RA CAPITAL MANAGEMENT, L.P.
Filing Date
Global Rank
#443
/ 8,700
▲ 69
Top Industry
Biotechnology
97.6%
Period ended 2 months ago
Filed Aug 14, 2026 · 30d
26 quarters · since Mar 2020
Portfolio Concentration
83 tracked positions · as of Jun 30, 2026 · Δ vs Mar 31, 2026Top Position
24.2%
−1.5 pts
Top 5
47.4%
−1.3 pts
Top 10
61.3%
−1.2 pts
HHI
804
Diversified−67
Portfolio Trend
26 quarters · across all stocks
Sector Breakdown
As of Jun 30, 2026| Sector | % Portfolio | Value |
|---|---|---|
| Healthcare | 99.8% | $11,330,791,562 |
| Financial Services | 0.2% | $22,790,000 |
Last Quarter's Activity
Export CSVAdded To
Positions the filer increased
10 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| ARTV | Artiva Biotherapeutics, Inc. | +8,102,340 | 17,955,642 | $174,169,727 | |
| ACRS | Aclaris Therapeutics, Inc. | +5,918,954 | 12,723,026 | $67,304,807 | |
| ACRV | Acrivon Therapeutics, Inc. | +3,888,888 | 12,229,396 | $21,768,324 | |
| SLDB | Solid Biosciences Inc. | +2,696,148 | 12,036,126 | $120,240,898 | |
| XNCR | Xencor Inc | +377,037 | 5,274,274 | $84,915,811 | |
| AVTX | Avalo Therapeutics, Inc. | +337,032 | 1,000,000 | $18,480,000 | |
| RZLT | Rezolute, Inc. | +265,039 | 9,445,039 | $49,114,202 | |
| ZLAB | Zai Lab Ltd | +36,271 | 5,743,533 | $109,127,127 | |
| BIOA | BioAge Labs, Inc. | +21,000 | 1,671,648 | $40,972,092 | |
| DMRA | Damora Therapeutics, Inc. | +392 | 2,399,702 | $62,416,249 | |
| No positions match the current search. | |||||
Trimmed
Positions the filer reduced
10 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| GERN | Geron Corp | −20,961,615 | 42,809,751 | $54,796,481 | |
| HOWL | Werewolf Therapeutics, Inc. | −4,293,563 | 2,387,744 | $859,587 | |
| VOR | Vor Biopharma Inc. | −3,002,903 | 2,402,095 | $44,222,568 | |
| EWTX | Edgewise Therapeutics, Inc. | −2,035,707 | 8,392,730 | $340,996,619 | |
| — | −1,287,689 | 1,246,456 | $0 | ||
| ACET | Adicet Bio, Inc. | −250,000 | 932,624 | $8,057,871 | |
| OVID | Ovid Therapeutics Inc. | −213,032 | 10,500,968 | $28,247,603 | |
| AKTS | Aktis Oncology, Inc. | −188,679 | 1,314,405 | $42,363,273 | |
| GHRS | GH Research PLC | −39,884 | 7,636,813 | $205,277,533 | |
| PTN | Palatin Technologies Inc | −7,876 | 62,124 | $670,317 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
16 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| PBLS | Parabilis Medicines, Inc. | 28,933,371 | $791,906,364 | |
| COAG | Hemab Therapeutics Holdings, Inc. | 7,808,627 | $286,810,869 | |
| ABVX | Abivax S.A. | 1,132,557 | $150,924,545 | |
| ORKA | Oruka Therapeutics, Inc. | 1,554,597 | $147,950,996 | |
| NTLA | Intellia Therapeutics, Inc. | 4,526,926 | $76,595,587 | |
| DFTX | Definium Therapeutics, Inc. | 1,500,000 | $70,560,000 | |
| SANA | Sana Biotechnology, Inc. | 18,750,000 | $65,437,500 | |
| PRLD | Prelude Therapeutics Inc | 6,475,882 | $34,516,451 | |
| QTTB | Q32 Bio Inc. | 2,332,457 | $29,715,502 | |
| EDIT | Editas Medicine, Inc. | 8,889,000 | $28,800,360 | |
| ALT | Altimmune, Inc. | 6,500,000 | $19,760,000 | |
| FTH | Faeth Therapeutics, Inc. | 722,020 | $18,050,500 | |
| AURA | Aura Biosciences, Inc. | 2,500,000 | $17,750,000 | |
| SPTX | Seaport Therapeutics, Inc. | 700,000 | $15,204,000 | |
| JATT | JATT II Acquisition Corp. | 500,000 | $5,680,000 | |
| AMAN | Amanat Acquisition Corp. | 375,000 | $3,810,000 | |
| No positions match the current search. | ||||
Sold Out
Positions the filer fully exited
17 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| DNTH | Dianthus Therapeutics, Inc. /DE/ | 2,611,733 | $219,176,633 | |
| PRAX | Praxis Precision Medicines, Inc. | 373,787 | $120,430,433 | |
| SRPT | Sarepta Therapeutics, Inc. | 3,902,596 | $84,920,488 | |
| SYRE | Spyre Therapeutics, Inc. | 1,621,620 | $81,794,512 | |
| FULC | Fulcrum Therapeutics, Inc. | 6,053,960 | $46,433,873 | |
| OLMA | Olema Pharmaceuticals, Inc. | 2,600,000 | $38,766,000 | |
| DSGN | Design Therapeutics, Inc. | 2,972,973 | $31,632,432 | |
| TVTX | Travere Therapeutics, Inc. | 746,841 | $22,188,646 | |
| GRAL | GRAIL, Inc. | 428,266 | $22,132,786 | |
| RLMD | Relmada Therapeutics, Inc. | 2,947,369 | $20,513,688 | |
| STRO | Sutro Biopharma, Inc. | 715,307 | $17,818,297 | |
| CTNM | Contineum Therapeutics, Inc. | 1,296,012 | $16,925,916 | |
| INSP | Inspire Medical Systems, Inc. | 325,663 | $16,797,697 | |
| HNGE | Hinge Health, Inc. | 364,613 | $14,059,477 | |
| WGS | GeneDx Holdings Corp. | 209,887 | $13,478,943 | |
| RNA | Atrium Therapeutics, Inc. | 864,102 | $11,553,043 | |
| MPLT | MapLight Therapeutics, Inc. | 248,294 | $5,047,817 | |
| No positions match the current search. | ||||
83 tracked positions ·
$11,353,581,562 total
· filing declares
85 positions · $11,507,522,068
· as of Jun 30, 2026
Showing 1–50
of 83 positions by value
· page 1 of 2
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| ASND |
Ascendis Pharma A/S
Healthcare
|
Held | 10,281,496 | $2,742,280,613 | 24.15% | |
| PBLS |
Parabilis Medicines, Inc.
Healthcare
|
NEW | 28,933,371 | $791,906,364 | 6.97% | |
| RYTM |
Rhythm Pharmaceuticals, Inc.
Healthcare
|
Held | 6,666,837 | $740,218,912 | 6.52% | |
| PCVX |
Vaxcyte, Inc.
Healthcare
|
Held | 11,474,599 | $667,018,439 | 5.87% | |
| SION |
Sionna Therapeutics, Inc.
Healthcare
|
Held | 9,905,045 | $435,722,929 | 3.84% | |
| TYRA |
Tyra Biosciences, Inc.
Healthcare
|
Held | 12,198,625 | $389,624,082 | 3.43% | |
| EWTX |
Edgewise Therapeutics, Inc.
Healthcare
|
Reduced | 8,392,730 | $340,996,619 | 3.00% | |
| NAMS |
NewAmsterdam Pharma Co N.V.
Healthcare
|
Held | 9,883,524 | $330,779,298 | 2.91% | |
| COAG |
Hemab Therapeutics Holdings, Inc.
Healthcare
|
NEW | 7,808,627 | $286,810,869 | 2.53% | |
| SEPN |
Septerna, Inc.
Healthcare
|
Held | 6,995,858 | $234,291,284 | 2.06% | |
| BCAX |
Bicara Therapeutics Inc.
Healthcare
|
Held | 7,255,993 | $215,430,432 | 1.90% | |
| MLYS |
Mineralys Therapeutics, Inc.
Healthcare
|
Held | 7,692,750 | $207,550,395 | 1.83% | |
| GHRS |
GH Research PLC
Healthcare
|
Reduced | 7,636,813 | $205,277,533 | 1.81% | |
| IRON |
Disc Medicine, Inc.
Healthcare
|
Held | 2,450,221 | $179,209,163 | 1.58% | |
| SGP |
SpyGlass Pharma, Inc.
Healthcare
|
Held | 8,021,117 | $178,550,064 | 1.57% | |
| ARTV |
Artiva Biotherapeutics, Inc.
Healthcare
|
Added | 17,955,642 | $174,169,727 | 1.53% | |
| JANX |
Janux Therapeutics, Inc.
Healthcare
|
Held | 11,189,693 | $171,873,684 | 1.51% | |
| TSHA |
Taysha Gene Therapies, Inc.
Healthcare
|
Held | 23,555,648 | $160,413,962 | 1.41% | |
| BCRX |
Biocryst Pharmaceuticals Inc
Healthcare
|
Held | 15,827,186 | $158,271,860 | 1.39% | |
| WVE |
Wave Life Sciences, Inc.
Healthcare
|
Held | 26,975,505 | $156,727,684 | 1.38% | |
| ABVX |
Abivax S.A.
Healthcare
|
NEW | 1,132,557 | $150,924,545 | 1.33% | |
| ORKA |
Oruka Therapeutics, Inc.
Healthcare
|
NEW | 1,554,597 | $147,950,996 | 1.30% | |
| CLYM |
Climb Bio, Inc.
Healthcare
|
Held | 11,300,939 | $147,364,243 | 1.30% | |
| SLDB |
Solid Biosciences Inc.
Healthcare
|
Added | 12,036,126 | $120,240,898 | 1.06% | |
| ZLAB |
Zai Lab Ltd
Healthcare
|
Added | 5,743,533 | $109,127,127 | 0.96% | |
| SPRY |
ARS Pharmaceuticals, Inc.
Healthcare
|
Held | 10,860,977 | $86,996,425 | 0.77% | |
| XNCR |
Xencor Inc
Healthcare
|
Added | 5,274,274 | $84,915,811 | 0.75% | |
| JBIO |
Jade Biosciences, Inc.
Healthcare
|
Held | 3,671,083 | $81,571,464 | 0.72% | |
| NTLA |
Intellia Therapeutics, Inc.
Healthcare
|
NEW | 4,526,926 | $76,595,587 | 0.67% | |
| LBRX |
Lb Pharmaceuticals Inc
Healthcare
|
Held | 2,208,604 | $71,680,242 | 0.63% | |
| DFTX |
Definium Therapeutics, Inc.
Healthcare
|
NEW | 1,500,000 | $70,560,000 | 0.62% | |
| ACRS |
Aclaris Therapeutics, Inc.
Healthcare
|
Added | 12,723,026 | $67,304,807 | 0.59% | |
| FDMT |
4D Molecular Therapeutics, Inc.
Healthcare
|
Held | 5,049,779 | $67,162,060 | 0.59% | |
| SANA |
Sana Biotechnology, Inc.
Healthcare
|
NEW | 18,750,000 | $65,437,500 | 0.58% | |
| DMRA |
Damora Therapeutics, Inc.
Healthcare
|
Added | 2,399,702 | $62,416,249 | 0.55% | |
| MNPR |
Monopar Therapeutics
Healthcare
|
Held | 667,207 | $61,776,696 | 0.54% | |
| ABOS |
Acumen Pharmaceuticals, Inc.
Healthcare
|
Held | 20,992,669 | $56,050,426 | 0.49% | |
| GERN |
Geron Corp
Healthcare
|
Reduced | 42,809,751 | $54,796,481 | 0.48% | |
| RZLT |
Rezolute, Inc.
Healthcare
|
Added | 9,445,039 | $49,114,202 | 0.43% | |
| EVMN |
Evommune, Inc.
Healthcare
|
Held | 3,494,638 | $46,443,739 | 0.41% | |
| VOR |
Vor Biopharma Inc.
Healthcare
|
Reduced | 2,402,095 | $44,222,568 | 0.39% | |
| IPSC |
Century Therapeutics, Inc.
Healthcare
|
Held | 17,754,430 | $43,498,353 | 0.38% | |
| AKTS |
Aktis Oncology, Inc.
Healthcare
|
Reduced | 1,314,405 | $42,363,273 | 0.37% | |
| BIOA |
BioAge Labs, Inc.
Healthcare
|
Added | 1,671,648 | $40,972,092 | 0.36% | |
| CCCC |
C4 Therapeutics, Inc.
Healthcare
|
Held | 8,000,000 | $37,360,000 | 0.33% | |
| MIRM |
Mirum Pharmaceuticals, Inc.
Healthcare
|
Held | 318,554 | $37,293,116 | 0.33% | |
| CAPR |
Capricor Therapeutics, Inc.
Healthcare
|
Held | 1,507,844 | $36,308,883 | 0.32% | |
| PEPG |
PepGen Inc.
Healthcare
|
Held | 20,064,545 | $36,116,181 | 0.32% | |
| PRLD |
Prelude Therapeutics Inc
Healthcare
|
NEW | 6,475,882 | $34,516,451 | 0.30% | |
| NKTX |
Nkarta, Inc.
Healthcare
|
Held | 10,805,129 | $30,578,515 | 0.27% |
Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.