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TWO SIGMA INVESTMENTS, LP

Position in OPK — Opko Health, Inc.

CIK 1179392 NEW YORK, NY

Position in OPK

as of Mar 31, 2026 · filed May 15, 2026
Position Value
$193,800
-$731,981 QoQ
Shares Held
170,000
-76.9% QoQ
Ownership
0.023%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
not a current holder
Holding Since
Mar 2020
22 quarters on record
Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Common Shares in OPK Over Time

Shares Held

Position Value (USD)

Derivatives in OPK

reported options exposure · as of Mar 31, 2021
CallValue
$46,332
CallShares
10,800
PutValue
$51,909
PutShares
12,100

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Diagnostics & Research

Healthcare · as of Mar 31, 2026

TWO SIGMA INVESTMENTS, LP holds $1,108,346,968 across 33 Diagnostics & Research names. OPK ranks #31 (0.0% of the industry book) .

# Ticker Company Shares Value (USD) Open

All Filings in OPK

Export CSV
25 filing rows on record
Report Date Value (USD) Shares
2026-03-31 $193,800 170,000
2025-12-31 $925,781 734,747
2025-09-30 $1,946,252 1,255,647
2025-06-30 $2,424,506 1,836,747
2025-03-31 $2,731,986 1,645,775
2024-12-31 $2,421,923 1,647,567
2024-09-30 $1,039,865 697,896
2024-06-30 $758,110 606,488
2024-03-31 $1,961,624 1,634,687
2023-12-31 $1,462,910 968,815
2023-09-30 $2,304,291 1,440,182
2023-06-30 $3,459,989 1,594,465
2023-03-31 $2,809,732 1,924,474
2022-12-31 $2,836,270 2,269,016
2022-09-30 $5,457,127 2,887,369
2022-06-30 $4,290,728 1,695,940
2021-09-30 $64,984 17,804
2021-06-30 $72,106 17,804
2021-03-31 $46,332 10,800
2021-03-31 $51,909 12,100
2021-03-31 $187,490 43,704
2020-09-30 $36,900 10,000
2020-09-30 $4,087,449 1,107,710
2020-06-30 $3,573,901 1,048,065
2020-03-31 $3,899,028 2,909,723