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  • MDGL Madrigal Pharmaceuticals, Inc.

MDGL

Madrigal Pharmaceuticals, Inc.

Company with tickers: MDGL

CIK
1157601
CUSIP
558868105
Shares Outstanding
23,055,659
Price History Institutional Holders Short Volume Short Interest Fails to Deliver Financials SEC Filings Earnings Calls Insider Trades Congressional Trades
Holders: 374
Total Value: $11,814,733,879
Total Shares: 22,570,031
Showing 1–100 of 398 holdings by value · page 1 of 4

Institutional Ownership Trend

25 quarters

Holder Concentration

Across 374 13F filers · Δ vs Dec 31, 2025
Top Holder
9.5%
+0.8 pts
Top 5
42.2%
+3.8 pts
Top 10
59.1%
+1.4 pts
HHI
460
Broadly held +30

Quarterly Activity

vs Dec 31, 2025
New
365
Increased
8
Decreased
1
Sold Out
388
Unchanged
0
Holder count: -23
Institutional value: -17.5%
Shares held: -8.2%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds
Large Rockefeller Capital Management L.P. +33,810 33,849
Large BNP PARIBAS ASSET MANAGEMENT Holding S.A. +32,683 32,879
Large Candriam S.C.A. +21,042 84,948
Large Avoro Capital Advisors LLC +10,681 1,818,181
Large PEAK6 LLC +9,325 9,902

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds
Mega GOLDMAN SACHS GROUP INC −28,476 277,371

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD)
Large BAKER BROS. ADVISORS LP 2,141,701 $1,121,116,222
Mega JANUS HENDERSON GROUP PLC 2,018,647 $1,056,701,142
Large RTW INVESTMENTS, LP 1,993,687 $1,043,635,333
Mega BlackRock, Inc. 1,559,965 $816,594,871
Mid PAULSON & CO. INC. 1,392,188 $728,768,652

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD)
Large BAKER BROS. ADVISORS LP 2,141,701 $1,247,198,160
Mid RTW INVESTMENTS, LP 1,993,687 $1,161,003,687
Mid Avoro Capital Advisors LLC 1,807,500 $1,052,579,550
Mid PAULSON & CO. INC. 1,707,522 $994,358,361
Mega BlackRock, Inc. 1,644,750 $957,803,705
100 of 100 shown
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Action
Large BAKER BROS. ADVISORS LP $1,121,116,222 9.49% 2,141,701 View
Mega JANUS HENDERSON GROUP PLC $1,056,701,142 8.94% 2,018,647 View
Large RTW INVESTMENTS, LP $1,043,635,333 8.83% 1,993,687 View
Large Avoro Capital Advisors LLC $951,763,208 8.06% 1,818,181 View
Mega BlackRock, Inc. $816,594,871 6.91% 1,559,965 View
Mid PAULSON & CO. INC. $728,768,652 6.17% 1,392,188 View
Mega WELLINGTON MANAGEMENT GROUP LLP $363,789,662 3.08% 694,958 View
Mega STATE STREET CORP $319,068,051 2.70% 609,525 View
Mega FMR LLC $267,874,254 2.27% 511,728 View
Mega GEODE CAPITAL MANAGEMENT, LLC $238,634,268 2.02% 455,870 View
Mega CITADEL ADVISORS LLC $237,573,195 2.01% 453,843 View
Large WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC $178,251,480 1.51% 340,519 View
Mega Invesco Ltd. $172,493,308 1.46% 329,519 View
Mega PRICE T ROWE ASSOCIATES INC /MD/ $171,755,740 1.45% 328,110 View
Large Polar Capital Holdings Plc $151,445,105 1.28% 289,310 View
Mega GOLDMAN SACHS GROUP INC $145,195,395 1.23% 277,371 View
Mid ARMISTICE CAPITAL, LLC $138,501,263 1.17% 264,583 View
Mid Hood River Capital Management LLC $130,611,523 1.11% 249,511 View
Large LORD, ABBETT & CO. LLC $127,059,779 1.08% 242,726 View
Large Point72 Asset Management, L.P. $118,047,719 1.00% 225,510 View
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $113,446,418 0.96% 216,720 View
Mega BANK OF AMERICA CORP /DE/ $99,211,696 0.84% 189,527 View
Large Pictet Asset Management Holding SA $98,014,522 0.83% 187,240 View
Large ADAGE CAPITAL PARTNERS GP, L.L.C. $97,015,218 0.82% 185,331 View
Large Artisan Partners Limited Partnership $96,077,683 0.81% 183,540 View
Large Fiera Capital Corp $91,089,537 0.77% 174,011 View
Mid Rock Springs Capital Management LP $89,512,846 0.76% 170,999 View
Mega AMERICAN CENTURY COMPANIES INC $85,814,007 0.73% 163,933 View
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $85,482,651 0.72% 163,300 View
Large Erste Asset Management GmbH $83,865,128 0.71% 160,210 View
Mega Bank of New York Mellon Corp $71,143,755 0.60% 135,908 View
Large TORONTO DOMINION BANK $68,291,895 0.58% 130,460 View
Large Woodline Partners LP $65,904,349 0.56% 125,899 View
Mega ALLIANCEBERNSTEIN L.P. $65,667,741 0.56% 125,447 View
Mega JANE STREET GROUP, LLC $65,590,791 0.56% 125,300 View
Mega UBS Group AG $61,653,772 0.52% 117,779 View
Large Caption Management, LLC $61,507,725 0.52% 117,500 View
Mega CITADEL ADVISORS LLC $58,838,028 0.50% 112,400 View
Large Driehaus Capital Management LLC $58,084,231 0.49% 110,960 View
Small Tri Locum Partners LP $54,068,169 0.46% 103,288 View
Mega AMERIPRISE FINANCIAL INC $51,394,804 0.44% 98,181 View
Mega DEUTSCHE BANK AG\ $51,335,130 0.43% 98,067 View
Large WESTFIELD CAPITAL MANAGEMENT CO LP $49,631,761 0.42% 94,813 View
Mid 683 Capital Management, LLC $47,112,300 0.40% 90,000 View
Mid Logos Global Management LP $44,494,950 0.38% 85,000 View
Large Candriam S.C.A. $44,467,729 0.38% 84,948 View
Large ALKEON CAPITAL MANAGEMENT LLC $41,877,599 0.35% 80,000 View
Mega JANE STREET GROUP, LLC $40,883,007 0.35% 78,100 View
Mega D. E. Shaw & Co., Inc. $40,673,619 0.34% 77,700 View
Large NEW YORK STATE COMMON RETIREMENT FUND $39,327,777 0.33% 75,129 View
Mega FRANKLIN RESOURCES INC $38,758,241 0.33% 74,041 View
Large RENAISSANCE TECHNOLOGIES LLC $37,621,788 0.32% 71,870 View
Mega RAYMOND JAMES FINANCIAL INC $34,825,932 0.29% 66,529 View
Mid ArrowMark Colorado Holdings LLC $32,685,990 0.28% 62,441 View
Mega Nuveen, LLC $32,486,547 0.27% 62,060 View
Mega BNP PARIBAS ARBITRAGE, SA $29,930,444 0.25% 57,177 View
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $28,843,197 0.24% 55,100 View
Mid Affinity Asset Advisors, LLC $28,790,850 0.24% 55,000 View
Large Squarepoint Ops LLC $27,683,187 0.23% 52,884 View
Mid EULAV Asset Management $25,650,030 0.22% 49,000 View
Large Russell Investments Group, Ltd. $23,296,504 0.20% 44,504 View
Large Mirae Asset Global Investments Co., Ltd. $21,423,530 0.18% 40,926 View
Mega MILLENNIUM MANAGEMENT LLC $21,385,319 0.18% 40,853 View
Mega SCHRODER INVESTMENT MANAGEMENT GROUP $20,861,326 0.18% 39,852 View
Mid EMERALD ADVISERS, LLC $19,710,739 0.17% 37,654 View
Mega JPMORGAN CHASE & CO $19,009,809 0.16% 36,315 View
Mega CITADEL ADVISORS LLC $19,001,961 0.16% 36,300 View
Mega JANE STREET GROUP, LLC $18,760,117 0.16% 35,838 View
Mid GROUPAMA ASSET MANAGMENT $18,446,035 0.16% 35,238 View
Small PFM Health Sciences, LP $17,874,406 0.15% 34,146 View
Large Rockefeller Capital Management L.P. $17,718,934 0.15% 33,849 View
Large BNP PARIBAS ASSET MANAGEMENT Holding S.A. $17,211,169 0.15% 32,879 View
Mega WELLS FARGO & COMPANY/MN $16,862,014 0.14% 32,212 View
Mid SEGALL BRYANT & HAMILL, LLC $16,682,988 0.14% 31,870 View
Mid Vestal Point Capital, LP $16,472,553 0.14% 31,468 View
Mega D. E. Shaw & Co., Inc. $15,776,861 0.13% 30,139 View
Mega CITIGROUP INC $15,704,100 0.13% 30,000 View
Mid GILDER GAGNON HOWE & CO LLC $15,385,306 0.13% 29,391 View
Mega Swiss National Bank $15,295,793 0.13% 29,220 View
Large Connor, Clark & Lunn Investment Management Ltd. $14,624,181 0.12% 27,937 View
Mega CITIGROUP INC $13,395,073 0.11% 25,589 View
Mid Integral Health Asset Management, LLC $13,086,750 0.11% 25,000 View
Mega Clearbridge Investments, LLC $12,797,271 0.11% 24,447 View
Large SEI INVESTMENTS CO $12,666,926 0.11% 24,198 View
Small Rhenman & Partners Asset Management AB $12,589,453 0.11% 24,050 View
Mega UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $12,456,488 0.11% 23,796 View
Large WCM INVESTMENT MANAGEMENT, LLC $12,332,953 0.10% 23,560 View
Mega California Public Employees Retirement System $12,143,457 0.10% 23,198 View
Large VOYA INVESTMENT MANAGEMENT LLC $11,819,428 0.10% 22,579 View
Large Caption Management, LLC $11,778,075 0.10% 22,500 View
Mega FIRST TRUST ADVISORS LP $11,638,308 0.10% 22,233 View
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $11,629,409 0.10% 22,216 View
Large MARSHALL WACE, LLP $11,465,039 0.10% 21,902 View
Mega RHUMBLINE ADVISERS $11,392,801 0.10% 21,764 View
Mega MORGAN STANLEY $11,012,759 0.09% 21,038 View
Small Tao Capital Management LP $10,992,870 0.09% 21,000 View
Mega D. E. Shaw & Co., Inc. $10,207,665 0.09% 19,500 View
Large Universal- Beteiligungs- und Servicegesellschaft mbH $9,659,068 0.08% 18,452 View
Large CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $8,923,593 0.08% 17,047 View
Large FEDERATED HERMES, INC. $8,848,212 0.07% 16,903 View
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