IOVA · Iovance Biotherapeutics, Inc.

Represents shares withheld by the Issuer to satisfy the mandatory tax withholding requirements upon vesting of the RSUs. This is not an open market sale of securities.

Represents the common stock remaining after deducting the common stock withheld for taxes.

Represents such shares underlying the restricted stock units ("RSUs") which vested on the transaction date.

Each RSU represents a contingent right to receive one share of the Issuer's common stock.

The remaining RSUs will vest in equal quarterly installments.

Such aggregate number reflects the remainder of such RSUs granted on February 10, 2025, but does not include any other RSUs held by such Reporting Person.

Represents shares withheld by the Issuer to satisfy the mandatory tax withholding requirements upon vesting of the RSUs. This is not an open market sale of securities.

Represents the common stock remaining after deducting the common stock withheld for taxes.

Each RSU represents a contingent right to receive one share of the Issuer's common stock.

The remaining RSUs will vest in equal quarterly installments.

Such aggregate number reflects the remainder of such RSUs granted on August 6, 2025, but does not include any other RSUs held by such Reporting Person.

Represents such shares underlying the restricted stock units ("RSUs") which vested on the transaction date.

Each deferred restricted stock unit ("DRSU") represents a contingent right to receive one share of the Issuer's common stock and are granted pursuant to the Issuer's 2018 Equity Incentive Plan (as amended).

Provided the Reporting Person continues to be providing service to the Issuer on the following dates, the DRSUs shall vest on the earlier of: (i) the first anniversary of the Transaction Date; or (ii) the day prior to the Issuer's next annual shareholder meeting. Notwithstanding the vesting, the issuance of the common stock will be deferred until the earlier of (i) three months after the Reporting Person's resignation or removal from the Board of Directors or no longer providing service because of death or disability, (ii) a change in control (as defined in the DRSU agreement) or (iii) ten years from the Transaction Date.

Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock.

Provided the Reporting Person is still employed with the Issuer on the following dates, the RSUs shall vest over three years, with (i) one-third of the RSUs vesting on the one-year anniversary of the date of grant and (ii) the remaining RSUs shall vest in eight equal quarterly installments over the next two years, commencing with the first quarter following the first anniversary of the date of grant.

Each deferred restricted stock unit ("DRSU") represents a contingent right to receive one share of the Issuer's common stock and are granted pursuant to the Issuer's 2018 Equity Incentive Plan (as amended).

Provided the Reporting Person continues to be providing service to the Issuer on the following dates, the DRSUs shall vest on the earlier of: (i) the first anniversary of the Transaction Date; or (ii) the day prior to the Issuer's next annual shareholder meeting. Notwithstanding the vesting, the issuance of the common stock will be deferred until the earlier of (i) three months after the Reporting Person's resignation or removal from the Board of Directors or no longer providing service because of death or disability, (ii) a change in control (as defined in the DRSU agreement) or (iii) ten years from the Transaction Date.

Each deferred restricted stock unit ("DRSU") represents a contingent right to receive one share of the Issuer's common stock and are granted pursuant to the Issuer's 2018 Equity Incentive Plan (as amended).

Provided the Reporting Person continues to be providing service to the Issuer on the following dates, the DRSUs shall vest on the earlier of: (i) the first anniversary of the Transaction Date; or (ii) the day prior to the Issuer's next annual shareholder meeting. Notwithstanding the vesting, the issuance of the common stock will be deferred until the earlier of (i) three months after the Reporting Person's resignation or removal from the Board of Directors or no longer providing service because of death or disability, (ii) a change in control (as defined in the DRSU agreement) or (iii) ten years from the Transaction Date.

Each deferred restricted stock unit ("DRSU") represents a contingent right to receive one share of the Issuer's common stock and are granted pursuant to the Issuer's 2018 Equity Incentive Plan (as amended).

Provided the Reporting Person continues to be providing service to the Issuer on the following dates, the DRSUs shall vest on the earlier of: (i) the first anniversary of the Transaction Date; or (ii) the day prior to the Issuer's next annual shareholder meeting. Notwithstanding the vesting, the issuance of the common stock will be deferred until the earlier of (i) three months after the Reporting Person's resignation or removal from the Board of Directors or no longer providing service because of death or disability, (ii) a change in control (as defined in the DRSU agreement) or (iii) ten years from the Transaction Date.

Each RSU represents a contingent right to receive one share of the Issuer's common stock.

The remaining RSUs will vest in equal quarterly installments.

Such aggregate number reflects the remainder of such RSUs granted on March 5, 2025, but does not include any other RSUs held by such Reporting Person.

Each RSU represents a contingent right to receive one share of the Issuer's common stock.

The remaining RSUs will vest in equal quarterly installments.

Such aggregate number reflects the remainder of such RSUs granted on March 5, 2025, but does not include any other RSUs held by such Reporting Person.

Each RSU represents a contingent right to receive one share of the Issuer's common stock.

The remaining RSUs will vest in equal quarterly installments.

Such aggregate number reflects the remainder of such RSUs granted on March 5, 2025, but does not include any other RSUs held by such Reporting Person.

Represents shares withheld by the Issuer to satisfy the mandatory tax withholding requirements upon vesting of the RSUs. This is not an open market sale of securities.

Represents the common stock remaining after deducting the common stock withheld for taxes.

Represents such shares underlying the restricted stock units ("RSUs") which vested on the transaction date.

Represents shares withheld by the Issuer to satisfy the mandatory tax withholding requirements upon vesting of the RSUs. This is not an open market sale of securities.

Represents common stock remaining after deducting the common stock withheld for taxes.

Each RSU represents a contingent right to receive one share of the Issuer's common stock.

The remaining RSUs will vest in equal quarterly installments.

Such aggregate number reflects the remainder of such RSUs granted on March 5, 2025, but does not include any other RSUs held by such Reporting Person.

Represents such shares underlying the restricted stock units ("RSUs") which vested on the transaction date.

Represents shares withheld by the Issuer to satisfy the mandatory tax withholding requirements upon vesting of the RSUs. This is not an open market sale of securities.

Represents the common stock remaining after deducting the common stock withheld for taxes.

Represents such shares underlying the restricted stock units ("RSUs") which vested on the transaction date.

Represents shares withheld by the Issuer to satisfy the mandatory tax withholding requirements upon vesting of the RSUs. This is not an open market sale of securities.

Represents common stock remaining after deducting the common stock withheld for taxes.

Represents such shares underlying the restricted stock units ("RSUs") which vested on the transaction date.

Represents such shares underlying the restricted stock units ("RSUs") which vested on the transaction date.

Each RSU represents a contingent right to receive one share of the Issuer's common stock.

The remaining RSUs will vest in equal quarterly installments.

Such aggregate number reflects the remainder of such RSUs granted on March 1, 2024, but does not include any other RSUs held by such Reporting Person.

Represents shares withheld by the Issuer to satisfy the mandatory tax withholding requirements upon vesting of the RSUs. This is not an open market sale of securities.

Represents the common stock remaining after deducting the common stock withheld for taxes.

Each RSU represents a contingent right to receive one share of the Issuer's common stock.

The remaining RSUs will vest in equal quarterly installments.

Such aggregate number reflects the remainder of such RSUs granted on March 1, 2024, but does not include any other RSUs held by such Reporting Person.

Each RSU represents a contingent right to receive one share of the Issuer's common stock.

The remaining RSUs will vest in equal quarterly installments.

Such aggregate number reflects the remainder of such RSUs granted on March 1, 2024, but does not include any other RSUs held by such Reporting Person.

Represents shares withheld by the Issuer to satisfy the mandatory tax withholding requirements upon vesting of the RSUs. This is not an open market sale of securities.

Represents common stock remaining after deducting the common stock withheld for taxes.

Represents such shares underlying the restricted stock units ("RSUs") which vested on the transaction date.

Represents such shares underlying the restricted stock units ("RSUs") which vested on the transaction date.

Represents such shares underlying the restricted stock units ("RSUs") which vested on the transaction date.

Represents shares withheld by the Issuer to satisfy the mandatory tax withholding requirements upon vesting of the RSUs. This is not an open market sale of securities.

Represents the common stock remaining after deducting the common stock withheld for taxes.

Represents shares withheld by the Issuer to satisfy the mandatory tax withholding requirements upon vesting of the RSUs. This is not an open market sale of securities.

Represents common stock remaining after deducting the common stock withheld for taxes.

Each RSU represents a contingent right to receive one share of the Issuer's common stock.

The remaining RSUs will vest in equal quarterly installments.

Such aggregate number reflects the remainder of such RSUs granted on March 1, 2024, but does not include any other RSUs held by such Reporting Person.

Represents such shares underlying the restricted stock units ("RSUs") which vested on the transaction date.

Each RSU represents a contingent right to receive one share of the Issuer's common stock.

The remaining RSUs will vest in equal quarterly installments.

Such aggregate number reflects the remainder of such RSUs granted on February 10, 2025, but does not include any other RSUs held by such Reporting Person.

Represents shares withheld by the Issuer to satisfy the mandatory tax withholding requirements upon vesting of the RSUs. This is not an open market sale of securities.

Represents the common stock remaining after deducting the common stock withheld for taxes.

Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock.

Provided the Reporting Person is still employed with the Issuer on the following dates, the RSUs shall vest over three years, with (i) one-third of the RSUs vesting on the one-year anniversary of the date of grant and (ii) the remaining RSUs shall vest in eight equal quarterly installments over the next two years, commencing with the first quarter following the first anniversary of the date of grant.

Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock.

Provided the Reporting Person is still employed with the Issuer on the following dates, the RSUs shall vest over three years, with (i) one-third of the RSUs vesting on the one-year anniversary of the date of grant and (ii) the remaining RSUs shall vest in eight equal quarterly installments over the next two years, commencing with the first quarter following the first anniversary of the date of grant.

Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock.

Provided the Reporting Person is still employed with the Issuer on the following dates, the RSUs shall vest over three years, with (i) one-third of the RSUs vesting on the one-year anniversary of the date of grant and (ii) the remaining RSUs shall vest in eight equal quarterly installments over the next two years, commencing with the first quarter following the first anniversary of the date of grant.

Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock.

Provided the Reporting Person is still employed with the Issuer on the following dates, the RSUs shall vest over three years, with (i) one-third of the RSUs vesting on the one-year anniversary of the date of grant and (ii) the remaining RSUs shall vest in eight equal quarterly installments over the next two years, commencing with the first quarter following the first anniversary of the date of grant.

Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock.

Provided the Reporting Person is still employed with the Issuer on the following dates, the RSUs shall vest over three years, with (i) one-third of the RSUs vesting on the one-year anniversary of the date of grant and (ii) the remaining RSUs shall vest in eight equal quarterly installments over the next two years, commencing with the first quarter following the first anniversary of the date of grant.

Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock.

Provided the Reporting Person is still employed with the Issuer on the following dates, the RSUs shall vest over three years, with (i) one-third of the RSUs vesting on the one-year anniversary of the date of grant and (ii) the remaining RSUs shall vest in eight equal quarterly installments over the next two years, commencing with the first quarter following the first anniversary of the date of grant.

Represents shares withheld by the Issuer to satisfy the mandatory tax withholding requirements upon vesting of the RSUs. This is not an open market sale of securities.

Represents common stock remaining after deducting the common stock withheld for taxes.

Each RSU represents a contingent right to receive one share of the Issuer's common stock.

The remaining RSUs will vest in equal quarterly installments.

Such aggregate number reflects the remainder of such RSUs granted on March 5, 2025, but does not include any other RSUs held by such Reporting Person.

Each RSU represents a contingent right to receive one share of the Issuer's common stock.

The remaining RSUs will vest in equal quarterly installments.

Such aggregate number reflects the remainder of such RSUs granted on March 5, 2025, but does not include any other RSUs held by such Reporting Person.

Represents such shares underlying the restricted stock units ("RSUs") which vested on the transaction date.

Represents such shares underlying the restricted stock units ("RSUs") which vested on the transaction date.

Represents such shares underlying the restricted stock units ("RSUs") which vested on the transaction date.