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AGIO · Agios Pharmaceuticals, Inc.

Track AGIO — free
$33.24 -0.01 (-0.03%)
Market Cap
$2.02B
Shares
59.70M
Volume · Oct 1 117.09K Avg daily vol (3M) 1.06M

Price & Indicators

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20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$33.25 Open$33.67 Day$33.20–34.06 52W close$22.34–45.49 Avg vol 30d936K Short int7.6M · 12.7% float · 9.5d Short vol64% Last earningsJul 30, 2026 DataJan 2020–Sep 2026 Filing10-Q · Jul 30

Up next

Next earnings call
Oct 27, 2026 Est · unconfirmed · in 4 wks
filed Jul 30, 2026
call held Jul 30, 2026

Metrics snapshot

Useful current figures from the complete screener profile.

Revenue (TTM)
$98.34M
Trailing 12 months
Net income (TTM)
−$411.29M
Trailing 12 months
Revenue growth YoY
+259.3%
Year over year
Operating margin
-466.8%
Trailing 12 months
P / E (TTM)
—
Trailing earnings
FCF yield
-18.1%
TTM · current market cap
Return on invested capital
—
Trailing 12 months
Net cash
$99.65M
Latest balance sheet
Dividend yield
—
Trailing 12 months
Shares change YoY
+2.7%
Year over year · more shares
Price change (1Y)
-17.2%
Trailing year
Short interest
12.7%
Latest settlement · 9.5 days to cover
View all 115 metrics

Equibles Rating

blended score · not investment advice
Overall
Sell
SellHoldBuy
Technical Neutral Momentum Weak Sentiment Neutral Fundamentals Weak Quant / Vol Very High
Market backdrop VIX 16.3 · calm Equity put/call 0.53
Technical
price trend
Neutral
50 / 200-day cross No cross
Price vs 200-day avg +7%
above
Price vs 50-day avg −1%
below
RSI (14) 48
neutral
MACD trend Negative
52-week position 47%
mid-range
Volume (OBV) Confirms
volume backs price
Momentum
relative strength
Weak
1-month return −3%
trailing
6-month return +1%
trailing
YTD return +22%
this year
Relative strength −11%
vs S&P · 6-mo
Sentiment
smart money
Neutral
Trend (MA cross) No cross
50d $34 › 200d $31 — 50d above 200d
Institutional flow Accumulating
+1% holders QoQ · +36 funds added
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
12.66% of float · ▲ +0.3% MoM · 9.5 days cover
Volume signal Reversal watch
High volume on a down day — possible exhaustion
Institution breadth Multi-yr high
239 holders — near 3-yr high, broad support
Squeeze score 72
high risk · 0–100
Fundamentals
Weak
Revenue growth −38%
Y/Y
EPS growth −161%
Y/Y
Free cash flow $-377.3M
Buyback $415.5M
remaining
Quant / Vol
risk profile
Very High
Volatility 76%
annualized · 1-yr
Max drawdown −51%
past year
ATR 4.0%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Guidance & track record

Latest guidance · from the Earnings Call filed Dec 31, 2025
U.S. PK deficiency revenues · 2026 $45M – $50M

Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.

Technicals

trend & momentum for long-term holders Neutral
1 · 5 · 1
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
+7% Bullish
Price vs 50-day avg
−1% Neutral
RSI (14)
48 Neutral
MACD trend
Negative Bearish
52-week position
47% Neutral
Volume (OBV)
Confirms Neutral
Market signals — smart money & positioning
Bullish · 2 of 6
Trend (MA cross) No cross
50d $34 › 200d $31 — 50d above 200d
Institutional flow Accumulating
+1% holders QoQ · +36 funds added
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
12.66% of float · ▲ +0.3% MoM · 9.5 days cover
Volume signal Reversal watch
High volume on a down day — possible exhaustion
Institution breadth Multi-yr high
239 holders — near 3-yr high, broad support
Price context
position in its 52-week range
Range low $22 Now $33 · 47% Range high $45
vs 200-day avg +7% vs 50-day avg -1%

Illustrative technical + ownership context — a signal mix, not investment advice.

Key metrics

Earlier KPI extraction records exist, but do not meet the current evidence-completeness requirements. No current verified series is available. Earlier figures remain withheld until revalidated; this is not evidence that the company reports no KPIs.

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
AGIO
Agios Pharmaceuticals, Inc.
this stock
$2.02B +22.2% -38.5% — 12.7%
VRTX
Vertex Pharmaceuticals Inc / Ma
$133.37B +15.3% +46.2% 30.7 1.9%
REGN
Regeneron Pharmaceuticals, Inc.
$81.13B -1.8% +20.8% 19.5 2.5%
MRNA
Moderna, Inc.
$79.40B +553.0% +4.3% — 8.2%
CSLLY
Csl Ltd
$61.25B — — — 0.0%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Accumulating
Holders
239
% held
117.0%
Net QoQ
+2.7M sh
Top holder
BlackRock, Inc.
Held Float
View
Held by Funds
Fund positions
242
View
Short & Settlement
Short Interest Rising
Shares short
7.6M
Days to cover
9.5d
Change
+22.2K sh
View
Short Volume
Short vol %
64%
As of
Sep 30, 2026
Short Total
View
Fails to Deliver
FTD shares
94
Value
$3.2K
As of
Aug 17, 2026
View
Off-Exchange
Off-exchange %
46.8%
Week of
Aug 24, 2026
Off-exch Lit
View
Smart Money
Congressional Trades Buy
Member
Gilbert Cisneros
Amount
$1.0K–$15.0K
Traded
Mar 3, 2026
View
Financials
Financials
Revenue (FY)
$54.0M
Net income (FY)
$-412.8M
EPS diluted
$-7.12
View
Buybacks
Authorized · 2 programs
$1.8B
Remaining
$415.5M
Spent Remaining
View
Filings
SEC Filings
Latest
Investor Event Transcript
Filed
Sep 9, 2026
This year
10
View
Proposed Sales
Value
$914.3K
Shares
30.0K
Filed
Aug 4, 2026
View
Earnings & Events
Earnings Calls
Last call
Sep 9, 2026
View
Investor Relations
Latest news
Agios Reports Second Quarter 2026…
Published
Jul 30, 2026
View

Performance

5D 20D 120D MTD YTD
AGIO -2.8% -2.8% +1.0% -1.3% +22.2%
SPY -0.7% +0.1% +12.2% -0.6% +11.8%
vs SPY -2.1% -2.9% -11.2% -0.7% +10.3%

Capital returns

Buyback programs · 2 active · as of Jun 30, 2021
Authorized (total)
$1.80B
Spent (derived)
$1.38B
Remaining
$415.50M
Spent Remaining

Dividends per share over the trailing 365 days by ex-date · buyback figures as last reported in SEC filings ("spent" derived as authorized − remaining; when several programs run concurrently, authorized is their combined total per the newest filing) · components shown separately — trailing-year buyback spend isn't tracked, so no combined shareholder yield is derived.

Key facts CIK 1439222 CUSIP 00847X104 13F (30d) 6 filings 6 filers Visit website Investor relations