Skip to main content
SION logo

SION · Sionna Therapeutics, Inc. · Holdings

Track SION — free
$3.87 +0.18 (+4.88%) At close · Oct 27 Q2 2026 earnings call transcript
Market Cap
$165.93M
Shares
45.21M
Volume · Oct 27 1M Avg daily vol (3M) 2.25M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

The Sep 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out. Each fund's Change is measured against its own previous reported quarter, shown in the Reported column. Pick a completed quarter in the Quarter selector below to put every fund on one quarter and see the stock-wide activity breakdown.
Holders: 157
Total Value: $2,128,865,772
Total Shares: 49,351,885
Showing 1–100 of 161 holdings by value · page 1 of 2

Institutional Ownership Trend

7 quarters

Holder Concentration

Across 150 13F filers
Top Holder
20.5%
Mar 2025 → Jun 2026 · range 20.5% – 25.2%
of institutional value
Top 5
52.1%
Mar 2025 → Jun 2026 · range 52.1% – 66.2%
of institutional value
Top 10
69.1%
Mar 2025 → Jun 2026 · range 69.1% – 84.9%
of institutional value
HHI
806
Mar 2025 → Jun 2026 · range 806 – 1,200
Broadly held

Who Holds SION

Last 7 quarters through Sep 30, 2026 (filing window open)

Each kind of 13F filer's share of the common shares 13F filers report. Holder type comes from regulatory records, never the filer's name; style, turnover and horizon are measured from each filer's own 13F book. The quarter selector does not change this card.

Jun 30, 2026, the newest closed quarter: 146 filers, like-for-like change +5.9%; actively managed books +5.0%; index-like books +13.6%.

Holder type Share Filers Change
Registered adviser 56.6% 67 +5.0%
Exempt adviser 0.7% 3 +46.2%
Adviser 1.1% 4 -8.9%
Bank 6.3% 13 +16.6%
Benefit plan 0.0% 3 +525.5%
Non-US 0.3% 4 +2.2%
Holding company 5.4% 7 +9.9%
Insurer 0.0% 0 —
Unknown 29.5% 45 +4.7%

The Sep 30, 2026 filing window is still open, so its bar carries the Jun 30, 2026 positions of filers that have not filed yet.

How the mix is measured

Shares are 13F common shares restated to today's split basis; options and principal amounts are left out. The change compares only filers with a 13F in both quarters and keeps each filer in its bucket of the later quarter on both sides; a filer that continues under a new CIK is compared through its successor. Holder type comes from each filer's current regulatory profile; client base and private funds come from the Form ADV roster current at each quarter end (rosters from December 2019, so an earlier quarter reads Unknown). Style, turnover, horizon and book size are measured from each filer's 13F book in the newest measured quarter, and Not measured means none was. Actively managed books are those measured systematic-like, concentrated or diversified active.

Excluded 1 holder with no observed 2026-06-30 13F. Compared across CIK changes: JANUS HENDERSON GROUP PLC continues as Jupiter Topco LLC.

Conviction and Crowding

146 13F filers, quarter ended Jun 30, 2026

Measured across every 13F filer's common-share book once the quarter's filing window closed. Crowding counts filers with high turnover or that advise private funds on Form ADV.

Conviction holders
7
4.79% of filers hold it in their top 10
Mar 31, 2026: 8
Holders above 5%
4
median weight 0.002%
Mar 31, 2026: 4
Crowding
—
holders exceed shares outstanding: 13F filers report more shares than the cover-page count, which predates an issuance, is misstated, or misses shares lent and reported twice
Private-fund advisers
—
of shares outstanding
Institutional ownership
—
holders exceed shares outstanding: 13F filers report more shares than the cover-page count, which predates an issuance, is misstated, or misses shares lent and reported twice
Top 10 holders
69.4%
of 13F shares, Herfindahl 0.081
Active holders
+5.0%
like-for-like share change of active filers
5% stakes on record
6
5 13D, 1 13G (0 institutional, 1 passive, 0 exempt)
How long holders have held it value-weighted 5.4 quarters
Under 1 year 14.0% 1 to 3 years 86.0% 3 years or more 0.000% Since coverage start 0.000%

Managers in the top fifth by current three-year FundScore alpha were net buyers of $0 (0 buying, 0 selling).

Estimated Holder Cost Basis

Quarter ended Jun 30, 2026, on that quarter's share basis

Estimated, never filed: each 13F buy is costed at its quarter's average traded price and each sale keeps the average cost, so this is what holders paid on average if they traded evenly through each quarter.

Estimated avg cost
$21.81
estimated per share
Mar 31, 2026: $19.58
Quarter-end price
$43.99
implied by 13F values
Estimated gain or loss
+101.7%
price against the estimated cost
Estimated at a loss
0.000%
of costed 13F value

Estimated cost covers 96.5% of the 13F shares; positions already held when a filer's 13F history starts, or bought in a quarter without a trusted average price, have no estimate.

Shared Holders

Companies SION's active holders also own, quarter ended Jun 30, 2026
# Company Shared holders
1 TYRA Tyra Biosciences, Inc. 8
2 RAPP Rapport Therapeutics, Inc. 7
3 AVLN Avalyn Pharma Inc. 8
4 PRAX Praxis Precision Medicines, Inc. 12
5 XENE Xenon Pharmaceuticals Inc. 12
6 ELVN Enliven Therapeutics, Inc. 11
7 MNPR Monopar Therapeutics 6
8 ERAS Erasca, Inc. 10
9 IRON Disc Medicine, Inc. 9
10 SYRE Spyre Therapeutics, Inc. 11

Shareholder Targets

13F filers that own its peers but not SION, quarter ended Jun 30, 2026

Found through its holder-overlap peers: TYRA, RAPP, AVLN, PRAX, XENE, ELVN, MNPR, ERAS, IRON, SYRE, TARA, EWTX, RYTM, ORKA, ORIC, PBLS, MOBI, PRLD, SEPN, SRRK. 600 filers in all.

# Filer In peers
1 Polar Capital Holdings Plc Registered adviser, Diversified active $1,275,245,383 9 held
2 Paradigm Biocapital Advisors LP Registered adviser, Concentrated $1,193,494,452 5 held
3 Venrock Adviser, LLC Registered adviser, Concentrated $1,078,232,562 6 held
4 RTW INVESTMENTS, LP Registered adviser, Diversified active $1,007,212,422 4 held
5 Orbis Allan Gray Ltd Unknown, Diversified active $838,502,039 2 held
6 T. Rowe Price Investment Management, Inc. Adviser, Diversified active $762,206,661 7 held
7 Cormorant Asset Management, LP Registered adviser, Diversified active $741,581,067 8 held
8 Capital World Investors Adviser, Diversified active $705,691,820 7 held
9 Frazier Life Sciences Management, L.P. Registered adviser, Concentrated $609,211,751 3 held
10 Pictet Asset Management Holding SA Unknown, Diversified active $535,304,723 11 held

Fund Ownership of SION by Fund Type

Registered funds' Form N-PORT reports for the quarter ended Jun 30, 2026

Index funds and index ETFs hold 7.74% of shares outstanding.

Fund type Of shares outstanding Shares
Index funds 1.30% 589,199
Index ETFs 6.44% 2,910,114
Active ETFs 0.13% 58,706
Active funds 6.43% 2,905,702
Unclassified 0.24% 106,290
All registered funds 14.53% 6,570,011
How fund types are measured

Each fund series counts once, with its latest Form N-PORT report dated inside the quarter; only long share positions count, restated to today's split basis. The fund type is the series' latest Form N-CEN answer on or before the quarter end (the index-fund box and the exchange-traded flag), never its name. Unclassified funds have no usable N-CEN; unit investment trusts are among them, so index ownership is a floor. Funds sit inside their advisers' 13F reports, so these shares overlap the 13F figures and are never added to them.

Showing 100 of 161
Export CSV
Holder Value (USD) % of 13F Shares Open

Showing the top 100 of 161 holders. Create a free account to see every holder, past quarters, search, filters and CSV export.

Key facts CIK 2036042 CUSIP 829401108 13F (30d) 16 filings 16 filers Visit website Investor relations