Stocks
IONS
D. E. Shaw & Co., Inc.

D. E. Shaw & Co., Inc.

CIK

0001009207

City

New York

State / Country

Stock

IONS — IONIS PHARMACEUTICALS INC

Holdings in IONS

Position Over Time

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2025-12-31	$26,328,045	332,803	-47.3%	Shares	Defined	2026-02-17
2025-09-30	$41,275,963	630,938	+2628.6%	Shares	Defined	2025-11-14
2024-12-31	$808,379	23,123	-84.1%	Shares	Defined	2025-02-14
2024-09-30	$5,812,344	145,091	-23.9%	Shares	Defined	2024-11-14
2024-06-30	$9,092,622	190,781	-47.3%	Shares	Defined	2024-08-14
2023-09-30	$16,422,361	362,045	+84.5%	Shares	Defined	2023-11-14
2023-06-30	$8,050,619	196,213	+126.4%	Shares	Defined	2023-08-14
2023-03-31	$3,096,906	86,651	-71.0%	Shares	Defined	2023-05-15
2022-12-31	$11,301,954	299,231	+42.9%	Shares	Defined	2023-02-14
2022-09-30	$9,263,751	209,445	+65.4%	Shares	Defined	2022-11-14
2022-06-30	$4,687,509	126,621	-21.2%	Shares	Defined	2022-08-15
2021-12-31	$4,888,853	160,659	+27.4%	Shares	Defined	2022-02-14
2021-09-30	$4,229,595	126,106	+1316.9%	Shares	Defined	2021-11-15
2021-06-30	$355,021	8,900	-88.1%	Shares	Defined	2021-08-16
2021-06-30	$2,978,426	74,666	+821.1%	Shares	Defined	2021-08-16
2021-03-31	$364,445	8,106	-8.9%	Shares	Defined	2021-05-17
2021-03-31	$400,144	8,900	0.0%	Shares	Defined	2021-05-17
2020-12-31	$503,206	8,900	-33.7%	Shares	Defined	2021-02-16
2020-12-31	$758,597	13,417	-65.5%	Shares	Defined	2021-02-16
2020-12-31	$2,199,406	38,900	+337.1%	Shares	Defined	2021-02-16
2020-09-30	$422,305	8,900	-96.0%	Shares	Defined	2020-11-16
2020-09-30	$10,588,420	223,149	+473.6%	Shares	Defined	2020-11-16
2020-09-30	$1,845,805	38,900	+337.1%	Shares	Defined	2020-11-16
2020-06-30	$524,744	8,900	-92.1%	Shares	Defined	2020-08-14
2020-06-30	$6,654,933	112,872	+190.2%	Shares	Defined	2020-08-14
2020-06-30	$2,293,544	38,900	+55.6%	Shares	Defined	2020-08-14
2020-03-31	$1,181,810	24,996	-35.7%	Shares	Defined	2020-05-15
2020-03-31	$1,839,192	38,900	—	Shares	Defined	2020-05-15