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SPRO

Spero Therapeutics, Inc.
$2.19 -0.01 (-0.45%) At close · Jul 6
Market Cap
$126.80M
Shares
57,901,493

Price & Indicators

20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$2.19 Open$2.17 Day$2.15–2.21 52W$1.80–3.22 Avg vol 30d1.5M Short int1.8M · 3.2% float · 2.3d Short vol23% Last earningsMay 13, 2026 DataJan 2020–Jul 2026 Filing10-Q · May 13
Equibles Rating blended score · not investment advice
Overall
Sell
Technical · trend & momentum Sell
50 / 200-day cross no cross
Price vs 200-day avg −9% below
Price vs 50-day avg −15% below
RSI (14) 41 · neutral
MACD trend negative
52-week position 27% · mid-range
Sentiment · smart money Bearish
Trend (MA cross) 50d $3 › 200d $2 — 50d above 200d
Institutional flow -11% holders QoQ · +8 funds added
Insider flow Net -$63.4K over 90 days · 100% sells
Short interest 3.16% of float · ▲ +7.3% MoM · 2.3 days cover
Volume signal Volume near normal
Institution breadth 50 holders — mid 3-yr range
Fundamentals Strong
+ Revenue growth +39% Y/Y
+ EPS growth +112% Y/Y
Free cash flow $-12.8M
Valuation P/E 8.1 · in line
+ Balance sheet net cash $40.3M

Blended from price, positioning & fundamentals · daily-close · not investment advice.

Up next
Next earnings call
Aug 13, 2026 Est · unconfirmed · in 5 wks
FQ3-26 quarter ends
~Sep 30, 2026 Est
filed May 13, 2026

Technicals

trend & momentum for long-term holders Sell
3 · 3 · 0
50 / 200-day cross
no cross Neutral
Price vs 200-day avg
−9% below Bearish
Price vs 50-day avg
−15% below Bearish
RSI (14)
41 · neutral Neutral
MACD trend
negative Bearish
52-week position
27% · mid-range Neutral
Market signals — smart money & positioning
Bearish · 3 of 6
Trend (MA cross) No cross
50d $3 › 200d $2 — 50d above 200d
Institutional flow Distributing
-11% holders QoQ · +8 funds added
Insider flow Distributing
Net -$63.4K over 90 days · 100% sells
Short interest Rising
3.16% of float · ▲ +7.3% MoM · 2.3 days cover
Volume signal Normal
Volume near normal
Institution breadth Steady
50 holders — mid 3-yr range
Price context
position in its 52-week range
52-wk low $2 Now $2 · 27% 52-wk high $3
vs 200-day avg -9% vs 50-day avg -15%

Illustrative technical + ownership context — a signal mix, not investment advice.

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
SPRO
Spero Therapeutics, Inc.
this stock
$126.80M -6.0% -53.8% 8.1 3.2%
ONC
BeOne Medicines Ltd.
$488.96B +1.9% +22179.2% 995.1 0.1%
VRTX
Vertex Pharmaceuticals Inc / Ma
$132.92B +16.8% +46.2% 31.1 1.8%
REGN
Regeneron Pharmaceuticals, Inc.
$69.33B -15.7% +20.8% 16.1 3.2%
ARGX
Argenx SE
$57.49B +9.4% 2.4%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Reducing
Holders
50
% held
36.0%
Net QoQ
-413.9K sh
Top holder
GSK plc
Held Float
View
Held by Funds
Fund positions
19
View
Short & Settlement
Short Interest Rising
Shares short
1.8M
Days to cover
2.3d
Change
+125.2K sh
View
Short Volume
Short vol %
23%
As of
Jul 7, 2026
Short Total
View
Fails to Deliver
FTD shares
5.7K
Value
$15.3K
As of
Jun 12, 2026
View
Off-Exchange
Off-exchange %
51.6%
Week of
May 4, 2026
Off-exch Lit
View
Smart Money
Insider Trades Net selling
Net (90d)
-$63.4K
Buyers / Sellers
0 / 1
Buyers Sellers
View
Financials
Financials
Revenue (FY)
$66.8M
Net income (FY)
$8.6M
EPS diluted
$0.15
View
Filings
SEC Filings
Latest
8-K
Filed
Jun 25, 2026
This year
8
View
Proposed Sales
Value
$65.5K
Shares
45.1K
Filed
Feb 5, 2024
View
Exempt Offerings
Offering
$9.0M
Filed
Nov 15, 2022
View
Earnings & Events
Earnings Calls
Last call
May 13, 2026
View

Performance

5D 20D 120D MTD YTD
SPRO -3.1% -26.5% -14.1% -0.9% -6.0%
SPY +3.1% -0.8% +8.2% +0.6% +10.2%
vs SPY -6.2% -25.7% -22.4% -1.5% -16.2%
Key facts CIK 1701108 CUSIP 84833T103 Visit website Investor relations