Position in GH
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$558,006,729
+$167,324,951 QoQ
Shares Held
3,719,301
-12.1% QoQ
Ownership
2.77%
of shares outstanding
% of Portfolio
0.46%
of 13F equity value
Holder Rank
#8
of 594 holders
Holding Since
Mar 2020
23 quarters on record
Voting authority
Sole 98%
Shared 0%
None 2%
Common Shares in GH Over Time
Shares Held
Position Value (USD)
Derivatives in GH
reported options exposure · as of Jun 30, 2026CallValue
$1,335,267
CallShares
8,900
PutValue
$2,175,435
PutShares
14,500
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Diagnostics & Research
Healthcare · as of Jun 30, 2026TWO SIGMA INVESTMENTS, LP holds $744,220,642 across 29 Diagnostics & Research names. GH ranks #1 (75.0% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | GH |
Guardant Health, Inc.
This page
|
3,719,301 | $558,006,729 | |
| 2 | DHR |
Danaher Corp /De/
|
452,752 | $86,240,200 | |
| 3 | CDNA |
CareDx, Inc.
|
401,987 | $11,456,629 | |
| 4 | TWST |
Twist Bioscience Corp
|
94,600 | $9,732,448 | |
| 5 | IQV |
Iqvia Holdings Inc.
|
48,191 | $9,311,465 | |
| 6 | MYGN |
Myriad Genetics Inc
|
1,557,727 | $8,894,621 | |
| 7 | NTRA |
Natera, Inc.
|
32,600 | $8,849,270 | |
| 8 | TMO |
Thermo Fisher Scientific Inc.
|
17,014 | $8,530,139 |
All Filings in GH
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32 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $558,006,729 | 3,719,301 | Shares | Sole | 2026-08-14 | |
| 2026-06-30 | $1,335,267 | 8,900 | Call | Sole | 2026-08-14 | |
| 2026-06-30 | $2,175,435 | 14,500 | Put | Sole | 2026-08-14 | |
| 2026-03-31 | $390,681,778 | 4,229,531 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $204,280 | 2,000 | Put | Sole | 2026-02-17 | |
| 2025-12-31 | $204,280 | 2,000 | Call | Sole | 2026-02-17 | |
| 2025-12-31 | $221,838,172 | 2,171,903 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $112,672,120 | 1,803,331 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $96,513,956 | 1,854,611 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $77,781,763 | 1,825,863 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $57,761,312 | 1,890,714 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $31,321,037 | 1,365,346 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $23,523,424 | 814,523 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $5,176,644 | 250,928 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $15,812,266 | 584,557 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $32,659,515 | 1,101,873 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $36,446,118 | 1,018,048 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $18,434,552 | 786,457 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $13,257,824 | 487,420 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $9,667,814 | 179,599 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $9,351,457 | 231,816 | Shares | Sole | 2022-08-15 | |
| 2021-12-31 | $800,160 | 8,000 | Put | Sole | 2022-02-14 | |
| 2021-09-30 | $275,022 | 2,200 | Put | Sole | 2021-11-15 | |
| 2021-09-30 | $887,571 | 7,100 | Call | Sole | 2021-11-15 | |
| 2021-09-30 | $275,022 | 2,200 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $17,694,715 | 142,481 | Shares | Sole | 2021-08-16 | |
| 2021-06-30 | $372,570 | 3,000 | Call | Sole | 2021-08-16 | |
| 2021-06-30 | $484,341 | 3,900 | Put | Sole | 2021-08-16 | |
| 2021-03-31 | $18,463,933 | 120,956 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $355,193 | 2,756 | Shares | Sole | 2021-02-16 | |
| 2020-03-31 | $1,545,120 | 22,200 | Put | Sole | 2020-05-15 | |
| 2020-03-31 | $682,080 | 9,800 | Call | Sole | 2020-05-15 | |
| No filing history on record for this holder in this stock. | ||||||