TWO SIGMA INVESTMENTS, LP

Position in DHR — Danaher Corp /De/

CIK 1179392 NEW YORK, NY

Back to DHR Full portfolio

Position in DHR

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$86,240,200

-$266,184,867 QoQ

Shares Held

452,752

-75.6% QoQ

Ownership

0.064%

of shares outstanding

% of Portfolio

0.07%

of 13F equity value

Holder Rank

#150

of 2,098 holders

Holding Since

Mar 2020

22 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Common Shares in DHR Over Time

Shares Held

Position Value (USD)

Derivatives in DHR

reported options exposure · as of Dec 31, 2025

CallValue

$2,060,280

CallShares

9,000

PutValue

$1,236,168

PutShares

5,400

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Diagnostics & Research

Healthcare · as of Jun 30, 2026

TWO SIGMA INVESTMENTS, LP holds $744,220,642 across 29 Diagnostics & Research names. DHR ranks #2 (11.6% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	GH	Guardant Health, Inc.	3,719,301	$558,006,729
2	DHR	Danaher Corp /De/ This page	452,752	$86,240,200
3	CDNA	CareDx, Inc.	401,987	$11,456,629
4	TWST	Twist Bioscience Corp	94,600	$9,732,448
5	IQV	Iqvia Holdings Inc.	48,191	$9,311,465
6	MYGN	Myriad Genetics Inc	1,557,727	$8,894,621
7	NTRA	Natera, Inc.	32,600	$8,849,270
8	TMO	Thermo Fisher Scientific Inc.	17,014	$8,530,139

All Filings in DHR

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37 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$86,240,200	452,752	-75.6%	Shares	Sole	2026-08-14
2026-03-31	$352,425,067	1,858,782	+6282.5%	Shares	Sole	2026-05-15
2025-12-31	$6,666,837	29,123	-97.2%	Shares	Sole	2026-02-17
2025-12-31	$1,236,168	5,400	-88.1%	Put	Sole	2026-02-17
2025-12-31	$2,060,280	9,000	-60.0%	Call	Sole	2026-02-17
2025-09-30	$209,219,218	1,055,277	-11.3%	Shares	Sole	2025-11-14
2025-06-30	$235,009,189	1,189,679	+7.6%	Shares	Sole	2025-08-14
2025-03-31	$226,648,205	1,105,601	+7.6%	Shares	Sole	2025-05-15
2024-12-31	$235,861,477	1,027,495	+316.7%	Shares	Sole	2025-02-14
2024-09-30	$68,549,723	246,564	+273.0%	Shares	Sole	2024-11-14
2024-03-31	$16,506,741	66,101	-82.0%	Shares	Sole	2024-05-15
2023-06-30	$88,318,337	367,993	-64.2%	Shares	Sole	2023-08-14
2023-03-31	$258,895,217	1,027,199	+406.2%	Shares	Sole	2023-05-15
2023-03-31	$11,392,207	45,200	-14.7%	Put	Sole	2023-05-15
2022-12-31	$53,856,102	202,909	+62.4%	Shares	Sole	2023-02-14
2022-12-31	$14,067,258	53,000	0.0%	Put	Sole	2023-02-14
2022-09-30	$13,689,370	53,000	0.0%	Put	Sole	2022-11-14
2022-09-30	$32,262,229	124,907	+44.3%	Shares	Sole	2022-11-14
2022-06-30	$21,947,989	86,573	-67.7%	Shares	Sole	2022-08-15
2022-06-30	$13,436,561	53,000	+579.5%	Put	Sole	2022-08-15
2022-03-31	$2,287,973	7,800	-70.7%	Put	Sole	2022-05-16
2021-12-31	$7,402,724	22,500	+181.2%	Call	Sole	2022-02-14
2021-12-31	$88,091,759	267,748	-56.1%	Shares	Sole	2022-02-14
2021-12-31	$8,751,665	26,600	+280.0%	Put	Sole	2022-02-14
2021-09-30	$185,701,690	609,978	+401.6%	Shares	Sole	2021-11-15
2021-09-30	$2,435,519	8,000	-28.6%	Call	Sole	2021-11-15
2021-09-30	$2,131,079	7,000	-54.2%	Put	Sole	2021-11-15
2021-03-31	$2,520,895	11,200	+1020.0%	Call	Sole	2021-05-17
2021-03-31	$3,443,723	15,300	+188.7%	Put	Sole	2021-05-17
2021-03-31	$27,372,202	121,611	-49.3%	Shares	Sole	2021-05-17
2020-12-31	$222,139	1,000	-50.0%	Call	Sole	2021-02-16
2020-12-31	$53,235,622	239,649	-72.4%	Shares	Sole	2021-02-16
2020-12-31	$1,177,341	5,300	+211.8%	Put	Sole	2021-02-16
2020-09-30	$186,850,894	867,742	+3149.4%	Shares	Sole	2020-11-16
2020-06-30	$4,722,245	26,705	—	Shares	Sole	2020-08-14
2020-03-31	$276,819	2,000	—	Call	Sole	2020-05-15
2020-03-31	$235,296	1,700	—	Put	Sole	2020-05-15
No filing history on record for this holder in this stock.