RKDA

The options were granted on 5/9/2025 and the vesting occurs as follows, subject to the Participant's continued service: (1) 25% of the shares vest on the first anniversary of the date of the award and (2) 75% of the shares vest in 36 equal installments, the first installment occurring on the last day of the month in which the initial vesting date occurs.

The options were granted on 5/9/2025 and the vesting occurs as follows, subject to the Participant's continued service: (1) 25% of the shares vest on the first anniversary of the date of the award and (2) 75% of the shares vest in 36 equal installments, the first installment occurring on the last day of the month in which the initial vesting date occurs.

Reflects the purchase of 700 shares of the Issuer's common stock on 2/3/25 at a per share purchase price of $2.49 pursuant to participation in the Issuer's 2015 Employee Stock Purchase Plan ("ESPP"). This transaction is exempt from Rule 16b-3(c). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of Issuer's common stock.

The amount includes the 2015 Employee Stock Purchase Plan ("ESPP") purchases, for the purchase periods from February 1, 2021 to February 1, 2025. These transactions were exempt from Rule 16b-3(c). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of Issuer's Common Stock on the respective offering date or purchase date, whichever is lower.

Reflects the purchase of 700 shares of the Issuer's common stock on 2/3/25 at a per share purchase price of $2.49 pursuant to participation in the Issuer's 2015 Employee Stock Purchase Plan ("ESPP"). This transaction is exempt from Rule 16b-3(c). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of Issuer's common stock.

The amount includes the 2015 Employee Stock Purchase Plan ("ESPP") purchases, for the purchase periods from August 1, 2022 to February 1, 2025. These transactions were exempt from Rule 16b-3(c). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of Issuer's Common Stock on the respective offering date or purchase date, whichever is lower.

The options were granted on 8/19/2024 and the vesting occurs as follows, subject to the Participant's continued service: (1) 25% of the shares vest on the first anniversary of the date of the award and (2) 75% of the shares vest in 36 equal installments, the first installment occurring on the last day of the month in which the initial vesting date occurs.

The Option will become 100% vested and exercisable on the earlier to occur of (i) August 19, 2025 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The options were granted on 8/19/2024 and the vesting occurs as follows, subject to the Participant's continued service: (1) 25% of the shares vest on the first anniversary of the date of the award and (2) 75% of the shares vest in 36 equal installments, the first installment occurring on the last day of the month in which the initial vesting date occurs.

The Option will become 100% vested and exercisable on the earlier to occur of (i) August 19, 2025 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) August 19, 2025 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) August 19, 2025 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) August 19, 2025 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) August 19, 2025 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

Reflects the purchase of 700 shares of the Issuer's common stock on 8/1/24 at a per share purchase price of $2.06 pursuant to participation in the Issuer's 2015 Employee Stock Purchase Plan ("ESPP"). This transaction is exempt from Rule 16b-3(c). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of Issuer's common stock.

The amount includes the 2015 Employee Stock Purchase Plan ("ESPP") purchases, for the purchase periods from February 1, 2022 to August 1, 2024. These transactions were exempt from Rule 16b-3(c). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of Issuer's Common Stock on the date of each respective purchase.

Reflects the purchase of 700 shares of the Issuer's common stock on 8/1/24 at a per share purchase price of $2.06 pursuant to participation in the Issuer's 2015 Employee Stock Purchase Plan ("ESPP"). This transaction is exempt from Rule 16b-3(c). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of Issuer's common stock.

The amount includes the 2015 Employee Stock Purchase Plan ("ESPP") purchases, for the purchase periods from February 1, 2021 to August 1, 2024. These transactions were exempt from Rule 16b-3(c). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of Issuer's Common Stock on the date of each respective purchase.

Reflects the purchase of 700 shares of the Issuer's common stock on 2/1/24 at a per share purchase price of $2.06 pursuant to participation in the Issuer's 2015 Employee Stock Purchase Plan ("ESPP"). This transaction is exempt from Rule 16b-3(c). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of Issuer's common stock.

The amount includes the 2015 Employee Stock Purchase Plan ("ESPP") purchases, for the purchase periods from February 1, 2021 to February 1, 2024. These transactions were exempt from Rule 16b-3(c). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of Issuer's Common Stock on the date of each respective purchase.

Reflects the purchase of 649 shares of the Issuer's common stock on 8/1/23 at a per share purchase price of $3.67 pursuant to participation in the Issuer's 2015 Employee Stock Purchase Plan ("ESPP"). This transaction is exempt from Rule 16b-3(c). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of Issuer's common stock.

The amount includes the 2015 Employee Stock Purchase Plan ("ESPP") purchases, for the purchase periods from February 1, 2021 to August 1, 2023. These transactions were exempt from Rule 16b-3(c). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of Issuer's Common Stock on the date of each respective purchase.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 6, 2024 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 6, 2024 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 6, 2024 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 6, 2024 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 6, 2024 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 6, 2024 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

This transaction was executed in multiple trades at prices ranging from $4.27 to $4.35. The price reported above reflects the weighted average purchase price. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

The options were granted on 4/4/2023 and the vesting occurs as follows, subject to the Participant's continued service: (1) 25% of the shares vest on the first anniversary of the date of the award and (2) 75% of the shares vest in 36 equal installments, the first installment occurring on the last day of the month in which the initial vesting date occurs.

The options were granted on 4/4/2023 and the vesting occurs as follows, subject to the Participant's continued service: (1) 25% of the shares vest on the first anniversary of the date of the award and (2) 75% of the shares vest in 36 equal installments, the first installment occurring on the last day of the month in which the initial vesting date occurs.

The options were granted on 4/4/2023 and the vesting occurs as follows, subject to the Participant's continued service: (1) 25% of the shares vest on the first anniversary of the date of the award and (2) 75% of the shares vest in 36 equal installments, the first installment occurring on the last day of the month in which the initial vesting date occurs.

Reflects the purchase of 700 shares of the Issuer's common stock on 2/1/23 at a per share purchase price of $0.23 pursuant to participation in the Issuer's 2015 Employee Stock Purchase Plan ("ESPP"). This transaction is exempt from Rule 16b-3(c). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of Issuer's common stock.

The amount includes the 2015 Employee Stock Purchase Plan ("ESPP") purchases, for the purchase periods from February 1, 2021 to February 1, 2023. These transactions were exempt from Rule 16b-3(c). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of Issuer's Common Stock on the date of each respective purchase.

The options were granted on 1/3/2023 and the vesting occurs as follows, subject to the Participant's continued service: (1) 25% of the shares vest on the first anniversary of the date of the award and (2) 75% of the shares vest in 36 equal installments, the first installment occurring on the last day of the month in which the initial vesting date occurs.

The option vests in two equal installments occurring on the first, and second anniversary of the date of grant.

The option vests in two equal installments occurring on the first, and second anniversary of the date of grant.

Reflects the purchase of 700 shares of the Issuer's common stock on 8/1/22 at a per share purchase price of $0.70 pursuant to participation in the Issuer's 2015 Employee Stock Purchase Plan ("ESPP"). This transaction is exempt from Rule 16b-3(c). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of Issuer's common stock.

The amount includes the 2015 Employee Stock Purchase Plan ("ESPP") purchases, for the purchase period of August 4, 2020 to August 1, 2022. These transactions were exempt from Rule 16b-3(c). In accordance with the ESPP, these shares were purchased at a price equal to 85% of the closing price of Issuer's Common Stock on the date of each respective purchase.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 1, 2023 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 1, 2023 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 1, 2023 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 1, 2023 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 1, 2023 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 1, 2023 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option vests in two equal installments occurring on the first, and second anniversary of the date of grant, subject to the Participant's continued service.

25% of the total number of shares subject to the Option will vest on the first anniversary of the date of the award; the remaining 75% will vest in 36 equal installments, subject to the Participant's continued service.

The option vests in two equal installments occurring on the first, and second anniversary of the date of grant.

25% of the total number of shares subject to the Option will vest on the first anniversary of the date of the award; the remaining 75% will vest in 36 equal installments, subject to the Participant's continued service.

25% of the total number of shares subject to the Option will vest on the first anniversary of the date of the award; the remaining 75% will vest in 36 equal installments, subject to the Participant's continued service.

25% of the total number of shares subject to the Option will vest on the first anniversary of the date of the award; the remaining 75% will vest in 36 equal installments, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 2, 2022 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 2, 2022 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 2, 2022 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 2, 2022 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.

The Option will become 100% vested and exercisable on the earlier to occur of (i) June 2, 2022 or (ii) the date of the Issuer's next Annual Meeting of Stockholders, subject to the Participant's continued service.