C4 Therapeutics reported a 53% overall response rate at the highest simsidamide dose in 72 first-in-human patients. Enrollment is expected to finish in the first quarter of 2027, with combination data guided for mid-year 2027.
CCCC · C4 Therapeutics, Inc. · Documents
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C4 Therapeutics expects cash to fund operations to the end of 2028, while cemsidomide’s Phase 2 MOMENTUM enrollment is on track to complete in the first quarter of 2027; third-quarter 2026 revenue was $8.5 million.
C4 Therapeutics reported cemsidomide immune activation in 62 RRMM patients and biomarker findings from two patients; the 75 µg dose was declared safe, and cohorts at 75 µg and 100 µg are advancing, with data expected in mid-2027.