QTTB · Q32 Bio Inc. · Holdings

$10.53 -0.61 (-5.47%) At close · Sep 10

Market Cap

$331.63M

29.77M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP →

Quarter:

Holders: 71

Total Value: $285,890,364

Total Shares: 22,440,377

Institutional Ownership Trend

26 quarters

Holder Concentration

Across 71 13F filers · Δ vs Mar 31, 2026

Top Holder

18.4%

−5.5 pts

Top 5

65.4%

−9.1 pts

Top 10

84.4%

−4.1 pts

HHI

991

Broadly held−450

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

Sold Out

Unchanged

Holder count: +17

Institutional value: +372.3%

Shares held: +138.0%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Mid ORBIMED ADVISORS LLC	+1,875,000	4,127,987
Small Atlas Venture Life Science Advisors, LLC	+625,000	2,717,106
Mega AMERICAN CENTURY COMPANIES INC	+253,982	272,752
Mega VANGUARD CAPITAL MANAGEMENT LLC	+212,402	518,803
Mega CITADEL ADVISORS LLC	+105,182	120,663

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Large Carlyle Group Inc.	−1,042,378	60,363
Mid Opaleye Management Inc.	−325,228	931,000
Small ACORN CAPITAL ADVISORS, LLC	−98,881	216,171
Large RENAISSANCE TECHNOLOGIES LLC	−27,315	179,600
Large Cambridge Investment Research Advisors, Inc.	−16,944	18,081

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Mid Boxer Capital Management, LLC	3,149,310	$40,122,209
Mid BVF INC/IL	2,350,000	$29,939,000
Large RA CAPITAL MANAGEMENT, L.P.	2,332,457	$29,715,502
Large Point72 Asset Management, L.P.	1,173,396	$14,949,065
Mid Logos Global Management LP	800,000	$10,192,000

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Mid ARCH Venture Management, LLC	320,482	$2,057,494
Large MACKENZIE FINANCIAL CORP	246,304	$1,581,271
Small Pfizer Inc	101,618	$652,387
Mid ADAR1 Capital Management, LLC	35,000	$224,700
Large Cetera Investment Advisers	20,695	$132,861

Filter: New 27 Increased 17 Reduced 14 Sold out 10 Unchanged 13

Showing 73 of 73

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

ORBIMED ADVISORS LLC

$52,590,554

18.40%

4,127,987

Boxer Capital Management, LLC

$40,122,209

14.03%

3,149,310

Atlas Venture Life Science Advisors, LLC

$34,615,930

12.11%

2,717,106

BVF INC/IL

$29,939,000

10.47%

2,350,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BVF PARTNERS L P/IL	2,350,000	$29,939,000	100.0%	Defined

RA CAPITAL MANAGEMENT, L.P.

$29,715,502

10.39%

2,332,457

Point72 Asset Management, L.P.

$14,949,065

5.23%

1,173,396

Opaleye Management Inc.

$11,860,940

4.15%

931,000

Logos Global Management LP

$10,192,000

3.57%

800,000

SummitTX Capital, L.P.

$9,348,280

3.27%

733,774

VANGUARD CAPITAL MANAGEMENT LLC

$6,609,550

2.31%

518,803

Ikarian Capital, LLC

$5,478,200

1.92%

430,000

Woodline Partners LP

$3,646,340

1.28%

286,212

AMERICAN CENTURY COMPANIES INC

$3,474,860

1.22%

272,752

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AMERICAN CENTURY INVESTMENT MANAGEMENT INC	272,752	$3,474,860	100.0%	Defined

Sanofi

$3,109,617

1.09%

244,083

ACADIAN ASSET MANAGEMENT LLC

$2,780,301

0.97%

218,234

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Acadian Inc	218,234	$2,780,301	100.0%	Defined

ACORN CAPITAL ADVISORS, LLC

$2,754,018

0.96%

216,171

Ikarian Capital, LLC

$2,548,000

0.89%

200,000

RENAISSANCE TECHNOLOGIES LLC

$2,288,104

0.80%

179,600

JANE STREET GROUP, LLC

$2,073,396

0.73%

162,747

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	132,352	$1,686,164	81.3%	Defined
Jane Street Global Trading, LLC	30,395	$387,232	18.7%	Defined

MONIMUS CAPITAL MANAGEMENT, LP

$1,682,138

0.59%

132,036

BOOTHBAY FUND MANAGEMENT, LLC

$1,661,639

0.58%

130,427

GEODE CAPITAL MANAGEMENT, LLC

$1,563,070

0.55%

122,690

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	22,767	$290,051	18.6%	Defined
Held directly	99,923	$1,273,019	81.4%	Defined

CITADEL ADVISORS LLC

$1,537,246

0.54%

120,663

BlackRock, Inc.

$1,509,777

0.53%

118,507

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BlackRock Investment Management, LLC	1,966	$25,046	1.7%	Sole
BlackRock Fund Advisors	29,465	$375,384	24.9%	Sole
BlackRock Institutional Trust Company, N.A.	85,882	$1,094,136	72.5%	Sole
Aperio Group, LLC	1,194	$15,211	1.0%	Sole

MARSHALL WACE, LLP

$854,153

0.30%

67,045

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	67,045	$854,153	100.0%	Other

VANGUARD FIDUCIARY TRUST CO

$843,604

0.30%

66,217

BOOTHBAY FUND MANAGEMENT, LLC

$780,962

0.27%

61,300

Carlyle Group Inc.

$769,024

0.27%

60,363

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Abingworth LLP	60,363	$769,024	100.0%	Defined

STATE STREET CORP

$665,206

0.23%

52,214

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS TRUST COMPANY	52,214	$665,206	100.0%	Defined

TWO SIGMA INVESTMENTS, LP

$631,674

0.22%

49,582

Quadrature Capital Ltd

$463,685

0.16%

36,396

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Quadrature US Inc.	36,396	$463,685	100.0%	Other

BRIDGEWAY CAPITAL MANAGEMENT, LLC

$440,969

0.15%

34,613

DAFNA Capital Management LLC

$419,095

0.15%

32,896

Knott David M Jr

$387,448

0.14%

30,412

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dorset Partners LLC	30,412	$387,448	100.0%	Defined

Affinity Asset Advisors, LLC

$353,878

0.12%

27,777

Squarepoint Ops LLC

$303,084

0.11%

23,790

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	23,790	$303,084	100.0%	Defined

NORTHERN TRUST CORP

$301,058

0.11%

23,631

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	23,631	$301,058	100.0%	Defined

DIMENSIONAL FUND ADVISORS LP

$300,510

0.11%

23,588

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dimensional Ireland Ltd	3,505	$44,653	14.9%	Defined
Held directly	20,083	$255,857	85.1%	Sole

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$297,377

0.10%

23,342

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	23,342	$297,377	100.0%	Other

MANGROVE PARTNERS IM, LLC

$282,191

0.10%

22,150

LPL Financial LLC

$231,485

0.08%

18,170

Cambridge Investment Research Advisors, Inc.

$230,351

0.08%

18,081

HRT FINANCIAL LP

$203,190

0.07%

15,949

UBS Group AG

$191,201

0.07%

15,008

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS AG	14,419	$183,698	96.1%	Defined
UBS Switzerland AG	489	$6,229	3.3%	Defined
UBS Securities LLC	100	$1,274	0.7%	Defined

Balyasny Asset Management L.P.

$157,237

0.05%

12,342

ExodusPoint Capital Management, LP

$144,420

0.05%

11,336

MILLENNIUM MANAGEMENT LLC

$139,222

0.05%

10,928

XTX Topco Ltd

$138,534

0.05%

10,874

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	10,874	$138,534	100.0%	Defined

MORGAN STANLEY

$82,246

0.03%

6,456

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	1	$12	0.0%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	516	$6,573	8.0%	Defined
MORGAN STANLEY SMITH BARNEY LLC	1,593	$20,294	24.7%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	4,346	$55,367	67.3%	Defined

Vanguard Global Advisers, LLC

$61,457

0.02%

4,824

FMR LLC

$43,163

0.02%

3,388

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	3,388	$43,163	100.0%	Defined

CITIGROUP INC

$36,793

0.01%

2,888

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	2,888	$36,793	100.0%	Defined

Private Wealth Asset Management, LLC

$21,658

0.01%

1,700

Arax Advisory Partners

$14,154

0.00%

1,111

FEDERATED HERMES, INC.

$13,377

0.00%

1,050

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FEDERATED MDTA LLC	1,050	$13,377	100.0%	Defined

Rockefeller Capital Management L.P.

$7,350

0.00%

577

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ROCKEFELLER FINANCIAL LLC	577	$7,350	100.0%	Defined

JONES FINANCIAL COMPANIES LLLP

$6,370

0.00%

500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Edward D. Jones & Co., L.P.	500	$6,370	100.0%	Sole

Russell Investments Group, Ltd.

$5,783

0.00%

454

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	454	$5,783	100.0%	Defined

BNP PARIBAS ARBITRAGE, SA

$3,860

0.00%

303

EverSource Wealth Advisors, LLC

$3,057

0.00%

240

NISA INVESTMENT ADVISORS, LLC

$2,114

0.00%

166

Truvestments Capital LLC

$2,063

0.00%

162

OSAIC HOLDINGS, INC.

$1,579

0.00%

124

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
OSAIC WEALTH, INC.	124	$1,579	100.0%	Defined

Allworth Financial LP

$1,375

0.00%

108

SBI Securities Co., Ltd.

$1,197

0.00%

Federation des caisses Desjardins du Quebec

$891

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Desjardins Securities inc.	38	$484	54.3%	Defined
Held directly	32	$407	45.7%	Defined

Clearstead Advisors, LLC

$853

0.00%

Caitong International Asset Management Co., Ltd

$573

0.00%

ROYAL BANK OF CANADA

$547

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC Capital Markets, LLC	28	$356	65.1%	Defined
Held directly	15	$191	34.9%	Sole

GROUP ONE TRADING LLC

$433

0.00%

HARBOUR INVESTMENTS, INC.

$140

0.00%

AdvisorNet Financial, Inc

$25

0.00%

DANSKE BANK A/S

$12

0.00%

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Latour Trading LLC (Latour)	1,871	$12,011	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO CLEARING SERVICES, LLC	84	$539	100.0%	Defined

Key facts CIK 1661998 CUSIP 746964105 13F (30d) 51 filings 51 filers Visit website Investor relations