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Equibles

JANE STREET GROUP, LLC

Position in IONS — Ionis Pharmaceuticals Inc

CIK 1595888 NEW YORK, NY
Back to IONS Full portfolio

Position in IONS

as of Jun 30, 2026 · filed Aug 14, 2026
Position Value
$39,934,169
+$25,530,558 QoQ
Shares Held
503,647
+162.6% QoQ
Ownership
0.303%
of shares outstanding
% of Portfolio
0.03%
of 13F equity value
Holder Rank
#56
of 513 holders
Holding Since
Mar 2020
26 quarters on record
Voting authority Sole 100% Shared 0% None 0%

Common Shares in IONS Over Time

Shares Held

Position Value (USD)

Derivatives in IONS

reported options exposure · as of Jun 30, 2026
CallValue
$44,045,595
CallShares
555,500
PutValue
$43,070,328
PutShares
543,200

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Jun 30, 2026

JANE STREET GROUP, LLC holds $1,372,940,661 across 293 Biotechnology names. IONS ranks #10 (2.9% of the industry book) .

# Ticker Company Shares Value (USD) Open
1 BBIO
BridgeBio Pharma, Inc.
 2,934,193 $218,538,693
2 MDGL
Madrigal Pharmaceuticals, Inc.
 191,541 $102,847,939
3 AXSM
Axsome Therapeutics, Inc.
 403,995 $98,885,855
4 TGTX
Tg Therapeutics, Inc.
 1,752,646 $96,290,370
5 EXEL
Exelixis, Inc.
 1,402,438 $76,306,651
6 QURE
uniQure N.V.
 1,610,483 $74,178,846
7 HALO
Halozyme Therapeutics, Inc.
 694,684 $54,372,915
8 TVTX
Travere Therapeutics, Inc.
 938,699 $53,327,489

All Filings in IONS

Export CSV
50 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $44,045,595 555,500
2026-06-30 $39,934,169 503,647
2026-06-30 $43,070,328 543,200
2026-03-31 $14,403,611 191,818
2026-03-31 $21,010,182 279,800
2026-03-31 $21,678,483 288,700
2025-12-31 $2,410,560 30,471
2025-12-31 $5,506,056 69,600
2025-12-31 $1,257,849 15,900
2025-09-30 $4,481,270 68,500
2025-09-30 $1,779,424 27,200
2025-09-30 $23,882,878 365,070
2025-06-30 $912,681 23,100
2025-06-30 $2,299,482 58,200
2025-03-31 $485,737 16,100
2025-03-31 $1,632,709 54,117
2025-03-31 $1,801,149 59,700
2024-12-31 $5,755,602 164,634
2024-12-31 $2,108,088 60,300
2024-12-31 $1,027,824 29,400
2024-09-30 $1,189,782 29,700
2024-09-30 $7,072,993 176,560
2024-09-30 $236,354 5,900
2024-06-30 $8,542,863 179,246
2024-03-31 $5,121,021 118,132
2023-12-31 $7,799,155 154,164
2023-09-30 $11,498,350 253,491
2023-06-30 $4,444,532 108,324
2023-03-31 $3,713,420 103,901
2022-12-31 $433,599 11,480
2022-09-30 $912,420 20,629
2022-06-30 $3,364,709 90,889
2022-03-31 $1,111,200 30,000
2022-03-31 $1,722,360 46,500
2022-03-31 $1,029,378 27,791
2021-12-31 $1,996,208 65,600
2021-12-31 $1,241,544 40,800
2021-12-31 $1,599,096 52,550
2021-09-30 $2,162,524 64,476
2021-09-30 $1,130,298 33,700
2021-09-30 $1,079,988 32,200
2021-06-30 $1,707,292 42,800
2021-06-30 $1,851,574 46,417
2021-06-30 $1,033,151 25,900
2021-03-31 $2,445,824 54,400
2021-03-31 $1,618,560 36,000
2021-03-31 $1,477,520 32,863
2020-12-31 $2,815,692 49,800
2020-12-31 $2,538,646 44,900
2020-12-31 $4,559,496 80,642