Equibles

QTTB

Q32 Bio Inc.

Company with tickers: QTTB

CIK
1661998
CUSIP
746964105
Shares Outstanding
16,956,415
13F Activity (30d)
52 filings 50 filers
Holders: 53
Total Value: $60,533,500
Total Shares: 9,428,899

Institutional Ownership Trend

9 quarters

Holder Concentration

Across 53 13F filers · Δ vs Dec 31, 2025
Top Holder
23.9%
Mar 2024 → Mar 2026 · range 20.3% – 30.1%
−4.1 pts
Top 5
74.5%
Mar 2024 → Mar 2026 · range 62.5% – 82.1%
−3.4 pts
Top 10
88.5%
Mar 2024 → Mar 2026 · range 80.5% – 95.1%
−3.8 pts
HHI
1,440
Mar 2024 → Mar 2026 · range 1,045 – 1,994
Broadly held −313

Quarterly Activity

vs Dec 31, 2025
New
11
Increased
14
Decreased
9
Sold Out
10
Unchanged
19
Holder count: +1
Institutional value: +126.7%
Shares held: +17.2%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Small Opaleye Management Inc. +1,042,865 1,256,228
Large ACADIAN ASSET MANAGEMENT LLC +124,213 172,586
Large RENAISSANCE TECHNOLOGIES LLC +107,315 206,915
Mega JANE STREET GROUP, LLC +40,225 65,599
Mega BlackRock, Inc. +26,215 86,147

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Small ACORN CAPITAL ADVISORS, LLC −178,373 315,052
Small Pfizer Inc −176,159 101,618
Mega CITADEL ADVISORS LLC −30,247 15,481
Mega UBS Group AG −13,336 270
Mega TWO SIGMA INVESTMENTS, LP −4,479 42,346

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
Mega VANGUARD CAPITAL MANAGEMENT LLC 306,401 $1,967,094
Large MACKENZIE FINANCIAL CORP 246,304 $1,581,271
Small MONIMUS CAPITAL MANAGEMENT, LP 134,310 $862,270
Large MARSHALL WACE, LLP 52,440 $336,664
Mega VANGUARD FIDUCIARY TRUST CO 49,995 $320,967

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mega VANGUARD GROUP INC 321,051 $1,065,888
Mega MILLENNIUM MANAGEMENT LLC 51,268 $170,209
Small Monaco Asset Management SAM 50,919 $169,051
Large HRT FINANCIAL LP 24,698 $81,997
Mid XTX Topco Ltd 20,353 $67,571
Filter: New 11 Increased 14 Reduced 9 Sold out 10 Unchanged 19
Showing 53 of 53
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Open
Mid ORBIMED ADVISORS LLC $14,464,176 23.89% 2,252,987
Small Atlas Venture Life Science Advisors, LLC $13,431,320 22.19% 2,092,106
Small Opaleye Management Inc. $8,064,983 13.32% 1,256,228
Large Carlyle Group Inc. $7,079,597 11.70% 1,102,741
Small ARCH Venture Management, LLC $2,057,494 3.40% 320,482
Small ACORN CAPITAL ADVISORS, LLC $2,022,633 3.34% 315,052
Mega VANGUARD CAPITAL MANAGEMENT LLC $1,967,094 3.25% 306,401
Large MACKENZIE FINANCIAL CORP $1,581,271 2.61% 246,304
Small Sanofi $1,567,012 2.59% 244,083
Large RENAISSANCE TECHNOLOGIES LLC $1,328,394 2.19% 206,915
Large ACADIAN ASSET MANAGEMENT LLC $1,108,002 1.83% 172,586
Small MONIMUS CAPITAL MANAGEMENT, LP $862,270 1.42% 134,310
Mega GEODE CAPITAL MANAGEMENT, LLC $758,534 1.25% 118,152
Small Pfizer Inc $652,387 1.08% 101,618
Mega BlackRock, Inc. $553,063 0.91% 86,147
Mega JANE STREET GROUP, LLC $421,145 0.70% 65,599
Large MARSHALL WACE, LLP $336,664 0.56% 52,440
Mega VANGUARD FIDUCIARY TRUST CO Bank $320,967 0.53% 49,995
Mega TWO SIGMA INVESTMENTS, LP $271,861 0.45% 42,346
Mega STATE STREET CORP $266,519 0.44% 41,514
Large Cambridge Investment Research Advisors, Inc. $224,860 0.37% 35,025
Mid ADAR1 Capital Management, LLC $224,700 0.37% 35,000
Mid Affinity Asset Advisors, LLC $178,328 0.29% 27,777
Mega NORTHERN TRUST CORP Bank $160,711 0.27% 25,033
Large Cetera Investment Advisers $132,861 0.22% 20,695
Mega AMERICAN CENTURY COMPANIES INC $120,503 0.20% 18,770
Mega CITADEL ADVISORS LLC $99,388 0.16% 15,481
Mid BRIDGEWAY CAPITAL MANAGEMENT, LLC $80,975 0.13% 12,613
Mega MORGAN STANLEY $61,373 0.10% 9,560
Mid EverSource Wealth Advisors, LLC $29,787 0.05% 4,640
Mega FMR LLC $21,828 0.04% 3,400
Mega ROYAL BANK OF CANADA Bank $17,615 0.03% 2,744
Large FEDERATED HERMES, INC. $14,592 0.02% 2,273
Mega Vanguard Global Advisers, LLC $12,294 0.02% 1,915
Mid Tower Research Capital LLC (TRC) $12,011 0.02% 1,871
Mid Arax Advisory Partners $7,370 0.01% 1,148
Large Rockefeller Capital Management L.P. $3,704 0.01% 577
Large JONES FINANCIAL COMPANIES LLLP $3,210 0.01% 500
Large Russell Investments Group, Ltd. $2,914 0.00% 454
Mega BNP PARIBAS ARBITRAGE, SA $1,945 0.00% 303
Mega UBS Group AG $1,733 0.00% 270
Large NISA INVESTMENT ADVISORS, LLC $1,065 0.00% 166
Large OSAIC HOLDINGS, INC. $796 0.00% 124
Large NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO $712 0.00% 111
Mid SBI Securities Co., Ltd. Broker-Dealer $667 0.00% 104
Mid Allworth Financial LP $629 0.00% 98
Mega WELLS FARGO & COMPANY/MN $539 0.00% 84
Large Federation des caisses Desjardins du Quebec $448 0.00% 70
Large CWM, LLC $250 0.00% 39
Mid GROUP ONE TRADING LLC $218 0.00% 34
Mid HARBOUR INVESTMENTS, INC. $70 0.00% 11
Small AdvisorNet Financial, Inc $12 0.00% 2
Large DANSKE BANK A/S Bank $6 0.00% 1

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