BAKER BROS. ADVISORS LP

Position in DNLI — Denali Therapeutics Inc.

CIK 1263508 NEW YORK, NY

Position in DNLI

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$96,047,121

+$24,398,577 QoQ

Shares Held

3,734,336

+0.1% QoQ

Ownership

2.34%

of shares outstanding

% of Portfolio

0.48%

of 13F equity value

Holder Rank

#12

of 290 holders

Holding Since

Mar 2020

26 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

BAKER BROS. ADVISORS LP holds $18,875,393,772 across 78 Biotechnology names. DNLI ranks #25 (0.5% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	INCY	Incyte Corp	30,762,330	$3,487,217,728
2	ONC	BeOne Medicines Ltd.	8,801,567	$2,508,182,547
3	RVMD	Revolution Medicines, Inc.	11,443,357	$2,143,111,898
4	MDGL	Madrigal Pharmaceuticals, Inc.	2,143,131	$1,150,754,190
5	ACAD	Acadia Pharmaceuticals Inc	42,912,904	$1,085,696,471
6	KYMR	Kymera Therapeutics, Inc.	8,657,242	$992,725,940
7	INSM	INSMED Inc	8,796,111	$937,841,354
8	CELC	Celcuity Inc.	7,915,792	$828,150,159

26 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$96,047,121	3,734,336	+0.1%	Shares	Sole	2026-08-14
2026-03-31	$71,648,544	3,731,695	0.0%	Shares	Sole	2026-05-15
2025-12-31	$61,610,284	3,731,695	0.0%	Shares	Sole	2026-02-17
2025-09-30	$54,184,211	3,731,695	0.0%	Shares	Sole	2025-11-14
2025-06-30	$52,206,413	3,731,695	0.0%	Shares	Sole	2025-08-14
2025-03-31	$50,732,393	3,731,695	0.0%	Shares	Sole	2025-05-15
2024-12-31	$76,051,944	3,731,695	0.0%	Shares	Sole	2025-02-14
2024-09-30	$108,704,275	3,731,695	0.0%	Shares	Sole	2024-11-14
2024-06-30	$86,649,957	3,731,695	0.0%	Shares	Sole	2024-08-14
2024-03-31	$76,574,381	3,731,695	+43.1%	Shares	Sole	2024-05-15
2023-12-31	$55,950,426	2,607,196	+13.8%	Shares	Sole	2024-02-14
2023-09-30	$47,284,021	2,292,003	+57.5%	Shares	Sole	2023-11-14
2023-06-30	$42,946,552	1,455,322	+33.7%	Shares	Sole	2023-08-14
2023-03-31	$25,084,523	1,088,738	0.0%	Shares	Sole	2023-05-15
2022-12-31	$30,277,803	1,088,738	+84.9%	Shares	Sole	2023-02-14
2022-09-30	$18,068,369	588,738	0.0%	Shares	Sole	2022-11-14
2022-06-30	$17,326,559	588,738	+563.5%	Shares	Sole	2022-08-15
2022-03-31	$2,854,701	88,738	0.0%	Shares	Sole	2022-05-16
2021-12-31	$3,957,714	88,738	0.0%	Shares	Sole	2022-02-14
2021-09-30	$4,476,832	88,738	0.0%	Shares	Sole	2021-11-15
2021-06-30	$6,960,608	88,738	0.0%	Shares	Sole	2021-08-16
2021-03-31	$5,066,939	88,738	0.0%	Shares	Sole	2021-05-17
2020-12-31	$7,432,694	88,738	-10.7%	Shares	Sole	2021-02-16
2020-09-30	$3,561,502	99,400	-5.2%	Shares	Sole	2020-11-16
2020-06-30	$2,536,482	104,900	0.0%	Shares	Sole	2020-08-14
2020-03-31	$1,836,799	104,900	—	Shares	Sole	2020-05-15
No filing history on record for this holder in this stock.