HROW · Harrow, Inc. · Insider Trading

The sale reported in this Form 4 was effected as part of a broker-assisted same-day sale transaction in connection with the option exercise reported herein to fund the aggregate exercise price and related transaction costs. The Reporting Person did not retain any shares acquired upon exercise.

The option was granted on January 6, 2025. The shares subject to the option vest according to the following schedule: 25% of the shares vested at the one-year anniversary of the date of grant, and the remaining shares vest over the next three years in 12 equal quarterly installments until fully vested and exercisable on January 6, 2029.

The sale reported in this Form 4 was effected as part of a broker-assisted same-day sale transaction in connection with the option exercise reported herein to fund the aggregate exercise price and related transaction costs. The Reporting Person did not retain any shares acquired upon exercise.

The Restricted Stock Units were received as a compensatory award for services rendered or to be rendered.

The Restricted Stock Units vest in equal quarterly installments over a one-year period following the date of grant, subject to the Reporting Person's continued service. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the termination of service.

The Restricted Stock Units were received as a compensatory award for services rendered or to be rendered.

The Restricted Stock Units vest in equal quarterly installments over a one-year period following the date of grant, subject to the Reporting Person's continued service. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the termination of service.

The Restricted Stock Units were received as a compensatory award for services rendered or to be rendered.

The Restricted Stock Units vest in equal quarterly installments over a one-year period following the date of grant, subject to the Reporting Person's continued service. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the termination of service.

Each restricted stock unit represents a contingent right to receive one share of Harrow, Inc. common stock.

The restricted stock units vest in full on May 15, 2029, subject to the Reporting Person's continued service through such date.

The price reported in Column 4 is a weighted average purchase price. The shares were purchased in multiple transactions at prices ranging from $30.18 to $30.34, inclusive. The reporting person undertakes to provide to Harrow, Inc., any security holder of Harrow, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

Represents an aggregate of two open market purchases effected on May 14, 2026, each at a price of $29.90 per share. The reporting person undertakes to provide to Harrow, Inc., any security holder of Harrow, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each transaction as set forth in this footnote.

The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.12 to $40.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range.

Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.12 to $40.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range.

Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $38.50 to $40.66. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range.

Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $38.50 to $40.66. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range.

Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

Represents restricted stock units ("RSU's) granted under the Issuers 2025 Incentive and Awards Plan, (the "Plan"). Each RSU represents a right to receive one share of common stock of the Issuer upon vesting. The RSU's have a five-year term and vest when Harrow's revenue reaches $230,000,000 in a calendar quarterly period.

Represents RSUs granted under the Plan. Each RSU represents a right to receive one share of common stock of the Issuer upon vesting. The RSU's will vest in full after 3 years from the date of the award on 1/30/2029.

Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $53.00 - $53.93 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each price.

Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

Represents stock options granted to Mr. Baum on April 1, 2016 under the Issuer's 2007 Stock Incentive and Awards Plan, as amended. The stock options vested quarterly over a three-year period following the grant date. 79,994 shares were withheld to satisfy the exercise price and tax liability incident to the exercise of the stock option. Such withholding did not involve any market sales or other market transactions.

Represents stock options granted to Mr. Boll on April 1, 2016 under the Issuer's 2007 Stock Incentive and Awards Plan, as amended. The stock options vested quarterly over a three-year period following the grant date. 26,665 shares were withheld to satisfy the exercise price and tax liability incident to the exercise of the stock option. Such withholding did not involve any market sales or other market transactions.

The shares subject to the option shall vest according to the following schedule: 25% of the shares shall vest at the one-year anniversary of the date of grant, and the remaining shares shall vest over the next three years in 12 equal quarterly installments until fully vested and exercisable on September 1, 2029.

Represents performance-based restricted stock units ("PSUs") granted under the Issuer's 2025 Stock Incentive and Awards Plan, (the "Plan"). Each PSU represents a contingent right to receive one share of common stock of the Issuer upon vesting. The vesting of the PSUs (granted in lieu of service only stock option and restricted stock unit awards) require (i) a minimum of a three-year service period, and (ii) the achievement and maintenance of Harrow common stock price targets of $50 (causing the vesting of 124,530 PSU shares), $60 (causing the vesting of 186,795 PSU shares), $75 (causing the vesting of 257,955 PSU shares), $100 (causing the vesting of 320,220 PSU shares).

Represents performance-based restricted stock units ("PSUs") granted under the Issuer's 2025 Stock Incentive and Awards Plan, (the "Plan"). Each PSU represents a contingent right to receive one share of common stock of the Issuer upon vesting. The vesting of the PSUs (granted in lieu of service only stock option and restricted stock unit awards) require (i) a minimum of a three-year service period, and (ii) the achievement and maintenance of Harrow common stock price targets of $50 (causing the vesting of 56,805 PSU shares), $60 (causing the vesting of 85,208 PSU shares), $75 (causing the vesting of 117,668 PSU shares), $100 (causing the vesting of 146,069 PSU shares).

The Restricted Stock Units were received as a compensatory award for services rendered or to be rendered.

Award of Restricted Stock Units vests in full on the one-year anniversary following the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the termination of service.

The Restricted Stock Units were received as a compensatory award for services rendered or to be rendered.

Award of Restricted Stock Units vests in full on the one-year anniversary following the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the termination of service.

The Restricted Stock Units were received as a compensatory award for services rendered or to be rendered.

Award of Restricted Stock Units vests in full on the one-year anniversary following the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the termination of service.

The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $30.515 - $31.235 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.

Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $30.09 - $31.32 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.

Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $30.01 - $30.07 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.

The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $30.00 - $30.115 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.

Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $30.01 - $30.07 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.

Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $30.00 - $30.115 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.

Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $26.5214 - $26.6565 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.

Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $25.1642 - $26.4028 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.

Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $25.1642 - $26.4028 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.

Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $26.5214 - $26.6565 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.

Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

The 277,200 shares of Harrow, Inc. ("Harrow") common stock listed in Table I as "Acquired" represent shares upon vesting of performance stock units ("PSUs") granted to Mr. Saharek under Harrow's 2017 Stock Incentive and Awards Plan (the "Incentive Plan") on April 3, 2023. The PSUs vested on April 3, 2025 and were settled in full in shares of Harrow common stock (on a one-for-one basis) on April 7, 2025, following attainment of (i) a two-year service period, and (ii) the achievement of Harrow common stock price targets ranging from $25 - $50. The 109,475 shares of Harrow common stock listed in Table I as "Disposed" were not sold by Mr. Saharek in any market transaction; rather, they were shares of Harrow common stock withheld by the Company for payroll tax purposes from the same aforementioned 277,200 shares pursuant to the terms of the Incentive Plan.

The 762,300 shares of Harrow, Inc. ("Harrow") common stock listed in Table I as "Acquired" represent shares upon vesting of performance stock units ("PSUs") granted to Mr. Baum under Harrow's 2017 Stock Incentive and Awards Plan (the "Incentive Plan") on April 3, 2023. The PSUs vested on April 3, 2025 and were settled in full in shares of Harrow common stock (on a one-for-one basis) on April 7, 2025, following attainment of (i) a two-year service period, and (ii) the achievement of Harrow common stock price targets ranging from $25 - $50. The 300,363 shares of Harrow common stock listed in Table I as "Disposed" were not sold by Mr. Baum in any market transaction; rather, they were shares of Harrow common stock withheld by the Company for payroll tax purposes from the same aforementioned 762,300 shares pursuant to the terms of the Incentive Plan.

The 346,500 shares of Harrow, Inc. ("Harrow") common stock listed in Table I as "Acquired" represent shares upon vesting of performance stock units ("PSUs") granted to Mr. Boll under Harrow's 2017 Stock Incentive and Awards Plan (the "Incentive Plan") on April 3, 2023. The PSUs vested on April 3, 2025 and were settled in full in shares of Harrow common stock (on a one-for-one basis) on April 7, 2025, following attainment of (i) a two-year service period, and (ii) the achievement of Harrow common stock price targets ranging from $25 - $50. The 136,745 shares of Harrow common stock listed in Table I as "Disposed" were not sold by Mr. Boll in any market transaction; rather, they were shares of Harrow common stock withheld by the Company for payroll tax purposes from the same aforementioned 346,500 shares pursuant to the terms of the Incentive Plan.

The 277,200 shares of Harrow, Inc. ("Harrow") common stock listed in Table I as "Acquired" represent shares upon vesting of performance stock units ("PSUs") granted to Mr. Saharek under Harrow's 2017 Stock Incentive and Awards Plan (the "Incentive Plan") on April 3, 2023. The PSUs vested on April 3, 2025 and were settled in full in shares of Harrow common stock (on a one-for-one basis) on April 7, 2025, following attainment of (i) a two-year service period, and (ii) the achievement of Harrow common stock price targets ranging from $25 - $50. The 109,475 shares of Harrow common stock listed in Table I as "Disposed" were not sold by Mr. Saharek in any market transaction; rather, they were shares of Harrow common stock withheld by the Company for payroll tax purposes from the same aforementioned 277,200 shares pursuant to the terms of the Incentive Plan.

The 762,300 shares of Harrow, Inc. ("Harrow") common stock listed in Table I as "Acquired" represent shares upon vesting of performance stock units ("PSUs") granted to Mr. Baum under Harrow's 2017 Stock Incentive and Awards Plan (the "Incentive Plan") on April 3, 2023. The PSUs vested on April 3, 2025 and were settled in full in shares of Harrow common stock (on a one-for-one basis) on April 7, 2025, following attainment of (i) a two-year service period, and (ii) the achievement of Harrow common stock price targets ranging from $25 - $50. The 300,363 shares of Harrow common stock listed in Table I as "Disposed" were not sold by Mr. Baum in any market transaction; rather, they were shares of Harrow common stock withheld by the Company for payroll tax purposes from the same aforementioned 762,300 shares pursuant to the terms of the Incentive Plan.

The 346,500 shares of Harrow, Inc. ("Harrow") common stock listed in Table I as "Acquired" represent shares upon vesting of performance stock units ("PSUs") granted to Mr. Boll under Harrow's 2017 Stock Incentive and Awards Plan (the "Incentive Plan") on April 3, 2023. The PSUs vested on April 3, 2025 and were settled in full in shares of Harrow common stock (on a one-for-one basis) on April 7, 2025, following attainment of (i) a two-year service period, and (ii) the achievement of Harrow common stock price targets ranging from $25 - $50. The 136,745 shares of Harrow common stock listed in Table I as "Disposed" were not sold by Mr. Boll in any market transaction; rather, they were shares of Harrow common stock withheld by the Company for payroll tax purposes from the same aforementioned 346,500 shares pursuant to the terms of the Incentive Plan.

The 346,500 shares of Harrow, Inc. ("Harrow") common stock listed in Table I as "Acquired" represent shares upon vesting of performance stock units ("PSUs") granted to Mr. Boll under Harrow's 2017 Stock Incentive and Awards Plan (the "Incentive Plan") on April 3, 2023. The PSUs vested on April 3, 2025 and were settled in full in shares of Harrow common stock (on a one-for-one basis) on April 7, 2025, following attainment of (i) a two-year service period, and (ii) the achievement of Harrow common stock price targets ranging from $25 - $50. The 136,745 shares of Harrow common stock listed in Table I as "Disposed" were not sold by Mr. Boll in any market transaction; rather, they were shares of Harrow common stock withheld by the Company for payroll tax purposes from the same aforementioned 346,500 shares pursuant to the terms of the Incentive Plan.

The 762,300 shares of Harrow, Inc. ("Harrow") common stock listed in Table I as "Acquired" represent shares upon vesting of performance stock units ("PSUs") granted to Mr. Baum under Harrow's 2017 Stock Incentive and Awards Plan (the "Incentive Plan") on April 3, 2023. The PSUs vested on April 3, 2025 and were settled in full in shares of Harrow common stock (on a one-for-one basis) on April 7, 2025, following attainment of (i) a two-year service period, and (ii) the achievement of Harrow common stock price targets ranging from $25 - $50. The 300,363 shares of Harrow common stock listed in Table I as "Disposed" were not sold by Mr. Baum in any market transaction; rather, they were shares of Harrow common stock withheld by the Company for payroll tax purposes from the same aforementioned 762,300 shares pursuant to the terms of the Incentive Plan.

The 277,200 shares of Harrow, Inc. ("Harrow") common stock listed in Table I as "Acquired" represent shares upon vesting of performance stock units ("PSUs") granted to Mr. Saharek under Harrow's 2017 Stock Incentive and Awards Plan (the "Incentive Plan") on April 3, 2023. The PSUs vested on April 3, 2025 and were settled in full in shares of Harrow common stock (on a one-for-one basis) on April 7, 2025, following attainment of (i) a two-year service period, and (ii) the achievement of Harrow common stock price targets ranging from $25 - $50. The 109,475 shares of Harrow common stock listed in Table I as "Disposed" were not sold by Mr. Saharek in any market transaction; rather, they were shares of Harrow common stock withheld by the Company for payroll tax purposes from the same aforementioned 277,200 shares pursuant to the terms of the Incentive Plan.

Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.