CHARLES SCHWAB INVESTMENT MANAGEMENT INC

Position in DNLI — Denali Therapeutics Inc.

CIK 884546 SAN FRANCISCO, CA

Position in DNLI

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$23,182,060

+$3,362,218 QoQ

Shares Held

1,207,399

+0.6% QoQ

Ownership

0.761%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Mar 2020

25 quarters on record

Voting authority Sole 99.99610733485783.ToString("F0")% Shared 0.ToString("F0")% None 0.0038926651421775237.ToString("F0")%

Healthcare · as of Mar 31, 2026

CHARLES SCHWAB INVESTMENT MANAGEMENT INC holds $6,181,979,796 across 287 Biotechnology names. DNLI ranks #55 (0.4% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	VRTX	Vertex Pharmaceuticals Inc / Ma	1,920,871	$857,745,736
2	REGN	Regeneron Pharmaceuticals, Inc.	804,508	$621,595,061
3	MRNA	Moderna, Inc.	4,734,356	$240,505,284
4	ALNY	Alnylam Pharmaceuticals, Inc.	673,356	$222,793,299
5	INSM	INSMED Inc	1,069,390	$174,866,652
6	RVMD	Revolution Medicines, Inc.	1,735,476	$168,775,041
7	INCY	Incyte Corp	1,729,102	$162,743,080
8	BBIO	BridgeBio Pharma, Inc.	1,976,094	$146,744,740

25 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$23,182,060	1,207,399	+0.6%	Shares	Sole	2026-05-15
2025-12-31	$19,819,842	1,200,475	+4.3%	Shares	Sole	2026-02-13
2025-09-30	$16,718,095	1,151,384	+9.0%	Shares	Sole	2025-11-10
2025-06-30	$14,773,705	1,056,019	+4.6%	Shares	Sole	2025-08-12
2025-03-31	$13,729,536	1,009,896	-1.8%	Shares	Sole	2025-09-15
2024-12-31	$20,960,055	1,028,462	+1.2%	Shares	Sole	2025-02-06
2024-09-30	$29,590,545	1,015,810	-4.1%	Shares	Sole	2024-11-12
2024-06-30	$24,597,038	1,059,304	+1.8%	Shares	Sole	2024-08-12
2024-03-31	$21,362,530	1,041,059	+3.4%	Shares	Sole	2024-05-09
2023-12-31	$21,610,155	1,006,997	+2.6%	Shares	Sole	2024-02-06
2023-09-30	$20,239,247	981,059	+13.1%	Shares	Sole	2023-11-08
2023-06-30	$25,603,790	867,631	+3.7%	Shares	Sole	2023-08-10
2023-03-31	$19,268,997	836,328	-0.0%	Shares	Sole	2023-05-12
2022-12-31	$23,267,876	836,673	+14.5%	Shares	Sole	2023-02-13
2022-09-30	$22,430,707	730,880	-0.1%	Shares	Sole	2022-11-14
2022-06-30	$21,528,692	731,522	+3.9%	Shares	Sole	2022-08-15
2022-03-31	$22,655,754	704,251	-1.8%	Shares	Sole	2022-05-13
2021-12-31	$31,986,674	717,190	+1.9%	Shares	Sole	2022-02-11
2021-09-30	$35,504,288	703,752	+9.9%	Shares	Sole	2021-11-16
2021-06-30	$50,219,954	640,234	+13.2%	Shares	Sole	2021-08-16
2021-03-31	$32,290,963	565,516	+14.7%	Shares	Sole	2021-05-17
2020-12-31	$41,310,264	493,198	+1.4%	Shares	Sole	2021-02-16
2020-09-30	$17,429,145	486,440	+3.2%	Shares	Sole	2020-11-13
2020-06-30	$11,394,728	471,246	+12.6%	Shares	Sole	2020-08-20
2020-03-31	$7,330,946	418,672	—	Shares	Sole	2020-05-15
No filing history on record for this holder in this stock.