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PYXS

Pyxis Oncology, Inc.
$2.46 -0.17 (-6.46%) At close · Jul 6
Market Cap
$187.22M
Shares
63,355,482

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Holders: 78
Total Value: $40,448,933
Total Shares: 27,704,775

Institutional Ownership Trend

18 quarters

Holder Concentration

Across 78 13F filers · Δ vs Dec 31, 2025
Top Holder
25.4%
Jun 2023 → Mar 2026 · range 14.7% – 40.5%
+2.3 pts
Top 5
69.3%
Jun 2023 → Mar 2026 · range 53.3% – 74.2%
+6.0 pts
Top 10
82.6%
Jun 2023 → Mar 2026 · range 72.2% – 87.8%
+6.3 pts
HHI
1,310
Jun 2023 → Mar 2026 · range 711 – 1,989
Broadly held+219

Quarterly Activity

vs Dec 31, 2025
New
14
Increased
10
Decreased
37
Sold Out
15
Unchanged
17
Holder count: -1
Institutional value: -0.4%
Shares held: -21.5%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Large RENAISSANCE TECHNOLOGIES LLC +160,300 888,680
Mega GEODE CAPITAL MANAGEMENT, LLC +20,910 598,121
Mid BRIDGEWAY CAPITAL MANAGEMENT, LLC +8,560 81,260
Mega STATE STREET CORP +7,200 248,837
Mega BlackRock, Inc. +4,762 788,839

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Mid Laurion Capital Management LP −4,595,625 4,997,333
Mega BANK OF AMERICA CORP /DE/ −571,044 16,807
Mega JANE STREET GROUP, LLC −456,051 329,959
Small Atle Fund Management AB −420,209 197,036
Mega MILLENNIUM MANAGEMENT LLC −345,482 397,625

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
Mega VANGUARD CAPITAL MANAGEMENT LLC 2,033,510 $2,968,924
Large JACOBS LEVY EQUITY MANAGEMENT, INC 460,997 $673,055
Mega VANGUARD FIDUCIARY TRUST CO 300,897 $439,309
Large ACADIAN ASSET MANAGEMENT LLC 144,256 $210,613
Large PANAGORA ASSET MANAGEMENT INC 69,424 $101,359

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mega VANGUARD GROUP INC 2,335,768 $2,686,132
Large ExodusPoint Capital Management, LP 317,769 $365,434
Mid Quadrature Capital Ltd 100,536 $115,616
Large OMERS ADMINISTRATION Corp 67,000 $77,050
Small Velan Capital Investment Management LP 40,000 $46,000
Filter: New 14 Increased 10 Reduced 37 Sold out 15 Unchanged 17
Showing 81 of 81
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Open
Small Pfizer Inc $10,267,843 25.38% 7,032,770
Mid Laurion Capital Management LP $7,296,106 18.04% 4,997,333
Small GordonMD Global Investments LP $6,017,930 14.88% 4,121,870
Mega VANGUARD CAPITAL MANAGEMENT LLC $2,968,924 7.34% 2,033,510
Small Palo Alto Investors LP $1,475,344 3.65% 1,010,510
Mid 683 Capital Management, LLC $1,308,543 3.24% 896,263
Large RENAISSANCE TECHNOLOGIES LLC $1,297,472 3.21% 888,680
Mega BlackRock, Inc. $1,151,703 2.85% 788,839
Mega GEODE CAPITAL MANAGEMENT, LLC $873,256 2.16% 598,121
Mid Longaeva Partners L.P. $734,692 1.82% 503,214
Large JACOBS LEVY EQUITY MANAGEMENT, INC $673,055 1.66% 460,997
Mega MILLENNIUM MANAGEMENT LLC $580,532 1.44% 397,625
Large MARSHALL WACE, LLP $517,448 1.28% 354,417
Small Decheng Capital LLC $477,142 1.18% 326,810
Mega JANE STREET GROUP, LLC $444,509 1.10% 304,459
Mega VANGUARD FIDUCIARY TRUST CO Bank $439,309 1.09% 300,897
Mega UBS Group AG $371,021 0.92% 254,124
Mega STATE STREET CORP $363,302 0.90% 248,837
Mid XTX Topco Ltd $292,140 0.72% 200,096
Small Atle Fund Management AB $287,672 0.71% 197,036
Large ACADIAN ASSET MANAGEMENT LLC $210,613 0.52% 144,256
Mega Bank of New York Mellon Corp Bank $195,632 0.48% 133,996
Mid NewEdge Wealth, LLC $169,368 0.42% 116,006
Mega NORTHERN TRUST CORP Bank $148,844 0.37% 101,948
Mid BRIDGEWAY CAPITAL MANAGEMENT, LLC $118,639 0.29% 81,260
Mega TWO SIGMA INVESTMENTS, LP $107,018 0.26% 73,300
Mega MORGAN STANLEY $101,744 0.25% 69,688
Large PANAGORA ASSET MANAGEMENT INC $101,359 0.25% 69,424
Mega CITADEL ADVISORS LLC $97,966 0.24% 67,100
Small Cable Car Capital, LP $89,944 0.22% 61,606
Mega CITADEL ADVISORS LLC $89,423 0.22% 61,249
Large STIFEL FINANCIAL CORP $73,784 0.18% 50,537
Large TORONTO DOMINION BANK Bank $73,000 0.18% 50,000
Mega BARCLAYS PLC $72,743 0.18% 49,825
Micro UNIVERSITY OF CHICAGO Endowment $71,147 0.18% 48,731
Mega GOLDMAN SACHS GROUP INC $68,503 0.17% 46,920
Small J. Derek Lewis & Associates Inc. $62,780 0.16% 43,000
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $61,758 0.15% 42,300
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $60,153 0.15% 41,201
Large COMMONWEALTH EQUITY SERVICES, LLC $50,742 0.13% 34,755
Mega LPL Financial LLC $48,988 0.12% 33,554
Large Point72 Asset Management, L.P. $46,728 0.12% 32,006
Large Cetera Investment Advisers $39,799 0.10% 27,260
Mega DIMENSIONAL FUND ADVISORS LP $37,830 0.09% 25,912
Mega JANE STREET GROUP, LLC $37,230 0.09% 25,500
Mid Graham Capital Management, L.P. $33,212 0.08% 22,748
Small Maia Wealth LLC $31,064 0.08% 21,277
Mega Vanguard Global Advisers, LLC $31,013 0.08% 21,242
Small Catalyst Funds Management Pty Ltd $29,784 0.07% 20,400
Large Squarepoint Ops LLC $25,604 0.06% 17,537
Mega BANK OF AMERICA CORP /DE/ Bank $24,538 0.06% 16,807
Large OSAIC HOLDINGS, INC. $20,032 0.05% 13,721
Small TWO SIGMA SECURITIES, LLC Broker-Dealer $19,672 0.05% 13,474
Mega FMR LLC $17,391 0.04% 11,912
Small PACES FERRY WEALTH ADVISORS, LLC $16,702 0.04% 11,440
Large Qube Research & Technologies Ltd $16,477 0.04% 11,286
Mid China Universal Asset Management Co., Ltd. $16,131 0.04% 11,049
Mid Tower Research Capital LLC (TRC) $15,084 0.04% 10,332
Large NewEdge Advisors, LLC $14,965 0.04% 10,250
Mega PNC FINANCIAL SERVICES GROUP, INC. $9,490 0.02% 6,500
Small Winthrop Capital Management, LLC $8,760 0.02% 6,000
Mega ROYAL BANK OF CANADA Bank $8,524 0.02% 5,839
Mega JPMORGAN CHASE & CO $7,552 0.02% 5,173
Small HAGER INVESTMENT MANAGEMENT SERVICES, LLC $7,300 0.02% 5,000
Large Mirae Asset Global Investments Co., Ltd. $4,742 0.01% 3,248
Large FEDERATED HERMES, INC. $4,644 0.01% 3,181
Mega CITIGROUP INC $2,540 0.01% 1,740
Mega BNP PARIBAS ARBITRAGE, SA $2,414 0.01% 1,654
Mid GF FUND MANAGEMENT CO. LTD. $1,921 0.00% 1,316
Large NISA INVESTMENT ADVISORS, LLC $1,403 0.00% 961
Small Physician Wealth Advisors, Inc. $1,376 0.00% 943
Large Balyasny Asset Management L.P. $1,084 0.00% 743
Large JONES FINANCIAL COMPANIES LLLP $730 0.00% 500
Mega WELLS FARGO & COMPANY/MN $416 0.00% 285
Mid SIMPLEX TRADING, LLC $369 0.00% 253
Micro Cornerstone Financial Management LLC $251 0.00% 172
Large CWM, LLC $49 0.00% 34
Small Ascentis Independent Advisors $14 0.00% 10
Small Caitong International Asset Management Co., Ltd $5 0.00% 4
Mid Arax Advisory Partners $1 0.00% 1
Mid SBI Securities Co., Ltd. Broker-Dealer $1 0.00% 1
Key facts CIK 1782223 CUSIP 747324101 13F (30d) 1 filings 1 filers Visit website Investor relations

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