JANE STREET GROUP, LLC

CIK

1595888

City

NEW YORK

State / Country

Stock

AGIO — Agios Pharmaceuticals, Inc.

Top Portfolio Positions

3,962 positions · $676,020,615,977 total · as of Mar 31, 2026

Ticker	Company	Shares	Value (USD)	% of Portfolio
SPY	Spdr S&P 500 ETF Trust	199,908,899	$130,008,753,375	19.23%
QQQ	Invesco Qqq Trust, Series 1	72,961,946	$42,112,175,991	6.23%
TSLA	Tesla, Inc. Consumer Cyclical	96,307,904	$35,802,463,311	5.30%
NVDA	Nvidia Corp Technology	186,634,816	$32,549,111,909	4.81%
GLD	Spdr Gold Trust	75,600,043	$32,529,942,501	4.81%
META	Meta Platforms, Inc. Communication Services	35,584,342	$20,358,869,587	3.01%
MU	Micron Technology Inc Technology	44,692,337	$15,098,859,131	2.23%
MSFT	Microsoft Corp Technology	39,450,469	$14,603,380,108	2.16%
AMZN	Amazon Com Inc Consumer Cyclical	67,664,445	$14,092,473,959	2.08%
AAPL	Apple Inc. Technology	49,649,392	$12,600,519,193	1.86%

Portfolio Trend

23 quarters · across all stocks

Holdings in AGIO

Compact Export CSV

Shares Held

Position Value (USD)

42 quarters on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$23,181,668	685,240	+1295.6%	Shares	Defined	2026-05-12
2026-03-31	$1,661,053	49,100	-54.2%	Call	Defined	2026-05-12
2026-03-31	$3,623,193	107,100	+219.8%	Put	Defined	2026-05-12
2025-06-30	$1,113,843	33,489	-73.4%	Shares	Defined	2025-08-14
2025-03-31	$3,694,846	126,104	-41.1%	Shares	Defined	2025-05-19
2024-12-31	$7,032,926	214,027	+2478.6%	Shares	Defined	2025-02-14
2024-09-30	$368,769	8,300	-93.4%	Call	Defined	2024-11-15
2024-09-30	$5,620,616	126,505	-28.5%	Shares	Defined	2024-11-15
2024-06-30	$7,624,262	176,815	+42.0%	Shares	Defined	2024-08-15
2024-03-31	$3,641,402	124,535	+27.0%	Shares	Defined	2024-05-16
2023-12-31	$2,182,926	98,021	+78.1%	Shares	Defined	2024-02-15
2023-09-30	$1,361,868	55,025	-21.0%	Shares	Defined	2023-11-15
2023-06-30	$1,971,637	69,620	+172.3%	Shares	Defined	2023-08-14
2023-03-31	$587,365	25,571	-13.9%	Shares	Defined	2023-05-16
2022-12-31	$834,424	29,716	-41.1%	Shares	Defined	2023-02-15
2022-06-30	$1,119,119	50,479	+560.9%	Shares	Defined	2022-08-16
2022-03-31	$222,341	7,638	-67.9%	Shares	Defined	2022-05-17
2022-03-31	$692,818	23,800	+8.2%	Call	Defined	2022-05-17
2022-03-31	$640,420	22,000	-81.8%	Put	Defined	2022-05-17
2021-12-31	$3,967,409	120,700	+43.5%	Call	Defined	2022-02-15
2021-12-31	$2,764,367	84,100	+23.5%	Put	Defined	2022-02-15
2021-12-31	$2,238,414	68,099	-23.5%	Shares	Defined	2022-02-15
2021-09-30	$4,107,350	89,000	-18.7%	Put	Defined	2021-11-16
2021-09-30	$5,053,425	109,500	+63.1%	Call	Defined	2021-11-16
2021-09-30	$3,098,741	67,145	-50.3%	Shares	Defined	2021-11-16
2021-06-30	$7,439,850	135,000	+40.8%	Put	Defined	2021-08-16
2021-06-30	$5,285,049	95,900	+209.6%	Call	Defined	2021-08-16
2021-06-30	$1,707,031	30,975	-48.3%	Shares	Defined	2021-08-16
2021-03-31	$3,093,906	59,913	-15.9%	Shares	Defined	2021-05-18
2021-03-31	$3,676,768	71,200	+2.2%	Call	Defined	2021-05-18
2021-03-31	$3,599,308	69,700	+51.0%	Put	Defined	2021-05-18
2020-12-31	$2,000,416	46,167	-68.2%	Shares	Defined	2021-02-17
2020-12-31	$6,300,182	145,400	+35.3%	Put	Defined	2021-02-17
2020-12-31	$4,657,975	107,500	+73.5%	Call	Defined	2021-02-17
2020-09-30	$2,168,460	61,956	-8.1%	Shares	Defined	2020-11-17
2020-09-30	$2,359,000	67,400	+47.5%	Call	Defined	2020-11-17
2020-09-30	$1,599,500	45,700	+294.0%	Put	Defined	2020-11-17
2020-06-30	$620,368	11,600	+3.4%	Put	Defined	2020-08-17
2020-06-30	$599,884	11,217	-91.6%	Shares	Defined	2020-08-17
2020-06-30	$7,128,884	133,300	+1348.9%	Call	Defined	2020-08-17
2020-03-31	$326,416	9,200	+33.3%	Call	Defined	2020-05-15
2020-03-31	$244,812	6,900	—	Put	Defined	2020-05-15
No 13F history on record for this holder in this stock.