Stocks
AMLX Amylyx Pharmaceuticals, Inc.

AMLX

Amylyx Pharmaceuticals, Inc.

Company with tickers: AMLX

CIK

1658551

CUSIP

03237H101

Shares Outstanding

111,186,317

13F Activity (30d)

153 filings 151 filers

Price

$13.74

Market Cap

$1.51B

P/E Ratio

-8.98

EPS (Diluted)

$-1.53

52W High

$18.61

52W Low

$4.64

Price History Institutional Holders Short Volume Short Interest Fails to Deliver Financials SEC Filings Earnings Calls Insider Trades Congressional Trades

Date	Insider	Role	Type	Shares	Price	Value	After
2026-03-05	Cohen Joshua B	Director, Co-Chief Executive Officer	Award	248,865	—	—	3,583,548
2026-03-05	Cohen Joshua B	Director, Co-Chief Executive Officer	Award	373,295	—	—	373,295
2026-03-05	Mazzariello Gina	Chief Legal Officer	Award	74,660	—	—	209,090
2026-03-05	Mazzariello Gina	Chief Legal Officer	Award	111,990	—	—	111,990
2026-03-05	FRATES JAMES M	Chief Financial Officer	Award	95,990	—	—	261,628
2026-03-05	FRATES JAMES M	Chief Financial Officer	Other	15,459	—	—	15,459
2026-03-05	FRATES JAMES M	Chief Financial Officer	Other	100,000	—	—	100,000
2026-03-05	Klee Justin B.	Director, Co-Chief Executive Officer	Award	248,865	—	—	3,583,481
2026-03-05	Klee Justin B.	Director, Co-Chief Executive Officer	Award	373,295	—	—	373,295
2026-03-05	Bedrosian Camille L	Director	Award	95,990	—	—	265,285
2026-03-05	Bedrosian Camille L	Director	Award	143,985	—	—	143,985
2026-03-05	FRATES JAMES M	Chief Financial Officer	Award	143,985	—	—	143,985
2026-03-05	FRATES JAMES M	Chief Financial Officer	Other	11,072	—	—	11,072
2026-03-02	Cohen Joshua B	Director, Co-Chief Executive Officer	Sell	29,282	$14.48	$424,120	3,334,683
2026-03-02	FRATES JAMES M	Chief Financial Officer	Sell	7,909	$14.52	$114,851	165,638
2026-03-02	FRATES JAMES M	Chief Financial Officer	Other	15,459	—	—	15,459
2026-03-02	FRATES JAMES M	Chief Financial Officer	Other	11,072	—	—	11,072
2026-03-02	FRATES JAMES M	Chief Financial Officer	Other	100,000	—	—	100,000
2026-03-02	Mazzariello Gina	Chief Legal Officer	Sell	6,844	$14.52	$99,378	134,430
2026-03-02	Klee Justin B.	Director, Co-Chief Executive Officer	Sell	29,282	$14.47	$423,760	3,334,616
2026-03-02	Bedrosian Camille L	Director	Sell	6,461	$14.58	$94,205	169,295
2026-02-23	Mazzariello Gina	Chief Legal Officer	Sell	3,419	$14.14	$48,352	141,274
2026-02-02	FRATES JAMES M	Chief Financial Officer	Other	15,459	—	—	15,459
2026-02-02	FRATES JAMES M	Chief Financial Officer	Other	100,000	—	—	100,000
2026-02-02	FRATES JAMES M	Chief Financial Officer	Other	11,072	—	—	11,072
2026-02-02	FRATES JAMES M	Chief Financial Officer	Sell	3,557	$14.65	$52,097	173,547
2026-02-02	Cohen Joshua B	Director, Co-Chief Executive Officer	Sell	15,500	$14.68	$227,593	3,363,965
2026-02-02	Mazzariello Gina	Chief Legal Officer	Sell	3,448	$14.65	$50,516	144,693
2026-02-02	Klee Justin B.	Director, Co-Chief Executive Officer	Sell	15,500	$14.69	$227,618	3,363,898
2026-01-16	Cohen Joshua B	Director, Co-Chief Executive Officer	Convert	2,818	$7.57	$21,332	3,381,439
2026-01-16	Cohen Joshua B	Director, Co-Chief Executive Officer	Sell	1,974	$13.83	$27,299	3,379,465
2026-01-16	Cohen Joshua B	Director, Co-Chief Executive Officer	Convert	2,818	—	—	0
2026-01-16	Klee Justin B.	Director, Co-Chief Executive Officer	Convert	2,847	$7.57	$21,552	3,381,393
2026-01-16	Klee Justin B.	Director, Co-Chief Executive Officer	Sell	1,995	$13.89	$27,701	3,379,398
2026-01-16	Klee Justin B.	Director, Co-Chief Executive Officer	Convert	2,847	—	—	0
2026-01-15	Cohen Joshua B	Director, Co-Chief Executive Officer	Convert	197,182	$7.57	$1,492,668	3,514,814
2026-01-15	Cohen Joshua B	Director, Co-Chief Executive Officer	Sell	136,193	$13.59	$1,850,795	3,378,621
2026-01-15	Cohen Joshua B	Director, Co-Chief Executive Officer	Convert	197,182	—	—	2,818
2026-01-15	Klee Justin B.	Director, Co-Chief Executive Officer	Convert	197,153	—	—	2,847
2026-01-15	Klee Justin B.	Director, Co-Chief Executive Officer	Sell	136,193	$13.58	$1,849,869	3,378,546
2026-01-15	Klee Justin B.	Director, Co-Chief Executive Officer	Convert	197,153	$7.57	$1,492,448	3,514,739
2026-01-12	MILNE GEORGE M JR	Director	Gift	17,780	—	—	812,881
2026-01-06	FRATES JAMES M	Chief Financial Officer	Other	100,000	—	—	100,000
2026-01-06	FRATES JAMES M	Chief Financial Officer	Other	15,459	—	—	15,459
2026-01-06	FRATES JAMES M	Chief Financial Officer	Sell	3,326	$11.11	$36,954	177,104
2026-01-06	FRATES JAMES M	Chief Financial Officer	Other	11,072	—	—	11,072
2026-01-06	Cohen Joshua B	Director, Co-Chief Executive Officer	Sell	7,715	$11.09	$85,596	3,317,632
2026-01-06	Klee Justin B.	Director, Co-Chief Executive Officer	Sell	7,715	$11.09	$85,589	3,317,586
2025-12-23	Firestone Karen	Director	Buy	8,100	$12.45	$100,845	63,100
2025-12-01	Bedrosian Camille L	Director	Sell	6,580	$14.35	$94,418	175,756
2025-09-30	Cohen Joshua B	Director, Co-Chief Executive Officer	Sell	29,733	$14.34	$426,469	3,325,547
2025-09-30	Cohen Joshua B	Director, Co-Chief Executive Officer	Sell	200	$15.00	$3,000	3,325,347
2025-09-30	Klee Justin B.	Director, Co-Chief Executive Officer	Sell	200	$15.01	$3,002	3,325,301
2025-09-30	Klee Justin B.	Director, Co-Chief Executive Officer	Sell	29,775	$14.37	$427,950	3,325,501
2025-09-30	Mazzariello Gina	Chief Legal Officer	Sell	8,828	$14.58	$128,669	148,141
2025-09-30	FRATES JAMES M	Chief Financial Officer	Sell	10,558	$14.65	$154,650	280,430
2025-09-30	FRATES JAMES M	Chief Financial Officer	Other	15,459	—	—	15,459
2025-09-30	FRATES JAMES M	Chief Financial Officer	Other	11,072	—	—	11,072
2025-09-30	Bedrosian Camille L	Director	Sell	12,039	$14.58	$175,518	182,336
2025-08-13	Mazzariello Gina	Chief Legal Officer	Sell	15,000	$8.34	$125,046	156,969
2025-08-12	Mazzariello Gina	Chief Legal Officer	Sell	15,000	$8.07	$121,103	171,969
2025-06-05	Firestone Karen	Director	Award	25,000	—	—	25,000
2025-06-05	Quimi Daphne	Chief Financial Officer	Award	25,000	—	—	25,000
2025-06-05	MILNE GEORGE M JR	Director	Award	25,000	—	—	25,000
2025-06-05	Zeiher Bernhardt G	Director	Award	25,000	—	—	25,000
2025-06-05	FONTEYNE PAUL R.	Director	Award	25,000	—	—	25,000
2025-05-22	Mazzariello Gina	Chief Legal Officer	Gift	1,000	—	—	186,969
2025-03-31	Mazzariello Gina	Chief Legal Officer	Sell	9,192	$3.48	$31,954	187,969
2025-03-31	Cohen Joshua B	Director, Co-Chief Executive Officer	Sell	21,490	$3.47	$74,482	3,355,280
2025-03-31	Klee Justin B.	Director, Co-Chief Executive Officer	Sell	21,490	$3.46	$74,454	3,355,276
2025-03-31	FRATES JAMES M	Chief Financial Officer	Other	15,459	—	—	15,459
2025-03-31	FRATES JAMES M	Chief Financial Officer	Sell	10,896	$3.47	$37,806	290,988
2025-03-31	FRATES JAMES M	Chief Financial Officer	Other	11,072	—	—	11,072
2025-03-31	Bedrosian Camille L	Director	Sell	12,425	$3.47	$43,082	194,375
2025-03-20	Zeiher Bernhardt G	Director	Buy	10,000	$3.70	$37,005	10,000
2025-03-06	Klee Justin B.	Director, Co-Chief Executive Officer	Award	180,118	—	—	3,376,766
2025-03-06	Klee Justin B.	Director, Co-Chief Executive Officer	Award	270,177	—	—	270,177
2025-03-06	Bedrosian Camille L	Director	Award	68,420	—	—	206,800
2025-03-06	Bedrosian Camille L	Director	Award	102,630	—	—	102,630
2025-03-06	Cohen Joshua B	Director, Co-Chief Executive Officer	Award	180,118	—	—	3,376,770
2025-03-06	Cohen Joshua B	Director, Co-Chief Executive Officer	Award	270,177	—	—	270,177
2025-03-06	FRATES JAMES M	Chief Financial Officer	Other	11,072	—	—	11,072
2025-03-06	FRATES JAMES M	Chief Financial Officer	Award	102,630	—	—	102,630
2025-03-06	FRATES JAMES M	Chief Financial Officer	Award	68,420	—	—	301,884
2025-03-06	FRATES JAMES M	Chief Financial Officer	Other	15,459	—	—	15,459
2025-03-06	Mazzariello Gina	Chief Legal Officer	Award	63,851	—	—	197,161
2025-03-06	Mazzariello Gina	Chief Legal Officer	Award	95,777	—	—	95,777
2025-03-03	Klee Justin B.	Director, Co-Chief Executive Officer	Sell	4,595	$3.15	$14,483	3,196,648
2025-03-03	Cohen Joshua B	Director, Co-Chief Executive Officer	Sell	4,595	$3.17	$14,549	3,196,652
2025-03-03	Mazzariello Gina	Chief Legal Officer	Sell	1,611	$3.12	$5,022	133,310
2025-02-24	Mazzariello Gina	Chief Legal Officer	Sell	4,169	$3.15	$13,145	134,921
2025-02-05	Klee Justin B.	Director, Co-Chief Executive Officer	Convert	36,310	$1.57	$57,007	3,201,243
2025-02-05	Klee Justin B.	Director, Co-Chief Executive Officer	Convert	36,310	—	—	0
2025-02-03	Mazzariello Gina	Chief Legal Officer	Sell	3,678	$3.49	$12,839	139,090
2025-02-03	Cohen Joshua B	Director, Co-Chief Executive Officer	Sell	11,851	$3.47	$41,108	3,201,247
2025-02-03	Klee Justin B.	Director, Co-Chief Executive Officer	Sell	11,855	$3.47	$41,104	3,164,933
2025-01-24	MILNE GEORGE M JR	Director	Gift	27,910	—	—	830,661
2025-01-06	Klee Justin B.	Director, Co-Chief Executive Officer	Sell	7,471	$4.04	$30,202	3,176,788
2025-01-06	Cohen Joshua B	Director, Co-Chief Executive Officer	Sell	7,471	$4.05	$30,232	3,213,098
2024-12-02	Bedrosian Camille L	Director	Sell	5,421	$5.54	$30,007	138,380