PYXS · Pyxis Oncology, Inc. · Shareholders & Ownership

$1.68 -0.03 (-1.75%) At close · Oct 23

Market Cap

$140.13M

83.41M

Volume · Oct 23 626.79K Avg daily vol (3M) 1.23M

Every disclosed holder of PYXS in one list: 13F institutions, Schedule 13D and 13G filers, insiders (Forms 3, 4 and 5) and registered funds, each from its own latest filing. Holders nest by CIK and SEC reporting links, never by name, and each is summed once.

How the holder list picks a filing →

Who Owns PYXS

13F quarter Sep 30, 2026, combined view: filers that have not filed yet carry their Jun 30, 2026 positions

Holder group	Holders	Shares	% Out	Summed
Institutional (13F)	81	34,222,182	41.03%	Yes
Insiders (Forms 3, 4, 5)	4	2,947,818	3.53%	Yes
13D/G-only blocks	6	27,918,464	33.47%	Yes
Remaining	—	18,319,586	21.96%	Rest
Registered funds (N-PORT, not summed)	18	3,161,477	3.79%	No

Shares outstanding: 83,408,050, the issuer's latest cover-page count restated onto today's split basis.

13D/G-only counts each filer's latest 13D or 13G that no 13F report of the listing contains, that names no 13F filer and that no counted insider files. Funds are never summed: their shares sit inside their advisers' 13F reports.

Holders of PYXS

One row per holder Every filing By ultimate parent

All 13F Funds Insiders 13D/G Non-US

#	Holder	Shares	% Out	Change	As of	Notes
1	GordonMD Global Investments LP 13G CIK 2039349 · Unknown · Oct 1, 2026 Rule 13d-1(c), passive investor, not summed	20,441,948	24.51%	+10,417,039	Oct 1, 2026	Rule 13d-1(c), passive investor, not summed
1.1	GordonMD Global Investments LP 13F CIK 2039349 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	10,024,909	12.02%	+5,903,039	Jun 30, 2026	carried, not yet filed for the newest quarter
1.2	GordonMD Global Investments LP Insider CIK 2039349 · Jun 30, 2026 10% Owner, issuer-wide, not summed	10,024,909	12.02%	—	Jun 30, 2026	10% Owner, issuer-wide, not summed
2	BIOTECHNOLOGY VALUE FUND L P 13G CIK 918923 · Unknown · Jul 2, 2026 Rule 13d-1(c), passive investor	8,336,902	10.00%	+8,336,902	Jul 2, 2026	Rule 13d-1(c), passive investor
3	Lara Sullivan 13D CIK 1769457 · Unknown · Mar 31, 2025	7,543,007	9.04%	+918,308	Mar 31, 2025
4	Pfizer Inc 13F CIK 78003 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	7,032,770	8.43%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
5	Coastlands Capital LP 13G CIK 2068530 · Investment adviser · Oct 1, 2026 Rule 13d-1(b), qualified institution	6,448,907	7.73%	—	Oct 1, 2026	Rule 13d-1(b), qualified institution
6	Laurion Capital Management LP 13F CIK 1390202 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	4,900,888	5.88%	-96,445	Jun 30, 2026	carried, not yet filed for the newest quarter
7	Bayer World Investments B.V. 13G CIK 1820027 · Unknown · Sep 30, 2024 Rule 13d-1(d), exempt investor	2,742,338	3.29%	—	Sep 30, 2024	Rule 13d-1(d), exempt investor
8	Millennium Management LLC 13G CIK 1319244 · Unknown · Mar 31, 2025 Rule 13d-1(c), passive investor	2,488,079	2.98%	-672,060	Mar 31, 2025	Rule 13d-1(c), passive investor
9	Connealy Pamela Ann Insider CIK 1796310 · Nov 26, 2024 CFO & COO, issuer-wide	2,314,886	2.78%	+1,204,593	Nov 26, 2024	CFO & COO, issuer-wide
10	VANGUARD CAPITAL MANAGEMENT LLC 13F CIK 2100119 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	2,075,997	2.49%	+42,487	Jun 30, 2026	carried, not yet filed for the newest quarter
11	VANGUARD TOTAL STOCK MARKET INDEX FUND Fund S000002848 · Registered fund · Jun 30, 2026 VANGUARD INDEX FUNDS, not summed	1,422,296	1.71%	0	Jun 30, 2026	VANGUARD INDEX FUNDS, not summed
12	Atle Fund Management AB 13F CIK 1381843 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	966,459	1.16%	+769,423	Jun 30, 2026	carried, not yet filed for the newest quarter
13	BlackRock, Inc. 13F CIK 2012383 · Holding company · Jun 30, 2026 carried, not yet filed for the newest quarter	867,934	1.04%	+79,095	Jun 30, 2026	carried, not yet filed for the newest quarter
13.1	iShares Biotechnology ETF Fund S000004350 · Registered fund · Jun 30, 2026 iShares Trust, not summed	374,680	0.45%	+29,550	Jun 30, 2026	iShares Trust, not summed
13.2	iShares Micro-Cap ETF Fund S000004439 · Registered fund · Jun 30, 2026 iShares Trust, not summed	166,564	0.20%	+42,736	Jun 30, 2026	iShares Trust, not summed
14	Palo Alto Investors LP 13F CIK 1306923 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	864,277	1.04%	-146,233	Jun 30, 2026	carried, not yet filed for the newest quarter
15	MARSHALL WACE, LLP 13F CIK 1318757 · Exempt reporting adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	830,544	1.00%	+476,127	Jun 30, 2026	carried, not yet filed for the newest quarter
16	RENAISSANCE TECHNOLOGIES LLC 13F CIK 1037389 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	772,232	0.93%	-116,448	Jun 30, 2026	carried, not yet filed for the newest quarter
17	GEODE CAPITAL MANAGEMENT, LLC 13F CIK 1214717 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	591,849	0.71%	-6,272	Jun 30, 2026	carried, not yet filed for the newest quarter
18	VANGUARD EXTENDED MARKET INDEX FUND Fund S000002841 · Registered fund · Jun 30, 2026 VANGUARD INDEX FUNDS, not summed	558,775	0.67%	+20,958	Jun 30, 2026	VANGUARD INDEX FUNDS, not summed
19	Woodline Partners LP 13F CIK 1784547 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	523,999	0.63%	+523,999	Jun 30, 2026	carried, not yet filed for the newest quarter
20	Wadhane Jitendra Insider CIK 1941706 · Mar 24, 2026 Prin Fin & Acct Officer, issuer-wide	512,882	0.61%	+114,461	Mar 24, 2026	Prin Fin & Acct Officer, issuer-wide
21	683 Capital Management, LLC 13F CIK 1404574 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	459,367	0.55%	-436,896	Jun 30, 2026	carried, not yet filed for the newest quarter
22	JACOBS LEVY EQUITY MANAGEMENT, INC 13F CIK 884414 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	428,606	0.51%	-32,391	Jun 30, 2026	carried, not yet filed for the newest quarter
23	Ridgeback Capital Investments L.P. 13G CIK 1423994 · Unknown · Dec 31, 2024 Rule 13d-1(c), passive investor	359,231	0.43%	-3,985,997	Dec 31, 2024	Rule 13d-1(c), passive investor
24	Longaeva Partners L.P. 13F CIK 2054122 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	353,582	0.42%	-149,632	Jun 30, 2026	carried, not yet filed for the newest quarter
25	Decheng Capital LLC 13F CIK 2010850 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	326,810	0.39%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
26	VANGUARD FIDUCIARY TRUST CO 13F CIK 933478 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	302,986	0.36%	+2,089	Jun 30, 2026	carried, not yet filed for the newest quarter
27	JANE STREET GROUP, LLC 13F CIK 1595888 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	290,090	0.35%	-14,369	Jun 30, 2026	carried, not yet filed for the newest quarter
28	STATE STREET CORP 13F CIK 93751 · Bank · Jun 30, 2026 carried, not yet filed for the newest quarter	248,837	0.30%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
29	MILLENNIUM MANAGEMENT LLC 13F CIK 1273087 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	233,004	0.28%	-164,621	Jun 30, 2026	carried, not yet filed for the newest quarter
30	UBS Group AG 13F CIK 1610520 · Bank · Jun 30, 2026 carried, not yet filed for the newest quarter	155,217	0.19%	-98,907	Jun 30, 2026	carried, not yet filed for the newest quarter
31	Bank of New York Mellon Corp 13F CIK 1390777 · Bank · Jun 30, 2026 carried, not yet filed for the newest quarter	133,996	0.16%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
32	ACADIAN ASSET MANAGEMENT LLC 13F CIK 916542 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	126,793	0.15%	-17,463	Jun 30, 2026	carried, not yet filed for the newest quarter
33	NORTHERN TRUST CORP 13F CIK 73124 · Bank · Jun 30, 2026 carried, not yet filed for the newest quarter	123,959	0.15%	+22,011	Jun 30, 2026	carried, not yet filed for the newest quarter
34	NewEdge Wealth, LLC 13F CIK 1861796 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	116,006	0.14%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
35	XTX Topco Ltd 13F CIK 1828301 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	110,939	0.13%	-89,157	Jun 30, 2026	carried, not yet filed for the newest quarter
36	TWO SIGMA INVESTMENTS, LP 13F CIK 1179392 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	83,961	0.10%	+10,661	Jun 30, 2026	carried, not yet filed for the newest quarter
37	HUMPHREY RACHEL Insider CIK 1579781 · Apr 21, 2025 Director, issuer-wide	81,309	0.10%	-15,496	Apr 21, 2025	Director, issuer-wide
38	BRIDGEWAY CAPITAL MANAGEMENT, LLC 13F CIK 1107261 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	81,260	0.10%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
38.1	Ultra-Small Company Market Fund Fund S000004424 · Registered fund · Jun 30, 2026 Bridgeway Funds, Inc., not summed	70,060	0.08%	0	Jun 30, 2026	Bridgeway Funds, Inc., not summed
39	BANK OF AMERICA CORP /DE/ 13F CIK 70858 · Bank · Jun 30, 2026 carried, not yet filed for the newest quarter	80,464	0.10%	+63,657	Jun 30, 2026	carried, not yet filed for the newest quarter
40	STIFEL FINANCIAL CORP 13F CIK 720672 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	70,437	0.08%	+19,900	Jun 30, 2026	carried, not yet filed for the newest quarter
41	Cable Car Capital, LP 13F CIK 1699575 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	61,606	0.07%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
42	MYDA Advisors LLC 13F CIK 1589689 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	50,000	0.06%	+50,000	Jun 30, 2026	carried, not yet filed for the newest quarter
43	Qube Research & Technologies Ltd 13F CIK 1729829 · Exempt reporting adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	49,932	0.06%	+38,646	Jun 30, 2026	carried, not yet filed for the newest quarter
44	UNIVERSITY OF CHICAGO 13F CIK 314957 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	48,731	0.06%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
45	CITADEL ADVISORS LLC 13F CIK 1423053 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	47,317	0.06%	-13,932	Jun 30, 2026	carried, not yet filed for the newest quarter
46	Quadrature Capital Ltd 13F CIK 1651424 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	47,067	0.06%	+47,067	Jun 30, 2026	carried, not yet filed for the newest quarter
47	GOLDMAN SACHS GROUP INC 13F CIK 886982 · Holding company · Jun 30, 2026 carried, not yet filed for the newest quarter	45,900	0.06%	-1,020	Jun 30, 2026	carried, not yet filed for the newest quarter
48	Verdad Advisers, LP 13F CIK 1812822 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	44,899	0.05%	+44,899	Jun 30, 2026	carried, not yet filed for the newest quarter
49	LPL Financial LLC 13F CIK 1403438 · Broker-dealer · Jun 30, 2026 carried, not yet filed for the newest quarter	43,554	0.05%	+10,000	Jun 30, 2026	carried, not yet filed for the newest quarter
50	COMMONWEALTH EQUITY SERVICES, LLC 13F CIK 312272 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	42,455	0.05%	+7,700	Jun 30, 2026	carried, not yet filed for the newest quarter

Shares are restated onto today's split basis. Change compares each row with the same holder's previous filing in the same source; a dash means there is none to compare. Nested 13D/G, insider and fund rows are not summed, since a 13F report already holds them.

Showing 1–50 of 101 holders

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Key facts CIK 1782223 CUSIP 747324101 13F (30d) 9 filings 9 filers Visit website Investor relations