NEW YORK STATE COMMON RETIREMENT FUND

Pension

Position in SYRE — Spyre Therapeutics, Inc.

CIK 810265 ALBANY, NY

Position in SYRE

as of Jun 30, 2026 · filed Jul 29, 2026 Compact

Position Value

$2,322,928

+$1,199,882 QoQ

Shares Held

26,165

+17.5% QoQ

Ownership

0.030%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

of 24 holders

Holding Since

Dec 2023

11 quarters on record

Voting authority Sole 100% Shared 0% None 0%

Healthcare · as of Jun 30, 2026

NEW YORK STATE COMMON RETIREMENT FUND holds $953,600,073 across 287 Biotechnology names. SYRE ranks #57 (0.2% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	VRTX	Vertex Pharmaceuticals Inc / Ma	277,614	$137,899,202
2	REGN	Regeneron Pharmaceuticals, Inc.	111,369	$69,443,026
3	ASND	Ascendis Pharma A/S	191,791	$51,154,495
4	MDGL	Madrigal Pharmaceuticals, Inc.	94,743	$50,872,253
5	LGND	Ligand Pharmaceuticals Inc	137,258	$43,385,881
6	IONS	Ionis Pharmaceuticals Inc	500,050	$39,648,964
7	INSM	INSMED Inc	304,236	$32,437,642
8	MIRM	Mirum Pharmaceuticals, Inc.	250,558	$29,332,825

11 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-06-30	$2,322,928	26,165	+17.5%	Shares	Sole	2026-07-29
2026-03-31	$1,123,046	22,265	+16.2%	Shares	Sole	2026-05-06
2025-12-31	$627,845	19,165	+15.7%	Shares	Sole	2026-02-12
2025-09-30	$277,629	16,565	0.0%	Shares	Sole	2025-11-03
2025-06-30	$247,978	16,565	+61.4%	Shares	Sole	2025-10-08
2025-03-31	$165,625	10,265	0.0%	Shares	Sole	2025-10-08
2024-12-31	$238,969	10,265	0.0%	Shares	Sole	2025-10-08
2024-09-30	$301,893	10,265	-28.5%	Shares	Sole	2025-10-08
2024-06-30	$337,721	14,365	-2.1%	Shares	Sole	2025-10-08
2024-03-31	$556,433	14,670	+3919.2%	Shares	Sole	2025-10-08
2023-12-31	$7,854	365	—	Shares	Sole	2025-10-08
No filing history on record for this holder in this stock.