GHRS · GH Research PLC · Holdings

$21.11 +0.66 (+3.23%) At close · Oct 9

Market Cap

$1.45B

68.64M

Volume · Oct 9 146.04K Avg daily vol (3M) 292.08K

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Use institutional holdings through the 13F API or MCP →

Some SEC filings for this period have not finished importing. Holder totals and changes may be incomplete; these filings remain queued for recovery.

The Sep 30, 2026 filing window is still open — showing the latest known positions. Funds that have not filed yet carry their prior-quarter positions; a fund that filed without this stock counts as sold out. Each fund's Change is measured against its own previous reported quarter, shown in the Reported column. Pick a completed quarter in the Quarter selector below to put every fund on one quarter and see the stock-wide activity breakdown.

Quarter:

Holders: 64

Total Value: $1,386,584,579

Total Shares: 51,585,491

Institutional Ownership Trend

22 quarters

Holder Concentration

Across 64 13F filers

Top Holder

25.7%

of institutional value

Top 5

80.4%

of institutional value

Top 10

94.5%

of institutional value

HHI

1,491

Broadly held

Showing 67 of 67

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

Lynx1 Capital Management LP

$356,517,181

25.71%

13,263,288

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Lynx1 Capital Advisors LLC	13,263,288	$356,517,181	100.0%	Other

BVF INC/IL

$232,516,247

16.77%

8,650,158

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BVF PARTNERS L P/IL	8,650,158	$232,516,247	100.0%	Defined

RA CAPITAL MANAGEMENT, L.P.

$205,277,533

14.80%

7,636,813

FMR LLC

$160,662,969

11.59%

5,977,045

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	3,024,749	$81,305,253	50.6%	Defined
FIDELITY MANAGEMENT TRUST CO	2,952,296	$79,357,716	49.4%	Defined

RTW INVESTMENTS, LP

$159,500,947

11.50%

5,933,815

Deep Track Capital, LP

$89,600,017

6.46%

3,333,334

Avoro Capital Advisors LLC

$48,384,000

3.49%

1,800,000

Foresite Capital Management VI LLC

$25,280,451

1.82%

940,493

Jefferies Financial Group Inc.

$19,146,624

1.38%

712,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jefferies Financial Services, Inc.	712,300	$19,146,624	100.0%	Defined

BlackRock, Inc.

$12,910,112

0.93%

480,287

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	24,419	$656,382	5.1%	Sole
BlackRock Fund Advisors	402,427	$10,817,237	83.8%	Sole
BlackRock Institutional Trust Company, N.A.	1,287	$34,594	0.3%	Sole
BlackRock Asset Management Ireland Ltd	52,154	$1,401,899	10.9%	Sole

UBS Group AG

$12,832,727

0.93%

477,408

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS AG	477,408	$12,832,727	100.0%	Defined

MILLENNIUM MANAGEMENT LLC

$8,692,965

0.63%

323,399

BRAIDWELL LP

$5,570,611

0.40%

207,240

BOOTHBAY FUND MANAGEMENT, LLC

$5,432,528

0.39%

202,103

JANE STREET GROUP, LLC

$4,568,282

0.33%

169,951

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	93,787	$2,520,994	55.2%	Defined
Jane Street Global Trading, LLC	76,164	$2,047,288	44.8%	Defined

HighVista Strategies LLC

$4,267,737

0.31%

158,770

Trexquant Investment LP

$4,133,256

0.30%

153,767

GOLDMAN SACHS GROUP INC

$3,996,330

0.29%

148,673

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	148,673	$3,996,330	100.0%	Defined

XTX Topco Ltd

$2,338,183

0.17%

86,986

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	86,986	$2,338,183	100.0%	Defined

CITADEL ADVISORS LLC

$2,310,389

0.17%

85,952

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	79,729	$2,143,115	92.8%	Defined
Held directly	6,223	$167,274	7.2%	Defined

AdvisorShares Investments LLC

$1,915,656

0.14%

71,267

CenterBook Partners LP

$1,866,439

0.13%

69,436

HRT FINANCIAL LP

$1,757,280

0.13%

65,375

MORGAN STANLEY

$1,403,618

0.10%

52,218

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO. LLC	8,236	$221,383	15.8%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	36,552	$982,517	70.0%	Defined
MORGAN STANLEY SMITH BARNEY LLC	4,725	$127,008	9.0%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	2,705	$72,710	5.2%	Defined

Point72 Asset Management, L.P.

$1,367,708

0.10%

50,882

MARSHALL WACE, LLP

$1,255,214

0.09%

46,697

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	46,697	$1,255,214	100.0%	Other

Qube Research & Technologies Ltd

$1,181,322

0.09%

43,948

GEODE CAPITAL MANAGEMENT, LLC

$1,088,183

0.08%

40,483

Axxion S.A.

$972,249

0.07%

36,170

TUDOR INVESTMENT CORP ET AL

$921,392

0.07%

34,278

NORTHERN TRUST CORP

$855,966

0.06%

31,844

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	20,286	$545,287	63.7%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	11,558	$310,679	36.3%	Defined

JANE STREET GROUP, LLC

$787,584

0.06%

29,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	29,300	$787,584	100.0%	Defined

D. E. Shaw & Co., Inc.

$681,273

0.05%

25,345

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	25,345	$681,273	100.0%	Defined

Quadrature Capital Ltd

$567,624

0.04%

21,117

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Quadrature US Inc.	21,117	$567,624	100.0%	Other

CITADEL ADVISORS LLC

$532,224

0.04%

19,800

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	19,800	$532,224	100.0%	Defined

JPMORGAN CHASE & CO

$504,752

0.04%

18,778

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
J.P. Morgan Securities LLC	13,575	$364,896	72.3%	Defined
J.P. Morgan Securities plc	5,203	$139,856	27.7%	Defined

Squarepoint Ops LLC

$495,398

0.04%

18,430

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	18,430	$495,398	100.0%	Defined

Virtus Investment Advisers, LLC

$416,424

0.03%

15,492

LETKO, BROSSEAU & ASSOCIATES INC

$414,624

0.03%

15,425

China Universal Asset Management Co., Ltd.

$360,702

0.03%

13,419

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$360,192

0.03%

13,400

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	13,400	$360,192	100.0%	Other

JANE STREET GROUP, LLC

$360,192

0.03%

13,400

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	13,400	$360,192	100.0%	Defined

HighTower Advisors, LLC

$341,376

0.02%

12,700

STATE STREET CORP

$300,061

0.02%

11,163

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SSGA FUNDS MANAGEMENT, INC.	11,163	$300,061	100.0%	Defined

Lion Point Capital, LP

$274,176

0.02%

10,200

Eversept Partners, LP

$233,103

0.02%

8,672

Farther Finance Advisors, LLC

$230,573

0.02%

9,820

HSBC HOLDINGS PLC

$210,927

0.02%

7,847

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
HSBC BANK PLC	7,847	$210,927	100.0%	Defined

BARCLAYS PLC

$160,661

0.01%

5,977

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS BANK PLC	5,977	$160,661	100.0%	Defined

ROYAL BANK OF CANADA

$157,973

0.01%

5,877

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC Capital Markets, LLC	5,800	$155,904	98.7%	Defined
Held directly	77	$2,069	1.3%	Sole

OSAIC HOLDINGS, INC.

$155,232

0.01%

5,775

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
OSAIC WEALTH, INC.	5,775	$155,232	100.0%	Defined

SIMPLEX TRADING, LLC

$127,384

0.01%

4,739

Mirae Asset Global Investments Co., Ltd.

$82,467

0.01%

3,068

North Star Investment Management Corp.

$59,136

0.00%

2,200

BNP PARIBAS ARBITRAGE, SA

$45,615

0.00%

1,697

CITIGROUP INC

$43,384

0.00%

1,614

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citigroup Financial Products Inc. joint	1,614	$43,384	100.0%	Defined

GF FUND MANAGEMENT CO. LTD.

$35,347

0.00%

1,315

WELLS FARGO & COMPANY/MN

$33,600

0.00%

1,250

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO CLEARING SERVICES, LLC	1,250	$33,600	100.0%	Defined

HARBOUR INVESTMENTS, INC.

$21,504

0.00%

800

JONES FINANCIAL COMPANIES LLLP

$20,832

0.00%

775

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Edward D. Jones & Co., L.P.	775	$20,832	100.0%	Sole

Tower Research Capital LLC (TRC)

$13,843

0.00%

515

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Latour Trading LLC (Latour)	515	$13,843	100.0%	Defined

SBI Securities Co., Ltd.

$11,047

0.00%

411

Ancora Advisors LLC

$7,633

0.00%

284

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ANCORA PRIVATE WEALTH ADVISORS, LLC	284	$7,633	100.0%	Sole

HOLLENCREST CAPITAL MANAGEMENT

$6,720

0.00%

250

Federation des caisses Desjardins du Quebec

$5,510

0.00%

205

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Desjardins Securities inc.	205	$5,510	100.0%	Defined

Cornerstone Financial Management LLC

$860

0.00%

Caitong International Asset Management Co., Ltd

$510

0.00%

Key facts CIK 1855129 CUSIP G3855L106 13F (30d) 2 filings 2 filers Visit website Investor relations