MDGL · Madrigal Pharmaceuticals, Inc. · Holdings

$487.72 -8.73 (-1.76%) At close · Oct 7

Russell 1000 member Rebalance outlook locked

Market Cap

$11.27B

23.10M

Volume · Oct 7 256.25K Avg daily vol (3M) 292.09K

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP →

Some SEC filings for this period have not finished importing. Holder totals and changes may be incomplete; these filings remain queued for recovery.

The Sep 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out. Each fund's Change is measured against its own previous reported quarter, shown in the Reported column. Pick a completed quarter in the Quarter selector below to put every fund on one quarter and see the stock-wide activity breakdown.

Quarter:

Holders: 419

Total Value: $13,281,724,868

Total Shares: 24,735,503

Showing 1–100 of 439 holdings by value · page 1 of 5

Institutional Ownership Trend

27 quarters

Holder Concentration

Across 419 13F filers

Top Holder

8.7%

of institutional value

Top 5

37.4%

of institutional value

Top 10

54.9%

of institutional value

HHI

387

Broadly held

Showing 100 of 439

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

BAKER BROS. ADVISORS LP

$1,150,754,190

8.66%

2,143,131

RTW INVESTMENTS, LP

$1,070,510,234

8.06%

1,993,687

Jupiter Topco LLC

$1,039,588,355

7.83%

1,936,099

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JANUS HENDERSON INVESTORS UK Ltd	15,803	$8,485,420	0.8%	Defined
JANUS HENDERSON INVESTORS US LLC	1,895,240	$1,017,649,118	97.9%	Defined
Held directly	25,056	$13,453,817	1.3%	Defined

Avoro Capital Advisors LLC

$984,408,154

7.41%

1,833,333

PAULSON & CO. INC.

$719,523,739

5.42%

1,340,020

BlackRock, Inc.

$644,753,445

4.85%

1,200,770

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	31,112	$16,705,588	2.6%	Sole
BlackRock Investment Management (Australia) Ltd	31	$16,645	0.0%	Sole
BlackRock Asset Management Canada Ltd	1,952	$1,048,126	0.2%	Sole
BlackRock Investment Management, LLC	9,655	$5,184,252	0.8%	Sole
BLACKROCK ADVISORS LLC	52,127	$27,989,592	4.3%	Sole
BlackRock Fund Advisors	509,684	$273,674,823	42.4%	Sole
BlackRock Institutional Trust Company, N.A.	504,532	$270,908,457	42.0%	Sole
BlackRock Japan Co. Ltd	199	$106,853	0.0%	Sole
BlackRock Fund Managers Ltd.	2,758	$1,480,908	0.2%	Sole
BlackRock Investment Management (UK) Ltd.	9,618	$5,164,385	0.8%	Sole
BlackRock (Netherlands) B.V.	483	$259,346	0.0%	Sole
BlackRock Asset Management Ireland Ltd	37,780	$20,285,971	3.1%	Sole
BlackRock Advisors (UK) Ltd	284	$152,493	0.0%	Sole
BlackRock (Luxembourg) S.A.	915	$491,309	0.1%	Sole
BlackRock Life Ltd	55	$29,532	0.0%	Sole
BlackRock Asset Management Schweiz AG	2,497	$1,340,764	0.2%	Sole
Aperio Group, LLC	28,172	$15,126,955	2.3%	Sole
SpiderRock Advisors, LLC	8,916	$4,787,446	0.7%	Sole

VANGUARD CAPITAL MANAGEMENT LLC

$448,711,932

3.38%

835,668

WELLINGTON MANAGEMENT GROUP LLP

$443,367,129

3.34%

825,714

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wellington Management Company LLP	768,153	$412,459,753	93.0%	Defined
Wellington Managment Canada LLC	176	$94,503	0.0%	Defined
Wellington Management Singapore Pte. Ltd.	6,320	$3,393,524	0.8%	Defined
Wellington Management International Ltd	9,802	$5,263,183	1.2%	Defined
Wellington Trust Company, NA joint	38,628	$20,741,304	4.7%	Defined
Wellington Management Australia Pty Ltd	2,231	$1,197,935	0.3%	Defined
Wellington Management Europe GmbH	404	$216,927	0.0%	Defined

VANGUARD PORTFOLIO MANAGEMENT LLC

$419,750,460

3.16%

781,731

STATE STREET CORP

$283,003,256

2.13%

527,057

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	527,057	$283,003,256	100.0%	Defined

CITADEL ADVISORS LLC

$272,358,759

2.05%

507,233

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	110,819	$59,504,262	21.8%	Defined
Held directly	396,414	$212,854,497	78.2%	Defined

UBS Group AG

$215,697,109

1.62%

401,708

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	53,712	$28,840,658	13.4%	Defined
UBS AG	39,191	$21,043,607	9.8%	Defined
UBS Switzerland AG	26,496	$14,227,027	6.6%	Defined
UBS Securities LLC	282,309	$151,585,817	70.3%	Defined

GEODE CAPITAL MANAGEMENT, LLC

$201,291,815

1.52%

374,880

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	48,483	$26,032,946	12.9%	Defined
Held directly	326,397	$175,258,869	87.1%	Defined

FMR LLC

$191,262,125

1.44%

356,201

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	323,251	$173,569,624	90.7%	Defined
STRATEGIC ADVISERS LLC	167	$89,670	0.0%	Defined
Fidelity Institutional Asset Management Trust Co	27,290	$14,653,365	7.7%	Defined
FIAM LLC	5,493	$2,949,466	1.5%	Defined

WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC

$174,037,844

1.31%

324,123

Invesco Ltd.

$161,855,520

1.22%

301,435

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	273,824	$147,029,795	90.8%	Defined
Invesco Trust Co joint	7,305	$3,922,419	2.4%	Defined
Invesco Capital Management LLC	20,306	$10,903,306	6.7%	Defined

ARMISTICE CAPITAL, LLC

$154,641,600

1.16%

288,000

LORD, ABBETT & CO. LLC

$151,151,425

1.14%

281,500

GOLDMAN SACHS GROUP INC

$132,240,043

1.00%

246,280

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	121,502	$65,240,498	49.3%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	121,045	$64,995,112	49.1%	Defined
GOLDMAN SACHS INTERNATIONAL	1,057	$567,556	0.4%	Defined
GOLDMAN SACHS BANK AG	437	$234,647	0.2%	Defined
GOLDMAN SACHS WEALTH SERVICES, L.P.	1,378	$739,917	0.6%	Defined
Goldman Sachs Trust Company, N.A.	861	$462,313	0.3%	Defined

Polar Capital Holdings Plc

$131,162,924

0.99%

244,274

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Polar Capital LLP	244,274	$131,162,924	100.0%	Defined

AMERIPRISE FINANCIAL INC

$124,145,521

0.93%

231,205

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Columbia Management Investment Advisers, LLC joint	205,107	$110,132,203	88.7%	Defined
Ameriprise Trust Co	5,470	$2,937,116	2.4%	Defined
Ameriprise Financial Services, LLC	181	$97,187	0.1%	Defined
Ameriprise Bank, FSB	2	$1,073	0.0%	Defined
Columbia Threadneedle Management Ltd	20,445	$10,977,942	8.8%	Defined

NORGES BANK

$114,846,087

0.86%

213,886

Artisan Partners Limited Partnership

$112,869,574

0.85%

210,205

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$112,652,110

0.85%

209,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	209,800	$112,652,110	100.0%	Other

Pictet Asset Management Holding SA

$103,575,507

0.78%

192,896

JANE STREET GROUP, LLC

$102,847,939

0.77%

191,541

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	84,616	$45,434,561	44.2%	Defined
Jane Street Global Trading, LLC	106,925	$57,413,378	55.8%	Defined

ALLIANCEBERNSTEIN L.P.

$101,729,473

0.77%

189,458

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	189,458	$101,729,473	100.0%	Defined

PRICE T ROWE ASSOCIATES INC /MD/

$100,531,000

0.76%

187,226

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	20,098	$10,791,621	10.7%	Defined
Held directly	167,128	$89,739,379	89.3%	Sole

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$98,972,771

0.75%

184,324

TORONTO DOMINION BANK

$97,419,912

0.73%

181,432

Rock Springs Capital Management LP

$93,965,713

0.71%

174,999

Hood River Capital Management LLC

$90,789,653

0.68%

169,084

Holocene Advisors, LP

$82,112,541

0.62%

152,924

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$79,796,139

0.60%

148,610

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	148,610	$79,796,139	100.0%	Other

MORGAN STANLEY

$74,640,876

0.56%

139,009

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	728	$390,899	0.5%	Defined
MORGAN STANLEY & CO. LLC	11,469	$6,158,279	8.3%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	34,322	$18,429,197	24.7%	Defined
MORGAN STANLEY AIP GP LP	6,540	$3,511,653	4.7%	Defined
MORGAN STANLEY INVESTMENT MANAGEMENT INC	762	$409,155	0.5%	Defined
MORGAN STANLEY SMITH BARNEY LLC	58,994	$31,676,827	42.4%	Defined
Morgan Stanley Strategic Investments, Inc	1	$536	0.0%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	20,071	$10,777,123	14.4%	Defined
EATON VANCE MANAGEMENT	10	$5,369	0.0%	Defined
Calvert Research & Management	6,112	$3,281,838	4.4%	Defined

Point72 Asset Management, L.P.

$73,577,721

0.55%

137,029

BANK OF AMERICA CORP /DE/

$71,970,626

0.54%

134,036

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	36,116	$19,392,486	26.9%	Defined
MERRILL LYNCH, PIERCE, FENNER & SMITH INC.	1,471	$789,853	1.1%	Defined
BOFA SECURITIES, INC.	13,282	$7,131,769	9.9%	Defined
MERRILL LYNCH INTERNATIONAL	384	$206,188	0.3%	Defined
MANAGED ACCOUNT ADVISORS LLC joint	80,414	$43,178,296	60.0%	Defined
BofA Securities Europe SA	2,369	$1,272,034	1.8%	Defined

Bank of New York Mellon Corp

$69,008,806

0.52%

128,520

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BNY Mellon Trust of Delaware joint	97	$52,084	0.1%	Defined
Mellon Investments Corporation joint	31,618	$16,977,284	24.6%	Defined
BNY Mellon Securities Corporation	929	$498,826	0.7%	Defined
The Bank of New York Mellon	18,860	$10,126,877	14.7%	Defined
BNY Mellon, NA joint	6,846	$3,675,958	5.3%	Defined
BNY Mellon Advisors, Inc.	906	$486,476	0.7%	Defined
Newton Investment Management North America, LLC joint	69,262	$37,190,228	53.9%	Defined
Held directly	2	$1,073	0.0%	Defined

Woodline Partners LP

$67,601,468

0.51%

125,899

Assenagon Asset Management S.A.

$66,696,707

0.50%

124,214

VANGUARD FIDUCIARY TRUST CO

$65,283,991

0.49%

121,583

Caption Management, LLC

$63,091,625

0.48%

117,500

Erste Asset Management GmbH

$59,177,259

0.45%

110,210

Clearbridge Investments, LLC

$58,702,058

0.44%

109,325

D. E. Shaw & Co., Inc.

$57,829,515

0.44%

107,700

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	107,700	$57,829,515	100.0%	Defined

JANE STREET GROUP, LLC

$55,950,190

0.42%

104,200

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	104,200	$55,950,190	100.0%	Defined

MARSHALL WACE, LLP

$54,693,189

0.41%

101,859

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	101,859	$54,693,189	100.0%	Other

Fiera Capital Corp

$53,618,215

0.40%

99,857

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fiera Capital Inc.	97,766	$52,495,453	97.9%	Other
Held directly	2,091	$1,122,762	2.1%	Sole

AMERICAN CENTURY COMPANIES INC

$53,370,682

0.40%

99,396

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AMERICAN CENTURY INVESTMENT MANAGEMENT INC	99,396	$53,370,682	100.0%	Defined

NORTHERN TRUST CORP

$52,894,943

0.40%

98,510

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	87,260	$46,854,256	88.6%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	11,250	$6,040,687	11.4%	Defined

NEW YORK STATE COMMON RETIREMENT FUND

$50,872,253

0.38%

94,743

CITADEL ADVISORS LLC

$50,473,300

0.38%

94,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	94,000	$50,473,300	100.0%	Defined

WESTFIELD CAPITAL MANAGEMENT CO LP

$50,436,250

0.38%

93,931

683 Capital Management, LLC

$48,325,500

0.36%

90,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
683 Capital Partners, LP	90,000	$48,325,500	100.0%	Defined

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$47,520,075

0.36%

88,500

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	88,500	$47,520,075	100.0%	Other

CITADEL ADVISORS LLC

$46,660,955

0.35%

86,900

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	86,900	$46,660,955	100.0%	Defined

HRT FINANCIAL LP

$45,444,226

0.34%

84,634

DEUTSCHE BANK AG\

$45,058,694

0.34%

83,916

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Deutsche Bank Trust Co Americas	309	$165,917	0.4%	Defined
DWS Investment GmbH	76,111	$40,867,801	90.7%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC	3,738	$2,007,119	4.5%	Defined
DWS Investments UK Ltd	3,456	$1,855,699	4.1%	Defined
DWS International GmbH	302	$162,158	0.4%	Defined

MILLENNIUM MANAGEMENT LLC

$43,598,192

0.33%

81,196

ALKEON CAPITAL MANAGEMENT LLC

$42,955,999

0.32%

80,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
OPPENHEIMER ASSET MANAGEMENT INC.	13,126	$7,048,005	16.4%	Other
Held directly	66,874	$35,907,994	83.6%	Sole

Balyasny Asset Management L.P.

$42,424,955

0.32%

79,011

Driehaus Capital Management LLC

$41,932,573

0.32%

78,094

Candriam S.C.A.

$38,725,370

0.29%

72,121

Tri Locum Partners LP

$36,659,187

0.28%

68,273

Allspring Global Investments Holdings, LLC

$36,334,331

0.27%

67,668

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Allspring Funds Management, LLC reporting on behalf of Morgan Stanley Smith Barney, LLC	1,326	$711,995	2.0%	Other
Allspring Global Investments, LLC reporting on behalf of UBS ASSET MANAGEMENT AMERICAS INC	66,342	$35,622,336	98.0%	Defined

Caption Management, LLC

$35,277,615

0.27%

65,700

Vestal Point Capital, LP

$34,901,750

0.26%

65,000

VOYA INVESTMENT MANAGEMENT LLC

$32,862,413

0.25%

61,202

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Voya Investment Management Co. LLC joint	61,202	$32,862,413	100.0%	Defined

JANE STREET GROUP, LLC

$31,733,745

0.24%

59,100

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	59,100	$31,733,745	100.0%	Defined

BNP PARIBAS ARBITRAGE, SA

$31,142,026

0.23%

57,998

Jones Hill Capital LP

$28,214,037

0.21%

52,545

EULAV Asset Management

$27,921,400

0.21%

52,000

SCHRODER INVESTMENT MANAGEMENT GROUP

$27,722,728

0.21%

51,630

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Schroder Investment Management Limited	51,519	$27,663,127	99.8%	Sole
Schroder Investment Management North America Inc.	111	$59,601	0.2%	Sole

Russell Investments Group, Ltd.

$26,468,409

0.20%

49,294

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	27,695	$14,870,829	56.2%	Defined
Russell Investments Canada Limited	26	$13,960	0.1%	Defined
Russell Investments Capital, LLC	12,405	$6,660,864	25.2%	Defined
Russell Investments France SAS	2,484	$1,333,783	5.0%	Defined
Russell Investments Limited	34	$18,256	0.1%	Defined
Russell Investments Trust Company joint	6,650	$3,570,717	13.5%	Other

RENAISSANCE TECHNOLOGIES LLC

$24,668,556

0.19%

45,942

Affinity Asset Advisors, LLC

$21,478,000

0.16%

40,000

CITIGROUP INC

$20,004,071

0.15%

37,255

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citibank, N.A. joint	2	$1,073	0.0%	Defined
Citigroup Financial Products Inc. joint	37,253	$20,002,998	100.0%	Defined

MILLENNIUM MANAGEMENT LLC

$19,330,200

0.15%

36,000

D. E. Shaw & Co., Inc.

$18,831,372

0.14%

35,071

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	21,983	$11,803,771	62.7%	Defined
D. E. Shaw Investment Management, L.L.C. joint	13,088	$7,027,601	37.3%	Defined

Mirae Asset Global Investments Co., Ltd.

$17,944,868

0.14%

33,420

Nuveen, LLC

$17,521,214

0.13%

32,631

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	6,701	$3,598,101	20.5%	Defined
TIAA CREF INVESTMENT MANAGEMENT LLC joint	457	$245,386	1.4%	Defined
TEACHERS ADVISORS, LLC joint	25,473	$13,677,727	78.1%	Defined

SEGALL BRYANT & HAMILL, LLC

$17,420,805

0.13%

32,444

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NEW YORK LIFE INVESTMENT MANAGEMENT LLC	32,444	$17,420,805	100.0%	Sole

UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC

$17,398,786

0.13%

32,403

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Group AG	7,536	$4,046,455	23.3%	Defined
UBS Asset Management Switzerland AG	21,412	$11,497,172	66.1%	Defined
UBS Asset Management (UK) Ltd.	1,697	$911,202	5.2%	Defined
Held directly	1,758	$943,957	5.4%	Defined

BNP PARIBAS ASSET MANAGEMENT Holding S.A.

$17,181,325

0.13%

31,998

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BNP PARIBAS ASSET MANAGEMENT Europe	233	$125,109	0.7%	Defined
AXA INVESTMENT MANAGERS UK LIMITED	31,765	$17,056,216	99.3%	Defined

GROUPAMA ASSET MANAGMENT

$16,613,769

0.13%

30,941

Swiss National Bank

$16,076,283

0.12%

29,940

JPMORGAN CHASE & CO

$15,825,523

0.12%

29,473

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
J.P. Morgan Trust Co of Delaware	163	$87,522	0.6%	Other
JPMorgan Chase Bank, N.A.	1,404	$753,877	4.8%	Defined
J.P. Morgan Investment Management Inc.	26,952	$14,471,876	91.4%	Defined
J.P. Morgan Securities LLC	329	$176,656	1.1%	Defined
J.P. Morgan Securities plc	36	$19,330	0.1%	Defined
55I, LLC	20	$10,738	0.1%	Other
J.P. Morgan SE	569	$305,524	1.9%	Defined

PFM Health Sciences, LP

$15,739,615

0.12%

29,313

CANADA PENSION PLAN INVESTMENT BOARD

$15,614,506

0.12%

29,080

Rockefeller Capital Management L.P.

$15,579,603

0.12%

29,015

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ROCKEFELLER & CO. LLC	39	$20,941	0.1%	Defined
ROCKEFELLER TRUST COMPANY, N.A.	210	$112,759	0.7%	Defined
ROCKEFELLER FINANCIAL LLC	28,766	$15,445,903	99.1%	Defined

GILDER GAGNON HOWE & CO LLC

$15,342,272

0.12%

28,573

WELLS FARGO & COMPANY/MN

$14,248,503

0.11%

26,536

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	891	$478,422	3.4%	Defined
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC	3,334	$1,790,191	12.6%	Defined
WELLS FARGO CLEARING SERVICES, LLC	22,288	$11,967,541	84.0%	Defined
WELLS FARGO INVESTMENT INSTITUTE, INC.	23	$12,349	0.1%	Defined

SEI INVESTMENTS CO

$13,867,269

0.10%

25,826

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SEI INVESTMENTS MANAGEMENT CORP	2,745	$1,473,927	10.6%	Sole
SEI TRUST CO	23,081	$12,393,342	89.4%	Sole

Integral Health Asset Management, LLC

$13,423,750

0.10%

25,000

California Public Employees Retirement System

$13,035,535

0.10%

24,277

WCM INVESTMENT MANAGEMENT, LLC

$12,341,795

0.09%

22,985

Susquehanna Portfolio Strategies, LLC

$11,814,510

0.09%

22,003

Tao Capital Management LP

$11,275,950

0.08%

21,000

HSBC HOLDINGS PLC

$10,867,866

0.08%

20,240

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
HSBC Bank USA, N.A.	8	$4,295	0.0%	Defined
HSBC GLOBAL ASSET MANAGEMENT (FRANCE)	20,172	$10,831,355	99.7%	Defined
HSBC BANK PLC	33	$17,719	0.2%	Defined
HSBC SECURITIES USA INC	27	$14,497	0.1%	Defined

FIRST TRUST ADVISORS LP

$10,645,570

0.08%

19,826

Key facts CIK 1157601 CUSIP 558868105 13F (30d) 9 filings 9 filers Visit website Investor relations