Position in IONS
as of Dec 31, 2025
· filed Jan 29, 2026
Position Value
$1,300,604,709
+$222,369,934 QoQ
Shares Held
16,440,459
-0.3% QoQ
Ownership
9.95%
of shares outstanding
% of Portfolio
0.02%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2020
24 quarters on record
Voting authority
Sole 0.ToString("F0")%
Shared 6.3951864117662405.ToString("F0")%
None 93.60481358823375.ToString("F0")%
Common Shares in IONS Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Dec 31, 2025VANGUARD GROUP INC holds $65,710,756,184 across 450 Biotechnology names. IONS ranks #7 (2.0% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
24,105,823 | $10,928,615,912 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
9,075,153 | $7,004,838,343 | |
| 3 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
13,553,932 | $5,389,721,058 | |
| 4 | INSM |
INSMED Inc
|
21,076,344 | $3,668,126,907 | |
| 5 | INCY |
Incyte Corp
|
19,911,434 | $1,966,652,333 | |
| 6 | RVMD |
Revolution Medicines, Inc.
|
16,719,886 | $1,331,738,919 | |
| 7 | IONS |
Ionis Pharmaceuticals Inc
This page
|
16,440,459 | $1,300,604,709 | |
| 8 | BBIO |
BridgeBio Pharma, Inc.
|
16,862,691 | $1,289,827,232 |
All Filings in IONS
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24 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2025-12-31 | $1,300,604,709 | 16,440,459 | Shares | Sole | 2026-01-29 | |
| 2025-09-30 | $1,078,234,775 | 16,481,730 | Shares | Defined | 2025-11-07 | |
| 2025-06-30 | $660,403,564 | 16,714,846 | Shares | Defined | 2025-08-11 | |
| 2025-03-31 | $494,303,287 | 16,383,934 | Shares | Defined | 2025-05-09 | |
| 2024-12-31 | $575,879,962 | 16,472,539 | Shares | Defined | 2025-02-11 | |
| 2024-09-30 | $603,133,663 | 15,055,758 | Shares | Defined | 2024-11-13 | |
| 2024-06-30 | $659,886,633 | 13,845,712 | Shares | Defined | 2024-08-13 | |
| 2024-03-31 | $582,210,266 | 13,430,456 | Shares | Defined | 2024-05-10 | |
| 2023-12-31 | $718,554,101 | 14,203,481 | Shares | Defined | 2024-03-11 | |
| 2023-09-30 | $657,811,852 | 14,502,025 | Shares | Sole | 2023-12-18 | |
| 2023-06-30 | $595,889,602 | 14,523,266 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $499,494,733 | 13,975,790 | Shares | Sole | 2023-07-14 | |
| 2022-12-31 | $511,658,630 | 13,546,694 | Shares | Defined | 2023-02-10 | |
| 2022-09-30 | $566,410,395 | 12,806,023 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $451,654,216 | 12,200,276 | Shares | Sole | 2022-08-12 | |
| 2022-03-31 | $448,148,218 | 12,099,034 | Shares | Sole | 2022-05-13 | |
| 2021-12-31 | $365,375,320 | 12,007,076 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $395,772,300 | 11,800,009 | Shares | Sole | 2021-11-12 | |
| 2021-06-30 | $504,841,018 | 12,655,829 | Shares | Defined | 2021-08-13 | |
| 2021-03-31 | $566,682,536 | 12,604,149 | Shares | Defined | 2021-05-14 | |
| 2020-12-31 | $692,297,695 | 12,244,388 | Shares | Defined | 2021-02-12 | |
| 2020-09-30 | $568,926,922 | 11,990,030 | Shares | Sole | 2020-11-16 | |
| 2020-06-30 | $725,576,555 | 12,306,251 | Shares | Defined | 2020-08-14 | |
| 2020-03-31 | $569,892,361 | 12,053,561 | Shares | Sole | 2020-05-15 | |
| No filing history on record for this holder in this stock. | ||||||