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Equibles

CCCC

C4 Therapeutics, Inc.
$4.30 -0.04 (-0.92%) At close · Jul 2
Market Cap
$475.44M
Shares
110,567,222

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Holders: 124
Total Value: $284,780,901
Total Shares: 108,281,737
Showing 1–100 of 130 holdings by value · page 1 of 2

Institutional Ownership Trend

22 quarters

Holder Concentration

Across 123 13F filers · Δ vs Dec 31, 2025
Top Holder
10.7%
Jun 2023 → Mar 2026 · range 9.0% – 21.0%
−1.1 pts
Top 5
41.4%
Jun 2023 → Mar 2026 · range 40.1% – 60.5%
−9.4 pts
Top 10
59.8%
Jun 2023 → Mar 2026 · range 58.2% – 77.1%
−12.2 pts
HHI
498
Jun 2023 → Mar 2026 · range 484 – 831
Broadly held−159

Quarterly Activity

vs Dec 31, 2025
New
35
Increased
41
Decreased
30
Sold Out
12
Unchanged
18
Holder count: +23
Institutional value: +86.4%
Shares held: +35.3%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Mega JPMORGAN CHASE & CO +3,217,109 3,223,054
Mega CITADEL ADVISORS LLC +2,090,007 2,588,615
Mega TWO SIGMA INVESTMENTS, LP +1,526,031 3,035,634
Mega GOLDMAN SACHS GROUP INC +1,298,358 2,387,378
Large ACADIAN ASSET MANAGEMENT LLC +1,233,741 1,890,914

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Large Point72 Asset Management, L.P. −9,270,232 169,096
Large WASATCH ADVISORS LP −1,383,157 2,961,761
Mid ORBIMED ADVISORS LLC −548,549 856,353
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP −486,743 1,394,440
Large Walleye Capital LLC −229,023 239,518

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
— Sirenia Capital Management LP 23,505,000 $61,818,150
Mega VANGUARD CAPITAL MANAGEMENT LLC 3,861,852 $10,156,670
Small Squadron Capital Management LLC 2,250,000 $5,917,500
Large CONGRESS ASSET MANAGEMENT CO 830,624 $2,184,541
Mega VANGUARD FIDUCIARY TRUST CO 484,131 $1,273,264

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mega VANGUARD GROUP INC 4,379,815 $8,365,446
Large TWO SIGMA ADVISERS, LP 1,068,200 $2,040,262
Mid ArrowMark Colorado Holdings LLC 204,505 $390,604
Mid SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 67,617 $129,148
Mid GROUP ONE TRADING LLC 38,994 $74,478
Filter: New 35 Increased 41 Reduced 30 Sold out 12 Unchanged 18
Showing 100 of 130
All Common Calls Puts
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Holder Value (USD) % of 13F Shares Open
— Sirenia Capital Management LP $61,818,150 21.71% 23,505,000
Mega MORGAN STANLEY $23,860,411 8.38% 9,072,400
Mid RA CAPITAL MANAGEMENT, L.P. $21,040,000 7.39% 8,000,000
Mid Bain Capital Life Sciences Investors, LLC $18,862,123 6.62% 7,171,910
Small Lynx1 Capital Management LP $18,407,112 6.46% 6,998,902
Mega VANGUARD CAPITAL MANAGEMENT LLC $10,156,670 3.57% 3,861,852
Mid Soleus Capital Management, L.P. $10,004,367 3.51% 3,803,942
Mega JPMORGAN CHASE & CO $8,476,631 2.98% 3,223,054
Mega TWO SIGMA INVESTMENTS, LP $7,983,717 2.80% 3,035,634
Large WASATCH ADVISORS LP $7,789,431 2.74% 2,961,761
Mega CITADEL ADVISORS LLC $6,603,969 2.32% 2,511,015
Large RENAISSANCE TECHNOLOGIES LLC $6,474,573 2.27% 2,461,815
Mega GOLDMAN SACHS GROUP INC $6,278,803 2.20% 2,387,378
Mega BANK OF AMERICA CORP /DE/ Bank $6,204,801 2.18% 2,359,241
Small Squadron Capital Management LLC $5,917,500 2.08% 2,250,000
Mega BlackRock, Inc. $5,387,621 1.89% 2,048,526
Small SILVERARC CAPITAL MANAGEMENT, LLC $5,027,994 1.77% 1,911,785
Large ACADIAN ASSET MANAGEMENT LLC $4,973,103 1.75% 1,890,914
Mega MILLENNIUM MANAGEMENT LLC $3,664,489 1.29% 1,393,342
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $3,384,389 1.19% 1,286,840
Mega JANE STREET GROUP, LLC $3,279,336 1.15% 1,246,896
Mega D. E. Shaw & Co., Inc. $2,788,670 0.98% 1,060,331
Mega GEODE CAPITAL MANAGEMENT, LLC $2,501,242 0.88% 951,043
Mega WELLS FARGO & COMPANY/MN $2,282,605 0.80% 867,911
Mid ORBIMED ADVISORS LLC $2,252,208 0.79% 856,353
Large CONGRESS ASSET MANAGEMENT CO $2,184,541 0.77% 830,624
Large Qube Research & Technologies Ltd $1,978,059 0.69% 752,114
Mega VANGUARD FIDUCIARY TRUST CO Bank $1,273,264 0.45% 484,131
Small STEMPOINT CAPITAL LP $1,192,010 0.42% 453,236
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $1,189,359 0.42% 452,228
Mega DIMENSIONAL FUND ADVISORS LP $1,163,821 0.41% 442,518
Small PLATINUM INVESTMENT MANAGEMENT LTD $1,011,934 0.36% 384,766
Mega STATE STREET CORP $1,007,218 0.35% 382,973
Mega BARCLAYS PLC $836,016 0.29% 317,877
Mid 683 Capital Management, LLC $789,000 0.28% 300,000
Large Connor, Clark & Lunn Investment Management Ltd. $728,991 0.26% 277,183
Mega FMR LLC $716,327 0.25% 272,368
Large JACOBS LEVY EQUITY MANAGEMENT, INC $695,950 0.24% 264,620
Mid Susquehanna Portfolio Strategies, LLC $684,533 0.24% 260,279
Large Man Group plc $674,510 0.24% 256,468
Mega LPL Financial LLC $649,084 0.23% 246,800
Mega Invesco Ltd. $643,053 0.23% 244,507
Large Walleye Capital LLC $628,880 0.22% 239,118
Mid Hennion & Walsh Asset Management, Inc. $586,931 0.21% 223,168
Mega UBS Group AG $567,756 0.20% 215,877
Mega BNP PARIBAS ARBITRAGE, SA $500,615 0.18% 190,348
Mega NORTHERN TRUST CORP Bank $498,329 0.17% 189,479
Large TORONTO DOMINION BANK Bank $459,363 0.16% 174,663
Large Point72 Asset Management, L.P. $444,722 0.16% 169,096
Large HRT FINANCIAL LP $428,505 0.15% 162,930
Large MARSHALL WACE, LLP $408,951 0.14% 155,495
Mid Atom Investors LP $357,803 0.13% 136,047
Mega CANADA PENSION PLAN INVESTMENT BOARD Pension $356,628 0.13% 135,600
Mid BRIDGEWAY CAPITAL MANAGEMENT, LLC $344,793 0.12% 131,100
Large Hudson Bay Capital Management LP $342,113 0.12% 130,081
Large Mariner, LLC $335,369 0.12% 127,517
Micro Verdad Advisers, LP $287,740 0.10% 109,407
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $282,988 0.10% 107,600
Mid Brevan Howard Capital Management LP $243,661 0.09% 92,647
Mega JANE STREET GROUP, LLC $228,284 0.08% 86,800
Large PANAGORA ASSET MANAGEMENT INC $228,178 0.08% 86,760
Small AXQ CAPITAL, LP $226,911 0.08% 86,278
Mega AMERICAN CENTURY COMPANIES INC $224,717 0.08% 85,444
Small Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group Insurance $223,550 0.08% 85,000
Mega PRICE T ROWE ASSOCIATES INC /MD/ $188,165 0.07% 71,546
Mid Crestwood Advisors Group, LLC $174,989 0.06% 66,536
Mid Quadrature Capital Ltd $165,058 0.06% 62,760
Large Jain Global LLC $164,085 0.06% 62,390
Micro INTREPID FAMILY OFFICE LLC Family Office $157,800 0.06% 60,000
Large OMERS ADMINISTRATION Corp $157,011 0.06% 59,700
Small Seven Fleet Capital Management LP $150,109 0.05% 57,076
Mid READYSTATE ASSET MANAGEMENT LP $130,411 0.05% 49,586
Large ExodusPoint Capital Management, LP $124,943 0.04% 47,507
Mid XTX Topco Ltd $124,007 0.04% 47,151
Mega CITADEL ADVISORS LLC $115,720 0.04% 44,000
Mid ADAR1 Capital Management, LLC $113,090 0.04% 43,000
Mega CITIGROUP INC $111,585 0.04% 42,428
Large Squarepoint Ops LLC $106,946 0.04% 40,664
Large Focus Partners Wealth $100,431 0.04% 38,187
Small Diametric Capital, LP $90,982 0.03% 34,594
Mega Vanguard Global Advisers, LLC $88,978 0.03% 33,832
Mega CITADEL ADVISORS LLC $88,368 0.03% 33,600
Mid PRELUDE CAPITAL MANAGEMENT, LLC $81,416 0.03% 30,957
Large FARALLON CAPITAL MANAGEMENT LLC $73,640 0.03% 28,000
Large Jefferies Financial Group Inc. $68,695 0.02% 26,120
Small Catalyst Funds Management Pty Ltd $67,696 0.02% 25,740
Large SEI INVESTMENTS CO $66,102 0.02% 25,134
Large Cresset Asset Management, LLC $65,750 0.02% 25,000
Mid WINTON GROUP Ltd $64,961 0.02% 24,700
Large Schonfeld Strategic Advisors LLC $62,972 0.02% 23,944
Mid Graham Capital Management, L.P. $62,417 0.02% 23,733
Large Corient Private Wealth LLC $56,247 0.02% 21,387
Mid Callan Family Office, LLC Family Office $50,353 0.02% 19,146
Mid China Universal Asset Management Co., Ltd. $45,541 0.02% 17,316
Large PRUDENTIAL FINANCIAL INC $41,948 0.01% 15,950
Mid Vanguard Personalized Indexing Management, LLC $40,104 0.01% 15,249
Micro Dauntless Investment Group, LLC $39,450 0.01% 15,000
Small EWA, LLC $38,324 0.01% 14,572
Mid NINE MASTS CAPITAL Ltd $37,232 0.01% 14,157
Mega HSBC HOLDINGS PLC $35,844 0.01% 13,629
Key facts CIK 1662579 CUSIP 12529R107 Visit website Investor relations

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