CHARLES SCHWAB INVESTMENT MANAGEMENT INC
Position in IONS — Ionis Pharmaceuticals Inc
CIK 884546
SAN FRANCISCO, CA
Position in IONS
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$118,887,443
-$3,087,598 QoQ
Shares Held
1,583,266
+2.7% QoQ
Ownership
0.958%
of shares outstanding
% of Portfolio
0.02%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2020
25 quarters on record
Voting authority
Sole 99.99690513154455.ToString("F0")%
Shared 0.ToString("F0")%
None 0.003094868455458527.ToString("F0")%
Common Shares in IONS Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Mar 31, 2026CHARLES SCHWAB INVESTMENT MANAGEMENT INC holds $6,182,986,350 across 288 Biotechnology names. IONS ranks #10 (1.9% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
1,920,871 | $857,745,736 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
804,508 | $621,595,061 | |
| 3 | MRNA |
Moderna, Inc.
|
4,734,356 | $240,505,284 | |
| 4 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
673,356 | $222,793,299 | |
| 5 | INSM |
INSMED Inc
|
1,069,390 | $174,866,652 | |
| 6 | RVMD |
Revolution Medicines, Inc.
|
1,735,476 | $168,775,041 | |
| 7 | INCY |
Incyte Corp
|
1,729,102 | $162,743,080 | |
| 8 | BBIO |
BridgeBio Pharma, Inc.
|
1,976,094 | $146,744,740 |
All Filings in IONS
Export CSV
25 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $118,887,443 | 1,583,266 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $121,975,041 | 1,541,841 | Shares | Sole | 2026-02-13 | |
| 2025-09-30 | $99,435,194 | 1,519,951 | Shares | Sole | 2025-11-10 | |
| 2025-06-30 | $58,783,689 | 1,487,818 | Shares | Sole | 2025-08-12 | |
| 2025-03-31 | $43,554,286 | 1,443,629 | Shares | Sole | 2025-09-15 | |
| 2024-12-31 | $51,791,142 | 1,481,440 | Shares | Sole | 2025-02-06 | |
| 2024-09-30 | $57,807,381 | 1,443,020 | Shares | Sole | 2024-11-12 | |
| 2024-06-30 | $63,297,531 | 1,328,106 | Shares | Sole | 2024-08-12 | |
| 2024-03-31 | $56,414,302 | 1,301,368 | Shares | Sole | 2024-05-09 | |
| 2023-12-31 | $64,518,388 | 1,275,319 | Shares | Sole | 2024-02-06 | |
| 2023-09-30 | $56,351,045 | 1,242,307 | Shares | Sole | 2023-11-08 | |
| 2023-06-30 | $49,203,996 | 1,199,220 | Shares | Sole | 2023-08-10 | |
| 2023-03-31 | $42,401,685 | 1,186,393 | Shares | Sole | 2023-05-12 | |
| 2022-12-31 | $47,449,242 | 1,256,268 | Shares | Sole | 2023-02-13 | |
| 2022-09-30 | $53,179,763 | 1,202,346 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $42,722,005 | 1,154,025 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $42,145,112 | 1,137,827 | Shares | Sole | 2022-05-13 | |
| 2021-12-31 | $33,273,348 | 1,093,439 | Shares | Sole | 2022-02-11 | |
| 2021-09-30 | $35,878,811 | 1,069,732 | Shares | Sole | 2021-11-16 | |
| 2021-06-30 | $28,479,864 | 713,960 | Shares | Sole | 2021-08-16 | |
| 2021-03-31 | $31,314,460 | 696,496 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $39,092,264 | 691,409 | Shares | Sole | 2021-02-16 | |
| 2020-09-30 | $32,323,129 | 681,204 | Shares | Sole | 2020-11-13 | |
| 2020-06-30 | $36,347,012 | 616,469 | Shares | Sole | 2020-08-20 | |
| 2020-03-31 | $28,873,848 | 610,699 | Shares | Sole | 2020-05-15 | |
| No filing history on record for this holder in this stock. | ||||||