Stocks
SPRO
CITADEL ADVISORS LLC

CITADEL ADVISORS LLC

CIK

0001423053

City

Chicago

State / Country

Stock

SPRO — Spero Therapeutics, Inc.

Holdings in SPRO

Position Over Time

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2025-12-31	$170,323	73,100	-81.6%	Shares	Defined	2026-02-17
2025-12-31	$927,022	397,864	+626.0%	Shares	Defined	2026-02-17
2025-09-30	$103,024	54,800	-47.2%	Shares	Defined	2025-11-14
2025-06-30	$300,979	103,786	-24.4%	Shares	Defined	2025-08-14
2025-06-30	$397,880	137,200	+1375.3%	Shares	Defined	2025-08-14
2025-03-31	$6,696	9,300	-84.8%	Shares	Defined	2025-05-15
2025-03-31	$44,147	61,316	+61216.0%	Shares	Defined	2025-05-15
2025-03-31	$72	100	-99.9%	Shares	Defined	2025-05-15
2024-12-31	$178,057	172,872	+86336.0%	Shares	Defined	2025-02-14
2024-12-31	$206	200	0.0%	Shares	Defined	2025-02-14
2024-12-31	$206	200	-99.8%	Shares	Defined	2025-02-14
2024-09-30	$109,109	81,425	+40612.5%	Shares	Defined	2024-11-14
2024-09-30	$268	200	0.0%	Shares	Defined	2024-11-14
2024-09-30	$268	200	-60.0%	Shares	Defined	2024-11-14
2024-06-30	$650	500	-99.8%	Shares	Defined	2024-08-14
2024-06-30	$405,644	312,034	+31103.4%	Shares	Defined	2024-08-14
2024-06-30	$1,300	1,000	-96.9%	Shares	Defined	2024-08-14
2023-12-31	$47,442	32,274	+32174.0%	Shares	Defined	2024-02-14
2023-06-30	$145	100	-99.3%	Shares	Defined	2023-08-14
2023-06-30	$21,686	14,956	+2392.7%	Shares	Defined	2023-08-14
2023-06-30	$870	600	-99.4%	Shares	Defined	2023-08-14
2022-06-30	$80,288	108,351	+165.6%	Shares	Defined	2022-08-15
2022-06-30	$30,232	40,800	+11.5%	Shares	Defined	2022-08-15
2022-06-30	$27,120	36,600	+239.0%	Shares	Defined	2022-08-15
2022-03-31	$93,933	10,797	-35.7%	Shares	Defined	2022-05-16
2022-03-31	$146,160	16,800	+7.7%	Shares	Defined	2022-05-16
2021-12-31	$249,756	15,600	-43.1%	Shares	Defined	2022-02-14
2021-12-31	$438,674	27,400	+5.0%	Shares	Defined	2022-02-14
2021-06-30	$364,356	26,100	+121.0%	Shares	Defined	2021-08-16
2021-06-30	$164,895	11,812	-69.2%	Shares	Defined	2021-08-16
2021-06-30	$534,668	38,300	+23.5%	Shares	Defined	2021-08-16
2021-03-31	$456,320	31,000	+54.4%	Shares	Defined	2021-05-21
2021-03-31	$295,577	20,080	-52.5%	Shares	Defined	2021-05-21
2021-03-31	$622,656	42,300	-34.1%	Shares	Defined	2021-05-21
2020-12-31	$1,244,838	64,200	+96.7%	Shares	Defined	2021-02-16
2020-12-31	$632,850	32,638	+4.3%	Shares	Defined	2021-02-16
2020-12-31	$606,907	31,300	+46.9%	Shares	Defined	2021-02-16
2020-09-30	$237,819	21,310	-23.1%	Shares	Defined	2020-11-16
2020-09-30	$309,132	27,700	+73.1%	Shares	Defined	2020-11-16
2020-09-30	$178,560	16,000	—	Shares	Defined	2020-11-16