,765,778	100.0%	Defined

MORGAN STANLEY

$14,075,913

1.32%

2,422,705

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	3,324	$19,312	0.1%	Defined
MORGAN STANLEY & CO. LLC	283,727	$1,648,453	11.7%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	2,065,542	$12,000,799	85.3%	Defined
MORGAN STANLEY SMITH BARNEY LLC	10,360	$60,191	0.4%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	59,752	$347,158	2.5%	Defined

VANGUARD PORTFOLIO MANAGEMENT LLC

$12,263,463

1.15%

2,110,751

Pfizer Inc

$10,893,750

1.02%

1,875,000

MILLENNIUM MANAGEMENT LLC

$10,523,548

0.99%

1,811,282

PRICE T ROWE ASSOCIATES INC /MD/

$10,495,572

0.99%

1,806,467

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	271,416	$1,576,926	15.0%	Defined
Held directly	1,535,051	$8,918,646	85.0%	Sole

D. E. Shaw & Co., Inc.

$10,296,644

0.97%

1,772,228

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	1,772,228	$10,296,644	100.0%	Defined

VANGUARD CAPITAL MANAGEMENT LLC

$10,175,651

0.96%

1,751,403

SCHRODER INVESTMENT MANAGEMENT GROUP

$10,147,995

0.95%

1,746,643

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Schroder Investment Management Limited	1,746,643	$10,147,995	100.0%	Sole

DIMENSIONAL FUND ADVISORS LP

$9,922,367

0.93%

1,707,809

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dimensional Fund Advisors Ltd.	17,185	$99,844	1.0%	Defined
DFA Australia Ltd.	12,102	$70,312	0.7%	Defined
Dimensional Ireland Ltd	94,837	$551,002	5.6%	Defined
Held directly	1,583,685	$9,201,209	92.7%	Sole

RENAISSANCE TECHNOLOGIES LLC

$9,903,261

0.93%

1,704,520

AQR CAPITAL MANAGEMENT LLC

$9,575,140

0.90%

1,648,045

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Petros Family Wealth, LLC	128	$743	0.0%	Other
Arax Advisory Partners	2,825	$16,413	0.2%	Other
HALBERT HARGROVE GLOBAL ADVISORS, LLC	1,577	$9,162	0.1%	Other
Stokes Family Office, LLC	21	$122	0.0%	Other
Held directly	1,643,494	$9,548,700	99.7%	Defined

GOLDMAN SACHS GROUP INC

$9,425,806

0.89%

1,622,342

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	1,527,928	$8,877,261	94.2%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	94,414	$548,545	5.8%	Defined

Point72 Asset Management, L.P.

$8,627,786

0.81%

1,484,989

FEDERATED HERMES, INC.

$8,518,818

0.80%

1,466,234

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FEDERATED EQUITY MANAGEMENT CO OF PENNSYLVANIA	70,276	$408,303	4.8%	Defined
FEDERATED MDTA LLC	1,395,958	$8,110,515	95.2%	Defined

RTW INVESTMENTS, LP

$7,843,500

0.74%

1,350,000

NORTHERN TRUST CORP

$7,282,834

0.68%

1,253,500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	1,148,933	$6,675,300	91.7%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	82,894	$481,614	6.6%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	21,673	$125,920	1.7%	Other

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$7,114,025

0.67%

1,224,445

EMERALD ADVISERS, LLC

$7,111,236

0.67%

1,223,965

MARSHALL WACE, LLP

$5,807,285

0.55%

999,533

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	999,533	$5,807,285	100.0%	Other

Pictet Asset Management Holding SA

$5,330,146

0.50%

917,409

VANGUARD FIDUCIARY TRUST CO

$5,157,403

0.48%

887,677

Aberdeen Group plc

$5,092,220

0.48%

876,458

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
abrdn Inc.	876,458	$5,092,220	100.0%	Defined

EMERALD MUTUAL FUND ADVISERS TRUST

$4,926,874

0.46%

847,999

BAKER BROS. ADVISORS LP

$4,779,526

0.45%

822,638

BNP PARIBAS ARBITRAGE, SA

$4,712,241

0.44%

811,057

CAPITAL FUND MANAGEMENT S.A.

$4,268,874

0.40%

734,746

SPHERA FUNDS MANAGEMENT LTD.

$3,708,360

0.35%

638,272

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Sphera Global Healthcare Management LP joint	638,272	$3,708,360	100.0%	Defined

JPMORGAN CHASE & CO

$3,591,577

0.34%

618,172

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JPMorgan Chase Bank, N.A.	71,344	$414,508	11.5%	Defined
J.P. Morgan Investment Management Inc.	265,614	$1,543,217	43.0%	Defined
J.P. Morgan Securities LLC	263	$1,528	0.0%	Defined
J.P. Morgan Securities plc	15,637	$90,850	2.5%	Defined
JPMorgan Asset Management (UK) Ltd	265,314	$1,541,474	42.9%	Defined

Y-Intercept (Hong Kong) Ltd

$3,544,646

0.33%

610,094

Susquehanna Portfolio Strategies, LLC

$3,533,607

0.33%

608,194

TANG CAPITAL MANAGEMENT LLC

$3,486,000

0.33%

600,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
TANG KEVIN	600,000	$3,486,000	100.0%	Other

Walleye Capital LLC

$3,401,481

0.32%

585,453

Nuveen, LLC

$3,191,327

0.30%

549,282

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	18,751	$108,943	3.4%	Defined
TIAA CREF INVESTMENT MANAGEMENT LLC joint	127,514	$740,856	23.2%	Defined
TEACHERS ADVISORS, LLC joint	403,017	$2,341,528	73.4%	Defined

BANK OF AMERICA CORP /DE/

$3,004,082

0.28%

517,054

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	442,176	$2,569,042	85.5%	Defined
MERRILL LYNCH, PIERCE, FENNER & SMITH INC.	33,979	$197,417	6.6%	Defined
BOFA SECURITIES, INC.	40,899	$237,623	7.9%	Defined

Man Group plc

$2,936,698

0.28%

505,456

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AHL Partners LLP	307	$1,783	0.1%	Defined
Numeric Investors LLC	505,149	$2,934,915	99.9%	Defined

UBS Group AG

$2,935,426

0.28%

505,237

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	1,948	$11,317	0.4%	Defined
UBS AG	503,289	$2,924,109	99.6%	Defined

CITADEL ADVISORS LLC

$2,789,694

0.26%

480,154

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	480,154	$2,789,694	100.0%	Defined

Jump Financial, LLC

$2,629,036

0.25%

452,502

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jump Trading Holdings, LLC	3,502	$20,346	0.8%	Defined
Leap GP LLC joint	449,000	$2,608,690	99.2%	Defined

XTX Topco Ltd

$2,556,010

0.24%

439,933

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	439,933	$2,556,010	100.0%	Defined

KENNEDY CAPITAL MANAGEMENT LLC

$2,493,193

0.23%

429,121

WELLINGTON MANAGEMENT GROUP LLP

$2,457,657

0.23%

423,005

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wellington Management Company LLP	138,037	$801,994	32.6%	Defined
Wellington Trust Company, NA joint	265,611	$1,543,199	62.8%	Defined
Wellington Management Australia Pty Ltd	19,357	$112,464	4.6%	Defined

Bank of New York Mellon Corp

$2,420,322

0.23%

416,579

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Investments Corporation	156,895	$911,559	37.7%	Defined
The Bank of New York Mellon	258,882	$1,504,104	62.1%	Defined
BNY Mellon, NA joint	800	$4,648	0.2%	Defined
Held directly	2	$11	0.0%	Defined

Universal- Beteiligungs- und Servicegesellschaft mbH

$2,375,674

0.22%

408,894

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Universal-Investment-Gesellschaft mbH joint	408,894	$2,375,674	100.0%	Defined

Connor, Clark & Lunn Investment Management Ltd.

$2,361,636

0.22%

406,478

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Manager 1	399,208	$2,319,398	98.2%	Sole
Held directly	7,270	$42,238	1.8%	Sole

Trexquant Investment LP

$2,208,781

0.21%

380,169

HSBC HOLDINGS PLC

$2,152,308

0.20%

370,449

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
HSBC BANK PLC	370,449	$2,152,308	100.0%	Defined

Woodline Partners LP

$2,036,585

0.19%

350,531

Ishara Investments LP

$1,905,680

0.18%

328,000

BARCLAYS PLC

$1,798,659

0.17%

309,580

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS BANK PLC	304,103	$1,766,838	98.2%	Defined
BARCLAYS CAPITAL INC.	5,477	$31,821	1.8%	Defined

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$1,739,514

0.16%

299,400

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	299,400	$1,739,514	100.0%	Other

Russell Investments Group, Ltd.

$1,608,311

0.15%

276,818

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	41,832	$243,043	15.1%	Defined
Russell Investments Capital, LLC	234,986	$1,365,268	84.9%	Defined

PLATINUM INVESTMENT MANAGEMENT LTD

$1,599,312

0.15%

275,269

Swiss National Bank

$1,514,086

0.14%

260,600

ExodusPoint Capital Management, LP

$1,458,728

0.14%

251,072

Privium Fund Management B.V.

$1,400,268

0.13%

241,010

F/m Investments LLC

$1,365,843

0.13%

235,085

MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.

$1,339,112

0.13%

230,484

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Global X Management CO LLC joint	230,484	$1,339,112	100.0%	Defined

Newtyn Management, LLC

$1,249,150

0.12%

215,000

Invesco Ltd.

$1,163,776

0.11%

200,306

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	19,118	$111,075	9.5%	Defined
Invesco Trust Co joint	55,007	$319,590	27.5%	Defined
Invesco Capital Management LLC	126,181	$733,111	63.0%	Defined

TD Asset Management Inc

$1,127,291

0.11%

194,026

ALPS ADVISORS INC

$1,125,780

0.11%

193,766

RHUMBLINE ADVISERS

$1,125,205

0.11%

193,667

Sofinnova Investments, Inc.

$1,099,559

0.10%

189,253

GSA CAPITAL PARTNERS LLP

$1,080,421

0.10%

185,959

Elmind Capital, LP

$1,033,285

0.10%

177,846

Duquesne Family Office LLC

$1,005,130

0.09%

173,000

ADAR1 Capital Management, LLC

$929,600

0.09%

160,000

WELLS FARGO & COMPANY/MN

$895,965

0.08%

154,211

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	116,247	$675,395	75.4%	Defined
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC	8,464	$49,175	5.5%	Defined
WELLS FARGO CLEARING SERVICES, LLC	29,500	$171,395	19.1%	Defined

Burkehill Global Management, LP

$871,500

0.08%

150,000

DEUTSCHE BANK AG\

$854,656

0.08%

147,101

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS INVESTMENT MANAGEMENT AMERICAS, INC	203	$1,179	0.1%	Defined
DWS Investments UK Ltd	143,898	$836,047	97.8%	Defined
Deutsche Bank S.p.A	3,000	$17,430	2.0%	Defined

BOOTHBAY FUND MANAGEMENT, LLC

$842,450

0.08%

145,000

MANUFACTURERS LIFE INSURANCE COMPANY, THE

$836,692

0.08%

144,009

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MANULIFE FINANCIAL CORP joint	144,009	$836,692	100.0%	Defined

STATE OF WISCONSIN INVESTMENT BOARD

$830,981

0.08%

143,026

CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM

$817,769

0.08%

140,752

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$775,635

0.07%

133,500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	133,500	$775,635	100.0%	Other

CITIGROUP INC

$726,546

0.07%

125,051

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	125,051	$726,546	100.0%	Defined

ALLIANCEBERNSTEIN L.P.

$724,681

0.07%

124,730

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	124,730	$724,681	100.0%	Defined

James J. Burns & Company, LLC

$666,988

0.06%

114,800

IEQ CAPITAL, LLC

$618,451

0.06%

106,446

Cetera Investment Advisers

$609,341

0.06%

104,878

LOS ANGELES CAPITAL MANAGEMENT LLC

$608,336

0.06%

104,705

VANGUARD ASSET MANAGEMENT, Ltd

$604,210

0.06%

103,995

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$593,782

0.06%

102,200

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	102,200	$593,782	100.0%	Other

Mariner, LLC

$593,752

0.06%

102,195

Key facts CIK 1631574 CUSIP 94352A104 13F (30d) 7 filings 7 filers Visit website Investor relations