D. E. Shaw & Co., Inc.

Position in SRPT — Sarepta Therapeutics, Inc.

CIK 1009207 New York, NY

Back to SRPT Full portfolio

Position in SRPT

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$10,335,695

-$22,813,497 QoQ

Shares Held

474,986

-69.2% QoQ

Ownership

0.450%

of shares outstanding

% of Portfolio

0.01%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Mar 2020

25 quarters on record

Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Common Shares in SRPT Over Time

Shares Held

Position Value (USD)

Derivatives in SRPT

reported options exposure · as of Mar 31, 2026

CallValue

CallShares

PutValue

$2,759,168

PutShares

126,800

Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.

Position in Biotechnology

Healthcare · as of Mar 31, 2026

D. E. Shaw & Co., Inc. holds $4,371,472,260 across 180 Biotechnology names. SRPT ranks #61 (0.2% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	INSM	INSMED Inc	5,625,825	$919,934,903
2	ALNY	Alnylam Pharmaceuticals, Inc.	1,059,062	$350,411,843
3	BBIO	BridgeBio Pharma, Inc.	2,545,486	$189,027,789
4	PCVX	Vaxcyte, Inc.	2,865,318	$166,503,628
5	EXEL	Exelixis, Inc.	3,603,063	$154,535,371
6	HALO	Halozyme Therapeutics, Inc.	1,868,708	$120,774,597
7	PTCT	Ptc Therapeutics, Inc.	1,640,381	$111,759,157
8	VRTX	Vertex Pharmaceuticals Inc / Ma	248,960	$111,170,598

All Filings in SRPT

Export CSV

38 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$10,335,695	474,986	+274.6%	Shares	Defined	2026-05-15
2026-03-31	$2,759,168	126,800	-91.8%	Put	Defined	2026-05-15
2025-12-31	$33,149,192	1,540,390	+1897.9%	Shares	Defined	2026-02-17
2025-12-31	$1,659,192	77,100	-96.2%	Put	Defined	2026-02-17
2025-09-30	$38,675,371	2,007,025	+2300.7%	Shares	Defined	2025-11-14
2025-09-30	$1,610,972	83,600	-98.1%	Put	Defined	2025-11-14
2025-06-30	$76,584,709	4,478,638	+5077.6%	Shares	Defined	2025-08-14
2025-06-30	$1,479,150	86,500	+1863.2%	Put	Defined	2025-08-14
2025-03-31	$281,190	4,406	+25.9%	Shares	Defined	2025-05-15
2024-12-31	$425,565	3,500	-83.9%	Shares	Defined	2025-02-14
2024-09-30	$2,714,982	21,739	-81.6%	Shares	Defined	2024-11-14
2024-06-30	$18,618,720	117,840	+35.7%	Shares	Defined	2024-08-14
2024-03-31	$11,245,672	86,866	-75.6%	Shares	Defined	2024-05-15
2023-12-31	$34,284,046	355,533	+285.8%	Shares	Defined	2024-02-14
2023-09-30	$11,171,392	92,158	-66.5%	Shares	Defined	2023-11-14
2023-06-30	$31,483,723	274,919	-67.7%	Shares	Defined	2023-08-14
2023-03-31	$117,394,910	851,737	+8417.4%	Shares	Defined	2023-05-15
2022-12-31	$1,295,800	10,000	-98.3%	Call	Defined	2023-02-14
2022-12-31	$75,447,566	582,247	-8.0%	Shares	Defined	2023-02-14
2022-09-30	$69,956,454	632,861	+6228.6%	Shares	Defined	2022-11-14
2022-09-30	$1,105,400	10,000	0.0%	Call	Defined	2022-11-14
2022-09-30	$1,105,400	10,000	-96.2%	Put	Defined	2022-11-14
2022-06-30	$19,600,765	261,483	-10.3%	Shares	Defined	2022-08-15
2022-03-31	$22,764,792	291,408	-18.6%	Shares	Defined	2022-05-16
2021-12-31	$32,246,454	358,095	+306.9%	Shares	Defined	2022-02-14
2021-09-30	$8,138,055	87,998	+294.3%	Shares	Defined	2021-11-15
2021-06-30	$1,735,001	22,318	+64.3%	Shares	Defined	2021-08-16
2021-03-31	$1,012,564	13,586	+35.9%	Shares	Defined	2021-05-17
2020-12-31	$1,704,900	10,000	-56.6%	Call	Defined	2021-02-16
2020-12-31	$3,931,499	23,060	+130.6%	Shares	Defined	2021-02-16
2020-09-30	$1,404,300	10,000	+5.8%	Call	Defined	2020-11-16
2020-09-30	$1,327,344	9,452	-83.6%	Shares	Defined	2020-11-16
2020-06-30	$9,246,487	57,668	+476.7%	Shares	Defined	2020-08-14
2020-06-30	$1,603,400	10,000	0.0%	Put	Defined	2020-08-14
2020-06-30	$1,603,400	10,000	-16.7%	Call	Defined	2020-08-14
2020-03-31	$1,173,840	12,000	-61.4%	Call	Defined	2020-05-15
2020-03-31	$3,038,289	31,060	-61.2%	Shares	Defined	2020-05-15
2020-03-31	$7,835,382	80,100	—	Put	Defined	2020-05-15
No filing history on record for this holder in this stock.