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Equibles

JANE STREET GROUP, LLC

Position in IONS — Ionis Pharmaceuticals Inc

CIK 1595888 NEW YORK, NY
Back to IONS Full portfolio

Position in IONS

as of Mar 31, 2026 · filed May 12, 2026
Position Value
$14,403,611
+$11,993,051 QoQ
Shares Held
191,818
+529.5% QoQ
Ownership
0.116%
of shares outstanding
% of Portfolio
0.02%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2020
25 quarters on record
Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Common Shares in IONS Over Time

Shares Held

Position Value (USD)

Derivatives in IONS

reported options exposure · as of Mar 31, 2026
CallValue
$21,678,483
CallShares
288,700
PutValue
$21,010,182
PutShares
279,800

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Mar 31, 2026

JANE STREET GROUP, LLC holds $1,255,284,514 across 317 Biotechnology names. IONS ranks #22 (1.1% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 BBIO
BridgeBio Pharma, Inc.
 1,757,672 $130,524,721
2 RPRX
Royalty Pharma plc
 2,400,382 $115,146,324
3 TGTX
Tg Therapeutics, Inc.
 2,041,669 $67,824,242
4 VRTX
Vertex Pharmaceuticals Inc / Ma
 122,946 $54,900,305
5 HALO
Halozyme Therapeutics, Inc.
 831,707 $53,753,223
6 EXEL
Exelixis, Inc.
 1,087,030 $46,622,715
7 JAZZ
Jazz Pharmaceuticals plc
 223,615 $42,274,415
8 BNTX
BioNTech SE
 336,757 $29,930,962

All Filings in IONS

Export CSV
50 filing rows on record
Report Date Value (USD) Shares
2026-03-31 $14,403,611 191,818
2026-03-31 $21,010,182 279,800
2026-03-31 $21,678,483 288,700
2025-12-31 $2,410,560 30,471
2025-12-31 $5,506,056 69,600
2025-12-31 $1,257,849 15,900
2025-09-30 $4,481,270 68,500
2025-09-30 $1,779,424 27,200
2025-09-30 $23,882,878 365,070
2025-06-30 $912,681 23,100
2025-06-30 $2,299,482 58,200
2025-03-31 $1,801,149 59,700
2025-03-31 $1,632,709 54,117
2025-03-31 $485,737 16,100
2024-12-31 $5,755,602 164,634
2024-12-31 $2,108,088 60,300
2024-12-31 $1,027,824 29,400
2024-09-30 $1,189,782 29,700
2024-09-30 $7,072,993 176,560
2024-09-30 $236,354 5,900
2024-06-30 $8,542,863 179,246
2024-03-31 $5,121,021 118,132
2023-12-31 $7,799,155 154,164
2023-09-30 $11,498,350 253,491
2023-06-30 $4,444,532 108,324
2023-03-31 $3,713,420 103,901
2022-12-31 $433,599 11,480
2022-09-30 $912,420 20,629
2022-06-30 $3,364,709 90,889
2022-03-31 $1,111,200 30,000
2022-03-31 $1,722,360 46,500
2022-03-31 $1,029,378 27,791
2021-12-31 $1,996,208 65,600
2021-12-31 $1,241,544 40,800
2021-12-31 $1,599,096 52,550
2021-09-30 $2,162,524 64,476
2021-09-30 $1,130,298 33,700
2021-09-30 $1,079,988 32,200
2021-06-30 $1,707,292 42,800
2021-06-30 $1,851,574 46,417
2021-06-30 $1,033,151 25,900
2021-03-31 $2,445,824 54,400
2021-03-31 $1,618,560 36,000
2021-03-31 $1,477,520 32,863
2020-12-31 $2,815,692 49,800
2020-12-31 $2,538,646 44,900
2020-12-31 $4,559,496 80,642
2020-09-30 $1,575,340 33,200
2020-09-30 $3,754,054 79,116
2020-09-30 $2,130,505 44,900

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