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PYXS · Pyxis Oncology, Inc.

Track PYXS — free
$2.06 +0.04 (+1.95%) At close · Oct 7
Market Cap
$238.55M
Shares
83.41M
Volume · Oct 7 958K Avg daily vol (3M) 1.28M

Price & Indicators

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20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$2.02 Open$2.22 Day$2.00–2.22 52W close$1.06–5.34 Avg vol 30d1.2M Short int4.7M · 5.6% float · 3.7d Short vol67% Last earningsMay 20, 2026 DataOct 2021–Oct 2026 Filing10-Q · Aug 13

Up next

Next earnings call
Jun 15, 2028 Est · unconfirmed · in 88 wks
filed Aug 13, 2026

Metrics snapshot

Useful current figures from the complete screener profile.

Revenue (TTM)
—
Trailing 12 months
Net income (TTM)
−$88.73M
Trailing 12 months
Revenue growth YoY
-14.2%
Year over year
Operating margin
-609.2%
Trailing 12 months
P / E (TTM)
—
Trailing earnings
FCF yield
—
TTM · current market cap
Return on invested capital
—
Trailing 12 months
Net cash
$33.00M
Latest balance sheet
Dividend yield
—
Trailing 12 months
Shares change YoY
+3.3%
Year over year · more shares
Price change (1Y)
-18.2%
Trailing year
Short interest
5.6%
Latest settlement · 3.7 days to cover
View all 115 metrics

Equibles Rating

blended score · not investment advice
Overall
Sell
SellHoldBuy
Technical Sell Momentum Strong Sentiment Neutral Fundamentals Poor Quant / Vol Very High
Market backdrop VIX 15.1 · calm Equity put/call 0.63
Technical
price trend
Sell
50 / 200-day cross No cross
Price vs 200-day avg −5%
below
Price vs 50-day avg −35%
below
RSI (14) 29
oversold
MACD trend Negative
52-week position 22%
mid-range
Volume (OBV) Confirms
volume backs price
Momentum
relative strength
Strong
1-month return −48%
trailing
6-month return +18%
trailing
YTD return +76%
this year
Relative strength +7%
vs S&P · 6-mo
Sentiment
smart money
Neutral
Trend (MA cross) No cross
50d $3 › 200d $2 — 50d above 200d
Institutional flow Accumulating
+1% holders QoQ · +11 funds added
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
5.61% of float · ▲ +17.9% MoM · 3.7 days cover
Volume signal Normal
Volume near normal
Institution breadth Steady
79 holders — mid 3-yr range
Squeeze score 58
elevated · 0–100
Fundamentals
Poor
Revenue growth −14%
Y/Y
EPS growth +3%
Y/Y
Free cash flow $-63.5M
Quant / Vol
risk profile
Very High
Volatility 131%
annualized · 1-yr
Max drawdown −80%
past year
ATR 13.6%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Technicals

trend & momentum for long-term holders Sell
2 · 5 · 0
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
−5% Neutral
Price vs 50-day avg
−35% Bearish
RSI (14)
29 Neutral
MACD trend
Negative Bearish
52-week position
22% Neutral
Volume (OBV)
Confirms Neutral
Market signals — smart money & positioning
Mixed
Trend (MA cross) No cross
50d $3 › 200d $2 — 50d above 200d
Institutional flow Accumulating
+1% holders QoQ · +11 funds added
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
5.61% of float · ▲ +17.9% MoM · 3.7 days cover
Volume signal Normal
Volume near normal
Institution breadth Steady
79 holders — mid 3-yr range
Price context
position in its 52-week range
Range low $1 Now $2 · 22% Range high $5
vs 200-day avg -5% vs 50-day avg -35%

Illustrative technical + ownership context — a signal mix, not investment advice.

Key metrics

Earlier KPI extraction records exist, but do not meet the current evidence-completeness requirements. No current verified series is available. Earlier figures remain withheld until revalidated; this is not evidence that the company reports no KPIs.

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
PYXS
Pyxis Oncology, Inc.
this stock
$238.55M +75.7% -14.2% — 5.6%
VRTX
Vertex Pharmaceuticals Inc / Ma
$133.37B +10.8% +46.2% 30.7 1.9%
REGN
Regeneron Pharmaceuticals, Inc.
$81.13B -4.3% +20.8% 19.5 2.5%
MRNA
Moderna, Inc.
$78.44B +535.7% +4.3% — 8.2%
CSLLY
Csl Ltd
$61.25B — — — 0.0%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Accumulating
Holders
79
% held
41.6%
Net QoQ
+7.0M sh
Top holder
GordonMD Global Investmen…
Held Float
View
Held by Funds
Fund positions
20
View
Short & Settlement
Short Interest Rising
Shares short
4.7M
Days to cover
3.7d
Change
+710.4K sh
View
Short Volume
Short vol %
67%
As of
Oct 7, 2026
Short Total
View
Fails to Deliver
FTD shares
15.1K
Value
$49.4K
As of
Sep 11, 2026
View
Off-Exchange
Off-exchange %
45.6%
Week of
Aug 31, 2026
Off-exch Lit
View
Financials
Financials
Revenue (FY)
$13.9M
Net income (FY)
$-79.6M
EPS diluted
$-1.28
View
Buybacks
Authorized
shares 2.7M
View
Filings
SEC Filings
Latest
8-K
Filed
Oct 1, 2026
This year
15
View
Proposed Sales
Value
$107.0K
Shares
35.0K
Filed
Jun 30, 2026
View
Exempt Offerings
Offering
$172.5M
Filed
Mar 22, 2021
View
Earnings & Events
Webcasts
Last webcast
Jun 4, 2026
View

Performance

5D 20D 120D MTD YTD
PYXS -30.3% -48.1% +18.1% -13.3% +75.7%
SPY +2.0% +1.7% +11.3% +2.2% +14.3%
vs SPY -32.3% -49.8% +6.8% -15.5% +61.4%

Capital returns

Buyback program · as of Sep 30, 2022
Authorized
shares 2.74M
Spent (derived)
—
Remaining
—

Dividends per share over the trailing 365 days by ex-date · buyback figures as last reported in SEC filings ("spent" derived as authorized − remaining; when several programs run concurrently, authorized is their combined total per the newest filing) · components shown separately — trailing-year buyback spend isn't tracked, so no combined shareholder yield is derived.

Key facts CIK 1782223 CUSIP 747324101 13F (30d) 1 filings 1 filers Visit website Investor relations