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SION · Sionna Therapeutics, Inc.

$45.85 -0.70 (-1.50%)
Market Cap
$2.10B
Shares
45.15M

Price & Indicators

20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$46.55 Open$45.41 Day$44.11–46.69 52W$16.38–51.29 Avg vol 30d537K Short int5.3M · 11.6% float · 11.5d Short vol62% Last earningsMay 12, 2026 DataFeb 2025–Jul 2026 Filing10-Q · May 12

Up next

Next earnings call
Jul 30, 2026 Est · unconfirmed · this week
FQ3-26 quarter ends
~Sep 30, 2026 Est
filed May 12, 2026

Equibles Rating

blended score · not investment advice
Overall
Neutral
SellHoldBuy
Technical Buy Momentum Strong Sentiment Bullish Fundamentals Strong Quant / Vol Very High
Market backdrop VIX 18.2 · elevated Equity put/call 0.71
Technical
price trend
Buy
50 / 200-day cross No cross
Price vs 200-day avg +18%
above
Price vs 50-day avg +13%
above
RSI (14) 57
neutral
MACD trend Negative
52-week position 86%
near high
Volume (OBV) Confirms
volume backs price
Momentum
relative strength
Strong
1-month return +10%
trailing
6-month return +5%
trailing
YTD return +13%
this year
Relative strength −3%
vs S&P · 6-mo
Sentiment
smart money
Bullish
Trend (MA cross) No cross
50d $41 › 200d $40 — 50d above 200d
Institutional flow Accumulating
14 of 121 funds reported for Jun 30 · net +198 sh shares · +3 new
Insider flow Distributing
Net -$26.7M over 90 days · 100% sells
Short interest Falling
11.64% of float · ▼ -4.8% MoM · 11.5 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
121 holders — near 1-yr high, broad support
Squeeze score 77
high risk · 0–100
Fundamentals
Strong
EPS growth +88%
Y/Y
Free cash flow $-66.7M
Balance sheet $58.5M
net cash
Quant / Vol
risk profile
Very High
Volatility 78%
annualized · 1-yr
Max drawdown −27%
past year
ATR 7.1%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Technicals

trend & momentum for long-term holders Buy
1 · 3 · 3
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
+18% Bullish
Price vs 50-day avg
+13% Bullish
RSI (14)
57 Neutral
MACD trend
Negative Bearish
52-week position
86% Bullish
Volume (OBV)
Confirms Neutral
Market signals — smart money & positioning
Bullish · 3 of 6
Trend (MA cross) No cross
50d $41 › 200d $40 — 50d above 200d
Institutional flow Accumulating
14 of 121 funds reported for Jun 30 · net +198 sh shares · +3 new
Insider flow Distributing
Net -$26.7M over 90 days · 100% sells
Short interest Falling
11.64% of float · ▼ -4.8% MoM · 11.5 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
121 holders — near 1-yr high, broad support
Price context
position in its 52-week range
52-wk low $16 Now $47 · 86% 52-wk high $51
vs 200-day avg +18% vs 50-day avg +13%

Illustrative technical + ownership context — a signal mix, not investment advice.

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
SION
Sionna Therapeutics, Inc.
this stock
$2.10B +13.2% 11.6%
ONC
BeOne Medicines Ltd.
$473.24B +7.3% +22179.2% 963.1 0.1%
VRTX
Vertex Pharmaceuticals Inc / Ma
$124.46B +8.2% +46.2% 29.1 2.0%
REGN
Regeneron Pharmaceuticals, Inc.
$72.88B -9.8% +20.8% 17.0 3.3%
ARGX
Argenx SE
$54.57B +3.7% 2.5%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Accumulating
Holders
123
% held
100.3%
Reported
14 of 121
Top holder
RA CAPITAL MANAGEMENT, L.…
Held Float
View
Held by Funds
Fund positions
133
View
Short & Settlement
Short Interest Falling
Shares short
5.3M
Days to cover
11.5d
Change
-265.0K sh
View
Short Volume
Short vol %
62%
As of
Jul 28, 2026
Short Total
View
Fails to Deliver
FTD shares
9.7K
Value
$416.0K
As of
Jun 30, 2026
View
Off-Exchange
Off-exchange %
50.9%
Week of
May 4, 2026
Off-exch Lit
View
Smart Money
Insider Trades Net selling
Net (90d)
-$26.7M
Buyers / Sellers
0 / 2
Buyers Sellers
View
Financials
Financials
Net income (FY)
$-75.3M
EPS diluted
$-1.88
View
Filings
SEC Filings
Latest
Investor Event Transcript
Filed
Jun 30, 2026
This year
8
View
Proposed Sales
Value
$450.9K
Shares
10.3K
Filed
Jul 6, 2026
View
Earnings & Events
Earnings Calls
Last call
Jun 10, 2026
View

Performance

5D 20D 120D MTD YTD
SION -1.4% +9.7% +4.7% +5.8% +13.2%
SPY -1.0% 0.0% +7.4% -0.8% +8.6%
vs SPY -0.4% +9.7% -2.8% +6.6% +4.5%
Key facts CIK 2036042 CUSIP 829401108 13F (30d) 13 filings 13 filers Visit website Investor relations