JANE STREET GROUP, LLC

Position in AGIO — Agios Pharmaceuticals, Inc.

CIK 1595888 NEW YORK, NY

Back to AGIO Full portfolio

Position in AGIO

as of Mar 31, 2026 · filed May 12, 2026 Compact

Position Value

$23,181,668

-$7,333,312 QoQ

Shares Held

685,240

-38.9% QoQ

Ownership

1.15%

of shares outstanding

% of Portfolio

0.03%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Mar 2020

24 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Common Shares in AGIO Over Time

Shares Held

Position Value (USD)

Derivatives in AGIO

reported options exposure · as of Mar 31, 2026

CallValue

$1,661,053

CallShares

49,100

PutValue

$3,623,193

PutShares

107,100

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Mar 31, 2026

JANE STREET GROUP, LLC holds $1,248,975,671 across 317 Biotechnology names. AGIO ranks #14 (1.9% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	BBIO	BridgeBio Pharma, Inc.	1,757,672	$130,524,721
2	RPRX	Royalty Pharma plc	2,400,382	$115,146,324
3	TGTX	Tg Therapeutics, Inc.	2,041,669	$67,824,242
4	VRTX	Vertex Pharmaceuticals Inc / Ma	122,946	$54,900,305
5	HALO	Halozyme Therapeutics, Inc.	831,707	$53,753,223
6	EXEL	Exelixis, Inc.	1,087,030	$46,622,715
7	JAZZ	Jazz Pharmaceuticals plc	223,615	$42,274,415
8	BNTX	BioNTech SE	336,757	$29,930,962

All Filings in AGIO

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48 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$1,661,053	49,100	-54.2%	Call	Defined	2026-05-12
2026-03-31	$3,623,193	107,100	-84.4%	Put	Defined	2026-05-12
2026-03-31	$23,181,668	685,240	+288.0%	Shares	Defined	2026-05-12
2025-12-31	$4,807,052	176,600	-84.2%	Call	Defined	2026-02-12
2025-12-31	$30,514,980	1,121,050	+640.0%	Shares	Defined	2026-02-12
2025-12-31	$4,123,830	151,500	+161.2%	Put	Defined	2026-02-12
2025-09-30	$2,328,120	58,000	-85.3%	Call	Defined	2025-11-14
2025-09-30	$15,860,116	395,120	+3851.2%	Shares	Defined	2025-11-14
2025-09-30	$401,400	10,000	-70.1%	Put	Defined	2025-11-14
2025-06-30	$1,113,843	33,489	-73.4%	Shares	Defined	2025-08-14
2025-03-31	$3,694,846	126,104	-41.1%	Shares	Defined	2025-05-19
2024-12-31	$7,032,926	214,027	+2478.6%	Shares	Defined	2025-02-14
2024-09-30	$368,769	8,300	-93.4%	Call	Defined	2024-11-15
2024-09-30	$5,620,616	126,505	-28.5%	Shares	Defined	2024-11-15
2024-06-30	$7,624,262	176,815	+42.0%	Shares	Defined	2024-08-15
2024-03-31	$3,641,402	124,535	+27.0%	Shares	Defined	2024-05-16
2023-12-31	$2,182,926	98,021	+78.1%	Shares	Defined	2024-02-15
2023-09-30	$1,361,868	55,025	-21.0%	Shares	Defined	2023-11-15
2023-06-30	$1,971,637	69,620	+172.3%	Shares	Defined	2023-08-14
2023-03-31	$587,365	25,571	-13.9%	Shares	Defined	2023-05-16
2022-12-31	$834,424	29,716	-41.1%	Shares	Defined	2023-02-15
2022-06-30	$1,119,119	50,479	+560.9%	Shares	Defined	2022-08-16
2022-03-31	$222,341	7,638	-67.9%	Shares	Defined	2022-05-17
2022-03-31	$692,818	23,800	+8.2%	Call	Defined	2022-05-17
2022-03-31	$640,420	22,000	-81.8%	Put	Defined	2022-05-17
2021-12-31	$3,967,409	120,700	+43.5%	Call	Defined	2022-02-15
2021-12-31	$2,764,367	84,100	+23.5%	Put	Defined	2022-02-15
2021-12-31	$2,238,414	68,099	-23.5%	Shares	Defined	2022-02-15
2021-09-30	$4,107,350	89,000	-18.7%	Put	Defined	2021-11-16
2021-09-30	$5,053,425	109,500	+63.1%	Call	Defined	2021-11-16
2021-09-30	$3,098,741	67,145	-50.3%	Shares	Defined	2021-11-16
2021-06-30	$7,439,850	135,000	+40.8%	Put	Defined	2021-08-16
2021-06-30	$5,285,049	95,900	+209.6%	Call	Defined	2021-08-16
2021-06-30	$1,707,031	30,975	-48.3%	Shares	Defined	2021-08-16
2021-03-31	$3,093,906	59,913	-15.9%	Shares	Defined	2021-05-18
2021-03-31	$3,676,768	71,200	+2.2%	Call	Defined	2021-05-18
2021-03-31	$3,599,308	69,700	+51.0%	Put	Defined	2021-05-18
2020-12-31	$2,000,416	46,167	-68.2%	Shares	Defined	2021-02-17
2020-12-31	$6,300,182	145,400	+35.3%	Put	Defined	2021-02-17
2020-12-31	$4,657,975	107,500	+73.5%	Call	Defined	2021-02-17
2020-09-30	$2,168,460	61,956	-8.1%	Shares	Defined	2020-11-17
2020-09-30	$2,359,000	67,400	+47.5%	Call	Defined	2020-11-17
2020-09-30	$1,599,500	45,700	+294.0%	Put	Defined	2020-11-17
2020-06-30	$620,368	11,600	+3.4%	Put	Defined	2020-08-17
2020-06-30	$599,884	11,217	-91.6%	Shares	Defined	2020-08-17
2020-06-30	$7,128,884	133,300	+1348.9%	Call	Defined	2020-08-17
2020-03-31	$326,416	9,200	+33.3%	Call	Defined	2020-05-15
2020-03-31	$244,812	6,900	—	Put	Defined	2020-05-15
No filing history on record for this holder in this stock.