SPHERA FUNDS MANAGEMENT LTD.
Position in GPCR — Structure Therapeutics Inc.
CIK 1496201
TEL AVIV, L3
Position in GPCR
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$2,448,560
-$402,990 QoQ
Shares Held
50,800
+23.9% QoQ
Ownership
0.024%
of shares outstanding
% of Portfolio
0.43%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2025
5 quarters on record
Voting authority
Sole 100%
Shared 0%
None 0%
Common Shares in GPCR Over Time
Shares Held
Position Value (USD)
Derivatives in GPCR
reported options exposure · as of Sep 30, 2025CallValue
$1,400,000
CallShares
50,000
PutValue
$0
PutShares
0
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Mar 31, 2026SPHERA FUNDS MANAGEMENT LTD. holds $325,221,568 across 61 Biotechnology names. GPCR ranks #44 (0.8% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | MLYS |
Mineralys Therapeutics, Inc.
|
1,339,971 | $36,299,814 | |
| 2 | BBIO |
BridgeBio Pharma, Inc.
|
245,246 | $18,211,967 | |
| 3 | RARE |
Ultragenyx Pharmaceutical Inc.
|
809,333 | $16,955,526 | |
| 4 | SNDX |
Syndax Pharmaceuticals Inc
|
724,563 | $16,925,791 | |
| 5 | COGT |
Cogent Biosciences, Inc.
|
416,340 | $16,024,926 | |
| 6 | FOLD |
AMICUS THERAPEUTICS, INC.
|
603,377 | $8,724,831 | |
| 7 | APLS |
Apellis Pharmaceuticals, Inc.
|
214,914 | $8,645,990 | |
| 8 | BMRN |
Biomarin Pharmaceutical Inc
|
139,900 | $7,902,951 |
All Filings in GPCR
Export CSV
6 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $2,448,560 | 50,800 | Shares | Defined | 2026-05-15 | |
| 2025-12-31 | $2,851,550 | 41,000 | Shares | Defined | 2026-02-17 | |
| 2025-09-30 | $4,870,068 | 173,931 | Shares | Defined | 2025-11-14 | |
| 2025-09-30 | $1,400,000 | 50,000 | Call | Defined | 2025-11-14 | |
| 2025-06-30 | $1,989,608 | 95,931 | Shares | Defined | 2025-08-14 | |
| 2025-03-31 | $1,454,040 | 84,000 | Shares | Defined | 2025-05-15 | |
| No filing history on record for this holder in this stock. | ||||||