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MAZE

Maze Therapeutics, Inc.
$31.26 +1.45 (+4.86%) At close · Jul 2
Market Cap
$1.73B
Shares
55,345,261

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Holders: 168
Total Value: $1,550,153,140
Total Shares: 51,931,432
Showing 1–100 of 176 holdings by value · page 1 of 2

Institutional Ownership Trend

5 quarters

Holder Concentration

Across 168 13F filers · Δ vs Dec 31, 2025
Top Holder
8.8%
Mar 2025 → Mar 2026 · range 8.8% – 15.6%
−0.6 pts
Top 5
37.5%
Mar 2025 → Mar 2026 · range 37.5% – 54.6%
−4.9 pts
Top 10
56.9%
Mar 2025 → Mar 2026 · range 56.9% – 76.9%
−3.4 pts
HHI
422
Mar 2025 → Mar 2026 · range 422 – 780
Broadly held−56

Quarterly Activity

vs Dec 31, 2025
New
50
Increased
59
Decreased
36
Sold Out
29
Unchanged
23
Holder count: +21
Institutional value: -31.0%
Shares held: -4.3%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Mega CITADEL ADVISORS LLC +360,997 809,214
Mid Logos Global Management LP +285,000 1,235,000
Mega BlackRock, Inc. +283,270 2,570,425
Large Balyasny Asset Management L.P. +261,939 461,151
Large Driehaus Capital Management LLC +258,147 636,162

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Mid Deep Track Capital, LP −768,878 3,477,562
Large MARSHALL WACE, LLP −536,833 310,639
Large Woodline Partners LP −385,000 650,229
Small Foresite Capital Management IV, LLC −365,756 156,901
Mega JANUS HENDERSON GROUP PLC −283,711 2,858,876

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
Mid Paradigm Biocapital Advisors LP 2,744,399 $81,920,310
Mega VANGUARD CAPITAL MANAGEMENT LLC 1,435,656 $42,854,331
Large ADAGE CAPITAL PARTNERS GP, L.L.C. 1,178,000 $35,163,300
Mid Cormorant Asset Management, LP 750,000 $22,387,500
Large FARALLON CAPITAL MANAGEMENT LLC 373,000 $11,134,050

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
— Third Rock Ventures IV, L.P. 4,473,958 $185,356,079
Mega VANGUARD GROUP INC 1,697,015 $70,307,330
— Alphabet Holdings LLC 1,388,583 $57,528,993
Mid Bellevue Group AG 887,708 $36,777,742
Micro Matrix Capital Management Company, LP 480,000 $19,886,400
Filter: New 50 Increased 59 Reduced 36 Sold out 29 Unchanged 23
Showing 100 of 176
All Common Calls Puts
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Holder Value (USD) % of 13F Shares Open
Mid Frazier Life Sciences Management, L.P. $136,333,128 8.79% 4,567,274
Small TRV GP IV, LLC $133,547,646 8.62% 4,473,958
Small ARCH Venture Management, LLC $122,983,582 7.93% 4,120,053
Mid Deep Track Capital, LP $103,805,225 6.70% 3,477,562
Mega JANUS HENDERSON GROUP PLC $85,337,448 5.51% 2,858,876
Mid Paradigm Biocapital Advisors LP $81,920,310 5.28% 2,744,399
Mega BlackRock, Inc. $76,727,183 4.95% 2,570,425
Mid a16z Capital Management, L.L.C. $50,811,416 3.28% 1,702,225
Mid Venrock Adviser, LLC $47,820,714 3.08% 1,602,034
Mega VANGUARD CAPITAL MANAGEMENT LLC $42,854,331 2.76% 1,435,656
Mid Alphabet Inc. $41,449,202 2.67% 1,388,583
Mid Logos Global Management LP $36,864,750 2.38% 1,235,000
Large ADAGE CAPITAL PARTNERS GP, L.L.C. $35,163,300 2.27% 1,178,000
Small General Catalyst Group Management, LLC $30,921,913 1.99% 1,035,910
Small TRV GP V, LLC $28,381,380 1.83% 950,800
Mega FMR LLC $25,796,787 1.66% 864,214
Mega CITADEL ADVISORS LLC $23,155,062 1.49% 775,714
Mid ArrowMark Colorado Holdings LLC $22,906,382 1.48% 767,383
Mid Casdin Capital, LLC $22,651,881 1.46% 758,857
Mid Cormorant Asset Management, LP $22,387,500 1.44% 750,000
Large Woodline Partners LP $19,409,335 1.25% 650,229
Mega STATE STREET CORP $19,006,151 1.23% 636,722
Large Driehaus Capital Management LLC $18,989,435 1.23% 636,162
Mid Caligan Partners LP $18,356,615 1.18% 614,962
Mega GEODE CAPITAL MANAGEMENT, LLC $17,909,014 1.16% 599,967
Large BESSEMER GROUP INC $14,381,431 0.93% 481,790
Large Balyasny Asset Management L.P. $13,765,357 0.89% 461,151
Mid Ikarian Capital, LLC $11,313,120 0.73% 378,999
Large FARALLON CAPITAL MANAGEMENT LLC $11,134,050 0.72% 373,000
Mid HHLR ADVISORS, LTD. $10,925,935 0.70% 366,028
Large MARSHALL WACE, LLP $9,272,574 0.60% 310,639
Mid BOOTHBAY FUND MANAGEMENT, LLC $8,491,608 0.55% 284,476
Small WASHINGTON UNIVERSITY Endowment $8,381,939 0.54% 280,802
Mega GOLDMAN SACHS GROUP INC $8,349,433 0.54% 279,713
Large Candriam S.C.A. $8,303,284 0.54% 278,167
Small Squadron Capital Management LLC $7,686,375 0.50% 257,500
Small Mass General Brigham, Inc $7,163,820 0.46% 239,994
Large Freestone Grove Partners LP $7,013,347 0.45% 234,953
Small SPHERA FUNDS MANAGEMENT LTD. $6,786,188 0.44% 227,343
Large Aberdeen Group plc $6,752,875 0.44% 226,227
Mega NORTHERN TRUST CORP Bank $6,309,751 0.41% 211,382
Mega MORGAN STANLEY $6,114,203 0.39% 204,831
Small Spruce Street Capital LP $5,970,000 0.39% 200,000
Mega BANK OF AMERICA CORP /DE/ Bank $5,823,257 0.38% 195,084
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $5,565,025 0.36% 186,433
Large Ensign Peak Advisors, Inc $5,545,950 0.36% 185,794
Small Foresite Capital Management IV, LLC $4,683,494 0.30% 156,901
Mega VANGUARD FIDUCIARY TRUST CO Bank $4,507,350 0.29% 151,000
Large Holocene Advisors, LP $4,064,614 0.26% 136,168
Large Qube Research & Technologies Ltd $4,028,257 0.26% 134,950
Mega PRICE T ROWE ASSOCIATES INC /MD/ $3,662,445 0.24% 122,695
Small Atika Capital Management LLC $3,328,273 0.21% 111,500
Mega AMERIPRISE FINANCIAL INC $3,208,457 0.21% 107,486
Large Alyeska Investment Group, L.P. $2,985,000 0.19% 100,000
Mid Integral Health Asset Management, LLC $2,985,000 0.19% 100,000
Small Ally Bridge Group (NY) LLC $2,985,000 0.19% 100,000
Small HighVista Strategies LLC $2,980,522 0.19% 99,850
Large Caption Management, LLC $2,895,450 0.19% 97,000
Mega UBS Group AG $2,802,854 0.18% 93,898
Small Exome Asset Management LLC $2,642,023 0.17% 88,510
Mega Invesco Ltd. $2,579,604 0.17% 86,419
Mid SummitTX Capital, L.P. $2,499,937 0.16% 83,750
Mega Bank of New York Mellon Corp Bank $2,216,898 0.14% 74,268
Mega RAYMOND JAMES FINANCIAL INC $2,070,842 0.13% 69,375
Mega ALLIANCEBERNSTEIN L.P. $1,933,145 0.12% 64,762
Mega Nuveen, LLC $1,891,295 0.12% 63,360
Mega WELLINGTON MANAGEMENT GROUP LLP $1,808,520 0.12% 60,587
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,799,955 0.12% 60,300
Large OSAIC HOLDINGS, INC. $1,789,298 0.12% 59,943
Mega FRANKLIN RESOURCES INC $1,780,164 0.11% 59,637
Mega JPMORGAN CHASE & CO $1,744,612 0.11% 58,446
Mid ADAR1 Capital Management, LLC $1,495,335 0.10% 50,095
Mega D. E. Shaw & Co., Inc. $1,362,233 0.09% 45,636
Small Propel Bio Management, LLC $1,307,370 0.08% 43,798
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,265,640 0.08% 42,400
Large ALPS ADVISORS INC $1,169,254 0.08% 39,171
Mega SCHRODER INVESTMENT MANAGEMENT GROUP $1,109,852 0.07% 37,181
Small DAFNA Capital Management LLC $1,044,750 0.07% 35,000
Mid Aquatic Capital Management LLC $1,044,063 0.07% 34,977
Large Russell Investments Group, Ltd. $970,898 0.06% 32,526
Small Parkman Healthcare Partners LLC $950,543 0.06% 31,844
Mega RHUMBLINE ADVISERS $940,663 0.06% 31,513
Small TWINBEECH CAPITAL LP $925,021 0.06% 30,989
Small Seven Fleet Capital Management LP $916,603 0.06% 30,707
Large NOMURA HOLDINGS INC $892,515 0.06% 29,900
Large NOMURA HOLDINGS INC $892,515 0.06% 29,900
Mega MILLENNIUM MANAGEMENT LLC $892,276 0.06% 29,892
Large Walleye Capital LLC $834,158 0.05% 27,945
Mega AQR CAPITAL MANAGEMENT LLC $834,156 0.05% 27,945
Mid XTX Topco Ltd $801,591 0.05% 26,854
Small Foresite Capital Management V, LLC $773,264 0.05% 25,905
Mega FIRST TRUST ADVISORS LP $760,727 0.05% 25,485
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $755,234 0.05% 25,301
Large Blackstone Inc. $745,951 0.05% 24,990
Mega CITADEL ADVISORS LLC $743,265 0.05% 24,900
Mid Y-Intercept (Hong Kong) Ltd $648,580 0.04% 21,728
Mega DEUTSCHE BANK AG\ Bank $604,850 0.04% 20,263
Mega JANE STREET GROUP, LLC $582,075 0.04% 19,500
Small ACUTA CAPITAL PARTNERS, LLC $577,149 0.04% 19,335
Large Verition Fund Management LLC $571,149 0.04% 19,134
Key facts CIK 1842295 CUSIP 578784100 Visit website Investor relations

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