RA CAPITAL MANAGEMENT, L.P.

Position in RYTM — Rhythm Pharmaceuticals, Inc.

CIK 1346824 BOSTON, MA

Position in RYTM

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$579,814,813

-$133,803,419 QoQ

Shares Held

6,666,837

0.0% QoQ

Ownership

9.73%

of shares outstanding

% of Portfolio

6.15%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Mar 2020

23 quarters on record

Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Healthcare · as of Mar 31, 2026

RA CAPITAL MANAGEMENT, L.P. holds $9,134,713,488 across 74 Biotechnology names. RYTM ranks #3 (6.3% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	ASND	Ascendis Pharma A/S	10,281,496	$2,351,686,580
2	PCVX	Vaxcyte, Inc.	11,474,599	$666,788,947
3	RYTM	Rhythm Pharmaceuticals, Inc. This page	6,666,837	$579,814,813
4	TYRA	Tyra Biosciences, Inc.	12,198,625	$467,207,337
5	SION	Sionna Therapeutics, Inc.	9,905,045	$397,093,254
6	EWTX	Edgewise Therapeutics, Inc.	10,428,437	$328,495,765
7	NAMS	NewAmsterdam Pharma Co N.V.	9,550,191	$305,701,613
8	NUVL	Nuvalent, Inc.	2,534,145	$259,623,155

23 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$579,814,813	6,666,837	0.0%	Shares	Sole	2026-05-15
2025-12-31	$713,618,232	6,666,837	+17.3%	Shares	Sole	2026-02-17
2025-09-30	$573,760,445	5,681,359	+2.2%	Shares	Sole	2025-11-14
2025-06-30	$351,422,275	5,561,359	-8.6%	Shares	Sole	2025-08-14
2025-03-31	$322,291,303	6,084,412	0.0%	Shares	Sole	2025-05-15
2024-12-31	$340,605,383	6,084,412	0.0%	Shares	Sole	2025-02-14
2024-09-30	$318,762,344	6,084,412	0.0%	Shares	Sole	2024-11-14
2024-06-30	$249,825,956	6,084,412	+14.1%	Shares	Sole	2024-08-14
2023-12-31	$245,039,039	5,330,412	-6.1%	Shares	Sole	2024-02-14
2023-06-30	$93,598,344	5,676,067	+2.9%	Shares	Sole	2023-08-14
2023-03-31	$98,406,635	5,516,067	0.0%	Shares	Sole	2023-05-15
2022-12-31	$160,627,871	5,516,067	+0.8%	Shares	Sole	2023-02-14
2022-09-30	$134,041,141	5,471,067	+12.3%	Shares	Sole	2022-11-14
2022-06-30	$20,214,928	4,871,067	0.0%	Shares	Sole	2022-08-15
2022-03-31	$56,114,691	4,871,067	0.0%	Shares	Sole	2022-05-16
2021-12-31	$48,613,248	4,871,067	0.0%	Shares	Sole	2022-02-14
2021-09-30	$63,616,135	4,871,067	0.0%	Shares	Sole	2021-11-15
2021-06-30	$95,375,491	4,871,067	0.0%	Shares	Sole	2021-08-16
2021-03-31	$103,607,595	4,871,067	+16.6%	Shares	Sole	2021-05-17
2020-12-31	$124,243,661	4,179,067	-18.7%	Shares	Sole	2021-02-16
2020-09-30	$111,392,641	5,140,408	-1.3%	Shares	Sole	2020-11-16
2020-06-30	$116,184,962	5,210,088	-3.9%	Shares	Sole	2020-08-14
2020-03-31	$82,527,588	5,422,312	—	Shares	Sole	2020-05-15
No filing history on record for this holder in this stock.