BARCLAYS PLC

CIK

312069

City

LONDON

State / Country

Stock

AGIO — Agios Pharmaceuticals, Inc.

Top Portfolio Positions

3,763 positions · $331,657,775,458 total · as of Mar 31, 2026

Ticker	Company	Shares	Value (USD)	% of Portfolio
MSFT	Microsoft Corp Technology	90,718,129	$33,581,129,808	10.13%
SPY	Spdr S&P 500 ETF Trust	50,435,151	$32,799,996,100	9.89%
NVDA	Nvidia Corp Technology	98,209,762	$17,127,782,490	5.16%
QQQ	Invesco Qqq Trust, Series 1	28,825,875	$16,637,718,531	5.02%
AAPL	Apple Inc. Technology	41,584,066	$10,553,620,108	3.18%
AMZN	Amazon Com Inc Consumer Cyclical	41,965,369	$8,740,127,398	2.64%
GOOGL	Alphabet Inc. Communication Services	27,728,578	$7,973,629,887	2.40%
META	Meta Platforms, Inc. Communication Services	12,417,494	$7,104,420,839	2.14%
AVGO	Broadcom Inc. Technology	20,117,836	$6,226,671,417	1.88%
TSLA	Tesla, Inc. Consumer Cyclical	13,762,733	$5,116,295,991	1.54%

Portfolio Trend

25 quarters · across all stocks

Holdings in AGIO

Compact Export CSV

Shares Held

Position Value (USD)

32 quarters on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$1,773,976	52,438	-83.6%	Shares	Defined	2026-05-15
2025-12-31	$8,719,980	320,352	+513.7%	Shares	Sole	2026-02-13
2025-12-31	$1,420,884	52,200	-75.8%	Call	Sole	2026-02-13
2025-09-30	$8,671,844	216,040	+19.6%	Shares	Sole	2026-03-31
2025-06-30	$6,010,212	180,704	+59.7%	Shares	Sole	2026-02-27
2025-03-31	$3,315,382	113,153	-7.1%	Shares	Sole	2026-03-17
2024-12-31	$4,000,803	121,753	+278.1%	Shares	Sole	2026-03-19
2024-09-30	$1,430,646	32,200	-82.2%	Call	Sole	2026-03-31
2024-09-30	$8,015,927	180,417	+64.2%	Shares	Sole	2026-03-31
2024-06-30	$4,738,068	109,881	+241.2%	Shares	Sole	2026-03-23
2024-06-30	$1,388,464	32,200	+7.3%	Call	Sole	2026-03-23
2024-03-31	$877,200	30,000	0.0%	Call	Sole	2026-03-24
2024-03-31	$877,200	30,000	-56.7%	Put	Sole	2026-03-24
2024-03-31	$2,024,168	69,226	+15.4%	Shares	Sole	2026-03-24
2023-12-31	$1,336,200	60,000	0.0%	Put	Sole	2026-03-24
2023-12-31	$1,336,200	60,000	-61.2%	Call	Sole	2026-03-24
2023-12-31	$3,445,970	154,736	+27.9%	Shares	Sole	2026-03-24
2023-09-30	$2,994,947	121,008	-23.8%	Shares	Sole	2026-03-26
2023-06-30	$4,495,091	158,725	+65.6%	Shares	Sole	2026-03-27
2023-03-31	$2,201,192	95,829	-25.3%	Shares	Sole	2026-03-30
2022-12-31	$3,600,136	128,210	+34.3%	Shares	Sole	2026-03-30
2022-09-30	$2,700,739	95,500	+391.8%	Shares	Sole	2022-11-03
2022-06-30	$430,541	19,420	-70.5%	Shares	Sole	2022-08-12
2022-03-31	$1,917,766	65,880	-5.6%	Shares	Sole	2022-05-16
2021-12-31	$2,294,819	69,815	+164.2%	Shares	Sole	2022-02-23
2021-09-30	$1,219,467	26,424	-50.5%	Shares	Sole	2021-11-09
2021-06-30	$2,941,661	53,378	-42.4%	Shares	Sole	2021-08-13
2021-03-31	$4,782,844	92,619	-16.9%	Shares	Sole	2021-05-13
2020-12-31	$4,828,954	111,446	-2.8%	Shares	Sole	2021-02-11
2020-09-30	$4,014,465	114,699	+8.1%	Shares	Sole	2020-11-12
2020-06-30	$5,672,730	106,072	-3.6%	Shares	Sole	2020-08-12
2020-03-31	$3,903,118	110,009	—	Shares	Sole	2020-05-13
No 13F history on record for this holder in this stock.