RA CAPITAL MANAGEMENT, L.P.

CIK

1346824

City

BOSTON

State / Country

Stock

ASND — Ascendis Pharma A/S

Top Portfolio Positions

84 positions · $9,431,068,368 total · as of Mar 31, 2026

Ticker	Company	Shares	Value (USD)	% of Portfolio
ASND	Ascendis Pharma A/S Healthcare	10,281,496	$2,351,686,580	24.94%
PCVX	Vaxcyte, Inc. Healthcare	11,474,599	$666,788,947	7.07%
RYTM	Rhythm Pharmaceuticals, Inc. Healthcare	6,666,837	$579,814,813	6.15%
TYRA	Tyra Biosciences, Inc. Healthcare	12,198,625	$467,207,337	4.95%
SION	Sionna Therapeutics, Inc. Healthcare	9,905,045	$397,093,254	4.21%
EWTX	Edgewise Therapeutics, Inc. Healthcare	10,428,437	$328,495,765	3.48%
NAMS	NewAmsterdam Pharma Co N.V. Healthcare	9,550,191	$305,701,613	3.24%
NUVL	Nuvalent, Inc. Healthcare	2,534,145	$259,623,155	2.75%
DNTH	Dianthus Therapeutics, Inc. /DE/ Healthcare	2,611,733	$219,176,633	2.32%
MLYS	Mineralys Therapeutics, Inc. Healthcare	7,692,750	$208,396,597	2.21%

25 quarters · across all stocks

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23 of 23 shown

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$2,351,686,580	10,281,496	0.0%	Shares	Sole	2026-05-15
2025-12-31	$2,192,426,207	10,281,496	0.0%	Shares	Sole	2026-02-17
2025-09-30	$2,044,064,219	10,281,496	0.0%	Shares	Sole	2025-11-14
2025-06-30	$1,774,586,209	10,281,496	0.0%	Shares	Sole	2025-08-14
2025-03-31	$1,602,473,966	10,281,496	+1.7%	Shares	Sole	2025-05-15
2024-12-31	$1,392,221,466	10,112,744	+4.1%	Shares	Sole	2025-02-14
2024-09-30	$1,449,864,004	9,710,428	-3.9%	Shares	Sole	2024-11-14
2024-06-30	$1,378,583,592	10,108,400	+0.0%	Shares	Sole	2024-08-14
2023-12-31	$1,273,027,030	10,107,400	-10.0%	Shares	Sole	2024-02-14
2023-06-30	$1,001,863,112	11,225,357	+61.3%	Shares	Sole	2023-08-14
2023-03-31	$745,948,732	6,957,179	0.0%	Shares	Sole	2023-05-15
2022-12-31	$849,680,271	6,957,179	-8.1%	Shares	Sole	2023-02-14
2022-09-30	$781,461,354	7,567,900	0.0%	Shares	Sole	2022-11-14
2022-06-30	$703,511,984	7,567,900	0.0%	Shares	Sole	2022-08-15
2022-03-31	$888,168,744	7,567,900	0.0%	Shares	Sole	2022-05-16
2021-12-31	$1,018,109,587	7,567,900	+2.4%	Shares	Sole	2022-02-14
2021-09-30	$1,177,557,381	7,387,900	+8.5%	Shares	Sole	2021-11-15
2021-06-30	$895,374,158	6,806,341	+6.1%	Shares	Sole	2021-08-16
2021-03-31	$826,407,944	6,412,228	+9.3%	Shares	Sole	2021-05-17
2020-12-31	$978,221,071	5,865,338	-0.8%	Shares	Sole	2021-02-16
2020-09-30	$911,991,385	5,909,742	+20.2%	Shares	Sole	2020-11-16
2020-06-30	$726,921,844	4,914,955	0.0%	Shares	Sole	2020-08-14
2020-03-31	$553,473,082	4,914,955	—	Shares	Sole	2020-05-15
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