ADAGE CAPITAL PARTNERS GP, L.L.C.

Position in CCCC — C4 Therapeutics, Inc.

CIK 1165408 Boston, MA

Position in CCCC

as of Jun 30, 2026 · filed Aug 14, 2026 Compact

Position Value

$1,517,750

+$1,231,750 QoQ

Shares Held

325,000

+62.5% QoQ

Ownership

0.264%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

#47

of 147 holders

Holding Since

Dec 2020

10 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

ADAGE CAPITAL PARTNERS GP, L.L.C. holds $4,240,035,723 across 126 Biotechnology names. CCCC ranks #115 (0.0% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	ROIV	Roivant Sciences Ltd.	10,349,328	$366,262,717
2	PRAX	Praxis Precision Medicines, Inc.	1,015,480	$339,972,549
3	VRTX	Vertex Pharmaceuticals Inc / Ma	393,964	$195,693,737
4	TNGX	Tango Therapeutics, Inc.	5,600,000	$175,056,000
5	BBIO	BridgeBio Pharma, Inc.	2,252,000	$167,728,960
6	SYRE	Spyre Therapeutics, Inc.	1,722,300	$152,905,794
7	TVTX	Travere Therapeutics, Inc.	2,569,356	$145,965,114
8	RPRX	Royalty Pharma plc	2,500,000	$140,175,000

10 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$1,517,750	325,000	+62.5%	Shares	Sole	2026-08-14
2025-06-30	$286,000	200,000	-87.1%	Shares	Sole	2025-08-14
2025-03-31	$2,480,000	1,550,000	0.0%	Shares	Sole	2025-05-15
2024-12-31	$5,580,000	1,550,000	+198.1%	Shares	Sole	2025-02-14
2024-09-30	$2,964,000	520,000	-47.8%	Shares	Sole	2024-11-14
2021-12-31	$32,086,559	996,477	+22.8%	Shares	Sole	2022-02-14
2021-09-30	$36,256,792	811,477	+17.6%	Shares	Sole	2021-11-15
2021-06-30	$26,109,600	690,000	-21.6%	Shares	Sole	2021-08-16
2021-03-31	$32,569,621	880,498	-1.1%	Shares	Sole	2021-05-17
2020-12-31	$29,502,198	890,498	—	Shares	Sole	2021-02-16
No filing history on record for this holder in this stock.